Retinoid X receptor and its partners in the nuclear receptor family

Current Opinion in Structural Biology

Volumn 11, Issue 1, 2001, Pages 33-38

  Rastinejad, F ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; RETINOID X RECEPTOR;

BASE PAIRING; BINDING SITE; CONFORMATIONAL TRANSITION; DIMERIZATION; DNA BINDING; DNA PROTEIN COMPLEX; DNA RESPONSIVE ELEMENT; DNA STRUCTURE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; REVIEW; SEQUENCE ANALYSIS;

EID: 0035253128     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-440X(00)00165-2     Document Type: Review

References (37)

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12. Structural elements of an orphan nuclear receptor-DNA complex
13. DNA-binding mechanism of the monomeric orphan receptor NGFI-B
14. Millisecond to microsecond time scale dynamics of the retinoid X and retinoic acid receptor DNA-binding domains and dimeric complex formation
15. DNA-induced conformational changes are the basis for cooperative dimerization by the DNA binding domain of the retinoid X receptor
16. Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling
17. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
18. Unique response pathways are established by allosteric interactions among nuclear hormone receptors
19. RXR beta: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements
20. The dimerization interfaces formed between the DNA binding domains of RXR, RAR, and TR determine the binding specificity and polarity of the full-length receptors to direct repeats
21. Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors
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23. Determinants for selective RAR and TR recognition of direct repeat HREs
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26. Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences
27. Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex
28. Structure of a HoxB1-Pbx1 heterodimer bound to DNA: Role of the hexapeptide and a fourth homeodomain helix in complex formation
29. An extradenticle-induced conformational change in a HOX protein ovecomes an inhibitory function of the conserved hexapeptide motif
30. Oct-1 POU domain-DNA interactions: Cooperative binding of isolated subdomains and effects of covalent linkage
31. Transcription factors: The right combination for the DNA lock
32. Identification of deoxyribonucleic acid sequences that bind retinoid-X receptor-gamma with high affinity
33. Sequence requirements for high affinity retinoid X receptor-alpha homodimer binding
34. High-resolution solution structure of the retinoid X receptor DNA-binding domain
35. Allosteric effects of DNA on transcriptional regulators
36. Helix bending as a factor in protein/DNA recognition
37. DNA bending-the prevalence of kinkiness and the virtues of normality