Monocytic delivery of therapeutic oxygen bubbles for dual-modality treatment of tumor hypoxia

Journal of Controlled Release

Volumn 220, Issue , 2015, Pages 738-750

  Huang, Wen Chia ^a   Shen, Ming Yin ^a,b   Chen, Hsin Hung ^c   Lin, Sung Chyr ^c   Chiang, Wen Hsuan ^a   Wu, Pei Hsuan ^a   Chang, Chien Wen ^a   Chiang, Chi Shiun ^a   Chiu, Hsin Cheng ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Bone marrow derived monocytes; Dual modality therapy, photodynamic magnetothermal combinational therapy; Oxygen therapeutic co delivery; Tumor hypoxia

Indexed keywords

AMPHIBIOUS VEHICLES; BODY FLUIDS; BONE; CELL DEATH; HYPERTHERMIA THERAPY; MAGNETIC LEVITATION VEHICLES; OXYGEN; OXYGEN SUPPLY; PHOTOSENSITIZERS; TUMORS;

BONE MARROW; CO DELIVERIES; DUAL MODALITY; HIGH-FREQUENCY MAGNETIC FIELD; HISTOLOGICAL EXAMINATION; PHOTODYNAMIC THERAPY (PDT); SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES; TUMOR HYPOXIA;

PHOTODYNAMIC THERAPY;

CHLORIN E6; CITRIC ACID; MICROSPHERE; OXYGEN; PHOTOSENSITIZING AGENT; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; UNCLASSIFIED DRUG; MAGNETITE NANOPARTICLE; PHYTOCHLORIN; PORPHYRIN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL MEMBRANE; CELL SURFACE; CELL TRANSPORT; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; FREEZE DRYING; HYDROPHOBICITY; HYPERTHERMIC THERAPY; HYPOXIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LASER; LIPOPHILICITY; MALE; MEMBRANE STRUCTURE; MICROENCAPSULATION; MONOCYTE; MOUSE; NONHUMAN; ONCOGENESIS AND MALIGNANT TRANSFORMATION; OXYGEN SUPPLY; PARTICLE SIZE; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; RED LIGHT; SCANNING ELECTRON MICROSCOPY; TUMOR HYPOXIA; TUMOR MICROENVIRONMENT; ABLATION THERAPY; ANIMAL; APOPTOSIS; BONE MARROW TRANSPLANTATION; C57BL MOUSE; CELL HYPOXIA; DEVICES; METABOLISM; MICROBUBBLE; PATHOLOGY; PHOTOCHEMOTHERAPY; PROCEDURES; PROSTATIC NEOPLASMS; RAW 264.7 CELL LINE; THERMOTHERAPY; TIME FACTOR; TRANSPLANTATION; TUMOR CELL LINE; TUMOR VOLUME;

ABLATION TECHNIQUES; ANIMALS; APOPTOSIS; BONE MARROW TRANSPLANTATION; CELL HYPOXIA; CELL LINE, TUMOR; HYPERTHERMIA, INDUCED; LASERS; MAGNETITE NANOPARTICLES; MALE; MICE; MICE, INBRED C57BL; MICROBUBBLES; MONOCYTES; OXYGEN; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS; PROSTATIC NEOPLASMS; RAW 264.7 CELLS; TIME FACTORS; TUMOR BURDEN; TUMOR MICROENVIRONMENT;

EID: 84949537945     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.09.016     Document Type: Article

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