Active tumor permeation and uptake of surface charge-switchable theranostic nanoparticles for imaging-guided photothermal/chemo combinatorial therapy

Theranostics

Volumn 6, Issue 3, 2016, Pages 302-317

  Hung, Chia Chian ^a   Huang, Wen Chia ^a   Lin, Yi Wen ^a   Yu, Ting Wei ^a   Chen, Hsin Hung ^b   Lin, Sung Chyr ^b   Chiang, Wen Hsuan ^a   Chiu, Hsin Cheng ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Chemotherapy; Deep tumor penetration; Photothermal therapy; Surface charge transition; Tumor hypoxia

Indexed keywords

ALPHA TOCOPHEROL; DOXORUBICIN; INDOCYANINE GREEN; MACROGOL; N ACETYLHISTIDINE; N ACETYLHISTIDINE MODIFIED DEXTRO ALPHA TOCOPHERYL POLYETHYLENE GLYCOL SUCCINATE; NANOCARRIER; NANOPARTICLE; POLYGLACTIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DRUG CARRIER; MACROGOL DERIVATIVE; PHOTOSENSITIZING AGENT; POLY(LACTIDE)-TOCOPHERYL POLYETHYLENE GLYCOL SUCCINATE; SUCCINIC ACID DERIVATIVE;

ACIDITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CANCER SIZE; CANCER THERAPY; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG MECHANISM; DRUG PENETRATION; DRUG RELEASE; DRUG TUMOR LEVEL; EX VIVO STUDY; EXTRACELLULAR MATRIX; HYDROPHOBICITY; HYPOXIA; IMAGING GUIDED PHOTOTHERMAL THERAPY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PH; PROSTATE CANCER; PROTON TRANSPORT; SOLID TUMOR; SUBCUTANEOUS TISSUE TUMOR; SURFACE PROPERTY; THERMOTHERAPY; TISSUE SECTION; ANIMAL; C57BL MOUSE; DISEASE MODEL; DRUG THERAPY; INTRAVENOUS DRUG ADMINISTRATION; MULTIMODALITY CANCER THERAPY; PHOTOTHERAPY; PROCEDURES; SKIN NEOPLASMS; THERANOSTIC NANOMEDICINE; TISSUE DISTRIBUTION;

ADMINISTRATION, INTRAVENOUS; ANIMALS; ANTINEOPLASTIC AGENTS; COMBINED MODALITY THERAPY; DISEASE MODELS, ANIMAL; DOXORUBICIN; DRUG CARRIERS; DRUG THERAPY; HYPERTHERMIA, INDUCED; INDOCYANINE GREEN; MALE; MICE, INBRED C57BL; NANOPARTICLES; PHOTOSENSITIZING AGENTS; PHOTOTHERAPY; POLYETHYLENE GLYCOLS; SKIN NEOPLASMS; SUCCINATES; THERANOSTIC NANOMEDICINE; TISSUE DISTRIBUTION;

EID: 84969754369     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.13686     Document Type: Article

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