Impact of diabetes mellitus

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 6, 2016, Pages 1049-1053

  Kanter, Jenny E ^a   Bornfeldt, Karin E ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

atherosclerosis; endothelial cell; high density lipoprotein; macrophage; microRNA; triglycerides

Indexed keywords

APOLIPOPROTEIN C3; GLUCOSE; INTERFERON; JANUS KINASE; MESSENGER RNA; MICRORNA; MICRORNA 191; MICRORNA 200B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPPRESSOR OF CYTOKINE SIGNALING 1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UNTRANSLATED RNA; VASCULAR ENDOTHELIAL CADHERIN; LIPOPROTEIN;

DIABETES MELLITUS; DISEASE ASSOCIATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; GLUCOSE BLOOD LEVEL; HUMAN; HYPERGLYCEMIA; HYPERTRIGLYCERIDEMIA; INFLAMMATION; INSULIN DEFICIENCY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; META ANALYSIS (TOPIC); NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR DISEASE; VASCULAR SMOOTH MUSCLE CELL; ANIMAL; BLOOD; DIABETIC ANGIOPATHY; EXPERIMENTAL DIABETES MELLITUS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RISK FACTOR;

ANIMALS; DIABETES MELLITUS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC ANGIOPATHIES; ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; LIPOPROTEINS; RISK FACTORS;

EID: 84971265215     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.116.307302     Document Type: Review

References (42)

1. Brownlee M, The pathobiology of diabetic complications: a unifying mechanism. Diabetes 2005 54 1615 1625
2. Johnstone MT, Creager SJ, Scales KM, Cusco JA, Lee BK, Creager MA, Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. Circulation 1993 88 2510 2516
3. Calver A, Collier J, Vallance P, Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes. J Clin Invest 1992 90 2548 2554. doi: 10.1172/JCI116149
4. Mäkimattila S, Liu ML, Vakkilainen J, Schlenzka A, Lahdenperä S, Syvänne M, Mäntysaari M, Summanen P, Bergholm R, Taskinen MR, Yki-Järvinen H, Impaired endothelium-dependent vasodilation in type 2 diabetes. Relation to LDL size, oxidized LDL, and antioxidants. Diabetes Care 1999 22 973 981
5. Loader J, Montero D, Lorenzen C, Watts R, Méziat C, Reboul C, Stewart S, Walther G, Acute hyperglycemia impairs vascular function in healthy and cardiometabolic diseased subjects: systematic review and meta-analysis. Arterioscler Thromb Vasc Biol 2015 35 2060 2072. doi: 10.1161/ATVBAHA.115.305530
6. Walther G, Obert P, Dutheil F, Chapier R, Lesourd B, Naughton G, Courteix D, Vinet A, Metabolic syndrome individuals with and without type 2 diabetes mellitus present generalized vascular dysfunction: cross-sectional study. Arterioscler Thromb Vasc Biol 2015 35 1022 1029. doi: 10.1161/ATVBAHA.114.304591
7. Kumar S, Kim CW, Simmons RD, Jo H, Role of flow-sensitive microRNAs in endothelial dysfunction and atherosclerosis: mechanosensitive athero-miRs. Arterioscler Thromb Vasc Biol 2014 34 2206 2216. doi: 10.1161/ATVBAHA.114.303425
8. Floris I, Descamps B, Vardeu A, Mitić T, Posadino AM, Shantikumar S, Sala-Newby G, Capobianco G, Mangialardi G, Howard L, Dessole S, Urrutia R, Pintus G, Emanueli C, Gestational diabetes mellitus impairs fetal endothelial cell functions through a mechanism involving microRNA-101 and histone methyltransferase enhancer of zester homolog-2. Arterioscler Thromb Vasc Biol 2015 35 664 674. doi: 10.1161/ATVBAHA.114.304730
9. Reddy MA, Das S, Zhuo C, Jin W, Wang M, Lanting L, Natarajan R, Regulation of vascular smooth muscle cell dysfunction under diabetic conditions by miR-504. Arterioscler Thromb Vasc Biol 2016 36 864 873. doi: 10.1161/ATVBAHA.115.306770
10. Yan MS, Marsden PA, Epigenetics in the vascular endothelium: looking from a different perspective in the epigenomics era. Arterioscler Thromb Vasc Biol 2015 35 2297 2306. doi: 10.1161/ATVBAHA.115.305043
11. Dangwal S, Stratmann B, Bang C, Lorenzen JM, Kumarswamy R, Fiedler J, Falk CS, Scholz CJ, Thum T, Tschoepe D, Impairment of wound healing in patients with type 2 diabetes mellitus influences circulating microRNA patterns via inflammatory cytokines. Arterioscler Thromb Vasc Biol 2015 35 1480 1488. doi: 10.1161/ATVBAHA.114.305048
12. Bretón-Romero R, Feng B, Holbrook M, Farb MG, Fetterman JL, Linder EA, Berk BD, Masaki N, Weisbrod RM, Inagaki E, Gokce N, Fuster JJ, Walsh K, Hamburg NM, Endothelial dysfunction in human diabetes is mediated by Wnt5a-JNK signaling. Arterioscler Thromb Vasc Biol 2016 36 561 569. doi: 10.1161/ATVBAHA.115.306578
13. Karki S, Farb MG, Ngo DT, Myers S, Puri V, Hamburg NM, Carmine B, Hess DT, Gokce N, Forkhead box O-1 modulation improves endothelial insulin resistance in human obesity. Arterioscler Thromb Vasc Biol 2015 35 1498 1506. doi: 10.1161/ATVBAHA.114.305139
14. Xia N, Horke S, Habermeier A, Closs EI, Reifenberg G, Gericke A, Mikhed Y, Münzel T, Daiber A, Förstermann U, Li H, Uncoupling of endothelial nitric oxide synthase in perivascular adipose tissue of diet-induced obese mice. Arterioscler Thromb Vasc Biol 2016 36 78 85. doi: 10.1161/ATVBAHA.115.306263
15. Chiu AP, Wan A, Lal N, Zhang D, Wang F, Vlodavsky I, Hussein B, Rodrigues B, Cardiomyocyte VEGF regulates endothelial cell GPIHBP1 to relocate lipoprotein lipase to the coronary lumen during diabetes mellitus. Arterioscler Thromb Vasc Biol 2016 36 145 155. doi: 10.1161/ATVBAHA.115.306774
16. Hu W, Zhang Y, Wang L, Lau CW, Xu J, Luo JY, Gou L, Yao X, Chen ZY, Ma RC, Tian XY, Huang Y, Bone morphogenic protein 4-Smad-induced upregulation of platelet-derived growth factor AA impairs endothelial function. Arterioscler Thromb Vasc Biol 2016 36 553 560. doi: 10.1161/ATVBAHA.115.306302
17. Chan XY, Black R, Dickerman K, Federico J, Lévesque M, Mumm J, Gerecht S, Three-dimensional vascular network assembly from diabetic patient-derived induced pluripotent stem cells. Arterioscler Thromb Vasc Biol 2015 35 2677 2685. doi: 10.1161/ATVBAHA.115.306362
18. Yiu KH, Tse HF, Specific role of impaired glucose metabolism and diabetes mellitus in endothelial progenitor cell characteristics and function. Arterioscler Thromb Vasc Biol 2014 34 1136 1143. doi: 10.1161/ATVBAHA.114.302192
19. Recio C, Oguiza A, Lazaro I, Mallavia B, Egido J, Gomez-Guerrero C, Suppressor of cytokine signaling 1-derived peptide inhibits Janus kinase/signal transducers and activators of transcription pathway and improves inflammation and atherosclerosis in diabetic mice. Arterioscler Thromb Vasc Biol 2014 34 1953 1960. doi: 10.1161/ATVBAHA.114.304144
20. Gray SP, Di Marco E, Kennedy K, Chew P, Okabe J, El-Osta A, Calkin AC, Biessen EA, Touyz RM, Cooper ME, Schmidt HH, Jandeleit-Dahm KA, Reactive oxygen species can provide atheroprotection via NOX4-dependent inhibition of inflammation and vascular remodeling. Arterioscler Thromb Vasc Biol 2016 36 295 307. doi: 10.1161/ATVBAHA.115.307012
21. Fulton DJ, Barman SA, Clarity on the isoform-specific roles of NADPH oxidases and NADPH oxidase-4 in atherosclerosis. Arterioscler Thromb Vasc Biol 2016 36 579 581. doi: 10.1161/ATVBAHA.116.307096
22. McLaughlin T, Liu LF, Lamendola C, Shen L, Morton J, Rivas H, Winer D, Tolentino L, Choi O, Zhang H, Hui Yen Chng M, Engleman E, T-cell profile in adipose tissue is associated with insulin resistance and systemic inflammation in humans. Arterioscler Thromb Vasc Biol 2014 34 2637 2643. doi: 10.1161/ATVBAHA.114.304636
23. Matsumoto T, Sasaki N, Yamashita T, Emoto T, Kasahara K, Mizoguchi T, Hayashi T, Yodoi K, Kitano N, Saito T, Yamaguchi T, Hirata K, Overexpression of cytotoxic T-lymphocyte-associated antigen-4 prevents atherosclerosis in mice. Arterioscler Thromb Vasc Biol 2016 36 1141 1151. doi: 10.1161/ATVBAHA.115.306848
24. Harmon DB, Srikakulapu P, Kaplan JL, Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance. Arterioscler Thromb Vasc Biol 2016 36 682 691. doi: 10.1161/ATVBAHA.116.307166
25. Edsfeldt A, Gonçalves I, Grufman H, Nitulescu M, Dunér P, Bengtsson E, Mollet IG, Persson A, Nilsson M, Orho-Melander M, Melander O, Björkbacka H, Nilsson J, Impaired fibrous repair: a possible contributor to atherosclerotic plaque vulnerability in patients with type II diabetes. Arterioscler Thromb Vasc Biol 2014 34 2143 2150. doi: 10.1161/ATVBAHA.114.303414
26. Goncalves I, Bengtsson E, Colhoun HM, SUMMIT Consortium Elevated Plasma levels of MMP-12 are associated with atherosclerotic burden and symptomatic cardiovascular disease in subjects with type 2 diabetes. Arterioscler Thromb Vasc Biol 2015 35 1723 1731. doi: 10.1161/ATVBAHA.115.305631
27. Byrne CD, Targher G, Ectopic fat, insulin resistance, and nonalcoholic fatty liver disease: implications for cardiovascular disease. Arterioscler Thromb Vasc Biol 2014 34 1155 1161. doi: 10.1161/ATVBAHA.114.303034
28. Lim S, Meigs JB, Links between ectopic fat and vascular disease in humans. Arterioscler Thromb Vasc Biol 2014 34 1820 1826. doi: 10.1161/ATVBAHA.114.303035
29. Miller M, Stone NJ, Ballantyne C, Bittner V, Criqui MH, Ginsberg HN, Goldberg AC, Howard WJ, Jacobson MS, Kris-Etherton PM, Lennie TA, Levi M, Mazzone T, Pennathur S, American Heart Association Clinical Lipidology, Thrombosis, and Prevention Committee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular Nursing; Council on the Kidney in Cardiovascular Disease Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association. Circulation 2011 123 2292 2333. doi: 10.1161/CIR.0b013e3182160726
30. Willecke F, Scerbo D, Nagareddy P, Obunike JC, Barrett TJ, Abdillahi ML, Trent CM, Huggins LA, Fisher EA, Drosatos K, Goldberg IJ, Lipolysis, and not hepatic lipogenesis, is the primary modulator of triglyceride levels in streptozotocin-induced diabetic mice. Arterioscler Thromb Vasc Biol 2015 35 102 110. doi: 10.1161/ATVBAHA.114.304615
31. Miao J, Manthena PV, Haas ME, Ling AV, Shin DJ, Graham MJ, Crooke RM, Liu J, Biddinger SB, Role of insulin in the regulation of proprotein convertase Subtilisin/Kexin Type 9. Arterioscler Thromb Vasc Biol 2015 35 1589 1596. doi: 10.1161/ATVBAHA.115.305688
32. Li WW, Dammerman MM, Smith JD, Metzger S, Breslow JL, Leff T, Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia. J Clin Invest 1995 96 2601 2605. doi: 10.1172/JCI118324
33. Qamar A, Khetarpal SA, Khera AV, Qasim A, Rader DJ, Reilly MP, Plasma apolipoprotein C-III levels, triglycerides, and coronary artery calcification in type 2 diabetics. Arterioscler Thromb Vasc Biol 2015 35 1880 1888. doi: 10.1161/ATVBAHA.115.305415
34. Rosenson R, The high-density lipoprotein puzzle: why classic epidemiology, genetic epidemiology, and clinical trials conflict? Arterioscler Thromb Vasc Biol 2016 36 777 782. doi: 10.1161/ATVBAHA.116.307024
35. Khera AV, Cuchel M, de la Llera-Moya M, Rodrigues A, Burke MF, Jafri K, French BC, Phillips JA, Mucksavage ML, Wilensky RL, Mohler ER, Rothblat GH, Rader DJ, Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis. N Engl J Med 2011 364 127 135. doi: 10.1056/NEJMoa1001689
36. Rohatgi A, Khera A, Berry JD, Givens EG, Ayers CR, Wedin KE, Neeland IJ, Yuhanna IS, Rader DR, de Lemos JA, Shaul PW, HDL cholesterol efflux capacity and incident cardiovascular events. N Engl J Med 2014 371 2383 2393. doi: 10.1056/NEJMoa1409065
37. Barter PJ, Rye KA, Tardif JC, Waters DD, Boekholdt SM, Breazna A, Kastelein JJ, Effect of torcetrapib on glucose, insulin, and hemoglobin A1c in subjects in the Investigation of Lipid Level Management to Understand its Impact in Atherosclerotic Events (ILLUMINATE) trial. Circulation 2011 124 555 562. doi: 10.1161/CIRCULATIONAHA.111.018259
38. Cochran BJ, Bisoendial RJ, Hou L, Glaros EN, Rossy J, Thomas SR, Barter PJ, Rye KA, Apolipoprotein A-I increases insulin secretion and production from pancreatic β-cells via a G-protein-cAMP-PKA-FoxO1-dependent mechanism. Arterioscler Thromb Vasc Biol 2014 34 2261 2267. doi: 10.1161/ATVBAHA.114.304131
39. Rosenson RS, Brewer HB Jr, Ansell BJ, Barter P, Chapman MJ, Heinecke JW, Kontush A, Tall AR, Webb NR, Dysfunctional HDL and atherosclerotic cardiovascular disease. Nat Rev Cardiol 2016 13 48 60. doi: 10.1038/nrcardio.2015.124
40. Apro J, Tietge UJ, Dikkers A, Parini P, Angelin B, Rudling M, Impaired cholesterol efflux capacity of high-density lipoprotein isolated from interstitial fluid in type 2 diabetes mellitus. Arterioscler Thromb Vasc Biol 2016 36 787 791. doi: 10.1161/ATVBAHA.116.307385
41. Brinck JW, Thomas A, Lauer E, Diabetes mellitus is associated with reduced high-density lipoprotein sphingosine-1-phosphate content and impaired high-density lipoprotein cardiac cell protection. Arterioscler Thromb Vasc Biol 2016 36 817 824. doi: 10.1161/ATVBAHA.115.307049
42. Edsfeldt A, Duner P, Stahlman M, Mollet IG, Asciutto G, Grufman H, Nitulescu M, Persson AF, Fisher RM, Melander O, Melander O, Boren J, Nilsson J, Gonçalves I, Sphingolipids contribute to human atherosclerotic plaque inflammation. Arterioscler Thromb Vasc Biol 2016 36 1132 1140. doi: 10.1161/ATVBAHA.116.305675