A tumor-acidity-activated charge-conversional nanogel as an intelligent vehicle for promoted tumoral-cell uptake and drug delivery

Angewandte Chemie - International Edition

Volumn 49, Issue 21, 2010, Pages 3621-3626

  Du, Jin Zhi ^a   Sun, Tian Meng ^b   Song, Wen Jing ^b   Wu, Juan ^a   Wang, Jun ^b  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Antitumor agents; Charge conversion; Drug delivery; Nanoparticles; PH responsive

Indexed keywords

ANTI-TUMOR AGENTS; CELL UPTAKE; DRUG DELIVERY NANOPARTICLE; DRUG RELEASE; IN-VITRO; INTELLIGENT VEHICLES; NANOGELS; PH-RESPONSIVE; PHYSIOLOGICAL PH; POSITIVELY CHARGED; PROTONATED STATE; TUMOR CELLS; TUMOR EXTRACELLULAR PH;

DRUG DELIVERY; ENZYME ACTIVITY; INTELLIGENT VEHICLE HIGHWAY SYSTEMS; NANOPARTICLES; NANOSTRUCTURED MATERIALS; PH EFFECTS; TUMORS;

DRUG INTERACTIONS;

2,3-DIMETHYLMALEIC ANHYDRIDE; ANTINEOPLASTIC AGENT; DIMETHYLMALEIC ACID ANHYDRIDE; MALEIC ANHYDRIDE; NANOPARTICLE; POLY(ACRYLATE METHACRYLATE); POLY(ACRYLIC ACID-CO-METHACRYLIC ACID); POLYMETHACRYLIC ACID DERIVATIVE;

ARTICLE; ATOMIC FORCE MICROSCOPY; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DELIVERY SYSTEM; GEL; PH;

ANTINEOPLASTIC AGENTS; DRUG DELIVERY SYSTEMS; GELS; HYDROGEN-ION CONCENTRATION; MALEIC ANHYDRIDES; MICROSCOPY, ATOMIC FORCE; MOLECULAR STRUCTURE; NANOPARTICLES; POLYMETHACRYLIC ACIDS;

EID: 77952390124     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.200907210     Document Type: Article

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