Bone morphogenic protein 4-smad-induced upregulation of platelet-derived growth Factor AA impairs endothelial function

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 3, 2016, Pages 553-560

  Hu, Weining ^a   Zhang, Yang ^a   Wang, Li ^a   Lau, Chi Wai ^a   Xu, Jian ^a   Luo, Jiang Yun ^a   Gou, Lingshan ^a   Yao, Xiaoqiang ^a   Chen, Zhen Yu ^b   Ma, Ronald Ching Wan ^c   Tian, Xiao Yu ^a   Huang, Yu ^a  

^a The Chinese Medicine Division   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

diabetes mellitus; endothelial dysfunction; platelet derived growth factor; vascular reactivity

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR BB; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; SMAD PROTEIN; SMAD1 PROTEIN; SMAD4 PROTEIN; SMAD5 PROTEIN; BMP4 PROTEIN, HUMAN; BMP4 PROTEIN, MOUSE; NEUTRALIZING ANTIBODY; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET-DERIVED GROWTH FACTOR A; RECEPTOR REGULATED SMAD PROTEIN; VASODILATOR AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; AORTA; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DIABETES MELLITUS; ENDOTHELIAL DYSFUNCTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; UPREGULATION; VASODILATATION; ADULT; AGED; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CASE CONTROL STUDY; CELL CULTURE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; ENDOTHELIUM CELL; GENETIC TRANSFECTION; GENETICS; MALE; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTOR; TISSUE CULTURE TECHNIQUE; VASCULAR ENDOTHELIUM;

ADULT; AGED; ANIMALS; ANTIBODIES, NEUTRALIZING; BONE MORPHOGENETIC PROTEIN 4; CASE-CONTROL STUDIES; CELLS, CULTURED; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; PLATELET-DERIVED GROWTH FACTOR; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMAD PROTEINS, RECEPTOR-REGULATED; TIME FACTORS; TISSUE CULTURE TECHNIQUES; TRANSFECTION; UP-REGULATION; VASODILATION; VASODILATOR AGENTS;

EID: 84959467600     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.306302     Document Type: Article

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