메뉴 건너뛰기




Volumn 171, Issue 22, 2014, Pages 5049-5058

Anti-IL-31 receptor antibody is shown to be a potential therapeutic option for treating itch and dermatitis in mice

Author keywords

[No Author keywords available]

Indexed keywords

BM 095; DEXAMETHASONE; INTERLEUKIN 31; INTERLEUKIN 31 RECEPTOR ALPHA NEUTRALIZING ANTIBODY; MONOCLONAL ANTIBODY; NALOXONE; NEUTRALIZING ANTIBODY; TACROLIMUS; TERFENADINE; UNCLASSIFIED DRUG; ANTIALLERGIC AGENT; IL31RA PROTEIN, MOUSE; INTERLEUKIN DERIVATIVE; INTERLEUKIN RECEPTOR; INTERLEUKIN-31, MOUSE; RECOMBINANT PROTEIN;

EID: 84915818539     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12823     Document Type: Article
Times cited : (68)

References (58)
  • 3
    • 84884719865 scopus 로고    scopus 로고
    • A single dose of interleukin-31 (IL-31) causes continuous itch-associated scratching behaviour in mice
    • Arai I, Tsuji M, Takeda H, Akiyama N, Saito S (2013). A single dose of interleukin-31 (IL-31) causes continuous itch-associated scratching behaviour in mice. Exp Dermatol 22: 669-671.
    • (2013) Exp Dermatol , vol.22 , pp. 669-671
    • Arai, I.1    Tsuji, M.2    Takeda, H.3    Akiyama, N.4    Saito, S.5
  • 4
    • 0034937094 scopus 로고    scopus 로고
    • Topical tacrolimus for the treatment of inflammatory skin diseases
    • Assmann T, Homey B, Ruzicka T (2001). Topical tacrolimus for the treatment of inflammatory skin diseases. Expert Opin Pharmacother 2: 1167-1175.
    • (2001) Expert Opin Pharmacother , vol.2 , pp. 1167-1175
    • Assmann, T.1    Homey, B.2    Ruzicka, T.3
  • 5
    • 33750375822 scopus 로고    scopus 로고
    • Complete overlap of interleukin-31 receptor A and oncostatin M receptor beta in the adult dorsal root ganglia with distinct developmental expression patterns
    • Bando T, Morikawa Y, Komori T, Senba E (2006). Complete overlap of interleukin-31 receptor A and oncostatin M receptor beta in the adult dorsal root ganglia with distinct developmental expression patterns. Neuroscience 142: 1263-1271.
    • (2006) Neuroscience , vol.142 , pp. 1263-1271
    • Bando, T.1    Morikawa, Y.2    Komori, T.3    Senba, E.4
  • 8
    • 31944434545 scopus 로고    scopus 로고
    • IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis
    • Bilsborough J, Leung DY, Maurer M, Howell M, Boguniewicz M, Yao L et al. (2006). IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis. J Allergy Clin Immunol 117: 418-425.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 418-425
    • Bilsborough, J.1    Leung, D.Y.2    Maurer, M.3    Howell, M.4    Boguniewicz, M.5    Yao, L.6
  • 9
    • 77953963592 scopus 로고    scopus 로고
    • Activation of human eosinophils and epidermal keratinocytes by Th2 cytokine IL-31: Implication for the immunopathogenesis of atopic dermatitis
    • Cheung PF, Wong CK, Ho AW, Hu S, Chen DP, Lam CW (2010). Activation of human eosinophils and epidermal keratinocytes by Th2 cytokine IL-31: implication for the immunopathogenesis of atopic dermatitis. Int Immunol 22: 453-467.
    • (2010) Int Immunol , vol.22 , pp. 453-467
    • Cheung, P.F.1    Wong, C.K.2    Ho, A.W.3    Hu, S.4    Chen, D.P.5    Lam, C.W.6
  • 12
    • 79751508913 scopus 로고    scopus 로고
    • Serum measurement of interleukin-31 (IL-31) in paediatric atopic dermatitis: Elevated levels correlate with severity scoring
    • Ezzat MH, Hasan ZE, Shaheen KY (2011). Serum measurement of interleukin-31 (IL-31) in paediatric atopic dermatitis: elevated levels correlate with severity scoring. J Eur Acad Dermatol Venereol 25: 334-339.
    • (2011) J Eur Acad Dermatol Venereol , vol.25 , pp. 334-339
    • Ezzat, M.H.1    Hasan, Z.E.2    Shaheen, K.Y.3
  • 13
    • 28444477328 scopus 로고    scopus 로고
    • Astilbin inhibits contact hypersensitivity through negative cytokine regulation distinct from cyclosporin A
    • Fei M, Wu X, Xu Q (2005). Astilbin inhibits contact hypersensitivity through negative cytokine regulation distinct from cyclosporin A. J Allergy Clin Immunol 116: 1350-1356.
    • (2005) J Allergy Clin Immunol , vol.116 , pp. 1350-1356
    • Fei, M.1    Wu, X.2    Xu, Q.3
  • 14
    • 0034921314 scopus 로고    scopus 로고
    • Quality of life in atopic dermatitis
    • Finlay AY (2001). Quality of life in atopic dermatitis. J Am Acad Dermatol 45 (1 Suppl.): S64-S66.
    • (2001) J Am Acad Dermatol , vol.45 , Issue.1 , pp. S64-S66
    • Finlay, A.Y.1
  • 15
    • 84872700908 scopus 로고    scopus 로고
    • Interleukin-31: Its role in canine pruritus and naturally occurring canine atopic dermatitis
    • e11-e42
    • Gonzales AJ, Humphrey WR, Messamore JE, Fleck TJ, Fici GJ, Shelly JA et al. (2013). Interleukin-31: its role in canine pruritus and naturally occurring canine atopic dermatitis. Vet Dermatol 24: 48-53, e11-e42.
    • (2013) Vet Dermatol , vol.24 , pp. 48-53
    • Gonzales, A.J.1    Humphrey, W.R.2    Messamore, J.E.3    Fleck, T.J.4    Fici, G.J.5    Shelly, J.A.6
  • 18
    • 0025743390 scopus 로고
    • Discharge patterns of human C-fibers induced by itching and burning stimuli
    • Handwerker HO, Forster C, Kirchhoff C (1991). Discharge patterns of human C-fibers induced by itching and burning stimuli. J Neurophysiol 66: 307-315.
    • (1991) J Neurophysiol , vol.66 , pp. 307-315
    • Handwerker, H.O.1    Forster, C.2    Kirchhoff, C.3
  • 19
    • 0032763423 scopus 로고    scopus 로고
    • Diagnostic criteria for atopic dermatitis: Consider the context
    • Hanifin JM (1999). Diagnostic criteria for atopic dermatitis: consider the context. Arch Dermatol 135: 1551.
    • (1999) Arch Dermatol , vol.135 , pp. 1551
    • Hanifin, J.M.1
  • 20
    • 0032833699 scopus 로고    scopus 로고
    • Update on therapy of atopic dermatitis
    • Hanifin JM, Tofte SJ (1999). Update on therapy of atopic dermatitis. J Allergy Clin Immunol 104 (3 Pt 2): S123-S125.
    • (1999) J Allergy Clin Immunol , vol.104 , Issue.3 , pp. S123-S125
    • Hanifin, J.M.1    Tofte, S.J.2
  • 21
    • 84892727105 scopus 로고    scopus 로고
    • Interleukin-31 does not induce immediate itch in atopic dermatitis patients and healthy controls after skin challenge
    • Hawro T, Saluja R, Weller K, Altrichter S, Metz M, Maurer M (2014). Interleukin-31 does not induce immediate itch in atopic dermatitis patients and healthy controls after skin challenge. Allergy 69: 113-117.
    • (2014) Allergy , vol.69 , pp. 113-117
    • Hawro, T.1    Saluja, R.2    Weller, K.3    Altrichter, S.4    Metz, M.5    Maurer, M.6
  • 22
    • 0037135028 scopus 로고    scopus 로고
    • Involvement of unique mechanisms in the induction of scratching behavior in BALB/c mice by compound 48/80
    • Inagaki N, Igeta K, Kim JF, Nagao M, Shiraishi N, Nakamura N et al. (2002). Involvement of unique mechanisms in the induction of scratching behavior in BALB/c mice by compound 48/80. Eur J Pharmacol 448: 175-183.
    • (2002) Eur J Pharmacol , vol.448 , pp. 175-183
    • Inagaki, N.1    Igeta, K.2    Kim, J.F.3    Nagao, M.4    Shiraishi, N.5    Nakamura, N.6
  • 24
    • 0036408775 scopus 로고    scopus 로고
    • Protective and curative effects of topically applied CX-659S, a novel diaminouracil derivative, on chronic picryl chloride-induced contact hypersensitivity responses
    • Inoue Y, Isobe M, Shiohara T, Goto Y, Hayashi H (2002). Protective and curative effects of topically applied CX-659S, a novel diaminouracil derivative, on chronic picryl chloride-induced contact hypersensitivity responses. Br J Dermatol 147: 675-682.
    • (2002) Br J Dermatol , vol.147 , pp. 675-682
    • Inoue, Y.1    Isobe, M.2    Shiohara, T.3    Goto, Y.4    Hayashi, H.5
  • 25
    • 77951885440 scopus 로고    scopus 로고
    • Interleukin (IL)-31 induces pro-inflammatory cytokines in human monocytes and macrophages following stimulation with staphylococcal exotoxins
    • Kasraie S, Niebuhr M, Werfel T (2010). Interleukin (IL)-31 induces pro-inflammatory cytokines in human monocytes and macrophages following stimulation with staphylococcal exotoxins. Allergy 65: 712-721.
    • (2010) Allergy , vol.65 , pp. 712-721
    • Kasraie, S.1    Niebuhr, M.2    Werfel, T.3
  • 26
    • 77952238977 scopus 로고    scopus 로고
    • Scratching behavior does not necessarily correlate with epidermal nerve fiber sprouting or inflammatory cell infiltration
    • Kido M, Takeuchi S, Esaki H, Hayashida S, Furue M (2010). Scratching behavior does not necessarily correlate with epidermal nerve fiber sprouting or inflammatory cell infiltration. J Dermatol Sci 58: 130-135.
    • (2010) J Dermatol Sci , vol.58 , pp. 130-135
    • Kido, M.1    Takeuchi, S.2    Esaki, H.3    Hayashida, S.4    Furue, M.5
  • 28
    • 63249117899 scopus 로고    scopus 로고
    • Effects of tacrolimus ointment on the expression of substance P, nerve growth factor, and neurotrophin-3 in atopic dermatitis
    • Kim HO, Lee CH, Ahn HK, Park CW (2009). Effects of tacrolimus ointment on the expression of substance P, nerve growth factor, and neurotrophin-3 in atopic dermatitis. Int J Dermatol 48: 431-438.
    • (2009) Int J Dermatol , vol.48 , pp. 431-438
    • Kim, H.O.1    Lee, C.H.2    Ahn, H.K.3    Park, C.W.4
  • 29
    • 0029561435 scopus 로고
    • Immediate-type hypersensitivity response followed by a late reaction is induced by repeated epicutaneous application of contact sensitizing agents in mice
    • Kitagaki H, Fujisawa S, Watanabe K, Hayakawa K, Shiohara T (1995). Immediate-type hypersensitivity response followed by a late reaction is induced by repeated epicutaneous application of contact sensitizing agents in mice. J Invest Dermatol 105: 749-755.
    • (1995) J Invest Dermatol , vol.105 , pp. 749-755
    • Kitagaki, H.1    Fujisawa, S.2    Watanabe, K.3    Hayakawa, K.4    Shiohara, T.5
  • 30
    • 0031225486 scopus 로고    scopus 로고
    • Repeated elicitation of contact hypersensitivity induces a shift in cutaneous cytokine milieu from a T helper cell type 1 to a T helper cell type 2 profile
    • Kitagaki H, Ono N, Hayakawa K, Kitazawa T, Watanabe K, Shiohara T (1997). Repeated elicitation of contact hypersensitivity induces a shift in cutaneous cytokine milieu from a T helper cell type 1 to a T helper cell type 2 profile. J Immunol 159: 2484-2491.
    • (1997) J Immunol , vol.159 , pp. 2484-2491
    • Kitagaki, H.1    Ono, N.2    Hayakawa, K.3    Kitazawa, T.4    Watanabe, K.5    Shiohara, T.6
  • 31
    • 0032801364 scopus 로고    scopus 로고
    • An evidence-based review of the efficacy of antihistamines in relieving pruritus in atopic dermatitis
    • Klein PA, Clark RA (1999). An evidence-based review of the efficacy of antihistamines in relieving pruritus in atopic dermatitis. Arch Dermatol 135: 1522-1525.
    • (1999) Arch Dermatol , vol.135 , pp. 1522-1525
    • Klein, P.A.1    Clark, R.A.2
  • 32
    • 0032830188 scopus 로고    scopus 로고
    • Itching and the atopic skin
    • Koblenzer CS (1999). Itching and the atopic skin. J Allergy Clin Immunol 104 (3 Pt 2): S109-S113.
    • (1999) J Allergy Clin Immunol , vol.104 , Issue.3 , pp. S109-S113
    • Koblenzer, C.S.1
  • 33
    • 0037143717 scopus 로고    scopus 로고
    • IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions
    • Konishi H, Tsutsui H, Murakami T, Yumikura-Futatsugi S, Yamanaka K, Tanaka M et al. (2002). IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions. Proc Natl Acad Sci U S A 99: 11340-11345.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 11340-11345
    • Konishi, H.1    Tsutsui, H.2    Murakami, T.3    Yumikura-Futatsugi, S.4    Yamanaka, K.5    Tanaka, M.6
  • 34
    • 77954331629 scopus 로고    scopus 로고
    • Guidelines for reporting experiments involving animals: The ARRIVE guidelines
    • McGrath J, Drummond G, McLachlan E, Kilkenny C, Wainwright C (2010). Guidelines for reporting experiments involving animals: the ARRIVE guidelines. Br J Pharmacol 160: 1573-1576.
    • (2010) Br J Pharmacol , vol.160 , pp. 1573-1576
    • McGrath, J.1    Drummond, G.2    McLachlan, E.3    Kilkenny, C.4    Wainwright, C.5
  • 35
    • 79952363470 scopus 로고    scopus 로고
    • Pruritus: An overview of current concepts
    • Metz M, Grundmann S, Stander S (2011). Pruritus: an overview of current concepts. Vet Dermatol 22: 121-131.
    • (2011) Vet Dermatol , vol.22 , pp. 121-131
    • Metz, M.1    Grundmann, S.2    Stander, S.3
  • 36
    • 0024309482 scopus 로고
    • Efficacy and safety of nalmefene in patients with severe pruritus caused by chronic urticaria and atopic dermatitis
    • Monroe EW (1989). Efficacy and safety of nalmefene in patients with severe pruritus caused by chronic urticaria and atopic dermatitis. J Am Acad Dermatol 21: 135-136.
    • (1989) J Am Acad Dermatol , vol.21 , pp. 135-136
    • Monroe, E.W.1
  • 37
    • 33749334907 scopus 로고    scopus 로고
    • Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis
    • Neis MM, Peters B, Dreuw A, Wenzel J, Bieber T, Mauch C et al. (2006). Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis. J Allergy Clin Immunol 118: 930-937.
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 930-937
    • Neis, M.M.1    Peters, B.2    Dreuw, A.3    Wenzel, J.4    Bieber, T.5    Mauch, C.6
  • 38
    • 77951626078 scopus 로고    scopus 로고
    • Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells
    • Niyonsaba F, Ushio H, Hara M, Yokoi H, Tominaga M, Takamori K et al. (2010). Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells. J Immunol 184: 3526-3534.
    • (2010) J Immunol , vol.184 , pp. 3526-3534
    • Niyonsaba, F.1    Ushio, H.2    Hara, M.3    Yokoi, H.4    Tominaga, M.5    Takamori, K.6
  • 39
    • 0345800718 scopus 로고    scopus 로고
    • Immune mechanisms leading to atopic dermatitis
    • Novak N, Bieber T, Leung DY (2003). Immune mechanisms leading to atopic dermatitis. J Allergy Clin Immunol 112 (6 Suppl.): S128-S139.
    • (2003) J Allergy Clin Immunol , vol.112 , Issue.6 , pp. S128-S139
    • Novak, N.1    Bieber, T.2    Leung, D.Y.3
  • 40
    • 0028180224 scopus 로고
    • In vitro effects of H1-antihistamines on histamine and PGD2 release from mast cells of human lung, tonsil, and skin
    • Okayama Y, Benyon RC, Lowman MA, Church MK (1994). In vitro effects of H1-antihistamines on histamine and PGD2 release from mast cells of human lung, tonsil, and skin. Allergy 49: 246-253.
    • (1994) Allergy , vol.49 , pp. 246-253
    • Okayama, Y.1    Benyon, R.C.2    Lowman, M.A.3    Church, M.K.4
  • 41
    • 33646418808 scopus 로고    scopus 로고
    • Frontiers in pruritus research: Scratching the brain for more effective itch therapy
    • Paus R, Schmelz M, Biro T, Steinhoff M (2006). Frontiers in pruritus research: scratching the brain for more effective itch therapy. J Clin Invest 116: 1174-1186.
    • (2006) J Clin Invest , vol.116 , pp. 1174-1186
    • Paus, R.1    Schmelz, M.2    Biro, T.3    Steinhoff, M.4
  • 42
    • 84891791940 scopus 로고    scopus 로고
    • The IUPHAR/BPS Guide to PHARMACOLOGY: An expert-driven knowledgebase of drug targets and their ligands
    • Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SP, Buneman OP et al. (2014). The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. Nucl Acids Res 42 (Database Issue): D1098-106.
    • (2014) Nucl Acids Res , vol.42 , pp. D1098-D1106
    • Pawson, A.J.1    Sharman, J.L.2    Benson, H.E.3    Faccenda, E.4    Alexander, S.P.5    Buneman, O.P.6
  • 44
    • 0033954276 scopus 로고    scopus 로고
    • FK506 inhibition of histamine release and cytokine production by mast cells and basophils
    • Sengoku T, Kishi S, Sakuma S, Ohkubo Y, Goto T (2000). FK506 inhibition of histamine release and cytokine production by mast cells and basophils. Int J Immunopharmacol 22: 189-201.
    • (2000) Int J Immunopharmacol , vol.22 , pp. 189-201
    • Sengoku, T.1    Kishi, S.2    Sakuma, S.3    Ohkubo, Y.4    Goto, T.5
  • 46
    • 0036485026 scopus 로고    scopus 로고
    • Pathophysiology of pruritus in atopic dermatitis: An overview
    • Stander S, Steinhoff M (2002). Pathophysiology of pruritus in atopic dermatitis: an overview. Exp Dermatol 11: 12-24.
    • (2002) Exp Dermatol , vol.11 , pp. 12-24
    • Stander, S.1    Steinhoff, M.2
  • 48
    • 0038771253 scopus 로고    scopus 로고
    • Analysis of the spontaneous scratching behavior by NC/Nga mice: A possible approach to evaluate antipruritics for subjects with atopic dermatitis
    • Takano N, Arai I, Kurachi M (2003). Analysis of the spontaneous scratching behavior by NC/Nga mice: a possible approach to evaluate antipruritics for subjects with atopic dermatitis. Eur J Pharmacol 471: 223-228.
    • (2003) Eur J Pharmacol , vol.471 , pp. 223-228
    • Takano, N.1    Arai, I.2    Kurachi, M.3
  • 49
    • 3142585530 scopus 로고    scopus 로고
    • Evaluation of antipruritic effects of several agents on scratching behavior by NC/Nga mice
    • Takano N, Arai I, Hashimoto Y, Kurachi M (2004). Evaluation of antipruritic effects of several agents on scratching behavior by NC/Nga mice. Eur J Pharmacol 495: 159-165.
    • (2004) Eur J Pharmacol , vol.495 , pp. 159-165
    • Takano, N.1    Arai, I.2    Hashimoto, Y.3    Kurachi, M.4
  • 51
    • 33645934213 scopus 로고    scopus 로고
    • Involvement of IL-31 on scratching behavior in NC/Nga mice with atopic-like dermatitis
    • Takaoka A, Arai I, Sugimoto M, Honma Y, Futaki N, Nakamura A et al. (2006). Involvement of IL-31 on scratching behavior in NC/Nga mice with atopic-like dermatitis. Exp Dermatol 15: 161-167.
    • (2006) Exp Dermatol , vol.15 , pp. 161-167
    • Takaoka, A.1    Arai, I.2    Sugimoto, M.3    Honma, Y.4    Futaki, N.5    Nakamura, A.6
  • 52
    • 0026288938 scopus 로고
    • Itch and atopic dermatitis: Clinical and experimental studies
    • Wahlgren CF (1991). Itch and atopic dermatitis: clinical and experimental studies. Acta Derm Venereol Suppl (Stockh) 165: 1-53.
    • (1991) Acta Derm Venereol Suppl (Stockh) , vol.165 , pp. 1-53
    • Wahlgren, C.F.1
  • 53
    • 0027983717 scopus 로고
    • The U.K. Working party's diagnostic criteria for atopic dermatitis. III. Independent hospital validation
    • Williams HC, Burney PG, Pembroke AC, Hay RJ (1994). The U.K. working party's diagnostic criteria for atopic dermatitis. III. Independent hospital validation. Br J Dermatol 131: 406-416.
    • (1994) Br J Dermatol , vol.131 , pp. 406-416
    • Williams, H.C.1    Burney, P.G.2    Pembroke, A.C.3    Hay, R.J.4
  • 54
    • 0029913787 scopus 로고    scopus 로고
    • T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: Interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (Il) 4/Il-10-producing (Th2) negative regulatory CD4+ T cells
    • Xu H, DiIulio NA, Fairchild RL (1996). T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (Il) 4/Il-10-producing (Th2) negative regulatory CD4+ T cells. J Exp Med 183: 1001-1012.
    • (1996) J Exp Med , vol.183 , pp. 1001-1012
    • Xu, H.1    Diiulio, N.A.2    Fairchild, R.L.3
  • 55
    • 67650261620 scopus 로고    scopus 로고
    • Proteomic approach to FcepsilonRI aggregation-initiated signal transduction cascade in human mast cells
    • Yamaoka K, Okayama Y, Kaminuma O, Katayama K, Mori A, Tatsumi H et al. (2009). Proteomic Approach to FcepsilonRI aggregation-initiated signal transduction cascade in human mast cells. Int Arch Allergy Immunol 149 (Suppl. 1): 73-76.
    • (2009) Int Arch Allergy Immunol , vol.149 , pp. 73-76
    • Yamaoka, K.1    Okayama, Y.2    Kaminuma, O.3    Katayama, K.4    Mori, A.5    Tatsumi, H.6
  • 56
    • 19644372573 scopus 로고    scopus 로고
    • Dermal mast cells play a central role in the incidence of scratching behavior in mice induced by multiple application of the hapten, 2,4,6-trinitrochlorobenzene
    • Yamashita H, Michibata Y, Mizukami H, Ogihara Y, Morita A, Nose M (2005). Dermal mast cells play a central role in the incidence of scratching behavior in mice induced by multiple application of the hapten, 2,4,6-trinitrochlorobenzene. Exp Dermatol 14: 438-444.
    • (2005) Exp Dermatol , vol.14 , pp. 438-444
    • Yamashita, H.1    Michibata, Y.2    Mizukami, H.3    Ogihara, Y.4    Morita, A.5    Nose, M.6
  • 57
    • 34247126112 scopus 로고    scopus 로고
    • Pharmacological characterization of a chronic pruritus model induced by multiple application of 2,4,6-trinitrochlorobenzene in NC mice
    • Yamashita H, Makino T, Mizukami H, Nose M (2007). Pharmacological characterization of a chronic pruritus model induced by multiple application of 2,4,6-trinitrochlorobenzene in NC mice. Eur J Pharmacol 563: 233-239.
    • (2007) Eur J Pharmacol , vol.563 , pp. 233-239
    • Yamashita, H.1    Makino, T.2    Mizukami, H.3    Nose, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.