Glutathione S-transferase pi expression regulates the Nrf2-dependent response to hormetic diselenides

Free Radical Biology and Medicine

Volumn 88, Issue Part B, 2015, Pages 466-480

  Bartolini, D ^a   Commodi, J ^a   Piroddi, M ^a   Incipini, L ^a   Sancineto, L ^a   Santi, C ^a   Galli, F ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Diselenides; Glutathione peroxidase; Glutathione S transferase pi; Hormesis; Nrf2; Phase II genes; Seleno organic compounds; Thiols

Indexed keywords

BENZOIC ACID DERIVATIVE; CYTOCHROME C; DIPHENYL DISELENIDE; ESTER DERIVATIVE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE P1; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OLIGOMER; THIOL; THIOL DERIVATIVE; TRANSCRIPTION FACTOR NRF2; ORGANOSELENIUM DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL SURVIVAL; CELL VIABILITY; CELL VIABILITY ASSAY; CLONOGENIC ASSAY; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY ASSAY; EMBRYO; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEPG2 CELL LINE; HORMESIS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; KNOCKOUT GENE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; FIBROBLAST; GENE INACTIVATION; IMMUNOBLOTTING; METABOLISM; OXIDATIVE STRESS;

ANIMALS; FIBROBLASTS; GENE KNOCKOUT TECHNIQUES; GLUTATHIONE S-TRANSFERASE PI; HEP G2 CELLS; HORMESIS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICE; NF-E2-RELATED FACTOR 2; ORGANOSELENIUM COMPOUNDS; OXIDATIVE STRESS;

EID: 84970968586     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.06.039     Document Type: Article

References (34)

1. V. Calabrese, C. Cornelius, A.T. Dinkova-Kostova, I. Iavicoli, R. Di Paola, A. Koverech, S. Cuzzocrea, E. Rizzarelli, and E.J. Calabrese Cellular stress responses, hormetic phytochemicals, and vitagenes in aging and longevity Biochim. Biophys. Acta. 1822 2012 753 783
2. M. Hormetics Birringer Dietary triggers of an adaptive stress response Pharm. Res. 28 2011 2680 2694
3. M. McMahon, D.J. Lamont, K.A. Beattie, and J.D. Hayes Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals Proc. Natl. Acad. Sci. USA 107 2010 18838 18843
4. Y.J. Surh, J.K. Kundu, and H.K. Na Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals Planta Med. 74 2008 1526 1539
5. S.K. Niture, R. Khatri, and A.K. Jaiswal Regulation of Nrf2: An update Free Radic. Biol. Med. 66 2014 36 44
6. C.J. Harvey, R.K. Thimmulappa, A. Singh, D.J. Blake, G. Ling, N. Wakabayashi, J. Fujii, A. Myers, and S. Biswal Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress Free Radic. Biol. Med. 46 2009 443 453
7. K. Taguchi, H. Motohashi, and M. Yamamoto Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution Genes Cells 16 2011 123 140
8. T.G. Son, S. Camandola, and M.P. Mattson Hormetic dietary phytochemicals Neuromol. Med. 10 2008 236 246
9. C. Santi, C. Tidei, C. Scalera, M. Piroddi, and F. Galli Selenium containing compounds from poison to drug candidates: A review on the GPx-like activity Curr. Chem. Biol. 7 2013 25 36
10. L. Orian, and S. Toppo Organochalcogen peroxidase mimetics as potential drugs: A long story of a promise still unfulfilled Free Radic. Biol. Med. 66 2014 65 74
11. D. Bartolini, M. Piroddi, C. Tidei, S. Giovagnoli, D. Pietrella, Y. Manevich, K.D. Tew, D. Giustarini, R. Rossi, D.M. Townsend, C. Santi, and F. Galli Reaction kinetics and targeting to cellular glutathione S-transferase of the glutathione peroxidase mimetic PhSeZnCl and its d,l-polylactide microparticle formulation Free Radic. Biol. Med. 78 2015 56 65
12. C. Tidei, M. Piroddi, F. Galli, and C. Santi Oxidation of thiols promoted by PhSeZnCl Tetrahedron Lett. 53 2012 232 234
13. M.I. Jackson, and G.F. Combs Jr. Selenium and anticarcinogenesis: Underlying mechanisms Curr. Opin. Clin. Nutr. Metab. Care 11 2008 718 726
14. L. Yan, and J.E. Spallholz Generation of reactive oxygen species from the reaction of selenium compounds with thiols and mammary tumor cells Biochem. Pharmacol. 45 1993 429 437
15. M.J. Parnham, and H. Sies The early research and development of Ebselen Biochem. Pharmacol. 86 2013 1248 1253
16. C.W. Nogueira, G. Zeni, and J.B.T. Rocha Organoselenium and organotellurium compounds: Toxicology and pharmacology Chem. Rev. 104 2004 6255 6286
17. H. Xiao, and K.L. Parkin Induction of phase II enzyme activity by various selenium compounds Nutr. Cancer 55 2006 210 223
18. Y. Manevich, S. Hutchens, K.D. Tew, and D.M. Townsend Allelic variants of glutathione S-transferase P1-1 differentially mediate the peroxidase function of peroxiredoxin VI and alter membrane lipid peroxidation Free Radic. Biol. Med. 54 2013 62 70
19. K.D. Tew, Y. Manevich, C. Grek, Y. Xiong, J. Uys, and D.M. Townsend The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer Free Radic. Biol. Med. 51 2011 299 313
20. K.D. Tew, and D.M. Townsend Regulatory functions of glutathione S-transferase P1-1 unrelated to detoxification Drug Metab. Rev. 43 2011 179 193
21. O. Vasieva The many faces of glutathione transferase pi Curr. Mol. Med. 11 2011 129 139
22. C. Santi, F. Galli, M. Piroddi, and C. Tidei Thiols oxidation for the evaluation of GPX-like activity Phosphorus Sulfur Silicon 188 2013 507 508
23. W. Li, S.W. Yu, and A.N. Kong Nrf2 possesses a redox-sensitive nuclear exporting signal in the Neh5 transactivation domain J. Biol. Chem. 281 2006 27251 27263
24. F. Galli Interactions of polyphenolic compounds with drug disposition and metabolism Curr. Drug Metab. 8 2007 830 838
25. J.K. Kundu, and Y.J. Surh Inflammation: Gearing the journey to cancer Mutat. Res. 659 2008 15 30
26. V. Nascimento, N.L. Ferreira, R.F.S. Canto, K.L. Schott, E.P. Waczuk, L. Sancineto, C. Santi, J.B.T. Rocha, and A.L. Braga Synthesis and biological evaluation of new nitrogen-containing diselenides Eur. J. Med. Chem. 87 2014 131 139
27. T. Mosmann Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays J. Immunol. Methods 65 1983 55 63
28. A. Wendel Glutathione peroxidase Methods Enzymol. 77 1981 325 333
29. S.K. Ahn, S. Hong, Y.M. Park, W.T. Lee, K.A. Park, and J.E. Lee Effects of agmatine on hypoxic microglia and activity of nitric oxide synthase Brain Res. 1373 2011 48 54
30. J.M. Walker The bicinchoninic acid (BCA) assay for protein quantitation Methods Mol. Biol. 32 1994 5 8
31. 2-induced block of glycolysis as an active ADP-ribosylation reaction protecting cells from apoptosis FASEB J. 14 2000 2266 2276
32. F. Luchetti, M. Betti, B. Canonico, M. Arcangeletti, P. Ferri, F. Galli, and S. Papa ERK MAPK activation mediates the antiapoptotic signaling of melatonin in UVB-stressed U937 cells Free Radic. Biol. Med. 46 2009 339 351
33. M. Betti, A. Minelli, B. Canonico, P. Castaldo, S. Magi, M.C. Aisa, M. Piroddi, V. Di Tomaso, and F. Galli Antiproliferative effects of tocopherols (vitamin E) on murine glioma C6 cells: Homologue-specific control of PKC/ERK and cyclin signaling Free Radic. Biol. Med. 41 2006 464 472
34. D.M. Townsend, Y. Manevich, L. He, S. Hutchens, C.J. Pazoles, and K.D. Tew Novel role for glutathione S-transferase pi: Regulator of protein S-glutathionylation following oxidative and nitrosative stress J. Biol. Chem. 284 2009 436 445