Very low levels of methylmercury induce cell death of cultured rat cerebellar neurons via calpain activation

Toxicology

Volumn 213, Issue 1-2, 2005, Pages 97-106

  Sakaue, Motoharu ^a   Okazaki, Maiko ^a   Hara, Shuntaro ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Calpain; Cerebellar granule neurons; Cyclin dependent kinase 5; Methylmercury; p35; Very low concentration neurotoxicity

Indexed keywords

ANTIBODY; CALCIUM ION; CALPAIN; CALPASTATIN; CYCLIN DEPENDENT KINASE 5; FODRIN; METHYLMERCURY; PHOSPHOTRANSFERASE; PROTEIN P25; PROTEIN P35; PROTEIN SUBUNIT; TAU PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CALCIUM CELL LEVEL; CELL ACTIVATION; CELL CULTURE; CELL DEATH; CEREBELLUM; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; EXPOSURE; GRANULE CELL; IMMUNOBLOTTING; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; APOPTOSIS; CALCIUM; CALPAIN; CARRIER PROTEINS; CELL SURVIVAL; CEREBELLAR CORTEX; CYSTEINE PROTEINASE INHIBITORS; ENZYME ACTIVATION; IMMUNOBLOTTING; METHYLMERCURY COMPOUNDS; MICROFILAMENT PROTEINS; NERVE TISSUE PROTEINS; NEURONS; OLIGOPEPTIDES; RATS; RATS, WISTAR; SPECTROMETRY, FLUORESCENCE; TAU PROTEINS;

EID: 23944441220     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2005.05.013     Document Type: Article

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