Molecular insights into the OGG1 gene, a cancer risk modifier in BRCA1 and BRCA2 mutations carriers

Oncotarget

Volumn 7, Issue 18, 2016, Pages 25815-25825

  Benitez Buelga, Carlos ^a   Vaclová, Tereza ^a   Ferreira, Sofia ^a   Urioste, Miguel ^a,b   Inglada Perez, Lucia ^a,b   Soberón, Nora ^a   Blasco, Maria A ^a   Osorio, Ana ^a,b   Benitez, Javier ^a,b  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

Author keywords

BRCA1 and BRCA2; Cancer risk modifier; DNA damage; OGG1 polymorfism; Telomere shortening

Indexed keywords

8 GUANINE DNA GLYCOSYLASE; BRCA1 PROTEIN; BRCA2 PROTEIN; DNA; DNA GLYCOSYLTRANSFERASE; MESSENGER RNA; UNCLASSIFIED DRUG; BRCA1 PROTEIN, HUMAN; BRCA2 PROTEIN, HUMAN; OXOGUANINE GLYCOSYLASE 1, HUMAN;

ARTICLE; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOMIC INSTABILITY; GENOTYPE; GENOTYPE PHENOTYPE CORRELATION; HETEROZYGOTE; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; MAJOR CLINICAL STUDY; MUTATION RATE; OGG1 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; TELOMERE HOMEOSTASIS; TELOMERE SHORTENING; TRANSCRIPTION REGULATION; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; MUTATION; OVARY TUMOR; RISK FACTOR;

BRCA1 PROTEIN; BRCA2 PROTEIN; DNA GLYCOSYLASES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MUTATION; OVARIAN NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84967138138     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.8272     Document Type: Article

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