The pruritus- and TH2-associated cytokine IL-31 promotes growth of sensory nerves

Journal of Allergy and Clinical Immunology

Volumn 138, Issue 2, 2016, Pages 500-508.e24

  Feld, Micha ^a   Garcia, Richard ^b   Buddenkotte, Jörg ^a   Katayama, Shintaro ^c   Lewis, Katherine ^b   Muirhead, Gareth ^d   Hevezi, Peter ^e   Plesser, Kristin ^a   Schrumpf, Holger ^a   Krjutskov, Kaarel ^c   Sergeeva, Olga ^f   Müller, Hans Werner ^f   Tsoka, Sophia ^d   Kere, Juha ^c   Dillon, Stacey R ^b   Steinhoff, Martin ^a,g   Homey, Bernhard ^a  

^a UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^b BRISTOL MYERS SQUIBB   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f HEINRICH HEINE UNIVERSITY   (Germany)

^g UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

atopic dermatitis; cutaneous hyperinnervation; dorsal root ganglia; IL 31; IL 31 receptor ; nerve growth

Indexed keywords

INTERLEUKIN 31; INTERLEUKIN 31 RECEPTOR ALPHA; INTERLEUKIN RECEPTOR; STAT3 PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; IL31 PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASAL GANGLION; CELL DEATH; CONTROLLED STUDY; GENE EXPRESSION; GENE PRODUCT; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL GROWTH; NERVE CELL NETWORK; NERVE ELONGATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PRURITUS; SENSORY NERVE CELL; TH2 CELL; TRANSCRIPTION ELONGATION; TRANSCRIPTION INITIATION; ANIMAL; CLUSTER ANALYSIS; CYTOLOGY; GENE EXPRESSION PROFILING; GENETICS; HUMAN; IMMUNOLOGY; INNERVATION; KNOCKOUT MOUSE; METABOLISM; NERVE FIBER; PHOSPHORYLATION; SKIN; SPINAL GANGLION; TRANSGENIC MOUSE;

ANIMALS; CLUSTER ANALYSIS; GANGLIA, SPINAL; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; INTERLEUKINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NERVE FIBERS; PHOSPHORYLATION; PRURITUS; SENSORY RECEPTOR CELLS; SKIN; STAT3 TRANSCRIPTION FACTOR; TH2 CELLS;

EID: 84969579649     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2016.02.020     Document Type: Article

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