메뉴 건너뛰기




Volumn 54, Issue 1, 2016, Pages 40-58

Yeast transcriptome and in vivo hypoxia detection reveals histoplasma capsulatum response to low oxygen tension

Author keywords

Histoplasma; Hypoxia; Hypoxyprobe; RNA seq

Indexed keywords

ABC TRANSPORTER; DNA BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NIT50 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTOR ERG; TRANSCRIPTION FACTOR ERG2; TRANSCRIPTION FACTOR ERG3; TRANSCRIPTOME; UNCLASSIFIED DRUG; OXYGEN;

EID: 84971577032     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.1093/mmy/myv073     Document Type: Article
Times cited : (24)

References (65)
  • 1
    • 0014201976 scopus 로고
    • Environmental factors and growth of Histoplasma capsulatumin soil
    • Norman L, Goodman HWL. Environmental factors and growth of Histoplasma capsulatumin soil. Mycopathol Mycol Appl 1967; 13: 145-156
    • (1967) Mycopathol Mycol Appl , vol.13 , pp. 145-156
    • Norman, L.1    Goodman, H.W.L.2
  • 2
    • 0034953642 scopus 로고    scopus 로고
    • The epidemiology of histoplasmosis: A review
    • Cano M V, Hajjeh RA. The epidemiology of histoplasmosis: a review. Semin Respir Infect 2001; 16: 109-118.
    • (2001) Semin Respir Infect , vol.16 , pp. 109-118
    • Cano, M.V.1    Hajjeh, R.A.2
  • 3
    • 0014035162 scopus 로고
    • Effect of temperature on the intracellular growth of Histoplasma capsulatum
    • Howard DH. Effect of temperature on the intracellular growth of Histoplasma capsulatum. J Bacteriol 1967; 93: 438-444.
    • (1967) J Bacteriol , vol.93 , pp. 438-444
    • Howard, D.H.1
  • 4
    • 0025099677 scopus 로고
    • Phagocytosis of Histoplasma capsulatumyeasts and microconidia by human cultured macrophages and alveolar macrophages. Cellular cytoskeleton requirement for attachment and ingestion
    • Newman SL, Bucher C, Rhodes J et al. Phagocytosis of Histoplasma capsulatumyeasts and microconidia by human cultured macrophages and alveolar macrophages. Cellular cytoskeleton requirement for attachment and ingestion. J Clin Invest 1990; 85: 223-230.
    • (1990) J Clin Invest , vol.85 , pp. 223-230
    • Newman, S.L.1    Bucher, C.2    Rhodes, J.3
  • 5
    • 67649497105 scopus 로고    scopus 로고
    • The interaction between Histoplasma capsulatumcell wall carbohydrates and host components: Relevance in the immunomodulatory role of histoplasmosis
    • Gorocica P, Taylor ML, Alvarado-Vásquez N et al. The interaction between Histoplasma capsulatumcell wall carbohydrates and host components: relevance in the immunomodulatory role of histoplasmosis. Mem Inst Oswaldo Cruz 2009; 104: 492-496.
    • (2009) Mem Inst Oswaldo Cruz , vol.104 , pp. 492-496
    • Gorocica, P.1    Taylor, M.L.2    Alvarado-Vásquez, N.3
  • 6
    • 0033082539 scopus 로고    scopus 로고
    • Macrophages in host defense against Histoplasma capsulatum
    • Newman SL. Macrophages in host defense against Histoplasma capsulatum. Trends Microbiol. 1999; 7: 67-71.
    • (1999) Trends Microbiol , vol.7 , pp. 67-71
    • Newman, S.L.1
  • 7
    • 84855371099 scopus 로고    scopus 로고
    • Histoplasma virulence and host responses
    • Mihu MR, Nosanchuk JD. Histoplasma virulence and host responses. Int J Microbiol 2012; 2012: 268123. doi: 10. 1155/ 2012/268123.
    • (2012) Int J Microbiol , vol.2012
    • Mihu, M.R.1    Nosanchuk, J.D.2
  • 8
    • 25444526364 scopus 로고    scopus 로고
    • Human dendritic cell activity against Histoplasma capsulatum is mediated via phagolysosomal fusion
    • Gildea LA, Ciraolo GM, Morris RE et al. Human dendritic cell activity against Histoplasma capsulatum is mediated via phagolysosomal fusion. Infect Immun 2005; 73: 6803-6811.
    • (2005) Infect Immun , vol.73 , pp. 6803-6811
    • Gildea, L.A.1    Ciraolo, G.M.2    Morris, R.E.3
  • 9
    • 0034519304 scopus 로고    scopus 로고
    • Host response and Histoplasma capsulatum/macrophage molecular interactions
    • Porta A, Maresca B. Host response and Histoplasma capsulatum/macrophage molecular interactions. Med Mycol 2000; 38: 399-406.
    • (2000) Med Mycol , vol.38 , pp. 399-406
    • Porta, A.1    Maresca, B.2
  • 10
    • 33644832153 scopus 로고    scopus 로고
    • Characterization of the tuberculous granuloma in murine and human lungs: Cellular composition and relative tissue oxygen tension
    • Tsai MC, Chakravarty S, Zhu G et al. Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension. Cell Microbiol 2006; 8: 218-232.
    • (2006) Cell Microbiol , vol.8 , pp. 218-232
    • Tsai, M.C.1    Chakravarty, S.2    Zhu, G.3
  • 11
    • 33747764168 scopus 로고    scopus 로고
    • Characterization of the Histoplasma capsulatum-induced granuloma
    • Heninger E, Hogan LH, Karman J et al. Characterization of the Histoplasma capsulatum-induced granuloma. J Immunol 2006; 177: 3303-3313.
    • (2006) J Immunol , vol.177 , pp. 3303-3313
    • Heninger, E.1    Hogan, L.H.2    Karman, J.3
  • 12
    • 0842346271 scopus 로고    scopus 로고
    • The immunological aspects of latency in tuberculosis
    • Chan J, Flynn J. The immunological aspects of latency in tuberculosis. Clin Immunol 2004; 110: 2-12.
    • (2004) Clin Immunol , vol.110 , pp. 2-12
    • Chan, J.1    Flynn, J.2
  • 13
    • 0034977241 scopus 로고    scopus 로고
    • MINIREVIEW Tuberculosis: Latency and Reactivation
    • Flynn JOAL, Chan J. MINIREVIEW Tuberculosis: Latency and Reactivation. Society 2001; 69: 4195-4201
    • (2001) Society , vol.69 , pp. 4195-4201
    • Flynn, J.O.A.L.1    Chan, J.2
  • 14
    • 0035160270 scopus 로고    scopus 로고
    • Tissue oxygen tension and brain sensitivity to hypoxia
    • Erecińska M, Silver IA. Tissue oxygen tension and brain sensitivity to hypoxia. Respir Physiol 2001; 128: 263-276.
    • (2001) Respir Physiol , vol.128 , pp. 263-276
    • Erecińska, M.1    Silver, I.A.2
  • 16
    • 33845741242 scopus 로고    scopus 로고
    • The cellular basis for diverse responses to oxygen
    • Chandel NS, Budinger GRS. The cellular basis for diverse responses to oxygen. Free Radic Biol Med 2007; 42: 165-174.
    • (2007) Free Radic Biol Med , vol.42 , pp. 165-174
    • Chandel, N.S.1    Budinger, G.R.S.2
  • 17
    • 2642555563 scopus 로고    scopus 로고
    • HIF1 and oxygen sensing in the brain
    • Sharp FR, Bernaudin M. HIF1 and oxygen sensing in the brain. Nat Rev Neurosci 2004; 5: 437-448.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 437-448
    • Sharp, F.R.1    Bernaudin, M.2
  • 18
    • 84971533355 scopus 로고
    • Regulation of gene expression by oxygen in Saccharomyces cerevisiae
    • Zitomer RS, Lowry C V. Regulation of gene expression by oxygen in Saccharomyces cerevisiae. Curr Genet 1992; 56: 388-393.
    • (1992) Curr Genet , vol.56 , pp. 388-393
    • Zitomer, R.S.1    Lowry, C.V.2
  • 19
    • 76149105866 scopus 로고    scopus 로고
    • Regulation of gene expression in response to oxygen tension
    • Hunter CN, Daldal F, Thurnauer MC, Beatty JT et al., (eds.). The Netherlands: Springer Science. ; (Purple Phototrophic Bacteria)
    • Bauer CE, Setterdahl A, Wu J Regulation of gene expression in response to oxygen tension. In: Hunter CN, Daldal F, Thurnauer MC, Beatty JT et al., (eds.). Adv Photosynth Respir. The Netherlands: Springer Science. 2009; 28(Purple Phototrophic Bacteria): 707-725.
    • (2009) Adv Photosynth Respir , vol.28 , pp. 707-725
    • Bauer, C.E.1    Setterdahl, A.2    Wu, J.3
  • 20
    • 0344584297 scopus 로고    scopus 로고
    • Oxygen and the regulation of gene expression in wounds
    • Albina JE, Reichner JS. Oxygen and the regulation of gene expression in wounds. Wound Repair Regen 2003; 11: 445-451.
    • (2003) Wound Repair Regen , vol.11 , pp. 445-451
    • Albina, J.E.1    Reichner, J.S.2
  • 21
    • 0033808725 scopus 로고    scopus 로고
    • Oxygen regulation of gene expression: A study in opposites
    • D'Angio CT, Finkelstein JN. Oxygen regulation of gene expression: a study in opposites. Mol Genet Metab 2000; 71: 371-380.
    • (2000) Mol Genet Metab , vol.71 , pp. 371-380
    • D'Angio, C.T.1    Finkelstein, J.N.2
  • 22
    • 57149083070 scopus 로고    scopus 로고
    • A sterolregulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus
    • Willger SD, Puttikamonkul S, Kim K-H et al. A sterolregulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus. PLoS Pathog 2008; 4: e1000200. doi: 10. 1371/journal. ppat. 1000200.
    • (2008) PLoS Pathog , vol.4
    • Willger, S.D.1    Puttikamonkul, S.2    Kim, K.-H.3
  • 23
    • 84856569061 scopus 로고    scopus 로고
    • Transcriptomic and proteomic analyses of the Aspergillus fumigatushypoxia response using an oxygen-controlled fermenter
    • Barker BM, Kroll K, Vödisch M et al. Transcriptomic and proteomic analyses of the Aspergillus fumigatushypoxia response using an oxygen-controlled fermenter. BMC Genomics 2012; 13: 62. doi: 10. 1186/1471-2164-13-62.
    • (2012) BMC Genomics , vol.13 , pp. 62
    • Barker, B.M.1    Kroll, K.2    Vödisch, M.3
  • 24
    • 79960941562 scopus 로고    scopus 로고
    • In vivo Hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis
    • Grahl N, Puttikamonkul S, Macdonald JM et al. In vivo Hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis. PLoS Pathog 2011; 7: e1002145. doi: 10. 1371/journal. ppat. 1002145.
    • (2011) PLoS Pathog , vol.7
    • Grahl, N.1    Puttikamonkul, S.2    Macdonald, J.M.3
  • 26
    • 33847335459 scopus 로고    scopus 로고
    • A link between virulence and homeostatic responses to hypoxia during infection by the human fungal pathogen Cryptococcus neoformans
    • Chun CD, Liu OW, Madhani HD. A link between virulence and homeostatic responses to hypoxia during infection by the human fungal pathogen Cryptococcus neoformans. PLoS Pathog 2007; 3: e22. doi: 10. 1371/journal. ppat. 0030022.
    • (2007) PLoS Pathog , vol.3
    • Chun, C.D.1    Liu, O.W.2    Madhani, H.D.3
  • 27
    • 34247547435 scopus 로고    scopus 로고
    • Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans
    • Chang YC, Bien CM, Lee H et al. Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans. Mol Microbiol 2007; 64: 614-629.
    • (2007) Mol Microbiol , vol.64 , pp. 614-629
    • Chang, Y.C.1    Bien, C.M.2    Lee, H.3
  • 28
    • 33748888161 scopus 로고    scopus 로고
    • A role for sterol levels in oxygen sensing in Saccharomyces cerevisiae
    • Davies BSJ, Rine J. A role for sterol levels in oxygen sensing in Saccharomyces cerevisiae. Genetics 2006; 174: 191-201.
    • (2006) Genetics , vol.174 , pp. 191-201
    • Davies, B.S.J.1    Rine, J.2
  • 29
    • 77649296829 scopus 로고    scopus 로고
    • Sterol regulatory element binding proteins in fungi: Hypoxic transcription factors linked to pathogenesis
    • Bien CM, Espenshade PJ. Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesis. Eukaryot Cell 2010; 9: 352-359.
    • (2010) Eukaryot Cell , vol.9 , pp. 352-359
    • Bien, C.M.1    Espenshade, P.J.2
  • 30
    • 17644401005 scopus 로고    scopus 로고
    • SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast
    • Hughes AL, Todd BL, Espenshade PJ. SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast. Cell 2005; 120: 831-842.
    • (2005) Cell , vol.120 , pp. 831-842
    • Hughes, A.L.1    Todd, B.L.2    Espenshade, P.J.3
  • 31
    • 18244396070 scopus 로고    scopus 로고
    • Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes
    • MacPherson S, Akache B, Weber S et al. Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes. Antimicrob Agents Chemother. 2005; 49: 1745-1752.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 1745-1752
    • MacPherson, S.1    Akache, B.2    Weber, S.3
  • 32
    • 33845659996 scopus 로고    scopus 로고
    • Candida albicanstranscription factor Ace2 regulates metabolism and is required for filamentation in hypoxic conditions
    • Mulhern SM, Logue ME, Butler G. Candida albicanstranscription factor Ace2 regulates metabolism and is required for filamentation in hypoxic conditions. Eukaryot Cell 2006; 5: 2001-2013.
    • (2006) Eukaryot Cell , vol.5 , pp. 2001-2013
    • Mulhern, S.M.1    Logue, M.E.2    Butler, G.3
  • 33
    • 77953794078 scopus 로고    scopus 로고
    • Transcriptional response to hypoxia in the aquatic fungus Blastocladiella emersonii
    • Camilo CM, Gomes SL. Transcriptional response to hypoxia in the aquatic fungus Blastocladiella emersonii. Eukaryot Cell 2010; 9: 915-925.
    • (2010) Eukaryot Cell , vol.9 , pp. 915-925
    • Camilo, C.M.1    Gomes, S.L.2
  • 34
    • 46249108568 scopus 로고    scopus 로고
    • Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates
    • Via LE, Lin PL, Ray SM et al. Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates. Infect Immun 2008; 76: 2333-2340.
    • (2008) Infect Immun , vol.76 , pp. 2333-2340
    • Via, L.E.1    Lin, P.L.2    Ray, S.M.3
  • 35
    • 33750503812 scopus 로고    scopus 로고
    • Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice
    • Aly S, Wagner K, Keller C et al. Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice. J Pathol 2006; 210: 298-305.
    • (2006) J Pathol , vol.210 , pp. 298-305
    • Aly, S.1    Wagner, K.2    Keller, C.3
  • 36
    • 80052496075 scopus 로고    scopus 로고
    • Metabolic profiling of lung granuloma in Mycobacterium tuberculosis infected guinea pigs: Ex vivo 1H magic angle spinning NMR studies
    • Somashekar BS, Amin AG, Rithner CD et al. Metabolic profiling of lung granuloma in Mycobacterium tuberculosis infected guinea pigs: ex vivo 1H magic angle spinning NMR studies. J Proteome Res 2011; 10: 4186-4195.
    • (2011) J Proteome Res , vol.10 , pp. 4186-4195
    • Somashekar, B.S.1    Amin, A.G.2    Rithner, C.D.3
  • 37
    • 72449173927 scopus 로고    scopus 로고
    • Conservation of the sterol regulatory element-binding protein pathway and its pathobiological importance in cryptococcus neoformans
    • Chang YC, Ingavale SS, Bien C et al. Conservation of the sterol regulatory element-binding protein pathway and its pathobiological importance in cryptococcus neoformans. Eukaryot Cell 2009; 8: 1770-1779.
    • (2009) Eukaryot Cell , vol.8 , pp. 1770-1779
    • Chang, Y.C.1    Ingavale, S.S.2    Bien, C.3
  • 38
    • 68949133030 scopus 로고    scopus 로고
    • Degradation of {SREBP}precursor requires the{ERAD}components{Ubc7} and{Hrd1}in fission yeast
    • Hughes BT, Nwosu CC, Espenshade PJ. Degradation of {SREBP}precursor requires the{ERAD}components{Ubc7} and{Hrd1}in fission yeast. J Biol Chem 2009; 284: 20512-20521.
    • (2009) J Biol Chem , vol.284 , pp. 20512-20521
    • Hughes, B.T.1    Nwosu, C.C.2    Espenshade, P.J.3
  • 39
    • 33645222762 scopus 로고    scopus 로고
    • Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast
    • Todd BL, Stewart EV, Burg JS et al. Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast. Mol Cell Biol 2006; 26: 2817. doi: 10. 1128/MCB. 26. 7. 2817.
    • (2006) Mol Cell Biol , vol.26 , pp. 2817
    • Todd, B.L.1    Stewart, E.V.2    Burg, J.S.3
  • 40
    • 58349092088 scopus 로고    scopus 로고
    • Responses to hypoxia in fungal pathogens
    • Ernst JF, Tielker D. Responses to hypoxia in fungal pathogens. Cell Microbiol 2009; 11: 183-190.
    • (2009) Cell Microbiol , vol.11 , pp. 183-190
    • Ernst, J.F.1    Tielker, D.2
  • 41
    • 71549164363 scopus 로고    scopus 로고
    • Transcriptional regulation of carbohydrate metabolism in the human pathogen Candida albicans
    • Askew C, Sellam A, Epp E et al. Transcriptional regulation of carbohydrate metabolism in the human pathogen Candida albicans. PLoS Pathog 2009; 5: e1000612.
    • (2009) PLoS Pathog , vol.5
    • Askew, C.1    Sellam, A.2    Epp, E.3
  • 42
    • 84055223912 scopus 로고    scopus 로고
    • Using RNA-seq to determine the transcriptional landscape and the hypoxic response of the pathogenic yeast Candida parapsilosis
    • Guida A, Lindstädt C, Maguire SL et al. Using RNA-seq to determine the transcriptional landscape and the hypoxic response of the pathogenic yeast Candida parapsilosis. BMC Genomics 2011; 12: 628.
    • (2011) BMC Genomics , vol.12 , pp. 628
    • Guida, A.1    Lindstädt, C.2    Maguire, S.L.3
  • 43
    • 0033545977 scopus 로고    scopus 로고
    • Oxygen sensing in yeast: Evidence for the involvement of the respiratory chain in regulating the transcription of a subset of hypoxic genes
    • Kwast KE, Burke P V, Staahl BT et al. Oxygen sensing in yeast: evidence for the involvement of the respiratory chain in regulating the transcription of a subset of hypoxic genes. Proc Natl Acad Sci U S A1999; 96: 5446-5451.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5446-5451
    • Kwast, K.E.1    Burke, P.V.2    Staahl, B.T.3
  • 44
    • 0032052761 scopus 로고    scopus 로고
    • Oxygen sensing and the transcriptional regulation of oxygen-responsive genes in yeast
    • Kwast KE, Burke P V, Poyton RO. Oxygen sensing and the transcriptional regulation of oxygen-responsive genes in yeast. J Exp Biol 1998; 201: 1177-1195.
    • (1998) J Exp Biol , vol.201 , pp. 1177-1195
    • Kwast, K.E.1    Burke, P.V.2    Poyton, R.O.3
  • 46
    • 84884522638 scopus 로고    scopus 로고
    • Hypoxia and gene expression in eukaryotic microbes
    • Butler G. Hypoxia and gene expression in eukaryotic microbes. Annu Rev Microbiol 2013; 67: 291-312.
    • (2013) Annu Rev Microbiol , vol.67 , pp. 291-312
    • Butler, G.1
  • 47
    • 84907123709 scopus 로고
    • Quantitative plating of Histoplasma capsulatumwithout addition of conditioned medium or siderophores
    • Worsham PL, Goldman WE. Quantitative plating of Histoplasma capsulatumwithout addition of conditioned medium or siderophores. J Med Vet Mycol 1988; 26: 137-143.
    • (1988) J Med Vet Mycol , vol.26 , pp. 137-143
    • Worsham, P.L.1    Goldman, W.E.2
  • 48
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-Seq
    • Trapnell C, Pachter L, Salzberg SL. TopHat: Discovering splice junctions with RNA-Seq. Bioinformatics 2009; 25: 1105-1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 49
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcriptand isoform switching during cell differentiation
    • Trapnell C, Williams BA, Pertea G et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcriptand isoform switching during cell differentiation. Nat Biotechnol 2010; 28: 511-515.
    • (2010) Nat Biotechnol , vol.28 , pp. 511-515
    • Trapnell, C.1    Williams, B.A.2    Pertea, G.3
  • 50
    • 80051941094 scopus 로고    scopus 로고
    • Identification of novel transcripts in annotated genomes using RNA-seq
    • Roberts A, Pimentel H, Trapnell C et al. Identification of novel transcripts in annotated genomes using RNA-seq. Bioinformatics 2011; 27: 2325-2329.
    • (2011) Bioinformatics , vol.27 , pp. 2325-2329
    • Roberts, A.1    Pimentel, H.2    Trapnell, C.3
  • 51
    • 79952709611 scopus 로고    scopus 로고
    • Improving RNASeq expression estimates by correcting for fragment bias
    • Roberts A, Trapnell C, Donaghey J et al. Improving RNASeq expression estimates by correcting for fragment bias. Genome Biol 2011; 12: R22. doi: 10. 1186/gb-2011-12-3-r22.
    • (2011) Genome Biol , vol.12
    • Roberts, A.1    Trapnell, C.2    Donaghey, J.3
  • 53
    • 80052978224 scopus 로고    scopus 로고
    • Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
    • Cabili M, Trapnell C, Goff L et al. Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. Genes Dev 2011; 25: 1915-1927.
    • (2011) Genes Dev , vol.25 , pp. 1915-1927
    • Cabili, M.1    Trapnell, C.2    Goff, L.3
  • 54
    • 0028785458 scopus 로고
    • Evidence that hypoxia markers detect oxygen gradients in liver: Pimonidazole and retrograde perfusion of rat liver
    • Arteel GE, Thurman RG, Yates JM et al. Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver. Br J Cancer 1995; 72: 889-895.
    • (1995) Br J Cancer , vol.72 , pp. 889-895
    • Arteel, G.E.1    Thurman, R.G.2    Yates, J.M.3
  • 56
    • 0029896110 scopus 로고    scopus 로고
    • Hepatic granulomas in murine visceral leishmaniasis caused by Leishmania chagasi
    • Wilson ME, Weinstock J V. Hepatic granulomas in murine visceral leishmaniasis caused by Leishmania chagasi. Methods 1996; 9: 248-254.
    • (1996) Methods , vol.9 , pp. 248-254
    • Wilson, M.E.1    Weinstock, J.V.2
  • 57
    • 44349091967 scopus 로고    scopus 로고
    • Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member
    • Hughes BT, Espenshade PJ. Oxygen-regulated degradation of fission yeast SREBP by Ofd1, a prolyl hydroxylase family member. EMBO J2008; 27: 1491-1501.
    • (2008) EMBO J , vol.27 , pp. 1491-1501
    • Hughes, B.T.1    Espenshade, P.J.2
  • 58
    • 26244443695 scopus 로고    scopus 로고
    • Identification of Histoplasma capsulatumtranscripts induced in response to reactive nitrogen species
    • Nittler MP, Hocking-Murray D, Foo CK et al. Identification of Histoplasma capsulatumtranscripts induced in response to reactive nitrogen species. Mol Biol Cell 2005; 16: 4792-4813.
    • (2005) Mol Biol Cell , vol.16 , pp. 4792-4813
    • Nittler, M.P.1    Hocking-Murray, D.2    Foo, C.K.3
  • 59
    • 69049108875 scopus 로고    scopus 로고
    • Foamy macrophages and the progression of the human tuberculosis granuloma
    • Russell DG, Cardona P, Kim M et al. Foamy macrophages and the progression of the human tuberculosis granuloma. Nat Immunol 2009; 10: 943-948.
    • (2009) Nat Immunol , vol.10 , pp. 943-948
    • Russell, D.G.1    Cardona, P.2    Kim, M.3
  • 60
    • 0030012686 scopus 로고    scopus 로고
    • Cytokine secretion and adhesion molecule expression by granuloma T lymphocytes in Mycobacterium aviuminfection
    • Sacco RE, Jensen RJ, Thoen CO et al. Cytokine secretion and adhesion molecule expression by granuloma T lymphocytes in Mycobacterium aviuminfection. Am J Pathol 1996; 148: 1935-1948.
    • (1996) Am J Pathol , vol.148 , pp. 1935-1948
    • Sacco, R.E.1    Jensen, R.J.2    Thoen, C.O.3
  • 63
    • 0014134149 scopus 로고
    • Laboratory examination of organic fungicides against zoopathogenic fungi in soil
    • Morehart AL, Larsh HW. Laboratory examination of organic fungicides against zoopathogenic fungi in soil. Appl Microbiol 1967; 15: 1248-1251.
    • (1967) Appl Microbiol , vol.15 , pp. 1248-1251
    • Morehart, A.L.1    Larsh, H.W.2
  • 64
    • 0033435198 scopus 로고    scopus 로고
    • Induction of hypoxiainducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain
    • Bergeron M, Yu AY, Solway KE et al. Induction of hypoxiainducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brain. Eur J Neurosci 1999; 11: 4159-4170.
    • (1999) Eur J Neurosci , vol.11 , pp. 4159-4170
    • Bergeron, M.1    Yu, A.Y.2    Solway, K.E.3
  • 65
    • 0142027805 scopus 로고    scopus 로고
    • Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
    • Horton JD, Shah NA, Warrington JA et al. Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes. Proc Natl Acad Sci U SA2003; 100: 12027-12032
    • (2003) Proc Natl Acad Sci U SA , vol.100 , pp. 12027-12032
    • Horton, J.D.1    Shah, N.A.2    Warrington, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.