Identification of the hemolysis-associated protein 1 as a cross-protective immunogen of Leptospira interrogans by adenovirus-mediated vaccination

Infection and Immunity

Volumn 69, Issue 11, 2001, Pages 6831-6838

  Branger, C ^a   Sonrier, C ^a   Chatrenet, B ^a   Klonjkowski, B ^a   Ruvoen Clouet, N ^a   Aubert, A ^a   Andre Fontaine G ^a   Eloit, M ^a  

^a LUNAM UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; HEMOLYSIS ASSOCIATED PROTEIN 1; OUTER MEMBRANE PROTEIN; UNCLASSIFIED DRUG;

ADENOVIRUS; AMINO TERMINAL SEQUENCE; ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; GERBIL; LEPTOSPIRA INTERROGANS; LEPTOSPIROSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; PRIORITY JOURNAL; SOUTHERN BLOTTING; VACCINATION;

ADENOVIRIDAE; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BACTERIAL VACCINES; BASE SEQUENCE; CHEMICAL FRACTIONATION; CROSS REACTIONS; DNA, BACTERIAL; GENETIC VECTORS; GERBILLINAE; HEMOLYSIN PROTEINS; HEMOLYSIS; LEPTOSPIRA INTERROGANS; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; VACCINATION; VACCINES, SYNTHETIC; WEIL DISEASE;

EID: 0034778155     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.11.6831-6838.2001     Document Type: Article

References (37)

1. Isolation of the outer sheath of Leptospira and its immunogenic properties in hamsters
2. Scattering of the rRNA genes on the physical map of the circular chromosome of Leptospira interrogans serovar icterohaemorrhagiae
3. The significance of leptospiral hemolysin in the pathogenesis of Leptospira pomona infections
4. Estimating the costs associated with endemic disease of dairy cattle
5. Efficient generation of adenovirus vectors by homologous recombination in Escherchia coli
6. Nutrition of Leptospira pomona and growth of 13 other serotypes: Fractionation of oleic albumin complex and a medium of bovin albumin and polysorbate 80
7. Construction of a defective adenovirus vector expressing the pseudorabies virus glycoprotein gp50 and its use as a live vaccine
8. Leptospirosis
9. Immunoblotting study of the antigenic relationships among eight serogroups of Leptospira
10. Recognition of Leptospira interrogans antigens by vaccinated or infected dogs
11. Infertility and abortion among first-lactation dairy cows seropositive or seronegative for Leptospira interrogans serovar hardjo
12. Molecular cloning and sequence analysis of the gene encoding OmpL1, a transmembrane outer membrane protein of pathogenic Leptospira sp
13. Changes in the surface of Leptospira interrogans serovar grippotyphosa during in vitro cultivation
14. The leptospiral outer membrane protein LipL32 is a lipoprotein expressed during mammalian infection
15. Leptospiral outer membrane protein OmpL1 and LipL41 exhibit synergistic immunoprotection
16. Protective efficacy of an affinity-purified hemolysin vaccine against experimental swine pleuropneumonia
17. Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vector
18. Adenoviral vectors for vaccines
19. Urban epidemic of severe leptospirosis study in Brazil
20. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
21. Incidence of leptospiral abortion in Brazilian dairy cattle
22. Identification and partial characterization of a novel hemolysin from Leptospira interrogans serovar lai
23. Acute lung injury in leptospirosis: Clinical and laboratory features, outcomes, and factors associated with mortality
24. Swine leptospirosis: Low risk of exposure for humans?
25. Molecular analysis of a sphingomyelinase C gene from Leptospira interrogans serovar hardjo
26. The rare outer membrane protein, OmpL1, of pathogenic Leptospira species is a heat-modifiable porin
27. Stillbirth/perinatal weak calf syndrome: A study of calves infected with Leptospira
28. Evidence of cross-protection within Leptospira interrogans in an experimental model
29. In vitro studies of haemolysis by Leptospira interrogans serovar pomona and ballum
30. Epidemic leptospirosis associated with pulmonary hemorrhage - Nicaragua, 1995
31. Comparison of genetic maps for two Leptospira interrogans serovars provides evidence for two chromosomes and intraspecies heterogeneity
32. Characterization of outer membrane and secreted proteins of Leptospira interrogans serovar pomona