Stabilising cubosomes with Tween 80 as a step towards targeting lipid nanocarriers to the blood-brain barrier

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 104, Issue , 2016, Pages 148-155

  Azhari, Hanisah ^a   Strauss, Mike ^b   Hook, Sarah ^a   Boyd, Ben J ^c   Rizwan, Shakila B ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c MONASH UNIVERSITY   (Australia)

Author keywords

Blood brain barrier; Cryogenic electron tomography (cryo ET); Cubosomes; Phytantriol; Pluronic F127; Tween 80

Indexed keywords

CUBOSOME; NANOCARRIER; PHYTANTRIOL; POLOXAMER; POLYOL; POLYSORBATE 80; UNCLASSIFIED DRUG; WATER; DRUG CARRIER; LIPID; NANOPARTICLE; POLYSORBATE;

ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DISPERSION; DRUG TARGETING; ELECTRON TOMOGRAPHY; FOURIER TRANSFORMATION; MACROMOLECULE; MOLECULAR STABILITY; PARTICLE SIZE; PHOTON CORRELATION SPECTROSCOPY; POLARIZATION MICROSCOPY; SURFACE AREA; WATER CONTENT; X RAY CRYSTALLOGRAPHY; CHEMISTRY;

BLOOD-BRAIN BARRIER; DRUG CARRIERS; LIPIDS; NANOPARTICLES; POLYSORBATES;

EID: 84967104243     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2016.05.001     Document Type: Article

References (48)

1. W. Pardridge The blood-brain barrier: bottleneck in brain drug development NeuroRx 2 2005 3 14
2. W.M. Pardridge Drug transport across the blood-brain barrier J. Cereb. Blood Flow Metab. 32 2012 1959 1972
3. BDNF Study Group A controlled trial of recombinant methionyl human BDNF in ALS Neurology 52 1999 1427
4. R.G. Miller, J.H. Petajan, W.W. Bryan, C. Armon, R.J. Barohn, J.C. Goodpasture, R.J. Hoagland, G.J. Parry, M.A. Ross, and S.C. Stromatt A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis Ann. Neurol. 39 1996 256 260
5. J. Nutt, K. Burchiel, C. Comella, J. Jankovic, A. Lang, E. Laws, A. Lozano, R. Penn, R. Simpson, and M. Stacy Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD Neurology 60 2003 69 73
6. B. Vellas, M.C. Carrillo, C. Sampaio, H.R. Brashear, E. Siemers, H. Hampel, L.S. Schneider, M. Weiner, R. Doody, and Z. Khachaturian Designing drug trials for Alzheimer's disease: what we have learned from the release of the phase III antibody trials: a report from the EU/US/CTAD task force Alzheimer's Dementia 9 2013 438 444
7. H. Ehrenreich, K. Weissenborn, H. Prange, D. Schneider, C. Weimar, K. Wartenberg, P.D. Schellinger, M. Bohn, H. Becker, and M. Wegrzyn Recombinant human erythropoietin in the treatment of acute ischemic stroke Stroke 40 2009 e647 e656
8. J.V. Georgieva, D. Hoekstra, and I.S. Zuhorn Smuggling drugs into the brain: an overview of ligands targeting transcytosis for drug delivery across the blood-brain barrier Pharmaceutics 6 2014 557 583
9. M. Srikanth, and J.A. Kessler Nanotechnology - novel therapeutics for CNS disorders Nat. Rev. Neurol. 8 2012 307 318
10. J. Kreuter, P. Ramge, V. Petrov, S. Hamm, S. Gelperina, B. Engelhardt, R. Alyautdin, H. von Briesen, and D. Begley Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles Pharm. Res. 20 2003 409 416
11. J. Kreuter, D. Shamenkov, V. Petrov, P. Ramge, K. Cychutek, C. Koch-Brandt, and R. Alyautdin Apolipoprotein-mediated transport of nanoparticle-bound drugs across the blood-brain barrier J. Drug Targeting 10 2002 317 325
12. S.B. Rizwan, D. Assmus, A. Boehnke, T. Hanley, B.J. Boyd, T. Rades, and S. Hook Preparation of phytantriol cubosomes by solvent precursor dilution for the delivery of protein vaccines Eur. J. Pharm. Biopharm. 79 2011 15 22
13. S.B. Rizwan, Y. Dong, B.J. Boyd, T. Rades, and S. Hook Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM) Micron 38 2007 478 485
14. S.B. Rizwan, T. Hanley, B.J. Boyd, and S. Hook Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: characterisation, swelling and release kinetics J. Pharm. Sci. 98 2009 4191 4204
15. S.B. Rizwan, W.T. McBurney, K. Young, T. Hanley, B.J. Boyd, T. Rades, and S. Hook Cubosomes containing the adjuvants imiquimod and monophosphoryl lipid A stimulate robust cellular and humoral immune responses J. Controlled Release 165 2013 16 21
16. R.N. Alyaudtin, A. Reichel, R. Löbenberg, P. Ramge, J. Kreuter, and D.J. Begley Interaction of poly (butylcyanoacrylate) nanoparticles with the blood-brain barrier in vivo and in vitro J. Drug Targeting 9 2001 209 221
17. J. Kreuter, T. Hekmatara, S. Dreis, T. Vogel, S. Gelperina, and K. Langer Covalent attachment of apolipoprotein AI and apolipoprotein B-100 to albumin nanoparticles enables drug transport into the brain J. Controlled Release 118 2007 54 58
18. J. Kreuter Mechanism of polymeric nanoparticle-based drug transport across the blood-brain barrier (BBB) J. Microencaps. 30 2013 49 54
19. K. Michaelis, M.M. Hoffmann, S. Dreis, E. Herbert, R.N. Alyautdin, M. Michaelis, J. Kreuter, and K. Langer Covalent linkage of apolipoprotein e to albumin nanoparticles strongly enhances drug transport into the brain J. Pharmacol. Exp. Ther. 317 2006 1246 1253
20. S. Wagner, A. Zensi, S.L. Wien, S.E. Tschickardt, W. Maier, T. Vogel, F. Worek, C.U. Pietrzik, J. Kreuter, and H. Von Briesen Uptake mechanism of ApoE-modified nanoparticles on brain capillary endothelial cells as a blood-brain barrier model PLoS ONE 7 2012 e32568
21. J. Barauskas, C. Cervin, M. Jankunec, M. Špandyreva, K. Ribokaite, F. Tiberg, and M. Johnsson Interactions of lipid-based liquid crystalline nanoparticles with model and cell membranes Int. J. Pharm. 391 2010 284 291
22. J. Barauskas, A. Misiunas, T. Gunnarsson, F. Tiberg, and M. Johnsson "Sponge" nanoparticle dispersions in aqueous mixtures of diglycerol monooleate, glycerol dioleate, and polysorbate 80 Langmuir 22 2006 6328 6334
23. F.B. Rosevear The microscopy of the liquid crystalline neat and middle phases of soaps and synthetic detergents J. Am. Oil Chem. Soc. 31 1954 628 639
24. N.M. Kirby, S.T. Mudie, A.M. Hawley, D.J. Cookson, H.D. Mertens, N. Cowieson, and V. Samardzic-Boban A low-background-intensity focusing small-angle X-ray scattering undulator beamline J. Appl. Crystallogr. 46 2013 1670 1680
25. S. Hyde Identification of lyotropic liquid crystal mesophases K. Holmberg, Handb. Appl. Surf. Colloid Chem. 2001 John Wiley & Sons Ltd. 299 331 (Chapter 16)
26. D.N. Mastronarde Automated electron microscope tomography using robust prediction of specimen movements J. Struct. Biol. 152 2005 36 51
27. J.R. Kremer, D.N. Mastronarde, and J.R. McIntosh Computer visualization of three-dimensional image data using IMOD J. Struct. Biol. 116 1996 71 76
28. A.S. Frangakis, and R. Hegerl Noise reduction in electron tomographic reconstructions using nonlinear anisotropic diffusion J. Struct. Biol. 135 2001 239 250
29. E.F. Pettersen, T.D. Goddard, C.C. Huang, G.S. Couch, D.M. Greenblatt, E.C. Meng, and T.E. Ferrin UCSF Chimera - a visualization system for exploratory research and analysis J. Comput. Chem. 25 2004 1605 1612
30. J.Y.T. Chong, X. Mulet, L.J. Waddington, B.J. Boyd, and C.J. Drummond Steric stabilisation of self-assembled cubic lyotropic liquid crystalline nanoparticles: high throughput evaluation of triblock polyethylene oxide-polypropylene oxide-polyethylene oxide copolymers Soft Matter 7 2011 4768 4777
31. Y. Dong, I. Larson, T. Hanley, and B.J. Boyd Bulk and dispersed aqueous phase behavior of phytantriol: effect of vitamin E acetate and F127 polymer on liquid crystal structure Langmuir 22 2006 9512 9518
32. J. Gustafsson, H. Ljusberg - Wahren, M. Almgren, and K. Larsson Cubic lipid-water phase dispersed into submicron particles Langmuir 12 1996 4611 4613
33. J. Gustafsson, H. Ljusberg-Wahren, M. Almgren, and K. Larsson Submicron particles of reversed lipid phases in water stabilized by a nonionic amphiphilic polymer Langmuir 13 1997 6964 6971
34. W.A. Banks Drug delivery to the brain in Alzheimer's disease: consideration of the blood-brain barrier Adv. Drug Delivery Rev. 64 2012 629 639
35. N. Abbott, L. Ronnback, and E. Hansson Astrocyte-endothelial interactions at the blood-brain barrier Nat. Rev. Neurosci. 7 2006 41 53
36. M. Yemisci, S. Caban, Y. Gursoy-Ozdemir, S. Lule, R. Novoa-Carballal, R. Riguera, E. Fernandez-Megia, K. Andrieux, P. Couvreur, and Y. Capan Systemically administered brain-targeted nanoparticles transport peptides across the blood-brain barrier and provide neuroprotection J. Cereb. Blood Flow Metab. 2014
37. M.V. Gidwani, and A. Singh Nanoparticle enabled drug delivery across the blood brain barrier: in vivo and in vitro models, opportunities and challenges Curr. Pharm. Biotechnol. 14 2013 1201 1212
38. R. Rempe, S. Cramer, R. Qiao, and H.-J. Galla Strategies to overcome the barrier: use of nanoparticles as carriers and modulators of barrier properties Cell Tissue Res. 355 2014 717 726
39. Y. Dong, A. Dong, I. Larson, M. Rappolt, H. Amenitsch, T. Hanley, and B.J. Boyd Impurities in commercial phytantriol significantly alter its lyotropic liquid-crystalline phase behavior Langmuir 24 2008 6998 7003
40. J.Y. Chong, X. Mulet, A. Postma, D.J. Keddie, L.J. Waddington, B.J. Boyd, and C.J. Drummond Novel RAFT amphiphilic brush copolymer steric stabilisers for cubosomes: poly (octadecyl acrylate)-block-poly (polyethylene glycol methyl ether acrylate) Soft Matter 10 2014 6666 6676
41. D. Demurtas, P. Guichard, I. Martiel, R. Mezzenga, C. Hebert, and L. Sagalowicz Direct visualization of dispersed lipid bicontinuous cubic phases by cryo-electron tomography Nat. Commun. 6 2015
42. J.Y. Chong, X. Mulet, L.J. Waddington, B.J. Boyd, and C.J. Drummond High-throughput discovery of novel steric stabilizers for cubic lyotropic liquid crystal nanoparticle dispersions Langmuir 28 2012 9223 9232
43. J. Barauskas, M. Johnsson, F. Joabsson, and F. Tiberg Cubic phase nanoparticles (cubosome): principles for controlling size, structure, and stability Langmuir 21 2005 2569 2577
44. M. Nakano, T. Teshigawara, A. Sugita, W. Leesajakul, A. Taniguchi, T. Kamo, H. Matsuoka, and T. Handa Dispersions of liquid crystalline phases of the monoolein/oleic acid/pluronic F127 system Langmuir 18 2002 9283 9288
45. A.J. Tilley, C.J. Drummond, and B.J. Boyd Disposition and association of the steric stabilizer Pluronic® F127 in lyotropic liquid crystalline nanostructured particle dispersions J. Colloid Interface Sci. 392 2013 288 296
46. R. Mezzenga, M. Grigorov, Z. Zhang, C. Servais, L. Sagalowicz, A.I. Romoscanu, V. Khanna, and C. Meyer Polysaccharide-induced order-to-order transitions in lyotropic liquid crystals Langmuir 21 2005 6165 6169
47. Q. Liu, Y.-D. Dong, T.L. Hanley, and B.J. Boyd Sensitivity of nanostructure in charged cubosomes to phase changes triggered by ionic species in solution Langmuir 29 2013 14265 14273
48. T.-H. Nguyen, T. Hanley, C.J.H. Porter, and B.J. Boyd Nanostructured liquid crystalline particles provide long duration sustained-release effect for a poorly water soluble drug after oral administration J. Controlled Release 153 2011 180 186