CNTF regulates neurite outgrowth and neuronal migration through JAK2/STAT3 and PI3K/Akt signaling pathways of DRG explants with gp120-induced neurotoxicity in vitro

Neuroscience Letters

Volumn 569, Issue , 2014, Pages 110-115

  Liu, Huaxiang ^a   Liu, Guixiang ^b   Bi, Yanwen ^a  

^a SHANDONG UNIVERSITY   (China)

^b BINZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Ciliary neurotrophic factor; Dorsal root ganglion; Gp120; HIV; Neuropathy; Neurotoxicity

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CILIARY NEUROTROPHIC FACTOR; GLYCOPROTEIN GP 120; JANUS KINASE 2; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; NEUROMODULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; MESSENGER RNA; STAT3 PROTEIN, RAT;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL MIGRATION; CELL PROTECTION; CONTROLLED STUDY; EMBRYO; EXPLANT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; NERVE FIBER GROWTH; NEUROTOXICITY; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SPINAL GANGLION; THERAPY EFFECT; ANIMAL; CELL MOTION; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS; METABOLISM; NERVE CELL; NEURITE; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PHYSIOLOGY; TOXICITY; VIROLOGY; WISTAR RAT;

ANIMALS; APOPTOSIS; CELL MOVEMENT; CILIARY NEUROTROPHIC FACTOR; GANGLIA, SPINAL; GAP-43 PROTEIN; HIV; HIV ENVELOPE PROTEIN GP120; JANUS KINASE 2; NEURITES; NEURONS; ORGAN CULTURE TECHNIQUES; PERIPHERAL NERVOUS SYSTEM DISEASES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84898994139     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2014.03.071     Document Type: Article

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