Dual-layered nanogel-coated hollow lipid/polypeptide conjugate assemblies for potential pH-triggered intracellular drug release

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Chiang, Wen Hsuan ^a   Huang, Wen Chia ^a   Shen, Ming Yin ^a,b   Wang, Che Hsu ^a   Huang, Yi Fong ^c   Lin, Sung Chyr ^c   Chern, Chorng Shyan ^d   Chiu, Hsin Cheng ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHITOSAN; DOXORUBICIN; GLUTAMIC ACID; LIPID; MACROGOL; POLYPEPTIDE; MACROGOL DERIVATIVE; MONOMETHOXYPOLYETHYLENE GLYCOL; NANOGEL; PEPTIDE; POLY(GAMMA-GLUTAMIC ACID); POLYETHYLENEIMINE; POLYGLUTAMIC ACID;

ARTICLE; CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG STRUCTURE; ENDOCYTOSIS; ENDOSOME; GEL; HELA CELL LINE; IN VITRO STUDY; LYSOSOME; PH; PROTON TRANSPORT; ANALOGS AND DERIVATIVES; CELL DEATH; CHEMISTRY; DRUG EFFECTS; FLOW CYTOMETRY; HUMAN; INTRACELLULAR SPACE; LIGHT; METABOLISM; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RADIATION SCATTERING; STATIC ELECTRICITY; SYNTHESIS;

CELL DEATH; CHITOSAN; DOXORUBICIN; DRUG LIBERATION; ENDOCYTOSIS; FLOW CYTOMETRY; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR SPACE; LIGHT; LIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR WEIGHT; PEPTIDES; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; POLYGLUTAMIC ACID; SCATTERING, RADIATION; STATIC ELECTRICITY;

EID: 84902310528     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092268     Document Type: Article

References (43)

1. Samad A, Sultana Y, Aqil M (2007) Liposomal drug delivery systems: an update review. Curr Drug Deliv 4: 297-305. (Pubitemid 47554274)
2. Elbayoumi TA, Torchilin VP (2010) Current trends in liposome research. Methods Mol Biol 605: 1-27.
3. Park JH, Lee S, Kim JH, Park K, Kim K, et al. (2008) Polymeric nanomedicine for cancer therapy. Prog Polym Sci 33: 113-137. (Pubitemid 350278530)
4. Miyata K, Christie RJ, Kataoka K (2011) Polymeric micelles for nano-scale drug delivery. React Funct Polym 71: 227-234.
5. Broz P, Driamov S, Ziegler J, Ben-Haim N, Marsch S, et al. (2006) Toward intelligent nanosize bioreactors: a pH-switchable, channel-equipped, functional polymer nanocontainer. Nano Lett 6: 2349-2353 (Pubitemid 44663830)
6. Blanazs A, Armes SP, Ryan AJ (2009) Self-assembled block copolymer aggregates: from micelles to vesicles and their biological applications. Macromol Rapid Commun 30: 267-277.
7. Wang W, Cheng D, Gong F, Miao X, Shuai X (2012) Design of multifunctional micelle for tumor-targeted intracellular drug release and fluorescent imaging. Adv Mater 24: 115-120.
8. Rapoport N (2007) Physical stimuli-responsive polymeric micelles for anti-cancer drug delivery. Prog Polym Sci 32: 962-990.
9. Sun Q, Cheng D, Yu X, Zhang Z, Dai J, et al. (2011) A pH-sensitive polymeric nanovesicle based on biodegradable poly(ethylene glycol)-b-poly(2- (diisopropylamino)ethyl aspartate) as a MRI-visible drug delivery system. J Mater Chem 21: 15316-15326.
10. Chiang WH, Ho VT, Huang WC, Huang YF, Chern CS, et al. (2012) Dual stimuli-responsive polymeric hollow nanogels designed as carriers for intracellular triggered drug release. Langmuir 28: 15056-15064.
11. Al-Ahmady ZS, Al-Jamal WT, Bossche JV, Bui TT, Drake AF, et al. (2012) Lipid-peptide vesicle nanoscale hybrids for triggered drug release by mild hyperthermia in vitro and in vivo. ACS Nano 6: 9335-9346.
12. Du JZ, Du XJ, Mao CQ, Wang J (2011) Tailor-made dual pH-sensitive polymer-doxorubicin nanoparticles for efficient anticancer drug delivery. J Am Chem Soc 133: 17560-17563.
13. Chiu HC, Lin YW, Huang YF, Chuang CK, Chern CS (2008) Polymer vesicles containing small vesicles within interior aqueous compartments and pH-responsive transmembrane channels. Angew Chem Int Ed 47:1875-1878.
14. Zheng C, Yao X, Qiu L (2011) Novel polymeric vesicles with pH-induced deformation character for advanced drug delivery. Macromol Biosci 11: 338-343.
15. Huang YF, Chiang WH, Tsai PL, Chern CS, Chiu HC (2011) Novel hybrid vesicles co-assembled from a cationic lipid and PAAc-g-mPEG with pH-triggered transmembrane channels for controlled drug release. Chem Commun 47: 10978-10980.
16. Sun P, Zhou D, Gan Z (2011) Novel reduction-sensitive micelles for triggered intracellular drug release. J Control Release 155: 96-103.
17. Li J, Huo M, Wang J, Zhou J, Mohammad JM, et al. (2012) Redox-sensitive micelles self-assembled from amphiphilic hyaluronic acid-deoxycholic acid conjugates for targeted intracellular delivery of paclitaxel. Biomaterials 33: 2310-2320.
18. Zhang L, Xue H, Cao Z, Keefe A, Wang J, et al (2011) Multifunctional and degradable zwitterionic nanogels for targeted delivery, enhanced MR imaging, reduction-sensitive drug release, and renal clearance. Biomaterials 32: 4604-4608.
19. Chiang WH, Hsu YH, Lou TW, Chern CS, Chiu HC (2009) Effects of mPEG grafts on morphology and cross-linking of thermally induced micellar assemblies from PAAc-based graft copolymers in aqueous phase. Macromolecules 42: 3611-3619.
20. Dai J, Lin S, Cheng D, Zou S, Shuai X (2011) Interlayer-crosslinked micelle with partially hydrated core showing reduction and pH dual sensitivity for pinpointed intracellular drug release. Angew Chem Int Ed 50: 9404-9408.
21. Li YL, Zhu L, Liu Z, Cheng R, Meng F, et al. (2009) Reversibly stabilized multifunctional dextran nanoparticles efficiently deliver doxorubicin into the nuclei of cancer cells. Angew Chem Int Ed 48: 9914-9918.
22. Lee HJ, Kim SE, Kwon IK, Park C, Kim C, et al. (2010) Spatially mineralized self-assembled polymeric nanocarriers with enhanced robustness and controlled drug-releasing property. Chem Commun 46: 377-379.
23. Han SY, Han HS, Lee SC, Kang YM, Kim IS, et al. (2011) Mineralized hyaluronic acid nanoparticles as a robust drug carrier. J. Mater. Chem. 21: 7996-8001.
24. Chen Z, Li Z, Lin Y, Yin M, Ren J, et al. (2013) Biomineralization inspired surface engineering of nanocarriers for pH-responsive, targeted drug delivery. Biomaterials 34: 1364-1371.
25. Lee SM, Song Y, Hong BJ, MacRenaris KW, Mastarone DJ, et al. (2010) Modular polymer-caged nanobins as a theranostic platform with enhanced magnetic resonance relaxivity and pH-responsive drug release. Angew Chem Int Ed 49: 9960-9964.
26. Ning S, Huang Q, Sun X, Li C, Zhang Y, et al. (2011) Carboxymethyl dextran-coated liposomes: Toward a robust drug delivery platform. Soft Matter 7: 9394-9401.
27. Lee SM, Chen H, O'Halloran TV, Nguyen ST (2009) "Clickable" polymer-caged nanobins as a modular drug delivery platform. J Am Chem Soc 131: 9311-9320.
28. Hsu YH, Chiang WH, Chen CH, Chern CS, Chiu HC (2005) Thermally responsive interactions between the PEG and PNIPAAm grafts attached to the PAAc backbone and the corresponding structural changes of polymeric micelles in water. Macromolecules 38: 9757-9765. (Pubitemid 41698429)
29. Hsu YH, Chiang WH, Chen MC, Chern CS, Chiu HC (2006) Effects of SDS on the thermo- and pH-sensitive structural changes of the poly(acrylic acid)-based copolymer containing both poly(N-isopropylacrylamide) and monomethoxy poly(ethylene glycol) grafts in water. Langmuir 22: 6764-6770.
30. Smith AE, Xu X, Kirkland-York SE, Savin DA, McCormick CL (2010)"Schizo-"Schizophrenic" self-assembly of block copolymers synthesized via aqueous RAFT polymerization: from micelles to vesicles. Macromolecules 43: 1210-1217.
31. Dou HJ, Jiang M, Peng HS, Chen DY, Hong Y (2003) pH-Dependent self-assembly: micellization and micelle-hollow-sphere transition of cellulose-based copolymers. Angew Chem Int Ed 42: 1516-1519. (Pubitemid 36458513)
32. Wan WM, Sun XL, Pan CY (2009) Morphology transition in RAFT polymerization for formation of vesicular morphologies in one pot. Macromolecules 42: 4950-4952.
33. 2+-ion-manipulated, size-selective permeability. Adv Funct Mater 22: 2267-2275.
34. Manocha B, Margaritis A (2010) Controlled release of doxorubicin from doxorubicin/γ-polyglutamic acid ionic complex J Nanomater 2010: 1-9.
35. Bae HH, Cho MY, Hong JH, Poo H, Sung MH, et al. (2012) Bio-derived poly(gamma-glutamic acid) nanogels as controlled anticancer drug delivery carriers. J Microbiol Biotechnol 22: 1782-1789.
36. Poon Z, Chang D, Zhao X, Hammond PT (2011) Layer-by-layer nanoparticles with a pH-sheddable layer for in vivo targeting of tumor hypoxia. ACS Nano 5: 4284-4292.
37. Cuomo F, Lopez F, Miguel MG, Lindman B (2010) Vesicle-templated layer-by-layer assembly for the production of nanocapsules. Langmuir 26: 10555-10560.
38. Shuai X, Ai H, Nasongkla N, Kim S, Gao J (2004) Micellar carriers based on block copolymers of poly(epsilon-caprolactone) and poly(ethylene glycol) for doxorubicin delivery. J Control Release 98: 415-426. (Pubitemid 39093952)
39. Osaka T, Nakanishi T, Shanmugam S, Takahama S, Zhang H (2009) Effect of surface charge of magnetite nanoparticles on their internalization into breast cancer and umbilical vein endothelial cells. Colloid Surfaces B 71: 325-330.
40. Jung SH, Jung SH, Seong H, Cho SH, Jeong KS, et al. (2009) Polyethylene glycol-complexed cationic liposome for enhanced cellular uptake and anticancer activity. Int J Pharm 382: 254-261.
41. Wang D, Su Y, Jin C, Zhu B, Pang Y, et al. (2011) Supramolecular copolymer micelles based on the complementary multiple hydrogen bonds of nucleobases for drug delivery. Biomacromolecules 12: 1370-1379.
42. Zhang WL, Li YL, Liu LX, Sun QQ, Shuai XT, et al. (2010) Amphiphilic toothbrushlike copolymers based on poly(ethylene glycol) and poly(epsilon-caprolactone) as drug carriers with enhanced properties. Biomacromolecules 11: 1331-1338.
43. Tang R, Ji W, Panus D, Palumbo RN, Wang C (2011) Block copolymer micelles with acid-labile ortho ester side-chains: Synthesis, characterization, and enhanced drug delivery to human glioma cells. J Control Release 151: 18-27.