-
1
-
-
39649122136
-
Cancer epigenetics: Modifications, screening, and therapy
-
Gal-Yam, E. N., Saito, Y., Egger, G. & Jones, P. A. Cancer epigenetics: modifications, screening, and therapy. Annu. Rev. Med. 59, 267-280 (2008).
-
(2008)
Annu. Rev. Med.
, vol.59
, pp. 267-280
-
-
Gal-Yam, E.N.1
Saito, Y.2
Egger, G.3
Jones, P.A.4
-
2
-
-
33644856123
-
Epigenetic therapy of cancer: Past, present and future
-
Yoo, C. B. & Jones, P. A. Epigenetic therapy of cancer: past, present and future. Nat. Rev. Drug Discov. 5, 37-50 (2006).
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 37-50
-
-
Yoo, C.B.1
Jones, P.A.2
-
3
-
-
84940403834
-
DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
-
Roulois, D. et al. DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts. Cell 162, 961-973 (2015).
-
(2015)
Cell
, vol.162
, pp. 961-973
-
-
Roulois, D.1
-
4
-
-
84940381273
-
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
-
Chiappinelli, K. B. et al. Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses. Cell 162, 974-986 (2015).
-
(2015)
Cell
, vol.162
, pp. 974-986
-
-
Chiappinelli, K.B.1
-
5
-
-
67349123408
-
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
-
Sato, T. et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459, 262-265 (2009).
-
(2009)
Nature
, vol.459
, pp. 262-265
-
-
Sato, T.1
-
6
-
-
73049116186
-
Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro
-
Barker, N. et al. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 6, 25-36 (2010).
-
(2010)
Cell Stem Cell
, vol.6
, pp. 25-36
-
-
Barker, N.1
-
7
-
-
78751644734
-
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
-
Sato, T. et al. Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Nature 469, 415-418 (2011).
-
(2011)
Nature
, vol.469
, pp. 415-418
-
-
Sato, T.1
-
8
-
-
80054857419
-
Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium
-
Sato, T. et al. Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. Gastroenterology 141, 1762-1772 (2011).
-
(2011)
Gastroenterology
, vol.141
, pp. 1762-1772
-
-
Sato, T.1
-
9
-
-
84873712443
-
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
-
Huch, M. et al. In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration. Nature 494, 247-250 (2013).
-
(2013)
Nature
, vol.494
, pp. 247-250
-
-
Huch, M.1
-
10
-
-
84885846800
-
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis
-
Huch, M. et al. Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis. EMBO J. 32, 2708-2721 (2013).
-
(2013)
EMBO J
, vol.32
, pp. 2708-2721
-
-
Huch, M.1
-
11
-
-
79960990066
-
R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling
-
Carmon, K. S., Gong, X., Lin, Q., Thomas, A. & Liu, Q. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Proc. Natl. Acad. Sci. USA 108, 11452-11457 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11452-11457
-
-
Carmon, K.S.1
Gong, X.2
Lin, Q.3
Thomas, A.4
Liu, Q.5
-
12
-
-
80051926611
-
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
-
de Lau, W. et al. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature 476, 293-297 (2011).
-
(2011)
Nature
, vol.476
, pp. 293-297
-
-
De Lau, W.1
-
13
-
-
84928974420
-
Prospective derivation of a living organoid biobank of colorectal cancer patients
-
van de Wetering, M. et al. Prospective derivation of a living organoid biobank of colorectal cancer patients. Cell 161, 933-945 (2015).
-
(2015)
Cell
, vol.161
, pp. 933-945
-
-
Van De Wetering, M.1
-
14
-
-
84856490464
-
Controlled gene expression in primary Lgr5 organoid cultures
-
Koo, B. K. et al. Controlled gene expression in primary Lgr5 organoid cultures. Nat. Methods 9, 81-83 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 81-83
-
-
Koo, B.K.1
-
15
-
-
33645944979
-
Prion infection influences murine endogenous retrovirus expression in neuronal cells
-
Stengel, A. et al. Prion infection influences murine endogenous retrovirus expression in neuronal cells. Biochem. Biophys. Res. Commun. 343, 825-831 (2006).
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.343
, pp. 825-831
-
-
Stengel, A.1
-
16
-
-
84877105733
-
Toll-like receptor 3 and RIG-I-like receptor activation induces innate antiviral responses in mouse ovarian granulosa cells
-
Yan, K. et al. Toll-like receptor 3 and RIG-I-like receptor activation induces innate antiviral responses in mouse ovarian granulosa cells. Mol. Cell. Endocrinol. 372, 73-85 (2013).
-
(2013)
Mol. Cell. Endocrinol.
, vol.372
, pp. 73-85
-
-
Yan, K.1
-
17
-
-
0029001154
-
Suppression of intestinal neoplasia by DNA hypomethylation
-
Laird, P. W. et al. Suppression of intestinal neoplasia by DNA hypomethylation. Cell 81, 197-205 (1995).
-
(1995)
Cell
, vol.81
, pp. 197-205
-
-
Laird, P.W.1
-
18
-
-
61549106628
-
Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice
-
Yoo, C. B. et al. Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice. Cancer Prev Res 1, 233-240 (2008).
-
(2008)
Cancer Prev Res
, vol.1
, pp. 233-240
-
-
Yoo, C.B.1
|