Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance

Nature

Volumn 533, Issue 7601, 2016, Pages 58-63

  Badran, Ahmed H ^a,b   Guzov, Victor M ^c   Huai, Qing ^c   Kemp, Melissa M ^c   Vishwanath, Prashanth ^c   Kain, Wendy ^d   Nance, Autumn M ^c   Evdokimov, Artem ^c,e   Moshiri, Farhad ^c   Turner, Keith H ^c   Wang, Ping ^d   Malvar, Thomas ^c   Liu, David R ^a,b  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c MONSANTO COMPANY   (United States)

^d Department of Obstetrics Gynecology   (United States)

^e HarkerBIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; CRY1AC TOXIN; BACTERIAL PROTEIN; ENDOTOXIN; HEMOLYSIN; INSECTICIDAL CRYSTAL PROTEIN, BACILLUS THURINGIENSIS; INSECTICIDE; PROTEIN BINDING;

ARTICLE; BACILLUS THURINGIENSIS; BINDING AFFINITY; CONTROLLED STUDY; DISSOCIATION CONSTANT; DNA SEQUENCE; INSECT RESISTANCE; INSECTICIDAL ACTIVITY; MOLECULAR EVOLUTION; MUTAGENESIS; NONHUMAN; PHAGE ASSISTED CONTINUOUS EVOLUTION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RECEPTOR AFFINITY; RECEPTOR BINDING; TRANSCRIPTION INITIATION; TRICHOPLUSIA NI; AMINO ACID SEQUENCE; ANIMAL; BACTERIOPHAGE; BIOLOGICAL PEST CONTROL; BIOTECHNOLOGY; CELL DEATH; CONSENSUS SEQUENCE; CROP; CYTOLOGY; DIRECTED MOLECULAR EVOLUTION; GENETIC SELECTION; GENETIC VARIATION; GENETICS; INSECTICIDE RESISTANCE; METABOLISM; MOLECULAR GENETICS; MOTH; PHYSIOLOGY; PROCEDURES; TRANSGENIC PLANT;

AMINO ACID SEQUENCE; ANIMALS; BACILLUS THURINGIENSIS; BACTERIAL PROTEINS; BACTERIOPHAGES; BIOTECHNOLOGY; CADHERINS; CELL DEATH; CONSENSUS SEQUENCE; CROPS, AGRICULTURAL; DIRECTED MOLECULAR EVOLUTION; ENDOTOXINS; GENETIC VARIATION; HEMOLYSIN PROTEINS; INSECTICIDE RESISTANCE; INSECTICIDES; MOLECULAR SEQUENCE DATA; MOTHS; MUTAGENESIS; PEST CONTROL, BIOLOGICAL; PLANTS, GENETICALLY MODIFIED; PROTEIN BINDING; PROTEIN STABILITY; SELECTION, GENETIC;

EID: 84969786561     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature17938     Document Type: Article

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