-
1
-
-
84933586864
-
Talimogene laherparepvec improves durable response rate in patients with advanced melanoma
-
Andtbacka RH, Kaufman HL, Collichio F, et al. Talimogene laherparepvec improves durable response rate in patients with advanced melanoma. J Clin Oncol. 2015;33(25):2780–2788.
-
(2015)
J Clin Oncol
, vol.33
, Issue.25
, pp. 2780-2788
-
-
Andtbacka, R.H.1
Kaufman, H.L.2
Collichio, F.3
-
2
-
-
84856689838
-
Oncolytic virus therapy for glioblastoma multiforme: Concepts and candidates
-
Wollmann G, Ozduman K, van den Pol AN. Oncolytic virus therapy for glioblastoma multiforme: concepts and candidates. Cancer J. 2012;18(1):69–81.
-
(2012)
Cancer J
, vol.18
, Issue.1
, pp. 69-81
-
-
Wollmann, G.1
Ozduman, K.2
van den Pol, A.N.3
-
3
-
-
84949488762
-
Evidence for oncolytic virotherapy: Where have we got to and where are we going?
-
Turnbull S, West EJ, Scott KJ, Appleton E, Melcher A, Ralph C. Evidence for oncolytic virotherapy: where have we got to and where are we going? Viruses. 2015;7(12):6291–6312.
-
(2015)
Viruses
, vol.7
, Issue.12
, pp. 6291-6312
-
-
Turnbull, S.1
West, E.J.2
Scott, K.J.3
Appleton, E.4
Melcher, A.5
Ralph, C.6
-
4
-
-
84949682049
-
Retargeting oncolytic vesicular stomatitis virus to human T-cell lymphotropic virus type 1-associated adult T-cell leukemia
-
Betancourt D, Ramos JC, Barber GN. Retargeting oncolytic vesicular stomatitis virus to human T-cell lymphotropic virus type 1-associated adult T-cell leukemia. J Virol. 2015;89:11786–11800.
-
(2015)
J Virol
, vol.89
, pp. 11786-11800
-
-
Betancourt, D.1
Ramos, J.C.2
Barber, G.N.3
-
5
-
-
84871960565
-
Standards of care for treatment of recurrent glioblastoma–are we there yet?
-
Weller M, Cloughesy T, Perry JR, Wick W. Standards of care for treatment of recurrent glioblastoma–are we there yet? Neuro Oncol. 2013;15(1):4–27.
-
(2013)
Neuro Oncol
, vol.15
, Issue.1
, pp. 4-27
-
-
Weller, M.1
Cloughesy, T.2
Perry, J.R.3
Wick, W.4
-
6
-
-
84896125494
-
Evolution of the cancer stem cell model
-
Kreso A, Dick JE. Evolution of the cancer stem cell model. Cell Stem Cell. 2014;14:275–291.
-
(2014)
Cell Stem Cell
, vol.14
, pp. 275-291
-
-
Kreso, A.1
Dick, J.E.2
-
7
-
-
84902269863
-
Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy
-
Auffinger B, Tobias AL, Han Y, et al. Conversion of differentiated cancer cells into cancer stem-like cells in a glioblastoma model after primary chemotherapy. Cell Death Differ. 2014;21:1119–1131.
-
(2014)
Cell Death Differ
, vol.21
, pp. 1119-1131
-
-
Auffinger, B.1
Tobias, A.L.2
Han, Y.3
-
8
-
-
84865176530
-
Ionizing radiation induces stemness in cancer cells
-
Ghisolfi L, Keates AC, Hu X, Lee DK, Li CJ. Ionizing radiation induces stemness in cancer cells. PLoS One. 2012;7(8):ea43628.
-
(2012)
Plos One
, vol.7
, Issue.8
-
-
Ghisolfi, L.1
Keates, A.C.2
Hu, X.3
Lee, D.K.4
Li, C.J.5
-
9
-
-
84958057302
-
Cancer stem cells and tumor-associated macrophages: A roadmap for multitargeting strategies
-
Raggi C, Mousa HS, Correnti M, Sica A, Invernizzi P. Cancer stem cells and tumor-associated macrophages: a roadmap for multitargeting strategies. Oncogene. 2016;35(6):671–682.
-
(2016)
Oncogene
, vol.35
, Issue.6
, pp. 671-682
-
-
Raggi, C.1
Mousa, H.S.2
Correnti, M.3
Sica, A.4
Invernizzi, P.5
-
10
-
-
67349247048
-
Oncolytic reovirus effectively targets breast cancer stem cells
-
Marcato P, Dean CA, Giacomantonio CA, Lee PW. Oncolytic reovirus effectively targets breast cancer stem cells. Mol Ther. 2009;17(6):972–979.
-
(2009)
Mol Ther
, vol.17
, Issue.6
, pp. 972-979
-
-
Marcato, P.1
Dean, C.A.2
Giacomantonio, C.A.3
Lee, P.W.4
-
11
-
-
84884186952
-
YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells
-
Mantwill K, Naumann U, Seznec J, et al. YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells. J Transl Med. 2013;11:216.
-
(2013)
J Transl Med
, vol.11
, pp. 216
-
-
Mantwill, K.1
Naumann, U.2
Seznec, J.3
-
12
-
-
84897570280
-
Calpain-dependent clearance of the autophagy protein p62/SQSTM1 is a contributor to DeltaPK oncolytic activity in melanoma
-
Colunga A, Bollino D, Schech A, Aurelian L. Calpain-dependent clearance of the autophagy protein p62/SQSTM1 is a contributor to DeltaPK oncolytic activity in melanoma. Gene Ther. 2014;21(4):371–378.
-
(2014)
Gene Ther
, vol.21
, Issue.4
, pp. 371-378
-
-
Colunga, A.1
Bollino, D.2
Schech, A.3
Aurelian, L.4
-
13
-
-
84920488305
-
Oncolytic viral therapy: Targeting cancer stem cells
-
Smith TT, Roth JC, Friedman GK, Gillespie GY. Oncolytic viral therapy: targeting cancer stem cells. Oncolytic Virother. 2014;2014(3):21–33.
-
(2014)
Oncolytic Virother
, vol.2014
, Issue.3
, pp. 21-33
-
-
Smith, T.T.1
Roth, J.C.2
Friedman, G.K.3
Gillespie, G.Y.4
-
14
-
-
66449122303
-
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells
-
Bellodi C, Lidonnici MR, Hamilton A, et al. Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J Clin Invest. 2009;119:1109–1123.
-
(2009)
J Clin Invest
, vol.119
, pp. 1109-1123
-
-
Bellodi, C.1
Lidonnici, M.R.2
Hamilton, A.3
-
15
-
-
34748880650
-
Examination of the therapeutic potential of delta-24-RGD in brain tumor stem cells: Role of autophagic cell death
-
Jiang H, Gomez-Manzano C, Aoki H, et al. Examination of the therapeutic potential of delta-24-RGD in brain tumor stem cells: role of autophagic cell death. J Natl Cancer Inst. 2007;99:1410–1414.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1410-1414
-
-
Jiang, H.1
Gomez-Manzano, C.2
Aoki, H.3
-
17
-
-
84900036041
-
Curcumin promotes autophagic survival of a subset of colon cancer stem cells, which are ablated by DCLK1-siRNA
-
Kantara C, O’Connell M, Sarkar S, Moya S, Ullrich R, Singh P. Curcumin promotes autophagic survival of a subset of colon cancer stem cells, which are ablated by DCLK1-siRNA. Cancer Res. 2014;74:2487–2498.
-
(2014)
Cancer Res
, vol.74
, pp. 2487-2498
-
-
Kantara, C.1
O’Connell, M.2
Sarkar, S.3
Moya, S.4
Ullrich, R.5
Singh, P.6
-
18
-
-
84877584521
-
Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells
-
Gong C, Bauvy C, Tonelli G, et al. Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells. Oncogene. 2013;32:2261–2272.
-
(2013)
Oncogene
, vol.32
, pp. 2261-2272
-
-
Gong, C.1
Bauvy, C.2
Tonelli, G.3
-
19
-
-
84889012246
-
Role of the hypoxia-inducible factor-1 alpha induced autophagy in the conversion of non-stem pancreatic cancer cells into CD133+ pancreatic cancer stem-like cells
-
Zhu H, Wang D, Liu Y, et al. Role of the hypoxia-inducible factor-1 alpha induced autophagy in the conversion of non-stem pancreatic cancer cells into CD133+ pancreatic cancer stem-like cells. Cancer Cell Int. 2013;13:119.
-
(2013)
Cancer Cell Int
, vol.13
, pp. 119
-
-
Zhu, H.1
Wang, D.2
Liu, Y.3
-
20
-
-
84908389410
-
Autophagy inhibition suppresses the tumorigenic potential of cancer stem cell enriched side population in bladder cancer
-
Ojha R, Jha V, Singh SK, Bhattacharyya S. Autophagy inhibition suppresses the tumorigenic potential of cancer stem cell enriched side population in bladder cancer. Biochim Biophys Acta. 2014;1842:2073–2086.
-
(2014)
Biochim Biophys Acta
, vol.1842
, pp. 2073-2086
-
-
Ojha, R.1
Jha, V.2
Singh, S.K.3
Bhattacharyya, S.4
-
21
-
-
84877918290
-
Targeting autophagy to enhance oncolytic virus-based cancer therapy
-
Meng S, Xu J, Wu Y, Ding C. Targeting autophagy to enhance oncolytic virus-based cancer therapy. Expert Opin Biol Ther. 2013;13(6):863–873.
-
(2013)
Expert Opin Biol Ther
, vol.13
, Issue.6
, pp. 863-873
-
-
Meng, S.1
Xu, J.2
Wu, Y.3
Ding, C.4
-
22
-
-
67549117101
-
Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells
-
Uhl M, Kepp O, Jusforgues-Saklani H, Vicencio JM, Kroemer G, Albert ML. Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells. Cell Death Differ. 2009;16(7):991–1005.
-
(2009)
Cell Death Differ
, vol.16
, Issue.7
, pp. 991-1005
-
-
Uhl, M.1
Kepp, O.2
Jusforgues-Saklani, H.3
Vicencio, J.M.4
Kroemer, G.5
Albert, M.L.6
-
23
-
-
84925534889
-
Autophagy modulation: A target for cancer treatment development
-
Duffy A, Le J, Sausville E, Emadi A. Autophagy modulation: a target for cancer treatment development. Cancer Chemother Pharmacol. 2015;75(3):439–447.
-
(2015)
Cancer Chemother Pharmacol
, vol.75
, Issue.3
, pp. 439-447
-
-
Duffy, A.1
Le, J.2
Sausville, E.3
Emadi, A.4
-
24
-
-
84904641826
-
Oncolytic viruses as anticancer vaccines
-
Woller N, Gurlevik E, Ureche CI, Schumacher A, Kuhnel F. Oncolytic viruses as anticancer vaccines. Front Oncol. 2014;4:188.
-
(2014)
Front Oncol
, vol.4
, pp. 188
-
-
Woller, N.1
Gurlevik, E.2
Ureche, C.I.3
Schumacher, A.4
Kuhnel, F.5
-
25
-
-
84875601707
-
Activation of the human immune system via toll-like receptors by the oncolytic parvovirus H-1
-
Sieben M, Schafer P, Dinsart C, Galle PR, Moehler M. Activation of the human immune system via toll-like receptors by the oncolytic parvovirus H-1. Int J Cancer. 2013;132(11):2548–2556.
-
(2013)
Int J Cancer
, vol.132
, Issue.11
, pp. 2548-2556
-
-
Sieben, M.1
Schafer, P.2
Dinsart, C.3
Galle, P.R.4
Moehler, M.5
-
26
-
-
58149359320
-
Tumor infection by oncolytic reovirus primes adaptive antitumor immunity
-
Prestwich RJ, Errington F, Ilett EJ, et al. Tumor infection by oncolytic reovirus primes adaptive antitumor immunity. Clin Cancer Res. 2008;14(22):7358–7366.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.22
, pp. 7358-7366
-
-
Prestwich, R.J.1
Errington, F.2
Ilett, E.J.3
-
27
-
-
84861112821
-
Coxsackievirus B3 is an oncolytic virus with immunostimulatory properties that is active against lung adenocarcinoma
-
Miyamoto S, Inoue H, Nakamura T, et al. Coxsackievirus B3 is an oncolytic virus with immunostimulatory properties that is active against lung adenocarcinoma. Cancer Res. 2012;72(10):2609–2621.
-
(2012)
Cancer Res
, vol.72
, Issue.10
, pp. 2609-2621
-
-
Miyamoto, S.1
Inoue, H.2
Nakamura, T.3
-
28
-
-
84873413878
-
The efficacy versus toxicity profile of combination virotherapy and TLR immunotherapy highlights the danger of administering TLR agonists to oncolytic virus-treated mice
-
Rommelfanger DM, Compte M, Diaz RM, et al. The efficacy versus toxicity profile of combination virotherapy and TLR immunotherapy highlights the danger of administering TLR agonists to oncolytic virus-treated mice. Mol Ther. 2013;21(2):348–357.
-
(2013)
Mol Ther
, vol.21
, Issue.2
, pp. 348-357
-
-
Rommelfanger, D.M.1
Compte, M.2
Diaz, R.M.3
-
29
-
-
84874309252
-
Oncolytic vaccinia virus disrupts tumor-associated vasculature in humans
-
Breitbach CJ, Arulanandam R, De Silva N, et al. Oncolytic vaccinia virus disrupts tumor-associated vasculature in humans. Cancer Res. 2013;73(4):1265–1275.
-
(2013)
Cancer Res
, vol.73
, Issue.4
, pp. 1265-1275
-
-
Breitbach, C.J.1
Arulanandam, R.2
De Silva, N.3
-
30
-
-
84904644314
-
Oncolytic viruses and their application to cancer immunotherapy
-
Chiocca EA, Rabkin SD. Oncolytic viruses and their application to cancer immunotherapy. Cancer Immunol Res. 2014;2(4):295–300.
-
(2014)
Cancer Immunol Res
, vol.2
, Issue.4
, pp. 295-300
-
-
Chiocca, E.A.1
Rabkin, S.D.2
-
31
-
-
84957850936
-
Chronic activation of innate immunity correlates with poor prognosis in cancer patients treated with oncolytic adenovirus
-
Taipale K, Liikanen I, Juhila J, et al. Chronic activation of innate immunity correlates with poor prognosis in cancer patients treated with oncolytic adenovirus. Mol Ther. 2016;(1):175–183.
-
(2016)
Mol Ther
, Issue.1
, pp. 175-183
-
-
Taipale, K.1
Liikanen, I.2
Juhila, J.3
-
32
-
-
84918574716
-
Newcastle disease virotherapy induces long-term survival and tumor-specific immune memory in orthotopic glioma through the induction of immunogenic cell death
-
Koks CA, Garg AD, Ehrhardt M, et al. Newcastle disease virotherapy induces long-term survival and tumor-specific immune memory in orthotopic glioma through the induction of immunogenic cell death. Int J Cancer. 2015;136(5):E313–E325.
-
(2015)
Int J Cancer
, vol.136
, Issue.5
, pp. E313-E325
-
-
Koks, C.A.1
Garg, A.D.2
Ehrhardt, M.3
-
33
-
-
84869089109
-
An oncolytic adenovirus enhanced for toll-like receptor 9 stimulation increases antitumor immune responses and tumor clearance
-
Cerullo V, Diaconu I, Romano V, et al. An oncolytic adenovirus enhanced for toll-like receptor 9 stimulation increases antitumor immune responses and tumor clearance. Mol Ther. 2012;20(11):2076–2086.
-
(2012)
Mol Ther
, vol.20
, Issue.11
, pp. 2076-2086
-
-
Cerullo, V.1
Diaconu, I.2
Romano, V.3
-
34
-
-
84863717012
-
Activation of a glioma-specific immune response by oncolytic parvovirus minute virus of mice infection
-
Grekova SP, Raykov Z, Zawatzky R, Rommelaere J, Koch U. Activation of a glioma-specific immune response by oncolytic parvovirus minute virus of mice infection. Cancer Gene Ther. 2012;19(7):468–475.
-
(2012)
Cancer Gene Ther
, vol.19
, Issue.7
, pp. 468-475
-
-
Grekova, S.P.1
Raykov, Z.2
Zawatzky, R.3
Rommelaere, J.4
Koch, U.5
-
35
-
-
80052507771
-
Activating systemic T-cell immunity against self tumor antigens to support oncolytic virotherapy with vesicular stomatitis virus
-
Wongthida P, Diaz RM, Pulido C, et al. Activating systemic T-cell immunity against self tumor antigens to support oncolytic virotherapy with vesicular stomatitis virus. Hum Gene Ther. 2011;22(11):1343–1353.
-
(2011)
Hum Gene Ther
, vol.22
, Issue.11
, pp. 1343-1353
-
-
Wongthida, P.1
Diaz, R.M.2
Pulido, C.3
-
36
-
-
77950518121
-
Enhancing the therapeutic effect against ovarian cancer through a combination of viral oncolysis and antigen-specific immunotherapy
-
Zhang YQ, Tsai YC, Monie A, Wu TC, Hung CF. Enhancing the therapeutic effect against ovarian cancer through a combination of viral oncolysis and antigen-specific immunotherapy. Mol Ther. 2010;18(4):692–699.
-
(2010)
Mol Ther
, vol.18
, Issue.4
, pp. 692-699
-
-
Zhang, Y.Q.1
Tsai, Y.C.2
Monie, A.3
Wu, T.C.4
Hung, C.F.5
-
37
-
-
70349864985
-
Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus
-
Bridle BW, Boudreau JE, Lichty BD, et al. Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus. Mol Ther. 2009;17(10):1814–1821.
-
(2009)
Mol Ther
, vol.17
, Issue.10
, pp. 1814-1821
-
-
Bridle, B.W.1
Boudreau, J.E.2
Lichty, B.D.3
-
38
-
-
84902145394
-
The strength of the T cell response against a surrogate tumor antigen induced by oncolytic VSV therapy does not correlate with tumor control
-
Janelle V, Langlois MP, Lapierre P, Charpentier T, Poliquin L, Lamarre A. The strength of the T cell response against a surrogate tumor antigen induced by oncolytic VSV therapy does not correlate with tumor control. Mol Ther. 2014;22(6):1198–1210.
-
(2014)
Mol Ther
, vol.22
, Issue.6
, pp. 1198-1210
-
-
Janelle, V.1
Langlois, M.P.2
Lapierre, P.3
Charpentier, T.4
Poliquin, L.5
Lamarre, A.6
-
39
-
-
84870239310
-
Immunogenic cell death and DAMPs in cancer therapy
-
Krysko DV, Garg AD, Kaczmarek A, Krysko O, Agostinis P, Vandenabeele P. Immunogenic cell death and DAMPs in cancer therapy. Nat Rev Cancer. 2012;12(12):860–875.
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.12
, pp. 860-875
-
-
Krysko, D.V.1
Garg, A.D.2
Kaczmarek, A.3
Krysko, O.4
Agostinis, P.5
Vandenabeele, P.6
-
41
-
-
76249128304
-
Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity
-
Aymeric L, Apetoh L, Ghiringhelli F, et al. Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity. Cancer Res. 2010;70(3):855–858.
-
(2010)
Cancer Res
, vol.70
, Issue.3
, pp. 855-858
-
-
Aymeric, L.1
Apetoh, L.2
Ghiringhelli, F.3
-
42
-
-
79251628505
-
Stepwise release of biologically active HMGB1 during HSV-2 infection
-
Borde C, Barnay-Verdier S, Gaillard C, Hocini H, Marechal V, Gozlan J. Stepwise release of biologically active HMGB1 during HSV-2 infection. PLoS One. 2011;6(1):e16145.
-
(2011)
Plos One
, vol.6
, Issue.1
-
-
Borde, C.1
Barnay-Verdier, S.2
Gaillard, C.3
Hocini, H.4
Marechal, V.5
Gozlan, J.6
-
43
-
-
84860520650
-
Immune response is an important aspect of the antitumor effect produced by a CD40L-encoding oncolytic adenovirus
-
Diaconu I, Cerullo V, Hirvinen ML, et al. Immune response is an important aspect of the antitumor effect produced by a CD40L-encoding oncolytic adenovirus. Cancer Res. 2012;72(9):2327–2338.
-
(2012)
Cancer Res
, vol.72
, Issue.9
, pp. 2327-2338
-
-
Diaconu, I.1
Cerullo, V.2
Hirvinen, M.L.3
-
44
-
-
84871985834
-
Measles virus causes immunogenic cell death in human melanoma
-
Donnelly OG, Errington-Mais F, Steele L, et al. Measles virus causes immunogenic cell death in human melanoma. Gene Ther. 2013;20(1):7–15.
-
(2013)
Gene Ther
, vol.20
, Issue.1
, pp. 7-15
-
-
Donnelly, O.G.1
Errington-Mais, F.2
Steele, L.3
-
45
-
-
84883642231
-
Oncolytic viruses as therapeutic cancer vaccines
-
Bartlett DL, Liu Z, Sathaiah M, et al. Oncolytic viruses as therapeutic cancer vaccines. Mol Cancer. 2013;12(1):103.
-
(2013)
Mol Cancer
, vol.12
, Issue.1
, pp. 103
-
-
Bartlett, D.L.1
Liu, Z.2
Sathaiah, M.3
-
46
-
-
84923695620
-
Immune suppression during oncolytic virotherapy for high-grade glioma; yes or no?
-
Koks CA, De Vleeschouwer S, Graf N, Van Gool SW. Immune suppression during oncolytic virotherapy for high-grade glioma; yes or no? J Cancer. 2015;6(3):203–217.
-
(2015)
J Cancer
, vol.6
, Issue.3
, pp. 203-217
-
-
Koks, C.A.1
De Vleeschouwer, S.2
Graf, N.3
Van Gool, S.W.4
-
47
-
-
78649926094
-
Definition of an enhanced immune cell therapy in mice that can target stem-like lymphoma cells
-
Contag CH, Sikorski R, Negrin RS, et al. Definition of an enhanced immune cell therapy in mice that can target stem-like lymphoma cells. Cancer Res. 2010;70(23):9837–9845.
-
(2010)
Cancer Res
, vol.70
, Issue.23
, pp. 9837-9845
-
-
Contag, C.H.1
Sikorski, R.2
Negrin, R.S.3
-
48
-
-
78049463446
-
Selectivity of oncolytic viral replication prevents antiviral immune response and toxicity, but does not improve antitumoral immunity
-
Gurlevik E, Woller N, Struver N, et al. Selectivity of oncolytic viral replication prevents antiviral immune response and toxicity, but does not improve antitumoral immunity. Mol Ther. 2010;18(11):1972–1982.
-
(2010)
Mol Ther
, vol.18
, Issue.11
, pp. 1972-1982
-
-
Gurlevik, E.1
Woller, N.2
Struver, N.3
-
49
-
-
84908054077
-
HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells
-
Parker KH, Sinha P, Horn LA, et al. HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells. Cancer Res. 2014;74(20):5723–5733.
-
(2014)
Cancer Res
, vol.74
, Issue.20
, pp. 5723-5733
-
-
Parker, K.H.1
Sinha, P.2
Horn, L.A.3
-
50
-
-
84938513665
-
Serum HMGB1 is a predictive and prognostic biomarker for oncolytic immunotherapy
-
Liikanen I, Koski A, Merisalo-Soikkeli M, et al. Serum HMGB1 is a predictive and prognostic biomarker for oncolytic immunotherapy. Oncoimmunology. 2015;4(3):e989771.
-
(2015)
Oncoimmunology
, vol.4
, Issue.3
-
-
Liikanen, I.1
Koski, A.2
Merisalo-Soikkeli, M.3
-
51
-
-
84959160486
-
ΔPK oncolytic activity includes modulation of tumor cell milieu
-
Bollino D, Colunga A, Li B, Aurelian L. ΔPK oncolytic activity includes modulation of tumor cell milieu. J Gen Virol. 2016;97(2):496–508.
-
(2016)
J Gen Virol
, vol.97
, Issue.2
, pp. 496-508
-
-
Bollino, D.1
Colunga, A.2
Li, B.3
Aurelian, L.4
-
52
-
-
84901044424
-
Oncolytic immunotherapy: Dying the right way is a key to eliciting potent antitumor immunity
-
Guo ZS, Liu Z, Bartlett DL. Oncolytic immunotherapy: dying the right way is a key to eliciting potent antitumor immunity. Front Oncol. 2014;4:74.
-
(2014)
Front Oncol
, vol.4
, pp. 74
-
-
Guo, Z.S.1
Liu, Z.2
Bartlett, D.L.3
-
53
-
-
73349133717
-
Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma
-
Senzer NN, Kaufman HL, Amatruda T, et al. Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma. J Clin Oncol. 2009;27(34):5763–5771.
-
(2009)
J Clin Oncol
, vol.27
, Issue.34
, pp. 5763-5771
-
-
Senzer, N.N.1
Kaufman, H.L.2
Amatruda, T.3
-
54
-
-
77149141965
-
Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma
-
Kaufman HL, Kim DW, DeRaffele G, Mitcham J, Coffin RS, Kim-Schulze S. Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma. Ann Surg Oncol. 2010;17(3):718–730.
-
(2010)
Ann Surg Oncol
, vol.17
, Issue.3
, pp. 718-730
-
-
Kaufman, H.L.1
Kim, D.W.2
Deraffele, G.3
Mitcham, J.4
Coffin, R.S.5
Kim-Schulze, S.6
-
55
-
-
84875225339
-
Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer
-
Heo J, Reid T, Ruo L, et al. Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer. Nat Med. 2013;19(3):329–336.
-
(2013)
Nat Med
, vol.19
, Issue.3
, pp. 329-336
-
-
Heo, J.1
Reid, T.2
Ruo, L.3
-
56
-
-
84878279239
-
Oncolytic and immunotherapeutic vaccinia induces antibody-mediated complement-dependent cancer cell lysis in humans
-
185ra163
-
Kim MK, Breitbach CJ, Moon A, et al. Oncolytic and immunotherapeutic vaccinia induces antibody-mediated complement-dependent cancer cell lysis in humans. Sci Transl Med. 2013;5(185):185ra163.
-
(2013)
Sci Transl Med
, vol.5
, Issue.185
-
-
Kim, M.K.1
Breitbach, C.J.2
Moon, A.3
-
57
-
-
77953160443
-
Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients
-
Cerullo V, Pesonen S, Diaconu I, et al. Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients. Cancer Res. 2010;70(11):4297–4309.
-
(2010)
Cancer Res
, vol.70
, Issue.11
, pp. 4297-4309
-
-
Cerullo, V.1
Pesonen, S.2
Diaconu, I.3
-
58
-
-
77957571590
-
Treatment of cancer patients with a serotype 5/3 chimeric oncolytic adenovirus expressing GMCSF
-
Koski A, Kangasniemi L, Escutenaire S, et al. Treatment of cancer patients with a serotype 5/3 chimeric oncolytic adenovirus expressing GMCSF. Mol Ther. 2010;18(10):1874–1884.
-
(2010)
Mol Ther
, vol.18
, Issue.10
, pp. 1874-1884
-
-
Koski, A.1
Kangasniemi, L.2
Escutenaire, S.3
-
59
-
-
84887229566
-
Evolution of oncolytic viruses: Novel strategies for cancer treatment
-
Atherton MJ, Lichty BD. Evolution of oncolytic viruses: novel strategies for cancer treatment. Immunotherapy. 2013;5(11):1191–1206.
-
(2013)
Immunotherapy
, vol.5
, Issue.11
, pp. 1191-1206
-
-
Atherton, M.J.1
Lichty, B.D.2
-
60
-
-
84875830856
-
Targeting CXCL12/CXCR4 signaling with oncolytic virotherapy disrupts tumor vasculature and inhibits breast cancer metastases
-
Gil M, Seshadri M, Komorowski MP, Abrams SI, Kozbor D. Targeting CXCL12/CXCR4 signaling with oncolytic virotherapy disrupts tumor vasculature and inhibits breast cancer metastases. Proc Natl Acad Sci U S A. 2013;110(14):E1291–E1300.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.14
, pp. E1291-E1300
-
-
Gil, M.1
Seshadri, M.2
Komorowski, M.P.3
Abrams, S.I.4
Kozbor, D.5
-
61
-
-
84910148214
-
CXCL12/CXCR4 blockade by oncolytic virotherapy inhibits ovarian cancer growth by decreasing immunosuppression and targeting cancer-initiating cells
-
Gil M, Komorowski MP, Seshadri M, et al. CXCL12/CXCR4 blockade by oncolytic virotherapy inhibits ovarian cancer growth by decreasing immunosuppression and targeting cancer-initiating cells. J Immunol. 2014;193(10):5327–5337.
-
(2014)
J Immunol
, vol.193
, Issue.10
, pp. 5327-5337
-
-
Gil, M.1
Komorowski, M.P.2
Seshadri, M.3
-
62
-
-
84932168247
-
Dual role of GM-CSF as a pro-inflammatory and a regulatory cytokine: Implications for immune therapy
-
Bhattacharya P, Budnick I, Singh M, et al. Dual role of GM-CSF as a pro-inflammatory and a regulatory cytokine: implications for immune therapy. J Interferon Cytokine Res. 2015;35(8):585–599.
-
(2015)
J Interferon Cytokine Res
, vol.35
, Issue.8
, pp. 585-599
-
-
Bhattacharya, P.1
Budnick, I.2
Singh, M.3
-
63
-
-
77950933188
-
Interference of CD40L-mediated tumor immunotherapy by oncolytic vesicular stomatitis virus
-
Galivo F, Diaz RM, Thanarajasingam U, et al. Interference of CD40L-mediated tumor immunotherapy by oncolytic vesicular stomatitis virus. Hum Gene Ther. 2010;21(4):439–450.
-
(2010)
Hum Gene Ther
, vol.21
, Issue.4
, pp. 439-450
-
-
Galivo, F.1
Diaz, R.M.2
Thanarajasingam, U.3
-
64
-
-
84885757630
-
Immune modulation of the tumor microenvironment for enhancing cancer immunotherapy
-
Devaud C, John LB, Westwood JA, Darcy PK, Kershaw MH. Immune modulation of the tumor microenvironment for enhancing cancer immunotherapy. Oncoimmunology. 2013;2(8):e25961.
-
(2013)
Oncoimmunology
, vol.2
, Issue.8
-
-
Devaud, C.1
John, L.B.2
Westwood, J.A.3
Darcy, P.K.4
Kershaw, M.H.5
-
65
-
-
0036155925
-
Tumor-induced death of immune cells: Its mechanisms and consequences
-
Whiteside TL. Tumor-induced death of immune cells: its mechanisms and consequences. Semin Cancer Biol. 2002;12(1):43–50.
-
(2002)
Semin Cancer Biol
, vol.12
, Issue.1
, pp. 43-50
-
-
Whiteside, T.L.1
-
66
-
-
79952817937
-
Interleukin 10 decreases MICA expression on melanoma cell surface
-
Serrano AE, Menares-Castillo E, Garrido-Tapia M, et al. Interleukin 10 decreases MICA expression on melanoma cell surface. Immunol Cell Biol. 2011;89(3):447–457.
-
(2011)
Immunol Cell Biol
, vol.89
, Issue.3
, pp. 447-457
-
-
Serrano, A.E.1
Menares-Castillo, E.2
Garrido-Tapia, M.3
-
67
-
-
55249095393
-
Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha
-
Ben-Shoshan J, Maysel-Auslender S, Mor A, Keren G, George J. Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha. Eur J Immunol. 2008;38(9):2412–2418.
-
(2008)
Eur J Immunol
, vol.38
, Issue.9
, pp. 2412-2418
-
-
Ben-Shoshan, J.1
Maysel-Auslender, S.2
Mor, A.3
Keren, G.4
George, J.5
-
68
-
-
84899753178
-
PD-L1 is a novel direct target of HIF-1alpha, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
-
Noman MZ, Desantis G, Janji B, et al. PD-L1 is a novel direct target of HIF-1alpha, and its blockade under hypoxia enhanced MDSC-mediated T cell activation. J Exp Med. 2014;211(5):781–790.
-
(2014)
J Exp Med
, vol.211
, Issue.5
, pp. 781-790
-
-
Noman, M.Z.1
Desantis, G.2
Janji, B.3
-
69
-
-
84941695057
-
Myeloid-derived suppressor cells in the tumor microenvironment: Expect the unexpected
-
Marvel D, Gabrilovich DI. Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected. J Clin Invest. 2015;125(9):3356–3364.
-
(2015)
J Clin Invest
, vol.125
, Issue.9
, pp. 3356-3364
-
-
Marvel, D.1
Gabrilovich, D.I.2
-
70
-
-
16844379997
-
Immunosuppressive networks in the tumour environment and their therapeutic relevance
-
Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer. 2005;5(4):263–274.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.4
, pp. 263-274
-
-
Zou, W.1
-
71
-
-
84906779440
-
Cell carriers for oncolytic viruses: Current challenges and future directions
-
Roy DG, Bell JC. Cell carriers for oncolytic viruses: current challenges and future directions. Oncolytic Virother. 2013;2:47–56.
-
(2013)
Oncolytic Virother
, vol.2
, pp. 47-56
-
-
Roy, D.G.1
Bell, J.C.2
-
72
-
-
60449099546
-
Neural stem cells target intracranial glioma to deliver an oncolytic adenovirus in vivo
-
Tyler MA, Ulasov IV, Sonabend AM, et al. Neural stem cells target intracranial glioma to deliver an oncolytic adenovirus in vivo. Gene Ther. 2009;16(2):262–278.
-
(2009)
Gene Ther
, vol.16
, Issue.2
, pp. 262-278
-
-
Tyler, M.A.1
Ulasov, I.V.2
Sonabend, A.M.3
-
73
-
-
57749201655
-
Targeted and armed oncolytic poxviruses: A novel multi-mechanistic therapeutic class for cancer
-
Kirn DH, Thorne SH. Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer. Nat Rev Cancer. 2009;9:64–71.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 64-71
-
-
Kirn, D.H.1
Thorne, S.H.2
-
74
-
-
84890551004
-
Lymphokine-activated killer and dendritic cell carriage enhances oncolytic reovirus therapy for ovarian cancer by overcoming antibody neutralization in ascites
-
Jennings VA, Ilett EJ, Scott KJ, et al. Lymphokine-activated killer and dendritic cell carriage enhances oncolytic reovirus therapy for ovarian cancer by overcoming antibody neutralization in ascites. Int J Cancer. 2014;134:1091–1101.
-
(2014)
Int J Cancer
, vol.134
, pp. 1091-1101
-
-
Jennings, V.A.1
Ilett, E.J.2
Scott, K.J.3
-
75
-
-
77955556150
-
Demonstration of anti-tumor activity of oncolytic measles virus strains in a malignant pleural effusion breast cancer model
-
Iankov I, Msaouel P, Allen C, et al. Demonstration of anti-tumor activity of oncolytic measles virus strains in a malignant pleural effusion breast cancer model. Breast Cancer Res Treat. 2010;122:745–754.
-
(2010)
Breast Cancer Res Treat
, vol.122
, pp. 745-754
-
-
Iankov, I.1
Msaouel, P.2
Allen, C.3
-
76
-
-
67349239329
-
Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity
-
Ilett EJ, Prestwich RJ, Kottke T, et al. Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity. Gene Ther. 2009;16:689–699.
-
(2009)
Gene Ther
, vol.16
, pp. 689-699
-
-
Ilett, E.J.1
Prestwich, R.J.2
Kottke, T.3
-
77
-
-
81255164999
-
Vesicular stomatitis virus oncolytic treatment interferes with tumor-associated dendritic cell functions and abrogates tumor antigen presentation
-
Leveille S, Goulet ML, Lichty BD, Hiscott J. Vesicular stomatitis virus oncolytic treatment interferes with tumor-associated dendritic cell functions and abrogates tumor antigen presentation. J Virol. 2011;85:12160–12169.
-
(2011)
J Virol
, vol.85
, pp. 12160-12169
-
-
Leveille, S.1
Goulet, M.L.2
Lichty, B.D.3
Hiscott, J.4
-
78
-
-
84885953332
-
Systemically delvirus-infected mesenchymal stem cells can evade host immunity to inhibit liver cancer growth
-
Ong HT, Federspiel MJ, Guo CM, et al. Systemically delvirus-infected mesenchymal stem cells can evade host immunity to inhibit liver cancer growth. J Hepatol. 2013;59(5):999–1006.
-
(2013)
J Hepatol
, vol.59
, Issue.5
, pp. 999-1006
-
-
Ong, H.T.1
Federspiel, M.J.2
Guo, C.M.3
-
79
-
-
84878621268
-
HDAC inhibition suppresses primary immune responses, enhances secondary immune responses, and abrogates autoimmunity during tumor immunotherapy
-
Bridle BW, Chen L, Lemay CG, et al. HDAC inhibition suppresses primary immune responses, enhances secondary immune responses, and abrogates autoimmunity during tumor immunotherapy. Mol Ther. 2013;21(4):887–894.
-
(2013)
Mol Ther
, vol.21
, Issue.4
, pp. 887-894
-
-
Bridle, B.W.1
Chen, L.2
Lemay, C.G.3
-
80
-
-
84870909657
-
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors
-
Alvarez-Breckenridge CA, Yu J, Price R, et al. NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors. Nat Med. 2012;18(12):1827–1834.
-
(2012)
Nat Med
, vol.18
, Issue.12
, pp. 1827-1834
-
-
Alvarez-Breckenridge, C.A.1
Yu, J.2
Price, R.3
-
81
-
-
43149097365
-
Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells
-
Khan AN, Gregorie CJ, Tomasi TB. Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells. Cancer Immunol Immunother. 2008;57(5):647–654.
-
(2008)
Cancer Immunol Immunother
, vol.57
, Issue.5
, pp. 647-654
-
-
Khan, A.N.1
Gregorie, C.J.2
Tomasi, T.B.3
-
82
-
-
80052420081
-
Immunological effects of low-dose cyclophosphamide in cancer patients treated with oncolytic adenovirus
-
Cerullo V, Diaconu I, Kangasniemi L, et al. Immunological effects of low-dose cyclophosphamide in cancer patients treated with oncolytic adenovirus. Mol Ther. 2011;19(9):1737–1746.
-
(2011)
Mol Ther
, vol.19
, Issue.9
, pp. 1737-1746
-
-
Cerullo, V.1
Diaconu, I.2
Kangasniemi, L.3
-
83
-
-
84857723974
-
VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression
-
Doloff JC, Waxman DJ. VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression. Cancer Res. 2012;72(5):1103–1115.
-
(2012)
Cancer Res
, vol.72
, Issue.5
, pp. 1103-1115
-
-
Doloff, J.C.1
Waxman, D.J.2
-
84
-
-
45749096230
-
Treg depletion-enhanced IL-2 treatment facilitates therapy of established tumors using systemically delivered oncolytic virus
-
Kottke T, Galivo F, Wongthida P, et al. Treg depletion-enhanced IL-2 treatment facilitates therapy of established tumors using systemically delivered oncolytic virus. Mol Ther. 2008;16(7):1217–1226.
-
(2008)
Mol Ther
, vol.16
, Issue.7
, pp. 1217-1226
-
-
Kottke, T.1
Galivo, F.2
Wongthida, P.3
-
85
-
-
33847368549
-
Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
-
Ghiringhelli F, Menard C, Puig PE, et al. Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients. Cancer Immunol Immunother. 2007;56(5):641–648.
-
(2007)
Cancer Immunol Immunother
, vol.56
, Issue.5
, pp. 641-648
-
-
Ghiringhelli, F.1
Menard, C.2
Puig, P.E.3
-
86
-
-
84873097527
-
Enhanced antitumoral activity of oncolytic herpes simplex virus with gemcitabine using colorectal tumor models
-
Esaki S, Goshima F, Kimura H, Murakami S, Nishiyama Y. Enhanced antitumoral activity of oncolytic herpes simplex virus with gemcitabine using colorectal tumor models. Int J Cancer. 2013;132(7):1592–1601.
-
(2013)
Int J Cancer
, vol.132
, Issue.7
, pp. 1592-1601
-
-
Esaki, S.1
Goshima, F.2
Kimura, H.3
Murakami, S.4
Nishiyama, Y.5
-
87
-
-
84904694379
-
Chemotherapy and oncolytic virotherapy: Advanced tactics in the war against cancer
-
Nguyen A, Ho L, Wan Y. Chemotherapy and oncolytic virotherapy: advanced tactics in the war against cancer. Front Oncol. 2014;4:145.
-
(2014)
Front Oncol
, vol.4
, pp. 145
-
-
Nguyen, A.1
Ho, L.2
Wan, Y.3
-
88
-
-
84858762241
-
Oncolytic virus and anti-4-1BB combination therapy elicits strong antitumor immunity against established cancer
-
John LB, Howland LJ, Flynn JK, et al. Oncolytic virus and anti-4-1BB combination therapy elicits strong antitumor immunity against established cancer. Cancer Res. 2012;72(7):1651–1660.
-
(2012)
Cancer Res
, vol.72
, Issue.7
, pp. 1651-1660
-
-
John, L.B.1
Howland, L.J.2
Flynn, J.K.3
-
89
-
-
84933526132
-
From virotherapy to oncolytic immunotherapy: Where are we now?
-
Coffin RS. From virotherapy to oncolytic immunotherapy: where are we now? Curr Opin Virol. 2015;13:93–100.
-
(2015)
Curr Opin Virol
, vol.13
, pp. 93-100
-
-
Coffin, R.S.1
-
90
-
-
84891825541
-
Immunogenic HSV-mediated oncolysis shapes the antitumor immune response and contributes to therapeutic efficacy
-
Workenhe ST, Simmons G, Pol JG, Lichty BD, Halford WP, Mossman KL. Immunogenic HSV-mediated oncolysis shapes the antitumor immune response and contributes to therapeutic efficacy. Mol Ther. 2014;22(1):123–131.
-
(2014)
Mol Ther
, vol.22
, Issue.1
, pp. 123-131
-
-
Workenhe, S.T.1
Simmons, G.2
Pol, J.G.3
Lichty, B.D.4
Halford, W.P.5
Mossman, K.L.6
-
91
-
-
84959432143
-
Cytotoxic Activity Against Human Neuroblastoma and Melanoma Cells Mediated by IgM Antibodies Derived from Peripheral Blood of Healthy Donors
-
Feb 23
-
Devarapu SK, Mamidi S, Plöger F, Dill O, Blixt O, Kirschfink M, Schwartz-Albiez R. Cytotoxic Activity Against Human Neuroblastoma and Melanoma Cells Mediated by IgM Antibodies Derived from Peripheral Blood of Healthy Donors. Int J Cancer. Epub 2016 Feb 23.
-
(2016)
Int J Cancer. Epub
-
-
Devarapu, S.K.1
Mamidi, S.2
Plöger, F.3
Dill, O.4
Blixt, O.5
Kirschfink, M.6
Schwartz-Albiez, R.7
|