Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice

Cancer Prevention Research

Volumn 1, Issue 4, 2008, Pages 233-240

  Yoo, Christine B ^a   Chuang, Jody C ^a   Byun, Hyang Min ^a   Egger, Gerda ^b   Yang, Allen S ^a,b   Dubeau, Louis ^a,b   Long, Tiffany ^a,b   Laird, Peter W ^a,b   Marquez, Victor E ^c   Jones, Peter A ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIMETABOLITE; CYTIDINE; DRUG DERIVATIVE; PYRIMIDIN 2 ONE BETA RIBOFURANOSIDE; PYRIMIDIN-2-ONE BETA-RIBOFURANOSIDE;

ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; C57BL MOUSE; CARCINOMA; DNA METHYLATION; DNA MICROARRAY; DRUG EFFECT; EVALUATION; FEMALE; GENE EXPRESSION PROFILING; GENETIC EPIGENESIS; GENETICS; INTESTINE MUCOSA; INTESTINE TUMOR; MALE; METABOLISM; MOUSE; ORAL DRUG ADMINISTRATION; SEXUAL DEVELOPMENT; TIME; TRANSGENIC MOUSE; TUMOR SUPPRESSOR GENE;

ADMINISTRATION, ORAL; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CARCINOMA; CYTIDINE; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION PROFILING; GENES, APC; INTESTINAL MUCOSA; INTESTINAL NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN SPECIFICITY; SEX CHARACTERISTICS; TIME FACTORS;

EID: 61549106628     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-07-0008     Document Type: Article

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