Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells

Biochemical Journal

Volumn 356, Issue 2, 2001, Pages 461-471

  Paz, P E ^a   Wang, S ^a   Clarke, H ^a   Lu, X ^a   Stokoe, D ^a   Abo, A ^a  

^a ONYX PHARMACEUTICALS   (United States)

Author keywords

Phospholipase C 1; Ras signalling pathways; Tyrosine phosphorylation; Vav

Indexed keywords

BIOLOGICAL MEMBRANES; PHOSPHORESCENCE; PROTEINS;

SIGNALLING COMPLEXES;

BIOCHEMISTRY;

CELL PROTEIN; LAT PROTEIN; PHENYLALANINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEIN KINASE ZAP 70; PROTEIN P85; PROTEIN TYROSINE KINASE; RAS PROTEIN; SIGNAL PEPTIDE; T LYMPHOCYTE RECEPTOR; TYROSINE; UNCLASSIFIED DRUG; VAV PROTEIN;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; T LYMPHOCYTE ACTIVATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CARRIER PROTEINS; DNA PRIMERS; ENZYME PRECURSORS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOENZYMES; JURKAT CELLS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDE MAPPING; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; RAS PROTEINS; RECOMBINANT FUSION PROTEINS; SRC HOMOLOGY DOMAINS; T-LYMPHOCYTES; TYROSINE; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 0035365877     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3560461     Document Type: Article

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