메뉴 건너뛰기




Volumn 176, Issue , 2016, Pages 50-57

Leptospira spp.: Novel insights into host–pathogen interactions

Author keywords

Extracellular matrix; Leptospira; Plasma components

Indexed keywords

ADHESIN; ANTIGEN; BACTERIAL PROTEIN; BINDING PROTEIN; COMPLEMENT; FIBRINOGEN; FIBRINOGEN RECEPTOR; LEPTOSPIROSIS VACCINE; PLASMINOGEN; RECOMBINANT PROTEIN; SCLEROPROTEIN;

EID: 84968571678     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2015.12.004     Document Type: Article
Times cited : (37)

References (90)
  • 2
    • 79960126040 scopus 로고    scopus 로고
    • Adhesion mechanisms of Borrelia burgdorferi
    • Antonara, S., Ristow, L., Coburn, J., Adhesion mechanisms of Borrelia burgdorferi. Adv. Exp. Med. Biol. 715 (2011), 35–49.
    • (2011) Adv. Exp. Med. Biol. , vol.715 , pp. 35-49
    • Antonara, S.1    Ristow, L.2    Coburn, J.3
  • 6
    • 77953940510 scopus 로고    scopus 로고
    • Functional characterization of LcpA, a surface-exposed protein of Leptospira spp. that binds the human complement regulator C4BP
    • Barbosa, A.S., Monaris, D., Silva, L.B., Morais, Z.M., Vasconcellos, S.A., Cianciarullo, A.M., Isaac, L., Abreu, P.A., Functional characterization of LcpA, a surface-exposed protein of Leptospira spp. that binds the human complement regulator C4BP. Infect. Immun. 78 (2010), 3207–3216.
    • (2010) Infect. Immun. , vol.78 , pp. 3207-3216
    • Barbosa, A.S.1    Monaris, D.2    Silva, L.B.3    Morais, Z.M.4    Vasconcellos, S.A.5    Cianciarullo, A.M.6    Isaac, L.7    Abreu, P.A.8
  • 9
    • 0036865204 scopus 로고    scopus 로고
    • Structural and functional studies of complement inhibitor C4b-binding protein
    • Blom, A.M., Structural and functional studies of complement inhibitor C4b-binding protein. Biochem. Soc. Trans. 30 (2002), 978–982.
    • (2002) Biochem. Soc. Trans. , vol.30 , pp. 978-982
    • Blom, A.M.1
  • 10
    • 68249086824 scopus 로고    scopus 로고
    • Complement evasion strategies of pathogens-acquisition of inhibitors and beyond
    • Blom, A.M., Hallstrom, T., Riesbeck, K., Complement evasion strategies of pathogens-acquisition of inhibitors and beyond. Mol. Immunol. 46 (2009), 2808–2817.
    • (2009) Mol. Immunol. , vol.46 , pp. 2808-2817
    • Blom, A.M.1    Hallstrom, T.2    Riesbeck, K.3
  • 11
    • 84860702400 scopus 로고    scopus 로고
    • Impenetrable barriers or entry portals? The role of cell-cell adhesion during infection
    • Bonazzi, M., Cossart, P., Impenetrable barriers or entry portals? The role of cell-cell adhesion during infection. J. Cell Biol. 195 (2011), 349–358.
    • (2011) J. Cell Biol. , vol.195 , pp. 349-358
    • Bonazzi, M.1    Cossart, P.2
  • 12
    • 0034778155 scopus 로고    scopus 로고
    • Identification of the hemolysis-associated protein 1 as a cross-protective immunogen of Leptospira interrogans by adenovirus-mediated vaccination
    • Branger, C., Sonrier, C., Chatrenet, B., Klonjkowski, B., Ruvoen-Clouet, N., Aubert, A., Andre-Fontaine, G., Eloit, M., Identification of the hemolysis-associated protein 1 as a cross-protective immunogen of Leptospira interrogans by adenovirus-mediated vaccination. Infect. immun. 69 (2001), 6831–6838.
    • (2001) Infect. immun. , vol.69 , pp. 6831-6838
    • Branger, C.1    Sonrier, C.2    Chatrenet, B.3    Klonjkowski, B.4    Ruvoen-Clouet, N.5    Aubert, A.6    Andre-Fontaine, G.7    Eloit, M.8
  • 17
    • 84868192681 scopus 로고    scopus 로고
    • Sequence of Leptospira santarosai serovar Shermani genome and prediction of virulence-associated genes
    • Chou, L.F., Chen, Y.T., Lu, C.W., Ko, Y.C., Tang, C.Y., Pan, M.J., Tian, Y.C., Chiu, C.H., Hung, C.C., Yang, C.W., Sequence of Leptospira santarosai serovar Shermani genome and prediction of virulence-associated genes. Gene 511 (2012), 364–370.
    • (2012) Gene , vol.511 , pp. 364-370
    • Chou, L.F.1    Chen, Y.T.2    Lu, C.W.3    Ko, Y.C.4    Tang, C.Y.5    Pan, M.J.6    Tian, Y.C.7    Chiu, C.H.8    Hung, C.C.9    Yang, C.W.10
  • 18
    • 34248368916 scopus 로고    scopus 로고
    • Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen
    • Choy, H.A., Kelley, M.M., Chen, T.L., Moller, A.K., Matsunaga, J., Haake, D.A., Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen. Infect. Immun. 75 (2007), 2441–2450.
    • (2007) Infect. Immun. , vol.75 , pp. 2441-2450
    • Choy, H.A.1    Kelley, M.M.2    Chen, T.L.3    Moller, A.K.4    Matsunaga, J.5    Haake, D.A.6
  • 19
    • 79951803975 scopus 로고    scopus 로고
    • The multifunctional LigB adhesin binds homeostatic proteins with potential roles in cutaneous infection by pathogenic Leptospira interrogans
    • Choy, H.A., Kelley, M.M., Croda, J., Matsunaga, J., Babbitt, J.T., Ko, A.I., Picardeau, M., Haake, D.A., The multifunctional LigB adhesin binds homeostatic proteins with potential roles in cutaneous infection by pathogenic Leptospira interrogans. PloS One, 6, 2011, e16879.
    • (2011) PloS One , vol.6 , pp. e16879
    • Choy, H.A.1    Kelley, M.M.2    Croda, J.3    Matsunaga, J.4    Babbitt, J.T.5    Ko, A.I.6    Picardeau, M.7    Haake, D.A.8
  • 20
    • 78650251929 scopus 로고    scopus 로고
    • New insights into the pathogenicity of leptospires: evasion of host defences
    • Cinco, M., New insights into the pathogenicity of leptospires: evasion of host defences. The new microbiologica. 33 (2010), 283–292.
    • (2010) The new microbiologica. , vol.33 , pp. 283-292
    • Cinco, M.1
  • 21
    • 0035958880 scopus 로고    scopus 로고
    • SdrG, a fibrinogen-binding bacterial adhesin of the microbial surface components recognizing adhesive matrix molecules subfamily from Staphylococcus epidermidis, targets the thrombin cleavage site in the Bbeta chain
    • Davis, S.L., Gurusiddappa, S., McCrea, K.W., Perkins, S., Hook, M., SdrG, a fibrinogen-binding bacterial adhesin of the microbial surface components recognizing adhesive matrix molecules subfamily from Staphylococcus epidermidis, targets the thrombin cleavage site in the Bbeta chain. J. Biol. Chem. 276 (2001), 27799–27805.
    • (2001) J. Biol. Chem. , vol.276 , pp. 27799-27805
    • Davis, S.L.1    Gurusiddappa, S.2    McCrea, K.W.3    Perkins, S.4    Hook, M.5
  • 23
    • 17444449727 scopus 로고    scopus 로고
    • Comparative analysis of the LPS biosynthetic loci of the genetic subtypes of serovar Hardjo: Leptospira interrogans subtype Hardjoprajitno and Leptospira borgpetersenii subtype Hardjobovis
    • de la Pena-Moctezuma, A., Bulach, D.M., Kalambaheti, T., Adler, B., Comparative analysis of the LPS biosynthetic loci of the genetic subtypes of serovar Hardjo: Leptospira interrogans subtype Hardjoprajitno and Leptospira borgpetersenii subtype Hardjobovis. FEMS Microbiol. Lett. 177 (1999), 319–326.
    • (1999) FEMS Microbiol. Lett. , vol.177 , pp. 319-326
    • de la Pena-Moctezuma, A.1    Bulach, D.M.2    Kalambaheti, T.3    Adler, B.4
  • 26
    • 60149089675 scopus 로고    scopus 로고
    • Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein
    • Dong, H., Hu, Y., Xue, F., Sun, D., Ojcius, D.M., Mao, Y., Yan, J., Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein. BMC Microbiol., 8, 2008, 223.
    • (2008) BMC Microbiol. , vol.8 , pp. 223
    • Dong, H.1    Hu, Y.2    Xue, F.3    Sun, D.4    Ojcius, D.M.5    Mao, Y.6    Yan, J.7
  • 27
    • 18644365126 scopus 로고    scopus 로고
    • Leptospira and Leptospirosis. Melbourne, Australia
    • Faine, S., Adler, B., Bolin, C., Perolat, P., Leptospira and Leptospirosis. Melbourne, Australia. MediSci, 1999.
    • (1999) MediSci
    • Faine, S.1    Adler, B.2    Bolin, C.3    Perolat, P.4
  • 33
    • 0032702291 scopus 로고    scopus 로고
    • Leptospiral outer membrane proteins OmpL1 and LipL41 exhibit synergistic immunoprotection
    • Haake, D.A., Mazel, M.K., McCoy, A.M., Milward, F., Chao, G., Matsunaga, J., Wagar, E.A., Leptospiral outer membrane proteins OmpL1 and LipL41 exhibit synergistic immunoprotection. Infect. Immun. 67 (1999), 6572–6582.
    • (1999) Infect. Immun. , vol.67 , pp. 6572-6582
    • Haake, D.A.1    Mazel, M.K.2    McCoy, A.M.3    Milward, F.4    Chao, G.5    Matsunaga, J.6    Wagar, E.A.7
  • 34
    • 46249119468 scopus 로고    scopus 로고
    • In LipL32, the major leptospiral lipoprotein, the C terminus is the primary immunogenic domain and mediates interaction with collagen IV and plasma fibronectin
    • Hauk, P., Macedo, F., Romero, E.C., Vasconcellos, S.A., de Morais, Z.M., Barbosa, A.S., Ho, P.L., In LipL32, the major leptospiral lipoprotein, the C terminus is the primary immunogenic domain and mediates interaction with collagen IV and plasma fibronectin. Infect. Immun. 76 (2008), 2642–2650.
    • (2008) Infect. Immun. , vol.76 , pp. 2642-2650
    • Hauk, P.1    Macedo, F.2    Romero, E.C.3    Vasconcellos, S.A.4    de Morais, Z.M.5    Barbosa, A.S.6    Ho, P.L.7
  • 35
    • 42949159838 scopus 로고    scopus 로고
    • LipL32 is an extracellular matrix-interacting protein of Leptospira spp. and Pseudoalteromonas tunicata
    • Hoke, D.E., Egan, S., Cullen, P.A., Adler, B., LipL32 is an extracellular matrix-interacting protein of Leptospira spp. and Pseudoalteromonas tunicata. Infect. Immun. 76 (2008), 2063–2069.
    • (2008) Infect. Immun. , vol.76 , pp. 2063-2069
    • Hoke, D.E.1    Egan, S.2    Cullen, P.A.3    Adler, B.4
  • 36
    • 70349993608 scopus 로고    scopus 로고
    • Nationwide survey of leptospira antibodies in dogs in Japan: results from microscopic agglutination test and enzyme-linked immunosorbent assay
    • Iwamoto, E., Wada, Y., Fujisaki, Y., Umeki, S., Jones, M.Y., Mizuno, T., Itamoto, K., Maeda, K., Iwata, H., Okuda, M., Nationwide survey of leptospira antibodies in dogs in Japan: results from microscopic agglutination test and enzyme-linked immunosorbent assay. J. Vet. Med. Sci. 71 (2009), 1191–1199.
    • (2009) J. Vet. Med. Sci. , vol.71 , pp. 1191-1199
    • Iwamoto, E.1    Wada, Y.2    Fujisaki, Y.3    Umeki, S.4    Jones, M.Y.5    Mizuno, T.6    Itamoto, K.7    Maeda, K.8    Iwata, H.9    Okuda, M.10
  • 37
    • 1842456788 scopus 로고    scopus 로고
    • Leptospiral immunoglobulin-like proteins elicit protective immunity
    • Koizumi, N., Watanabe, H., Leptospiral immunoglobulin-like proteins elicit protective immunity. Vaccine 22 (2004), 1545–1552.
    • (2004) Vaccine , vol.22 , pp. 1545-1552
    • Koizumi, N.1    Watanabe, H.2
  • 38
    • 4644355088 scopus 로고    scopus 로고
    • The intracellular status of Streptococcus pyogenes: role of extracellular matrix-binding proteins and their regulation
    • Kreikemeyer, B., Klenk, M., Podbielski, A., The intracellular status of Streptococcus pyogenes: role of extracellular matrix-binding proteins and their regulation. Int. J. Med. Microbiol. 294 (2004), 177–188.
    • (2004) Int. J. Med. Microbiol. , vol.294 , pp. 177-188
    • Kreikemeyer, B.1    Klenk, M.2    Podbielski, A.3
  • 41
    • 79551669087 scopus 로고    scopus 로고
    • Leptospira immunoglobulin-like protein B (LigB) binding to the C-terminal fibrinogen alphaC domain inhibits fibrin clot formation, platelet adhesion and aggregation
    • Lin, Y.P., McDonough, S.P., Sharma, Y., Chang, Y.F., Leptospira immunoglobulin-like protein B (LigB) binding to the C-terminal fibrinogen alphaC domain inhibits fibrin clot formation, platelet adhesion and aggregation. Mol. Microbiol. 79 (2011), 1063–1076.
    • (2011) Mol. Microbiol. , vol.79 , pp. 1063-1076
    • Lin, Y.P.1    McDonough, S.P.2    Sharma, Y.3    Chang, Y.F.4
  • 42
    • 67749102258 scopus 로고    scopus 로고
    • Repeated domains of leptospira immunoglobulin-like proteins interact with elastin and tropoelastin
    • Lin, Y.P., Lee, D.W., McDonough, S.P., Nicholson, L.K., Sharma, Y., Chang, Y.F., Repeated domains of leptospira immunoglobulin-like proteins interact with elastin and tropoelastin. J. Biol. Chem. 284 (2009), 19380–19391.
    • (2009) J. Biol. Chem. , vol.284 , pp. 19380-19391
    • Lin, Y.P.1    Lee, D.W.2    McDonough, S.P.3    Nicholson, L.K.4    Sharma, Y.5    Chang, Y.F.6
  • 43
    • 23744470620 scopus 로고    scopus 로고
    • ClfA(221-550), a fibrinogen-binding segment of Staphylococcus aureus clumping factor A, disrupts fibrinogen function
    • Liu, C.Z., Shih, M.H., Tsai, P.J., ClfA(221-550), a fibrinogen-binding segment of Staphylococcus aureus clumping factor A, disrupts fibrinogen function. Thromb. Haemost. 94 (2005), 286–294.
    • (2005) Thromb. Haemost. , vol.94 , pp. 286-294
    • Liu, C.Z.1    Shih, M.H.2    Tsai, P.J.3
  • 45
    • 68449102172 scopus 로고    scopus 로고
    • Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans
    • Malmstrom, J., Beck, M., Schmidt, A., Lange, V., Deutsch, E.W., Aebersold, R., Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans. Nature 460 (2009), 762–765.
    • (2009) Nature , vol.460 , pp. 762-765
    • Malmstrom, J.1    Beck, M.2    Schmidt, A.3    Lange, V.4    Deutsch, E.W.5    Aebersold, R.6
  • 47
    • 11144298941 scopus 로고    scopus 로고
    • Osmolarity, a key environmental signal controlling expression of leptospiral proteins LigA and LigB and the extracellular release of LigA
    • Matsunaga, J., Sanchez, Y., Xu, X., Haake, D.A., Osmolarity, a key environmental signal controlling expression of leptospiral proteins LigA and LigB and the extracellular release of LigA. Infect. Immun. 73 (2005), 70–78.
    • (2005) Infect. Immun. , vol.73 , pp. 70-78
    • Matsunaga, J.1    Sanchez, Y.2    Xu, X.3    Haake, D.A.4
  • 50
    • 26244466048 scopus 로고    scopus 로고
    • Regulation of complement activation at the C3-level by serum resistant leptospires
    • Meri, T., Murgia, R., Stefanel, P., Meri, S., Cinco, M., Regulation of complement activation at the C3-level by serum resistant leptospires. Microb. Pathog. 39 (2005), 139–147.
    • (2005) Microb. Pathog. , vol.39 , pp. 139-147
    • Meri, T.1    Murgia, R.2    Stefanel, P.3    Meri, S.4    Cinco, M.5
  • 51
    • 0034175911 scopus 로고    scopus 로고
    • Identification of a 36-kDa fibronectin-binding protein expressed by a virulent variant of Leptospira interrogans serovar icterohaemorrhagiae
    • Merien, F., Truccolo, J., Baranton, G., Perolat, P., Identification of a 36-kDa fibronectin-binding protein expressed by a virulent variant of Leptospira interrogans serovar icterohaemorrhagiae. FEMS Microbiol. Lett. 185 (2000), 17–22.
    • (2000) FEMS Microbiol. Lett. , vol.185 , pp. 17-22
    • Merien, F.1    Truccolo, J.2    Baranton, G.3    Perolat, P.4
  • 54
    • 57149095722 scopus 로고    scopus 로고
    • Serodiagnosis of severe leptospirosis: evaluation of ELISA based on the recombinant OmpL1 or LipL41 antigens of Leptospira interrogans serovar autumnalis
    • Natarajaseenivasan, K., Vijayachari, P., Sharma, S., Sugunan, A.P., Selvin, J., Sehgal, S.C., Serodiagnosis of severe leptospirosis: evaluation of ELISA based on the recombinant OmpL1 or LipL41 antigens of Leptospira interrogans serovar autumnalis. Ann. Trop. Med. Parasitol. 102 (2008), 699–708.
    • (2008) Ann. Trop. Med. Parasitol. , vol.102 , pp. 699-708
    • Natarajaseenivasan, K.1    Vijayachari, P.2    Sharma, S.3    Sugunan, A.P.4    Selvin, J.5    Sehgal, S.C.6
  • 55
    • 1642493657 scopus 로고    scopus 로고
    • Adhesins and invasins of pathogenic bacteria: a structural view
    • Niemann, H.H., Schubert, W.D., Heinz, D.W., Adhesins and invasins of pathogenic bacteria: a structural view. Microbes Infect. 6 (2004), 101–112.
    • (2004) Microbes Infect. , vol.6 , pp. 101-112
    • Niemann, H.H.1    Schubert, W.D.2    Heinz, D.W.3
  • 57
    • 79960007606 scopus 로고    scopus 로고
    • Characterization of novel OmpA-like protein of Leptospira interrogans that binds extracellular matrix molecules and plasminogen
    • Oliveira, R., de Morais, Z.M., Goncales, A.P., Romero, E.C., Vasconcellos, S.A., Nascimento, A.L., Characterization of novel OmpA-like protein of Leptospira interrogans that binds extracellular matrix molecules and plasminogen. PloS One, 6, 2011, e21962.
    • (2011) PloS One , vol.6 , pp. e21962
    • Oliveira, R.1    de Morais, Z.M.2    Goncales, A.P.3    Romero, E.C.4    Vasconcellos, S.A.5    Nascimento, A.L.6
  • 60
    • 33644753762 scopus 로고    scopus 로고
    • Immunoprotection of recombinant leptospiral immunoglobulin-like protein A against Leptospira interrogans serovar Pomona infection
    • Palaniappan, R.U., McDonough, S.P., Divers, T.J., Chen, C.S., Pan, M.J., Matsumoto, M., Chang, Y.F., Immunoprotection of recombinant leptospiral immunoglobulin-like protein A against Leptospira interrogans serovar Pomona infection. Infect. Immun. 74 (2006), 1745–1750.
    • (2006) Infect. Immun. , vol.74 , pp. 1745-1750
    • Palaniappan, R.U.1    McDonough, S.P.2    Divers, T.J.3    Chen, C.S.4    Pan, M.J.5    Matsumoto, M.6    Chang, Y.F.7
  • 62
    • 78149244223 scopus 로고    scopus 로고
    • The OmpL37 surface-exposed protein is expressed by pathogenic Leptospira during infection and binds skin and vascular elastin
    • Pinne, M., Choy, H.A., Haake, D.A., The OmpL37 surface-exposed protein is expressed by pathogenic Leptospira during infection and binds skin and vascular elastin. PLoS Negl. Trop. Dis., 4, 2010, e815.
    • (2010) PLoS Negl. Trop. Dis. , vol.4 , pp. e815
    • Pinne, M.1    Choy, H.A.2    Haake, D.A.3
  • 63
    • 31144473639 scopus 로고    scopus 로고
    • Subversion of cellular functions by Listeria monocytogenes
    • Pizarro-Cerda, J., Cossart, P., Subversion of cellular functions by Listeria monocytogenes. J. Pathol. 208 (2006), 215–223.
    • (2006) J. Pathol. , vol.208 , pp. 215-223
    • Pizarro-Cerda, J.1    Cossart, P.2
  • 64
    • 0033833451 scopus 로고    scopus 로고
    • Overview of the epidemiology, microbiology, and pathogenesis of Leptospira spp. in humans
    • Plank, R., Dean, D., Overview of the epidemiology, microbiology, and pathogenesis of Leptospira spp. in humans. Microb. Infect. 2 (2000), 1265–1276.
    • (2000) Microb. Infect. , vol.2 , pp. 1265-1276
    • Plank, R.1    Dean, D.2
  • 67
    • 34447108853 scopus 로고    scopus 로고
    • Evaluation of different ways of presenting LipL32 to the immune system with the aim of developing a recombinant vaccine against leptospirosis
    • Seixas, F.K., Fernandes, C.H., Hartwig, D.D., Conceicao, F.R., Aleixo, J.A., Dellagostin, O.A., Evaluation of different ways of presenting LipL32 to the immune system with the aim of developing a recombinant vaccine against leptospirosis. Can. J. Microbiol. 53 (2007), 472–479.
    • (2007) Can. J. Microbiol. , vol.53 , pp. 472-479
    • Seixas, F.K.1    Fernandes, C.H.2    Hartwig, D.D.3    Conceicao, F.R.4    Aleixo, J.A.5    Dellagostin, O.A.6
  • 68
  • 69
    • 77958454595 scopus 로고    scopus 로고
    • Reverse vaccinology: developing vaccines in the era of genomics
    • Sette, A., Rappuoli, R., Reverse vaccinology: developing vaccines in the era of genomics. Immunity 33 (2010), 530–541.
    • (2010) Immunity , vol.33 , pp. 530-541
    • Sette, A.1    Rappuoli, R.2
  • 72
    • 84865199168 scopus 로고    scopus 로고
    • Lsa30, a novel adhesin of Leptospira interrogans binds human plasminogen and the complement regulator C4bp
    • Souza, N.M., Vieira, M.L., Alves, I.J., de Morais, Z.M., Vasconcellos, S.A., Nascimento, A.L., Lsa30, a novel adhesin of Leptospira interrogans binds human plasminogen and the complement regulator C4bp. Microb. Pathog. 53 (2012), 125–134.
    • (2012) Microb. Pathog. , vol.53 , pp. 125-134
    • Souza, N.M.1    Vieira, M.L.2    Alves, I.J.3    de Morais, Z.M.4    Vasconcellos, S.A.5    Nascimento, A.L.6
  • 74
    • 33746619204 scopus 로고    scopus 로고
    • The interaction between pathogens and the host coagulation system
    • Sun, H., The interaction between pathogens and the host coagulation system. Physiology (Bethesda, Md.) 21 (2006), 281–288.
    • (2006) Physiology (Bethesda, Md.) , vol.21 , pp. 281-288
    • Sun, H.1
  • 75
    • 84928911371 scopus 로고    scopus 로고
    • Features of two new proteins with OmpA-like domains identified in the genome sequences of Leptospira interrogans
    • Teixeira, A.F., de Morais, Z.M., Kirchgatter, K., Romero, E.C., Vasconcellos, S.A., Nascimento, A.L., Features of two new proteins with OmpA-like domains identified in the genome sequences of Leptospira interrogans. PLoS One, 10, 2015, e0122762.
    • (2015) PLoS One , vol.10 , pp. e0122762
    • Teixeira, A.F.1    de Morais, Z.M.2    Kirchgatter, K.3    Romero, E.C.4    Vasconcellos, S.A.5    Nascimento, A.L.6
  • 76
    • 77951239052 scopus 로고    scopus 로고
    • Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen
    • Verma, A., Brissette, C.A., Bowman, A.A., Shah, S.T., Zipfel, P.F., Stevenson, B., Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen. Infect. Immun. 78 (2010), 2053–2059.
    • (2010) Infect. Immun. , vol.78 , pp. 2053-2059
    • Verma, A.1    Brissette, C.A.2    Bowman, A.A.3    Shah, S.T.4    Zipfel, P.F.5    Stevenson, B.6
  • 79
    • 69049111014 scopus 로고    scopus 로고
    • Plasminogen acquisition and activation at the surface of leptospira species lead to fibronectin degradation
    • Vieira, M.L., Vasconcellos, S.A., Goncales, A.P., de Morais, Z.M., Nascimento, A.L., Plasminogen acquisition and activation at the surface of leptospira species lead to fibronectin degradation. Infect. Immun. 77 (2009), 4092–4101.
    • (2009) Infect. Immun. , vol.77 , pp. 4092-4101
    • Vieira, M.L.1    Vasconcellos, S.A.2    Goncales, A.P.3    de Morais, Z.M.4    Nascimento, A.L.5
  • 80
    • 80052427624 scopus 로고    scopus 로고
    • In vitro evidence for immune evasion activity by human plasmin associated to pathogenic Leptospira interrogans
    • Vieira, M.L., de Morais, Z.M., Vasconcellos, S.A., Romero, E.C., Nascimento, A.L., In vitro evidence for immune evasion activity by human plasmin associated to pathogenic Leptospira interrogans. Microb. Pathog. 51 (2013), 360–365.
    • (2013) Microb. Pathog. , vol.51 , pp. 360-365
    • Vieira, M.L.1    de Morais, Z.M.2    Vasconcellos, S.A.3    Romero, E.C.4    Nascimento, A.L.5
  • 84
    • 84928912610 scopus 로고    scopus 로고
    • Interaction of spirochetes with the host fibrinolytic system and potential roles in pathogenesis
    • Vieira, M.L., Nascimento, A.L., Interaction of spirochetes with the host fibrinolytic system and potential roles in pathogenesis. Crit. Rev. Microbiol., 2015, 1–15.
    • (2015) Crit. Rev. Microbiol. , pp. 1-15
    • Vieira, M.L.1    Nascimento, A.L.2
  • 87
    • 17444392120 scopus 로고    scopus 로고
    • Fibrinogen and fibrin
    • Weisel, J.W., Fibrinogen and fibrin. Adv. Protein Chem. 70 (2005), 247–299.
    • (2005) Adv. Protein Chem. , vol.70 , pp. 247-299
    • Weisel, J.W.1
  • 88
    • 77049125464 scopus 로고    scopus 로고
    • Identification and characterization of OmpA-like proteins as novel vaccine candidates for Leptospirosis
    • Yan, W., Faisal, S.M., McDonough, S.P., Chang, C.F., Pan, M.J., Akey, B., Chang, Y.F., Identification and characterization of OmpA-like proteins as novel vaccine candidates for Leptospirosis. Vaccine 28 (2010), 2277–2283.
    • (2010) Vaccine , vol.28 , pp. 2277-2283
    • Yan, W.1    Faisal, S.M.2    McDonough, S.P.3    Chang, C.F.4    Pan, M.J.5    Akey, B.6    Chang, Y.F.7
  • 89
    • 61449266273 scopus 로고    scopus 로고
    • Immunogenicity and protective efficacy of recombinant Leptospira immunoglobulin-like protein B (rLigB) in a hamster challenge model
    • Yan, W., Faisal, S.M., McDonough, S.P., Divers, T.J., Barr, S.C., Chang, C.F., Pan, M.J., Chang, Y.F., Immunogenicity and protective efficacy of recombinant Leptospira immunoglobulin-like protein B (rLigB) in a hamster challenge model. Microb. Infect. 11 (2009), 230–237.
    • (2009) Microb. Infect. , vol.11 , pp. 230-237
    • Yan, W.1    Faisal, S.M.2    McDonough, S.P.3    Divers, T.J.4    Barr, S.C.5    Chang, C.F.6    Pan, M.J.7    Chang, Y.F.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.