Oxidative stress induces persistent telomeric DNA damage responsible for nuclear morphology change in mammalian cells

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Coluzzi, Elisa ^a   Colamartino, Monica ^a   Cozzi, Renata ^a   Leone, Stefano ^a   Meneghini, Carlo ^a   O'Callaghan, Nathan ^b   Sgura, Antonella ^a  

^a ROMA TRE UNIVERSITY   (Italy)

^b CSIRO   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE;

ARTICLE; CELL STRUCTURE; CHROMOSOMAL INSTABILITY; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MAMMAL CELL; MICRONUCLEUS; NUCLEAR BUD; NUCLEOPLASMIC BRIDGE; OXIDATIVE STRESS; REAL TIME POLYMERASE CHAIN REACTION; TELOMERE HOMEOSTASIS; TELOMERE SHORTENING; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; CELL LINE; CELL NUCLEUS; DRUG EFFECTS; GENETICS; METABOLISM; TELOMERE;

MAMMALIA;

CELL LINE; CELL NUCLEUS; CHROMOSOMAL INSTABILITY; DNA DAMAGE; HUMANS; HYDROGEN PEROXIDE; OXIDATIVE STRESS; TELOMERE; TELOMERE SHORTENING;

EID: 84908562971     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0110963     Document Type: Article

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