Low level pro-inflammatory cytokines decrease connexin36 gap junction coupling in mouse and human islets through nitric oxide-mediated protein kinase Cδ

Journal of Biological Chemistry

Volumn 291, Issue 7, 2016, Pages 3184-3196

  Farnsworth, Nikki L ^a,b   Walter, Rachelle L ^b   Hemmati, Alireza ^b   Westacott, Matthew J ^b   Benninger, Richard K P ^a,b  

^a UNIVERSITY OF COLORADO DENVER   (United States)

^b The University of Colorado Denver   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CELL DEATH; DYNAMICS; NITRIC OXIDE;

CALCIUM DYNAMICS; CALCIUM OSCILLATION; CYTOKINE TREATMENT; GAP JUNCTIONS; INSULIN SECRETION; ISOLATED MOUSE; PRO-INFLAMMATORY CYTOKINES; PROTEIN KINASE;

INSULIN;

CALCIUM; CONNEXIN 36; CYTOKINE; GAMMA INTERFERON; GLUCOSE; INSULIN; INTERLEUKIN 1BETA; NITRIC OXIDE; PROTEIN KINASE C DELTA; TUMOR NECROSIS FACTOR ALPHA; ENZYME INHIBITOR; GAP JUNCTION PROTEIN; IL1B PROTEIN, MOUSE; PRKCD PROTEIN, HUMAN; PRKCD PROTEIN, MOUSE; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CELL DAMAGE; CELL DEATH; CELL FUNCTION; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DYNAMICS; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GAP JUNCTION COUPLING; HUMAN; HUMAN CELL; INSULIN RELEASE; MEMBRANE STRUCTURE; MOUSE; NONHUMAN; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GAP JUNCTION; GENETICS; IMMUNOLOGY; IMPAIRED GLUCOSE TOLERANCE; METABOLISM; PANCREAS ISLET; PATHOLOGY; SECRETION (PROCESS); TISSUE BANK; TISSUE CULTURE TECHNIQUE;

ANIMALS; CALCIUM SIGNALING; CELL SURVIVAL; CONNEXINS; CYTOKINES; ENZYME ACTIVATION; ENZYME INHIBITORS; GAP JUNCTIONS; HUMANS; INSULIN; INTERFERON-GAMMA; INTERLEUKIN-1BETA; ISLETS OF LANGERHANS; MICE, INBRED C57BL; NITRIC OXIDE; PREDIABETIC STATE; PROTEIN KINASE C-DELTA; RECOMBINANT PROTEINS; TISSUE BANKS; TISSUE CULTURE TECHNIQUES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84966372705     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.679506     Document Type: Article

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