Immunoprotection of recombinant leptospiral immunoglobulin-like protein A against Leptospira interrogans serovar pomona infection

Infection and Immunity

Volumn 74, Issue 3, 2006, Pages 1745-1750

  Palaniappan, Raghavan U M ^a   McDonough, Sean P ^a   Divers, Thomas J ^a   Chen, Chia Sui ^a   Pan, Ming Jeng ^b   Matsumoto, Mitsuharu ^a   Chang, Yung Fu ^a  

^a Department of Obstetrics Gynecology   (United States)

^b CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT; ALUMINUM HYDROXIDE; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; IMMUNOGLOBULIN; LEPTOSPIRAL IMMUNOGLOBULIN LIKE PROTEIN; LEPTOSPIRAL IMMUNOGLOBULIN LIKE PROTEIN A; LEPTOSPIRAL IMMUNOGLOBULIN LIKE PROTEIN B; PHOSPHATE BUFFERED SALINE; PROTEIN A; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VACCINE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ESCHERICHIA COLI; GENETIC CONSERVATION; HAMSTER; HISTOPATHOLOGY; IMMUNITY; INTERSTITIAL NEPHRITIS; LEPTOSPIRA INTERROGANS; LEPTOSPIROSIS; LETHAL DOSE; MOLECULAR CLONING; NONHUMAN; PASSIVE IMMUNIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROVOCATION TEST; SEROTYPE; SURVIVAL RATE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, BACTERIAL; CRICETINAE; DISEASE MODELS, ANIMAL; IMMUNOGLOBULINS; KIDNEY; LEPTOSPIRA INTERROGANS SEROVAR POMONA; LEPTOSPIROSIS; RECOMBINANT PROTEINS; STAPHYLOCOCCAL PROTEIN A; VACCINES, SYNTHETIC;

EID: 33644753762     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.74.3.1745-1750.2006     Document Type: Article

References (39)

1. Adler, B., and S. Faine. 1976. Susceptibility of mice treated with cyclophosphamide to lethal infection with Leptospira interrogans serovar Pomona. Infect. Immun. 14:703-708.
2. Andre-Fontaine, G., C. Branger, A. W. Gray, and H. L. Klaasen. 2003. Comparison of the efficacy of three commercial bacterins in preventing canine leptospirosis. Vet. Rec. 153:165-169.
3. Bharti, A. R., J. E. Nally, J. N. Ricaldi, M. A. Matthias, M. M. Diaz, M. A. Lovett, P. N. Levett, R. H. Gilman, M. R. Willig, E. Gotuzzo, and J. M. Vinetz. 2003. Leptospirosis: a zoonotic disease of global importance. Lancet Infect. Dis. 3:757-771.
4. Bolin, C. A., and D. P. Alt. 2001. Use of a monovalent leptospiral vaccine to prevent renal colonization and urinary shedding in cattle exposed to Leptospira borgpetersenii serovar Hardjo. Am. J. Vet. Res. 62:995-1000.
5. Borer, A., I. Metz, J. Gilad, K. Riesenberg, N. Weksler, G. Weber, M. Alkan, and J. Horowitz. 1999. Massive pulmonary haemorrhage caused by leptospirosis successfully treated with nitric oxide inhalation and haemofiltration. J. Infect. 38:42-45.
6. Branger, C., B. Chatrenet, A. Gauvrit, F. Aviat, A. Aubert, J. M. Bach, and G. Andre-Fontaine. 2005. Protection against Leptospira interrogans sensu lato challenge by DNA immunization with the gene encoding hemolysin-associated protein 1. Infect. Immun. 73:4062-4069.
7. Branger, C., C. Sonrier, B. Chatrenet, B. Klonjkowski, N. Ruvoen-Clouet, A. Aubert, G. Andre-Fontaine, and M. Eloit. 2001. Identification of the hemolysis-associated protein 1 as a cross-protective immunogen of Leptospira interrogans by adenovirus-mediated vaccination. Infect. Immun. 69:6831-6838.
8. Brown, R. A., S. Blumerman, C. Gay, C. Bolin, R. Duby, and C. L. Baldwin. 2003. Comparison of three different leptospiral vaccines for induction of a type 1 immune response to Leptospira borgpetersenii serovar Hardjo. Vaccine 21:4448-4458.
9. Chang, Y., V. Novosol, S. P, McDonough, C. F. Chang, R. H. Jacobson, T. Divers, F. W. Quimby, S. Shin, and D. H. Lein. 1999. Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface protein A (rOspA) in horses. Vaccine 18:540-548.
10. Chang, Y. F., M. J. Appel, R. H. Jacobson, S. J. Shin, P. Harpending, R. Straubinger, L. A. Patrican, H. Mohammed, and B. A. Summers. 1995. Recombinant OspA protects dogs against infection and disease caused by Borrelia burgdorferi. Infect. Immun. 63:3543-3549.
11. Ciceroni, L., P. D'Aniello, N. Russo, D. Picarella, D. Nese, F. Lauria, A. Pinto, and B. Cacciapuoti. 1995. Prevalence of leptospire infections in buffalo herds in Italy. Vet. Rec. 137:192-193.
12. Ciceroni, L., A. Pinto, E. Benedetti, P. Pizzocaro, R. Lupidi, M. Cinco, L. Gelosa, R. Grille, V. Rondinella, L. Marcuccio, et al. 1995. Human leptospirosis in Italy, 1986-1993. Eur. J. Epidemiol. 11:707-710.
13. Cullen, P. A., D. A. Haake, D. M. Bulach, R. L. Zuerner, and B. Adler. 2003. LipL21 is a novel surface-exposed lipoprotein of pathogenic Leptospira species. Infect. Immun. 71:2414-2421.
14. Cullen, P. A., X. Xu, J. Matsunaga, Y. Sanchez, A. I. Ko, D. A. Haake, and B. Adler. 2005. Surfaceome of Leptospira spp. Infect. Immun. 73:4853-4863.
15. Davidson, M. G., M. P. Nasisse, and S. M. Roberts. 1987. Immunodiagnosis of leptospiral uveitis in two horses. Equine Vet. J. 19:155-157.
16. Donahue, J. M., B. J. Smith, K. B. Poonacha, J. K. Donahoe, and C. L. Rigsby. 1995. Prevalence and serovars of leptospira involved in equine abortions in central Kentucky during the 1991-1993 foaling seasons. J. Vet. Diagn. Investig. 7:87-91.
17. Donahue, J. M., B. J. Smith, K. J. Redmon, and J. K. Donahue. 1991. Diagnosis and prevalence of leptospira infection in aborted and stillborn horses. J. Vet. Diagn. Investig. 3:148-151.
18. Faine, S., B. Adher, C. Bloin, and P. Perolat. 1999. Leptospira and leptospirosis, 2nd ed. MedSci, Melbourne, Australia.
19. Haake, D. A. 2000. Spirochaetal lipoproteins and pathogenesis. Microbiology 146:1491-1504.
20. Haake, D. A., G. Chao, R. L. Zuerner, J. K. Barnett, D. Barnett, M. Mazel, J. Matsunaga, P. N. Levett, and C. A. Bolin. 2000. The leptospiral major outer membrane protein LipL32 is a lipoprotein expressed during mammalian infection. Infect. Immun. 68:2276-2285.
21. Haake, D. A., C. Martinich, T. A. Summers, E. S. Shang, J. D. Pruetz, A. M. McCoy, M. K. Mazel, and C. A. Bolin. 1998. Characterization of leptospiral outer membrane lipoprotein LipL36: downregulation associated with late-log-phase growth and mammalian infection. Infect. Immun. 66:1579-1587.
22. Haake, D. A., M. K. Mazel, A. M. McCoy, F. Milward, G. Chao, J. Matsunaga, and E. A. Wagar. 1999. Leptospiral outer membrane proteins OmpL1 and LipL41 exhibit synergistic immunoprotection. Infect. Immun. 67:6572-6582.
23. Kalsow, C. M., and A. E. Dwyer. 1998. Retinal immunopathology in horses with uveitis. Ocul. Immunol. Inflamm. 6:239-251.
24. Koizumi, N., and H. Watanabe. 2004. Leptospiral immunoglobulin-like proteins elicit protective immunity. Vaccine 22:1545-1552.
25. Levett, P. N. 2001. Leptospirosis. Clin. Microbiol. Rev. 14:296-326.
26. Matsunaga, J., M. A. Barocchi, J. Croda, T. A. Young, Y. Sanchez, I. Siqueira, C. A. Bolin, M. G. Reis, L. W. Riley, D. A. Haake, and A. I. Ko. 2003. Pathogenic Leptospira species express surface-exposed proteins belonging to the bacterial immunoglobulin superfamily. Mol. Microbiol. 49:929-945.
27. Matsunaga, J., Y. Sanchez, X. Xu, and D. A. Haake. 2005. Osmolarity, a key environmental signal controlling expression of leptospiral proteins LigA and LigB and the extracellular release of LigA. Infect. Immun. 73:70-78.
28. McBride, A. J., D. A. Athanazio, M. G. Reis, and A. I. Ko. 2005. Leptospirosis. Curr. Opin. Infect. Dis. 18:376-386.
29. Naiman, B. M., D. Alt, C. A. Bolin, R. Zuerner, and C. L. Baldwin. 2001. Protective killed Leptospira borgpetersenii vaccine induces potent Th1 immunity comprising responses by CD4 and 78 T lymphocytes. Infect. Immun. 69:7550-7558.
30. + γδ and CD4 T cells. Infect. Immun. 70:6147-6157.
31. Nally, J. E., M. C. Fishbein, D. R. Blanco, and M. A. Lovett. 2005. Lethal infection of C3H/HeJ and C3H/SCID mice with an isolate of Leptospira interrogans serovar Copenhageni. Infect. Immun. 73:7014-7017.
32. Nally, J. E., J. F. Timoney, and B. Stevenson. 2001. Temperature- regulated protein synthesis by Leptospira interrogans. Infect. Immun. 69:400-404.
33. Palaniappan, R. U., Y. F. Chang, F. Hassan, S. P. McDonough, M. Pough, S. C. Barr, K. W. Simpson, H. O. Mohammed, S. Shin, P. McDonough, R. L. Zuerner, J. Qu, and B. Roe. 2004. Expression of leptospiral immunoglobulin-like protein by Leptospira interrogans and evaluation of its diagnostic potential in a kinetic ELISA. J. Med. Microbiol. 53:975-984.
34. Palaniappan, R. U., Y. F. Chang, S. S. Jusuf, S. Artiushin, J. F. Timoney, S. P. McDonough, S. C. Barr, T. J. Divers, K. W. Simpson, P. L. McDonough, and H. O. Mohammed. 2002. Cloning and molecular characterization of an immunogenic LigA protein of Leptospira interrogans. Infect. Immun. 70:5924-5930.
35. Parma, A. E., M. E. Sanz, P. M. Lucchesi, J. Mazzonelli, and M. A. Petruccelli. 1997. Detection of an antigenic protein of Leptospira interrogans which shares epitopes with the equine cornea and lens. Vet. J. 153:75-79.
36. Shang, E. S., M. M. Exner, T. A. Summers, C. Martinich, C. I. Champion, R. E. Hancock, and D. A. Haake. 1995. The rare outer membrane protein, OmpL1, of pathogenic Leptospira species is a heat-modifiable porin. Infect. Immun. 63:3174-3181.
37. Smyth, J. A., D. A. Fitzpatrick, and W. A. Ellis. 1999. Stillbirth/perinatal weak calf syndrome: a study of calves infected with Leptospira. Vet. Rec. 145:539-542.
38. Thiermann, A. B. 1984. Leptospirosis: current developments and trends. J. Am. Vet. Med. Assoc. 184:722-725.
39. Yip, Y. L., G. Smith, and R. L. Ward. 2001. Comparison of phage pIII, pVIII and GST as carrier proteins for peptide immunisation in BALB/c mice. Immunol. Lett. 79:197-202.