A pH-sensitive charge-conversion system for doxorubicin delivery

Acta Biomaterialia

Volumn 9, Issue 8, 2013, Pages 7672-7678

  Guan, Xiuwen ^a,b   Li, Yanhui ^b   Jiao, Zixue ^a   Chen, Jie ^a   Guo, Zhaopei ^a   Tian, Huayu ^a   Chen, Xuesi ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b CHANGCHUN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Charge conversion; Complex; Doxorubicin; PH sensitive; Tumor therapy

Indexed keywords

AMINO ACIDS; COMPUTER AIDED DESIGN; CONTROLLED DRUG DELIVERY; MOLECULAR BIOLOGY; SHIELDING; TARGETED DRUG DELIVERY; TUMORS;

CHARGE CONVERSION; COMPLEX; CONVERSION SYSTEMS; DOXORUBICIN; PH SENSITIVE; PH-SENSITIVE; POLY(ETHYLENIMINE); POSITIVELY CHARGED; SHIELDING SYSTEMS; TUMOR THERAPY;

PH SENSORS;

DOXORUBICIN; POLYETHYLENEIMINE DERIVATIVE; POLYGLUTAMIC ACID; POLYLYSINE; POLYMER; DELAYED RELEASE FORMULATION;

ACIDITY; ARTICLE; CELL NUCLEUS; CYTOTOXICITY; CYTOTOXICITY ASSAY; DRUG DELIVERY SYSTEM; ELECTROSTATIC PRECIPITATION; ENDOCYTOSIS; ENDOSOME; LYSOSOME; MICROENVIRONMENT; PH; PRIORITY JOURNAL; ZETA POTENTIAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DIFFUSION; EXPERIMENTAL NEOPLASM; HELA CELL; HUMAN; MATERIALS TESTING; PATHOLOGY; TREATMENT OUTCOME; ADMINISTRATION AND DOSAGE; HELA CELL LINE; NEOPLASMS, EXPERIMENTAL;

DELAYED-ACTION PREPARATIONS; DIFFUSION; DOXORUBICIN; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MATERIALS TESTING; NEOPLASMS, EXPERIMENTAL; POLYMERS; TREATMENT OUTCOME;

EID: 84891670619     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.04.047     Document Type: Article

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