Involvement of independent mechanism upon poly(ADP-ribose) polymerase (PARP) activation in methylmercury cytotoxicity in rat cerebellar granule cell culture

Journal of Neuroscience Research

Volumn 86, Issue 15, 2008, Pages 3427-3434

  Sakaue, Motoharu ^a,b   Mori, Naoko ^b   Okazaki, Maiko ^b   Ishii, Mayuka ^b   Inagaki, Yayoi ^b   Iino, Yuka ^b   Miyahara, Kiyomi ^b   Yamamoto, Mai ^b   Kumagai, Takeshi ^b   Hara, Shuntaro ^c   Yamamoto, Masako ^a   Arishima, Kazuyoshi ^a  

^a AZABU UNIVERSITY   (Japan)

^b KITASATO UNIVERSITY   (Japan)

^c School of Pharmaceutical Sciences   (Japan)

Author keywords

Cerebellar granule cells; Cytotoxicity; IMR 32; Methylmercury; PARP inhibitor

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 1,5 DIHYDROISOQUINOLINE; 3 AMINOBENZAMIDE; 3,4 DIHYDRO 5 [4 (1 PIPERIDINYL)BUTOXY] 1 2H ISOQUINOLINE; BUTHIONINE SULFOXIMINE; GLUTATHIONE; MALEIC ACID DIETHYL ESTER; METHYLMERCURY; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; RADICAL; REACTIVE OXYGEN METABOLITE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CEREBELLUM; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; FLUORESCENCE MICROSCOPY; GRANULE CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INHIBITION KINETICS; NEUROBLASTOMA CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CELL DEATH; CELLS, CULTURED; CEREBELLUM; ENZYME ACTIVATION; ENZYME INHIBITORS; FREE RADICALS; GLUTATHIONE; HUMANS; ISOQUINOLINES; METHYLMERCURY COMPOUNDS; MICROSCOPY, FLUORESCENCE; NEURONS; PIPERIDINES; POLY(ADP-RIBOSE) POLYMERASES; RATS;

EID: 57049112557     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21780     Document Type: Article

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