DNA methylation profiling reveals differences in the 3 human monocyte subsets and identifies uremia to induce DNA methylation changes during differentiation

Epigenetics

Volumn 11, Issue 4, 2016, Pages 259-272

  Zawada, Adam M ^a   Schneider, Jenny S ^a   Michel, Anne I ^a   Rogacev, Kyrill S ^a,b   Hummel, Björn ^a   Krezdorn, Nicolas ^c   Müller, Soeren ^c,d   Rotter, Björn ^c   Winter, Peter ^c   Obeid, Rima ^a   Geisel, Jürgen ^a   Fliser, Danilo ^a   Heine, Gunnar H ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c GENXPRO GMBH   (Germany)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CD14; CD16; chronic kidney disease; DNA methylation; monocyte subsets; S adenosylhomocysteine

Indexed keywords

ADULT; AGED; ARTICLE; CELL DIFFERENTIATION; CHRONIC KIDNEY DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DIALYSIS; DNA METHYLATION; EPIGENETICS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; MALE; MIDDLE AGED; MONOCYTE; NEXT GENERATION SEQUENCING; PHAGOCYTOSIS; SEQUENCE ANALYSIS; UREMIA; CHRONIC KIDNEY FAILURE; GENE EXPRESSION REGULATION; GENETICS; HIGH THROUGHPUT SEQUENCING; METABOLISM; NORMAL HUMAN; PATHOLOGY;

BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; CD135 ANTIGEN; CD14 ANTIGEN; FC RECEPTOR; FCGR3B PROTEIN, HUMAN; FLT3 PROTEIN, HUMAN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; HDAC1 PROTEIN, HUMAN; HISTONE DEACETYLASE 1; MNT PROTEIN, HUMAN; REPRESSOR PROTEIN; S ADENOSYLHOMOCYSTEINE;

ANTIGENS, CD14; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; DNA METHYLATION; FMS-LIKE TYROSINE KINASE 3; GENE EXPRESSION REGULATION; GPI-LINKED PROTEINS; HEALTHY VOLUNTEERS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HISTONE DEACETYLASE 1; HUMANS; MONOCYTES; RECEPTORS, IGG; RENAL INSUFFICIENCY, CHRONIC; REPRESSOR PROTEINS; S-ADENOSYLHOMOCYSTEINE; UREMIA;

EID: 84969248257     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.1080/15592294.2016.1158363     Document Type: Article

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