Development of potent in vivo mutagenesis plasmids with broad mutational spectra

Nature Communications

Volumn 6, Issue , 2015, Pages

  Badran, Ahmed H ^a,b   Liu, David R ^a,b  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL MUTAGEN; RNA POLYMERASE; BACTERIOPHAGE T7 RNA POLYMERASE; DNA DIRECTED RNA POLYMERASE; ESCHERICHIA COLI PROTEIN; RPOB PROTEIN, E COLI; VIRAL PROTEIN;

CELLS AND CELL COMPONENTS; CHEMICAL SUBSTANCE; CHROMOSOME; ENZYME ACTIVITY; EXPERIMENTAL STUDY; LABORATORY METHOD; MICROBIAL ACTIVITY; MUTAGENICITY; MUTATION; PLASMID; STRATEGIC APPROACH; ULTRAVIOLET RADIATION; VIRUS;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL MUTATION; BACTERIOPHAGE; CHROMOSOME; CONTROLLED STUDY; DEAMINATION; DNA METHYLATION; EPISOME; ESCHERICHIA COLI; EXCISION REPAIR; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR EVOLUTION; MUTAGENESIS; MUTATION RATE; MUTATIONAL ANALYSIS; NONHUMAN; PLASMID; ULTRAVIOLET RADIATION; ENTEROBACTERIA PHAGE T3; GENE VECTOR; GENETIC ENGINEERING; GENETIC PROCEDURES; GENETICS; HIGH THROUGHPUT SEQUENCING; LACTOSE OPERON; MUTATION; PROCEDURES; PROMOTER REGION;

BACTERIA (MICROORGANISMS);

BACTERIOPHAGE T3; DNA-DIRECTED RNA POLYMERASES; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENETIC ENGINEERING; GENETIC TECHNIQUES; GENETIC VECTORS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; LAC OPERON; MUTAGENESIS; MUTATION; PLASMIDS; PROMOTER REGIONS, GENETIC; VIRAL PROTEINS;

EID: 84943777049     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9425     Document Type: Article

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