Curcumin bioavailability from oil in water nano-emulsions: In vitro and in vivo study on the dimensional, compositional and interactional dependence

Journal of Controlled Release

Volumn 233, Issue , 2016, Pages 88-100

  Vecchione, Raffaele ^a,b   Quagliariello, Vincenzo ^c   Calabria, Dominic ^b   Calcagno, Vincenzo ^a,b   De Luca, Elisa ^a   Iaffaioli, Rosario V ^c   Netti, Paolo A ^a,b  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

2 Iminothiolane; Chitosan; Colon cancer; Curcumin; Nano emulsions; Piperine

Indexed keywords

BIOCHEMISTRY; CELL CULTURE; CHITIN; CHITOSAN; CYTOTOXICITY; DISEASES; EMULSIFICATION; OILS AND FATS; PHARMACOKINETICS;

2-IMINOTHIOLANE; COLON CANCER; CURCUMIN; NANO-EMULSIONS; PIPERINE;

EMULSIONS;

CHITOSAN; CURCUMIN; LIPOPOLYSACCHARIDE; NANOCARRIER; PIPERINE; THIOL; 1,3 BENZODIOXOLE DERIVATIVE; ALKALOID; AMIDE; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; IMIDOESTER; METHYL 4-MERCAPTOBUTYRIMIDATE; NANOPARTICLE; PIPERIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; FIBROBLAST CULTURE; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; NANOEMULSION; NONHUMAN; OIL IN WATER NANOEMULSION; PRIORITY JOURNAL; RAT; SYNTHESIS; ANIMAL; BIOAVAILABILITY; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; DRUG INTERACTION; DRUG STABILITY; EMULSION; FIBROBLAST; HT-29 CELL LINE; HUMAN; MOUSE; NIH 3T3 CELL LINE; PARTICLE SIZE; SURFACE PROPERTY; TISSUE DISTRIBUTION; WISTAR RAT;

ALKALOIDS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; BENZODIOXOLES; BIOLOGICAL AVAILABILITY; CELL SURVIVAL; CHITOSAN; CURCUMIN; DRUG INTERACTIONS; DRUG STABILITY; EMULSIONS; FIBROBLASTS; HT29 CELLS; HUMANS; IMIDOESTERS; MALE; MICE; NANOPARTICLES; NIH 3T3 CELLS; PARTICLE SIZE; PIPERIDINES; POLYUNSATURATED ALKAMIDES; RATS, WISTAR; SURFACE PROPERTIES; TISSUE DISTRIBUTION;

EID: 84969492178     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2016.05.004     Document Type: Article

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