-
1
-
-
60349104299
-
The spliceosome: Design principles of a dynamic RNP machine
-
Wahl, M.C., Will, C.L. &Luhrmann, R. The spliceosome: design principles of a dynamic RNP machine. Cell 136, 701-718 (2009).
-
(2009)
Cell
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.L.2
Luhrmann, R.3
-
2
-
-
0026569967
-
Cloning and domain structure of the mammalian splicing factor U2AF
-
Zamore, P.D., Patton, J.G. &Green, M.R. Cloning and domain structure of the mammalian splicing factor U2AF. Nature 355, 609-614 (1992).
-
(1992)
Nature
, vol.355
, pp. 609-614
-
-
Zamore, P.D.1
Patton, J.G.2
Green, M.R.3
-
3
-
-
0026649523
-
Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit
-
Zhang, M., Zamore, P.D., Carmo-Fonseca, M., Lamond, A.I. &Green, M.R. Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit. Proc. Natl. Acad. Sci. USA 89, 8769-8773 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 8769-8773
-
-
Zhang, M.1
Zamore, P.D.2
Carmo-Fonseca, M.3
Lamond, A.I.4
Green, M.R.5
-
4
-
-
0029055472
-
Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins
-
Singh, R., Valcarcel, J. &Green, M.R. Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins. Science 268, 1173-1176 (1995).
-
(1995)
Science
, vol.268
, pp. 1173-1176
-
-
Singh, R.1
Valcarcel, J.2
Green, M.R.3
-
5
-
-
0030595187
-
Interaction of U2AF65 RS region with pre-mRNA branch point and promotion of base pairing with U2 snRNA
-
Valcrcel, J., Gaur, R.K., Singh, R. &Green, M.R. Interaction of U2AF65 RS region with pre-mRNA branch point and promotion of base pairing with U2 snRNA. Science 273, 1706-1709 (1996).
-
(1996)
Science
, vol.273
, pp. 1706-1709
-
-
Valcrcel, J.1
Gaur, R.K.2
Singh, R.3
Green, M.R.4
-
6
-
-
0028273768
-
The yeast MUD2 protein: An interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition
-
Abovich, N., Liao, X.C. &Rosbash, M. The yeast MUD2 protein: an interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition. Genes Dev. 8, 843-854 (1994).
-
(1994)
Genes Dev
, vol.8
, pp. 843-854
-
-
Abovich, N.1
Liao, X.C.2
Rosbash, M.3
-
7
-
-
0030911051
-
Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals
-
Abovich, N. &Rosbash, M. Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals. Cell 89, 403-412 (1997).
-
(1997)
Cell
, vol.89
, pp. 403-412
-
-
Abovich, N.1
Rosbash, M.2
-
8
-
-
79251571755
-
Genomic mRNA profiling reveals compensatory mechanisms for the requirement of the essential splicing factor U2AF
-
Sridharan, V., Heimiller, J. &Singh, R. Genomic mRNA profiling reveals compensatory mechanisms for the requirement of the essential splicing factor U2AF. Mol. Cell. Biol. 31, 652-661 (2011).
-
(2011)
Mol. Cell. Biol
, vol.31
, pp. 652-661
-
-
Sridharan, V.1
Heimiller, J.2
Singh, R.3
-
9
-
-
35148880587
-
A conditional role of U2AF in splicing of introns with unconventional polypyrimidine tracts
-
Sridharan, V. &Singh, R. A conditional role of U2AF in splicing of introns with unconventional polypyrimidine tracts. Mol. Cell. Biol. 27, 7334-7344 (2007).
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 7334-7344
-
-
Sridharan, V.1
Singh, R.2
-
10
-
-
0031013878
-
SC35-mediated reconstitution of splicing in U2AF-depleted nuclear extract
-
MacMillan, A.M., McCaw, P.S., Crispino, J.D. &Sharp, P.A. SC35-mediated reconstitution of splicing in U2AF-depleted nuclear extract. Proc. Natl. Acad. Sci. USA 94, 133-136 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 133-136
-
-
Macmillan, A.M.1
McCaw, P.S.2
Crispino, J.D.3
Sharp, P.A.4
-
11
-
-
0027437244
-
Novel nuclear autoantigen with splicing factor motifs identified with antibody from hepatocellular carcinoma
-
Imai, H., Chan, E.K., Kiyosawa, K., Fu, X.D. &Tan, E.M. Novel nuclear autoantigen with splicing factor motifs identified with antibody from hepatocellular carcinoma. J. Clin. Invest. 92, 2419-2426 (1993).
-
(1993)
J. Clin. Invest
, vol.92
, pp. 2419-2426
-
-
Imai, H.1
Chan, E.K.2
Kiyosawa, K.3
Fu, X.D.4
Tan, E.M.5
-
12
-
-
39149083341
-
Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF65
-
Hastings, M.L., Allemand, E., Duelli, D.M., Myers, M.P. &Krainer, A.R. Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF65. PLoS ONE 2, e538 (2007).
-
(2007)
PLoS ONE
, vol.2
, pp. e538
-
-
Hastings, M.L.1
Allemand, E.2
Duelli, D.M.3
Myers, M.P.4
Krainer, A.R.5
-
13
-
-
0032806445
-
PUF60: A novel U2AF65-related splicing activity
-
Page-McCaw, P.S., Amonlirdviman, K. &Sharp, P.A. PUF60: a novel U2AF65-related splicing activity. RNA 5, 1548-1560 (1999).
-
(1999)
RNA
, vol.5
, pp. 1548-1560
-
-
Page-Mccaw, P.S.1
Amonlirdviman, K.2
Sharp, P.A.3
-
14
-
-
0039769985
-
A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA
-
Tronchre, H., Wang, J. &Fu, X.D. A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA. Nature 388, 397-400 (1997).
-
(1997)
Nature
, vol.388
, pp. 397-400
-
-
Tronchre, H.1
Wang, J.2
Fu, X.D.3
-
15
-
-
0036006512
-
Characterization of U2AF6, a splicing factor related to U2AF35
-
Shepard, J., Reick, M., Olson, S. &Graveley, B.R. Characterization of U2AF6, a splicing factor related to U2AF35. Mol. Cell. Biol. 22, 221-230 (2002).
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 221-230
-
-
Shepard, J.1
Reick, M.2
Olson, S.3
Graveley, B.R.4
-
16
-
-
33750062258
-
Diversity of human U2AF splicing factors
-
Mollet, I., Barbosa-Morais, N.L., Andrade, J. &Carmo-Fonseca, M. Diversity of human U2AF splicing factors. FEBS J. 273, 4807-4816 (2006).
-
(2006)
FEBS J
, vol.273
, pp. 4807-4816
-
-
Mollet, I.1
Barbosa-Morais, N.L.2
Andrade, J.3
Carmo-Fonseca, M.4
-
17
-
-
84873323035
-
Direct competition between hnRNP C and U2AF65 protects the transcriptome from the exonization of Alu elements
-
Zarnack, K. et al. Direct competition between hnRNP C and U2AF65 protects the transcriptome from the exonization of Alu elements. Cell 152, 453-466 (2013).
-
(2013)
Cell
, vol.152
, pp. 453-466
-
-
Zarnack, K.1
-
18
-
-
47249112264
-
Identification of motifs that function in the splicing of non-cannonical introns
-
Murray, J.I., Voelker, R.B., Henscheid, K.L., Warf, M.B. &Berglund, J.A. Identification of motifs that function in the splicing of non-cannonical introns. Genome Biol. 9, R97 (2008).
-
(2008)
Genome Biol
, vol.9
, pp. R97
-
-
Murray, J.I.1
Voelker, R.B.2
Henscheid, K.L.3
Warf, M.B.4
Berglund, J.A.5
-
19
-
-
84866927694
-
YB-1 binds to CAUC motifs and stimulates exon inclusion by enhancing the recruitment of U2AF to weak polypyrimidine tracts
-
Wei, W.J. et al. YB-1 binds to CAUC motifs and stimulates exon inclusion by enhancing the recruitment of U2AF to weak polypyrimidine tracts. Nucleic Acids Res. 40, 8622-8636 (2012).
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 8622-8636
-
-
Wei, W.J.1
-
20
-
-
0024808994
-
The organization of 3 splice-site sequences in mammalian introns
-
Reed, R. The organization of 3' splice-site sequences in mammalian introns. Genes Dev. 3, 2113-2123 (1989).
-
(1989)
Genes Dev
, vol.3
, pp. 2113-2123
-
-
Reed, R.1
-
21
-
-
0026026981
-
Biochemical characterization of U2 snRNP auxiliary factor: An essential pre-mRNA splicing factor with a novel intranuclear distribution
-
Zamore, P.D. &Green, M.R. Biochemical characterization of U2 snRNP auxiliary factor: an essential pre-mRNA splicing factor with a novel intranuclear distribution. EMBO J. 10, 207-214 (1991).
-
(1991)
EMBO J
, vol.10
, pp. 207-214
-
-
Zamore, P.D.1
Green, M.R.2
-
22
-
-
0033576626
-
Functional recognition of the 3' splice site AG by the splicing factor U2AF35
-
Wu, S., Romfo, C.M., Nilsen, T.W. &Green, M.R. Functional recognition of the 3' splice site AG by the splicing factor U2AF35. Nature 402, 832-835 (1999).
-
(1999)
Nature
, vol.402
, pp. 832-835
-
-
Wu, S.1
Romfo, C.M.2
Nilsen, T.W.3
Green, M.R.4
-
23
-
-
0033576625
-
Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG
-
Merendino, L., Guth, S., Bilbao, D., Martinez, C. &Valcarcel, J. Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG. Nature 402, 838-841 (1999).
-
(1999)
Nature
, vol.402
, pp. 838-841
-
-
Merendino, L.1
Guth, S.2
Bilbao, D.3
Martinez, C.4
Valcarcel, J.5
-
24
-
-
33750053338
-
In vivo requirement of the small subunit of U2AF for recognition of a weak 3' splice site
-
Pacheco, T.R., Coelho, M.B., Desterro, J.M., Mollet, I. &Carmo-Fonseca, M. In vivo requirement of the small subunit of U2AF for recognition of a weak 3' splice site. Mol. Cell. Biol. 26, 8183-8190 (2006).
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 8183-8190
-
-
Pacheco, T.R.1
Coelho, M.B.2
Desterro, J.M.3
Mollet, I.4
Carmo-Fonseca, M.5
-
25
-
-
33745608726
-
Intron removal requires proofreading of U2AF/3' splice site recognition by DEK
-
Soares, L.M., Zanier, K., Mackereth, C., Sattler, M. &Valcarcel, J. Intron removal requires proofreading of U2AF/3' splice site recognition by DEK. Science 312, 1961-1965 (2006).
-
(2006)
Science
, vol.312
, pp. 1961-1965
-
-
Soares, L.M.1
Zanier, K.2
Mackereth, C.3
Sattler, M.4
Valcarcel, J.5
-
26
-
-
84856786440
-
Hnrnp A1 proofreads 3' splice site recognition by U2AF
-
Tavanez, J.P., Madl, T., Kooshapur, H., Sattler, M. &Valcarcel, J. hnRNP A1 proofreads 3' splice site recognition by U2AF. Mol. Cell 45, 314-329 (2012).
-
(2012)
Mol. Cell
, vol.45
, pp. 314-329
-
-
Tavanez, J.P.1
Madl, T.2
Kooshapur, H.3
Sattler, M.4
Valcarcel, J.5
-
27
-
-
8644278829
-
Identification of alternative splicing regulators by RNA interference in Drosophila
-
Park, J.W., Parisky, K., Celotto, A.M., Reenan, R.A. &Graveley, B.R. Identification of alternative splicing regulators by RNA interference in Drosophila. Proc. Natl. Acad. Sci. USA 101, 15974-15979 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 15974-15979
-
-
Park, J.W.1
Parisky, K.2
Celotto, A.M.3
Reenan, R.A.4
Graveley, B.R.5
-
28
-
-
77955662560
-
An alternative splicing network links cell-cycle control to apoptosis
-
Moore, M.J., Wang, Q., Kennedy, C.J. &Silver, P.A. An alternative splicing network links cell-cycle control to apoptosis. Cell 142, 625-636 (2010).
-
(2010)
Cell
, vol.142
, pp. 625-636
-
-
Moore, M.J.1
Wang, Q.2
Kennedy, C.J.3
Silver, P.A.4
-
29
-
-
0035798601
-
TIA-1 and TIAR activate splicing of alternative exons with weak 5' splice sites followed by a U-rich stretch on their own pre-mRNAs
-
Le Guiner, C. et al. TIA-1 and TIAR activate splicing of alternative exons with weak 5' splice sites followed by a U-rich stretch on their own pre-mRNAs. J. Biol. Chem. 276, 40638-40646 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 40638-40646
-
-
Le Guiner, C.1
-
30
-
-
78149393552
-
ICLIP predicts the dual splicing effects of TIA-RNA interactions
-
Wang, Z. et al. iCLIP predicts the dual splicing effects of TIA-RNA interactions. PLoS Biol. 8, e1000530 (2010).
-
(2010)
PLoS Biol
, vol.8
, pp. e1000530
-
-
Wang, Z.1
-
31
-
-
72149117411
-
Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping
-
Xue, Y. et al. Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. Mol. Cell 36, 996-1006 (2009).
-
(2009)
Mol. Cell
, vol.36
, pp. 996-1006
-
-
Xue, Y.1
-
32
-
-
79960594889
-
Using positional distribution to identify splicing elements and predict pre-mRNA processing defects in human genes
-
Lim, K.H., Ferraris, L., Filloux, M.E., Raphael, B.J. &Fairbrother, W.G. Using positional distribution to identify splicing elements and predict pre-mRNA processing defects in human genes. Proc. Natl. Acad. Sci. USA 108, 11093-11098 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11093-11098
-
-
Lim, K.H.1
Ferraris, L.2
Filloux, M.E.3
Raphael, B.J.4
Fairbrother, W.G.5
-
33
-
-
80053900941
-
Frequent pathway mutations of splicing machinery in myelodysplasia
-
Yoshida, K. et al. Frequent pathway mutations of splicing machinery in myelodysplasia. Nature 478, 64-69 (2011).
-
(2011)
Nature
, vol.478
, pp. 64-69
-
-
Yoshida, K.1
-
34
-
-
84859856420
-
Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes
-
Thol, F. et al. Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes. Blood 119, 3578-3584 (2012).
-
(2012)
Blood
, vol.119
, pp. 3578-3584
-
-
Thol, F.1
-
35
-
-
84891301466
-
The genetic basis of myelodysplasia and its clinical relevance
-
Cazzola, M., Della Porta, M.G. &Malcovati, L. The genetic basis of myelodysplasia and its clinical relevance. Blood 122, 4021-4034 (2013).
-
(2013)
Blood
, vol.122
, pp. 4021-4034
-
-
Cazzola, M.1
Della Porta, M.G.2
Malcovati, L.3
-
36
-
-
34250012298
-
Splicing factors stimulate polyadenylation via USEs at non-canonical 3' end formation signals
-
Danckwardt, S. et al. Splicing factors stimulate polyadenylation via USEs at non-canonical 3' end formation signals. EMBO J. 26, 2658-2669 (2007).
-
(2007)
EMBO J
, vol.26
, pp. 2658-2669
-
-
Danckwardt, S.1
-
37
-
-
79960230895
-
Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data
-
Zhang, C. &Darnell, R.B. Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data. Nat. Biotechnol. 29, 607-614 (2011).
-
(2011)
Nat. Biotechnol
, vol.29
, pp. 607-614
-
-
Zhang, C.1
Darnell, R.B.2
-
38
-
-
2442441507
-
Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals
-
Yeo, G. &Burge, C.B. Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals. J. Comput. Biol. 11, 377-394 (2004).
-
(2004)
J. Comput. Biol
, vol.11
, pp. 377-394
-
-
Yeo, G.1
Burge, C.B.2
-
39
-
-
2942648436
-
Genome-wide analysis reveals an unexpected function for the Drosophila splicing factor U2AF50 in the nuclear export of intronless mRNAs
-
Blanchette, M., Labourier, E., Green, R.E., Brenner, S.E. &Rio, D.C. Genome-wide analysis reveals an unexpected function for the Drosophila splicing factor U2AF50 in the nuclear export of intronless mRNAs. Mol. Cell 14, 775-786 (2004).
-
(2004)
Mol. Cell
, vol.14
, pp. 775-786
-
-
Blanchette, M.1
Labourier, E.2
Green, R.E.3
Brenner, S.E.4
Rio, D.C.5
-
40
-
-
33847693938
-
Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors
-
Gama-Carvalho, M., Barbosa-Morais, N.L., Brodsky, A.S., Silver, P.A. &Carmo-Fonseca, M. Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors. Genome Biol. 7, R113 (2006).
-
(2006)
Genome Biol
, vol.7
, pp. R113
-
-
Gama-Carvalho, M.1
Barbosa-Morais, N.L.2
Brodsky, A.S.3
Silver, P.A.4
Carmo-Fonseca, M.5
-
41
-
-
84862807502
-
Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturation
-
Xiao, R. et al. Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturation. Mol. Cell 45, 656-668 (2012).
-
(2012)
Mol. Cell
, vol.45
, pp. 656-668
-
-
Xiao, R.1
-
42
-
-
84922255144
-
Context-dependent control of alternative splicing by RNA-binding proteins
-
Fu, X.-D. &Ares, M. Jr. Context-dependent control of alternative splicing by RNA-binding proteins. Nat. Rev. Genet. 15, 689-701 (2014).
-
(2014)
Nat. Rev. Genet
, vol.15
, pp. 689-701
-
-
Fu, X.-D.1
Ares, M.2
-
43
-
-
84864910082
-
The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus
-
Zhou, Z. et al. The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus. Mol. Cell 47, 422-433 (2012).
-
(2012)
Mol. Cell
, vol.47
, pp. 422-433
-
-
Zhou, Z.1
-
44
-
-
84886905271
-
Patterns of missplicing due to somati U2AF1 mutations in myoloid neoplasms
-
Przychodzen, B. et al. Patterns of missplicing due to somati U2AF1 mutations in myoloid neoplasms. Blood 122, 999-1006 (2013).
-
(2013)
Blood
, vol.122
, pp. 999-1006
-
-
Przychodzen, B.1
-
45
-
-
78049446517
-
The U2AF35-related protein Urp contacts the 3' splice site to promote U12-type intron splicing and the second step of U2-type intron splicing
-
Shen, H., Zheng, X., Luecke, S. &Green, M.R. The U2AF35-related protein Urp contacts the 3' splice site to promote U12-type intron splicing and the second step of U2-type intron splicing. Genes Dev. 24, 2389-2394 (2010).
-
(2010)
Genes Dev
, vol.24
, pp. 2389-2394
-
-
Shen, H.1
Zheng, X.2
Luecke, S.3
Green, M.R.4
-
46
-
-
0032483307
-
Extracting regulatory sites from the upstream region of yeast genes by computational analysis of oligonucleotide frequencies
-
van Helden, J., André, B. &Collado-Vides, J. Extracting regulatory sites from the upstream region of yeast genes by computational analysis of oligonucleotide frequencies. J. Mol. Biol. 281, 827-842 (1998).
-
(1998)
J. Mol. Biol
, vol.281
, pp. 827-842
-
-
Van Helden, J.1
André, B.2
Collado-Vides, J.3
|