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Volumn 62, Issue 4, 2016, Pages 479-490

U2AF35(S34F) Promotes Transformation by Directing Aberrant ATG7 Pre-mRNA 3' End Formation

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AUTOPHAGY RELATED FACTOR 7 PROTEIN; AZACITIDINE; ETOPOSIDE; INTERLEUKIN 3; MESSENGER RNA PRECURSOR; PROTEIN; PROTEIN P62; TOPOTECAN; UNCLASSIFIED DRUG; ATG7 PROTEIN, HUMAN; ATG7 PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN 7; MESSENGER RNA; RNA PRECURSOR; SPLICING FACTOR U2AF; U2AF1 PROTEIN, HUMAN; U2AF1 PROTEIN, MOUSE;

EID: 84966660727     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.04.011     Document Type: Article
Times cited : (110)

References (54)
  • 1
    • 84867868500 scopus 로고    scopus 로고
    • Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements
    • Barrett L.W., Fletcher S., Wilton S.D. Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements. Cell. Mol. Life Sci. 2012, 69:3613-3634.
    • (2012) Cell. Mol. Life Sci. , vol.69 , pp. 3613-3634
    • Barrett, L.W.1    Fletcher, S.2    Wilton, S.D.3
  • 4
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human Networkbreast tumours
    • Cancer Genome Atlas Network
    • Comprehensive molecular portraits of human Networkbreast tumours. Nature 2012, 490:61-70. Cancer Genome Atlas Network.
    • (2012) Nature , vol.490 , pp. 61-70
  • 5
    • 84878372012 scopus 로고    scopus 로고
    • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
    • Cancer Genome Atlas Research Network
    • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N. Engl. J. Med. 2013, 368:2059-2074. Cancer Genome Atlas Research Network.
    • (2013) N. Engl. J. Med. , vol.368 , pp. 2059-2074
  • 6
    • 84872303004 scopus 로고    scopus 로고
    • Biologic and clinical significance of somatic mutations of SF3B1 in myeloid and lymphoid neoplasms
    • Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative
    • Cazzola M., Rossi M., Malcovati L. Biologic and clinical significance of somatic mutations of SF3B1 in myeloid and lymphoid neoplasms. Blood 2013, 121:260-269. Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative.
    • (2013) Blood , vol.121 , pp. 260-269
    • Cazzola, M.1    Rossi, M.2    Malcovati, L.3
  • 7
    • 0001044842 scopus 로고
    • Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein
    • Daley G.Q., Baltimore D. Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein. Proc. Natl. Acad. Sci. USA 1988, 85:9312-9316.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 9312-9316
    • Daley, G.Q.1    Baltimore, D.2
  • 8
    • 0034331199 scopus 로고    scopus 로고
    • Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors
    • de Vries H., Rüegsegger U., Hübner W., Friedlein A., Langen H., Keller W. Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. EMBO J. 2000, 19:5895-5904.
    • (2000) EMBO J. , vol.19 , pp. 5895-5904
    • de Vries, H.1    Rüegsegger, U.2    Hübner, W.3    Friedlein, A.4    Langen, H.5    Keller, W.6
  • 9
    • 84879408529 scopus 로고    scopus 로고
    • Alternative cleavage and polyadenylation: extent, regulation and function
    • Elkon R., Ugalde A.P., Agami R. Alternative cleavage and polyadenylation: extent, regulation and function. Nat. Rev. Genet. 2013, 14:496-506.
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 496-506
    • Elkon, R.1    Ugalde, A.P.2    Agami, R.3
  • 12
    • 78650448754 scopus 로고    scopus 로고
    • Chemical modulators of autophagy as biological probes and potential therapeutics
    • Fleming A., Noda T., Yoshimori T., Rubinsztein D.C. Chemical modulators of autophagy as biological probes and potential therapeutics. Nat. Chem. Biol. 2011, 7:9-17.
    • (2011) Nat. Chem. Biol. , vol.7 , pp. 9-17
    • Fleming, A.1    Noda, T.2    Yoshimori, T.3    Rubinsztein, D.C.4
  • 13
    • 79955554179 scopus 로고    scopus 로고
    • Differential genome-wide profiling of tandem 3' UTRs among human breast cancer and normal cells by high-throughput sequencing
    • Fu Y., Sun Y., Li Y., Li J., Rao X., Chen C., Xu A. Differential genome-wide profiling of tandem 3' UTRs among human breast cancer and normal cells by high-throughput sequencing. Genome Res. 2011, 21:741-747.
    • (2011) Genome Res. , vol.21 , pp. 741-747
    • Fu, Y.1    Sun, Y.2    Li, Y.3    Li, J.4    Rao, X.5    Chen, C.6    Xu, A.7
  • 15
    • 84903882101 scopus 로고    scopus 로고
    • An autophagic switch in the response of tumor cells to radiation and chemotherapy
    • Gewirtz D.A. An autophagic switch in the response of tumor cells to radiation and chemotherapy. Biochem. Pharmacol. 2014, 90:208-211.
    • (2014) Biochem. Pharmacol. , vol.90 , pp. 208-211
    • Gewirtz, D.A.1
  • 17
    • 84875175052 scopus 로고    scopus 로고
    • Cleavage factor Im is a key regulator of 3' UTR length
    • Gruber A.R., Martin G., Keller W., Zavolan M. Cleavage factor Im is a key regulator of 3' UTR length. RNA Biol. 2012, 9:1405-1412.
    • (2012) RNA Biol. , vol.9 , pp. 1405-1412
    • Gruber, A.R.1    Martin, G.2    Keller, W.3    Zavolan, M.4
  • 20
    • 66049104920 scopus 로고    scopus 로고
    • Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development
    • Ji Z., Lee J.Y., Pan Z., Jiang B., Tian B. Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development. Proc. Natl. Acad. Sci. USA 2009, 106:7028-7033.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 7028-7033
    • Ji, Z.1    Lee, J.Y.2    Pan, Z.3    Jiang, B.4    Tian, B.5
  • 22
  • 25
    • 84930506414 scopus 로고    scopus 로고
    • Identification of U2AF(35)-dependent exons by RNA-seq reveals a link between 3' splice-site organization and activity of U2AF-related proteins
    • Kralovicova J., Knut M., Cross N.C., Vorechovsky I. Identification of U2AF(35)-dependent exons by RNA-seq reveals a link between 3' splice-site organization and activity of U2AF-related proteins. Nucleic Acids Res. 2015, 43:3747-3763.
    • (2015) Nucleic Acids Res. , vol.43 , pp. 3747-3763
    • Kralovicova, J.1    Knut, M.2    Cross, N.C.3    Vorechovsky, I.4
  • 26
    • 84884693919 scopus 로고    scopus 로고
    • Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma
    • 202ra123
    • Liu H., He Z., von Rütte T., Yousefi S., Hunger R.E., Simon H.U. Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Sci. Transl. Med. 2013, 5:202ra123.
    • (2013) Sci. Transl. Med. , vol.5
    • Liu, H.1    He, Z.2    von Rütte, T.3    Yousefi, S.4    Hunger, R.E.5    Simon, H.U.6
  • 31
    • 34548096175 scopus 로고    scopus 로고
    • Why sick cells produce tumors: the protective role of autophagy
    • Mathew R., White E. Why sick cells produce tumors: the protective role of autophagy. Autophagy 2007, 3:502-505.
    • (2007) Autophagy , vol.3 , pp. 502-505
    • Mathew, R.1    White, E.2
  • 33
    • 68749113985 scopus 로고    scopus 로고
    • Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
    • Mayr C., Bartel D.P. Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 2009, 138:673-684.
    • (2009) Cell , vol.138 , pp. 673-684
    • Mayr, C.1    Bartel, D.P.2
  • 34
    • 33750200773 scopus 로고    scopus 로고
    • An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries
    • Millevoi S., Loulergue C., Dettwiler S., Karaa S.Z., Keller W., Antoniou M., Vagner S. An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries. EMBO J. 2006, 25:4854-4864.
    • (2006) EMBO J. , vol.25 , pp. 4854-4864
    • Millevoi, S.1    Loulergue, C.2    Dettwiler, S.3    Karaa, S.Z.4    Keller, W.5    Antoniou, M.6    Vagner, S.7
  • 35
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • Mizushima N., Yoshimori T. How to interpret LC3 immunoblotting. Autophagy 2007, 3:542-545.
    • (2007) Autophagy , vol.3 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 36
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N., Yoshimori T., Levine B. Methods in mammalian autophagy research. Cell 2010, 140:313-326.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 39
    • 0032827418 scopus 로고    scopus 로고
    • The protein kinase Clk/Sty directly modulates SR protein activity: both hyper- and hypophosphorylation inhibit splicing
    • Prasad J., Colwill K., Pawson T., Manley J.L. The protein kinase Clk/Sty directly modulates SR protein activity: both hyper- and hypophosphorylation inhibit splicing. Mol. Cell. Biol. 1999, 19:6991-7000.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 6991-7000
    • Prasad, J.1    Colwill, K.2    Pawson, T.3    Manley, J.L.4
  • 41
  • 43
    • 84869765539 scopus 로고    scopus 로고
    • Alternative polyadenylation: new insights from global analyses
    • Shi Y. Alternative polyadenylation: new insights from global analyses. RNA 2012, 18:2105-2117.
    • (2012) RNA , vol.18 , pp. 2105-2117
    • Shi, Y.1
  • 47
    • 0034008058 scopus 로고    scopus 로고
    • The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3'-end processing and splicing
    • Vagner S., Vagner C., Mattaj I.W. The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3'-end processing and splicing. Genes Dev. 2000, 14:403-413.
    • (2000) Genes Dev. , vol.14 , pp. 403-413
    • Vagner, S.1    Vagner, C.2    Mattaj, I.W.3
  • 48
    • 84871236747 scopus 로고    scopus 로고
    • Emerging roles of the spliceosomal machinery in myelodysplastic syndromes and other hematological disorders
    • Visconte V., Makishima H., Maciejewski J.P., Tiu R.V. Emerging roles of the spliceosomal machinery in myelodysplastic syndromes and other hematological disorders. Leukemia 2012, 26:2447-2454.
    • (2012) Leukemia , vol.26 , pp. 2447-2454
    • Visconte, V.1    Makishima, H.2    Maciejewski, J.P.3    Tiu, R.V.4
  • 50
    • 79957901938 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of myelodysplastic syndrome and acute myeloid leukemia
    • Watson A.S., Mortensen M., Simon A.K. Autophagy in the pathogenesis of myelodysplastic syndrome and acute myeloid leukemia. Cell Cycle 2011, 10:1719-1725.
    • (2011) Cell Cycle , vol.10 , pp. 1719-1725
    • Watson, A.S.1    Mortensen, M.2    Simon, A.K.3
  • 52
    • 0024408832 scopus 로고
    • Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor
    • Zamore P.D., Green M.R. Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor. Proc. Natl. Acad. Sci. USA 1989, 86:9243-9247.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9243-9247
    • Zamore, P.D.1    Green, M.R.2
  • 53
    • 67650230871 scopus 로고    scopus 로고
    • Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation
    • Zhang J., Randall M.S., Loyd M.R., Dorsey F.C., Kundu M., Cleveland J.L., Ney P.A. Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation. Blood 2009, 114:157-164.
    • (2009) Blood , vol.114 , pp. 157-164
    • Zhang, J.1    Randall, M.S.2    Loyd, M.R.3    Dorsey, F.C.4    Kundu, M.5    Cleveland, J.L.6    Ney, P.A.7
  • 54
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • Zhou R., Yazdi A.S., Menu P., Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011, 469:221-225.
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.