Dephosphorylation of the adaptor LAT and phospholipase C-g by SHP-1 inhibits natural killer cell cytotoxicity

Science Signaling

Volumn 9, Issue 429, 2016, Pages

  Matalon, Omri ^a   Fried, Sophia ^a   Ben Shmuel, Aviad ^a   Pauker, Maor H ^a   Joseph, Noah ^a   Keizer, Danielle ^a   Piterburg, Marina ^a   Barda Saad, Mira ^a  

^a BAR ILAN UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; LAT PROTEIN; PHOSPHOLIPASE C GAMMA1; PROTEIN TYROSINE PHOSPHATASE; UBIQUITIN PROTEIN LIGASE E3; CALCIUM; DNA; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL1; KIR2DL1 PROTEIN, HUMAN; LAT PROTEIN, HUMAN; MEMBRANE PROTEIN; PHOSPHOLIPASE C GAMMA; PLCG1 PROTEIN, HUMAN; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASE SHP 1; SIGNAL TRANSDUCING ADAPTOR PROTEIN; UBIQUITIN;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; UBIQUITINATION; CELL LINE; CONFOCAL MICROSCOPY; CYTOLOGY; FLOW CYTOMETRY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETIC TRANSFECTION; IMAGE PROCESSING; LYMPHOCYTE ACTIVATION; METABOLISM; MUTAGENESIS; MUTATION; PHOSPHORYLATION; RNA INTERFERENCE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CALCIUM; CELL LINE; DNA; FLOW CYTOMETRY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; MUTAGENESIS; MUTATION; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RECEPTORS, KIR2DL1; RNA INTERFERENCE; TRANSFECTION; UBIQUITIN;

EID: 84971326457     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aad6182     Document Type: Article

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