-
1
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
PMID:20525992
-
Hodi FS, O’Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363:711-23; PMID:20525992; http://dx.doi.org/10.1056/NEJMoa1003466
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O’Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
-
2
-
-
84884594361
-
OptiM: A randomized phase III trial of talimogene laherparepvec (T-VEC) versus subcutaneous (SC) granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment (tx) of unresected stage IIIB/C and IV melanoma
-
(suppl; abstr LBA9008)
-
Andtbacka RHI, Collichio FA, Amatruda T, Senzer NN, Chesney J, Delman KA, Spitler LE, Puzanov I, Doleman S, Ye Y et al. OptiM: a randomized phase III trial of talimogene laherparepvec (T-VEC) versus subcutaneous (SC) granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment (tx) of unresected stage IIIB/C and IV melanoma. J Clin Oncol 2013; 31 (suppl; abstr LBA9008).
-
(2013)
J Clin Oncol
, pp. 31
-
-
Andtbacka, R.1
Collichio, F.A.2
Amatruda, T.3
Senzer, N.N.4
Chesney, J.5
Delman, K.A.6
Spitler, L.E.7
Puzanov, I.8
Doleman, S.9
Ye, Y.10
-
3
-
-
84875225339
-
Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer
-
PMID:23396206
-
Heo J, Reid T, Ruo L, Breitbach CJ, Rose S, Bloomston M, Cho M, Lim HY, Chung HC, Kim CW et al. Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer. Nat Med 2013; 19:329-36; PMID:23396206; http://dx.doi.org/10.1038/nm.3089
-
(2013)
Nat Med
, vol.19
, pp. 329-336
-
-
Heo, J.1
Reid, T.2
Ruo, L.3
Breitbach, C.J.4
Rose, S.5
Bloomston, M.6
Cho, M.7
Lim, H.Y.8
Chung, H.C.9
Kim, C.W.10
-
4
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
PMID:20818862
-
Kantoff PW, Higano CS, Shore ND, Berger ER, Small EJ, Penson DF, Redfern CH, Ferrari AC, Dreicer R, Sims RB et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010; 363:411-22; PMID:20818862; http://dx.doi.org/10.1056/NEJMoa1001294
-
(2010)
N Engl J Med
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
Berger, E.R.4
Small, E.J.5
Penson, D.F.6
Redfern, C.H.7
Ferrari, A.C.8
Dreicer, R.9
Sims, R.B.10
-
5
-
-
84876325876
-
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
-
PMID:23527958
-
Grupp SA, Kalos M, Barrett D, Aplenc R, Porter DL, Rheingold SR, Teachey DT, Chew A, Hauck B, Wright JF et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N Engl J Med 2013; 368:1509-18; PMID:23527958; http://dx.doi.org/10.1056/NEJMoa1215134
-
(2013)
N Engl J Med
, vol.368
, pp. 1509-1518
-
-
Grupp, S.A.1
Kalos, M.2
Barrett, D.3
Aplenc, R.4
Porter, D.L.5
Rheingold, S.R.6
Teachey, D.T.7
Chew, A.8
Hauck, B.9
Wright, J.F.10
-
7
-
-
73149092567
-
Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
-
PMID:19934295
-
Wolchok JD, Hoos A, O’Day S, Weber JS, Hamid O, Lebbe C, Maio M, Binder M, Bohnsack O, Nichol G et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res 2009; 15:7412-20; PMID:19934295; http://dx.doi.org/10.1158/1078-0432.CCR-09-1624
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7412-7420
-
-
Wolchok, J.D.1
Hoos, A.2
O’Day, S.3
Weber, J.S.4
Hamid, O.5
Lebbe, C.6
Maio, M.7
Binder, M.8
Bohnsack, O.9
Nichol, G.10
-
8
-
-
84892365940
-
Checkpoint blocking antibodies in cancer immunotherapy
-
PMID:24161671
-
Kyi C, Postow MA. Checkpoint blocking antibodies in cancer immunotherapy. FEBS Lett 2014; 588:368-76; PMID:24161671; http://dx.doi.org/10.1016/j.febslet.2013.10.015
-
(2014)
FEBS Lett
, vol.588
, pp. 368-376
-
-
Kyi, C.1
Postow, M.A.2
-
9
-
-
77952298772
-
HMGB1 and RAGE in inflammation and cancer
-
PMID:20192808
-
Sims GP, Rowe DC, Rietdijk ST, Herbst R, Coyle AJ. HMGB1 and RAGE in inflammation and cancer. Ann Rev Immunol 2010; 28:367-88; PMID:20192808; http://dx.doi.org/10.1146/annurev.immunol.021908.132603
-
(2010)
Ann Rev Immunol
, vol.28
, pp. 367-388
-
-
Sims, G.P.1
Rowe, D.C.2
Rietdijk, S.T.3
Herbst, R.4
Coyle, A.J.5
-
10
-
-
84881231803
-
HMGB1 in cancer: Good, bad, or both?
-
PMID:23723299
-
Kang R, Zhang Q, Zeh HJ, Lotze MT, Tang D. HMGB1 in cancer: good, bad, or both? Clin Cancer Res 2013; 19:4046-57; PMID:23723299; http://dx.doi.org/10.1158/1078-0432.CCR-13-0495
-
(2013)
Clin Cancer Res
, vol.19
, pp. 4046-4057
-
-
Kang, R.1
Zhang, Q.2
Zeh, H.J.3
Lotze, M.T.4
Tang, D.5
-
11
-
-
35748942876
-
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy
-
PMID:17979839
-
Apetoh L, Ghiringhelli F, Tesniere A, Criollo A, Ortiz C, Lidereau R, Mariette C, Chaput N, Mira JP, Delaloge S et al. The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy. Immunol Rev 2007; 220:47-59; PMID:17979839; http://dx.doi.org/10.1111/j.1600-065X.2007.00573.x
-
(2007)
Immunol Rev
, vol.220
, pp. 47-59
-
-
Apetoh, L.1
Ghiringhelli, F.2
Tesniere, A.3
Criollo, A.4
Ortiz, C.5
Lidereau, R.6
Mariette, C.7
Chaput, N.8
Mira, J.P.9
Delaloge, S.10
-
12
-
-
84879651810
-
Life after death: Targeting high mobility group box 1 in emergent cancer therapies
-
PMID:23359863
-
Guo ZS, Liu Z, Bartlett DL, Tang D, Lotze MT. Life after death: targeting high mobility group box 1 in emergent cancer therapies. Am J Cancer Res 2013; 3:1-20; PMID:23359863
-
(2013)
Am J Cancer Res
, vol.3
, pp. 1-20
-
-
Guo, Z.S.1
Liu, Z.2
Bartlett, D.L.3
Tang, D.4
Lotze, M.T.5
-
13
-
-
84874943967
-
Immunogenic cell death biomarkers HMGB1, RAGE, and DNAse indicate response to radioembolization therapy and prognosis in colorectal cancer patients
-
PMID:23047645
-
Fahmueller YN, Nagel D, Hoffmann RT, Tatsch K, Jakobs T, Stieber P, Holdenrieder S. Immunogenic cell death biomarkers HMGB1, RAGE, and DNAse indicate response to radioembolization therapy and prognosis in colorectal cancer patients. Int J Cancer 2013; 132:2349-58; PMID:23047645; http://dx.doi.org/10.1002/ijc.27894
-
(2013)
Int J Cancer
, vol.132
, pp. 2349-2358
-
-
Fahmueller, Y.N.1
Nagel, D.2
Hoffmann, R.T.3
Tatsch, K.4
Jakobs, T.5
Stieber, P.6
Holdenrieder, S.7
-
14
-
-
84884909735
-
Circulating nucleosomes and immunogenic cell death markers HMGB1, sRAGE and DNAse in patients with advanced pancreatic cancer undergoing chemotherapy
-
PMID:23729200
-
Wittwer C, Boeck S, Heinemann V, Haas M, Stieber P, Nagel D, Holdenrieder S. Circulating nucleosomes and immunogenic cell death markers HMGB1, sRAGE and DNAse in patients with advanced pancreatic cancer undergoing chemotherapy. Int J Cancer 2013; 133:2619-30; PMID:23729200
-
(2013)
Int J Cancer
, vol.133
, pp. 2619-2630
-
-
Wittwer, C.1
Boeck, S.2
Heinemann, V.3
Haas, M.4
Stieber, P.5
Nagel, D.6
Holdenrieder, S.7
-
15
-
-
84872798053
-
Circulating immunogenic cell death biomarkers HMGB1 and RAGE in breast cancer patients during neoadjuvant chemotherapy
-
PMID:22983919
-
Stoetzer OJ, Fersching DM, Salat C, Steinkohl O, Gabka CJ, Hamann U, Braun M, Feller AM, Heinemann V, Siegele B et al. Circulating immunogenic cell death biomarkers HMGB1 and RAGE in breast cancer patients during neoadjuvant chemotherapy. Tumour Biol 2013; 34:81-90; PMID:22983919; http://dx.doi.org/10.1007/s13277-012-0513-1
-
(2013)
Tumour Biol
, vol.34
, pp. 81-90
-
-
Stoetzer, O.J.1
Fersching, D.M.2
Salat, C.3
Steinkohl, O.4
Gabka, C.J.5
Hamann, U.6
Braun, M.7
Feller, A.M.8
Heinemann, V.9
Siegele, B.10
-
16
-
-
84873268694
-
Overexpression of high mobility group box 1 with poor prognosis in patients after radical prostatectomy
-
PMID:22672360
-
Li T, Gui Y, Yuan T, Liao G, Bian C, Jiang Q, Huang S, Liu B, Wu D. Overexpression of high mobility group box 1 with poor prognosis in patients after radical prostatectomy. BJU Int 2012; 110:E1125-30; PMID:22672360; http://dx.doi.org/10.1111/j.1464-410X.2012.11277.x
-
(2012)
BJU Int
, vol.110
, pp. 1125-1130
-
-
Li, T.1
Gui, Y.2
Yuan, T.3
Liao, G.4
Bian, C.5
Jiang, Q.6
Huang, S.7
Liu, B.8
Wu, D.9
-
17
-
-
84880182469
-
Double-positive expression of high-mobility group box 1 and vascular endothelial growth factor C indicates a poorer prognosis in gastric cancer patients
-
PMID:23866030
-
He W, Tang B, Yang D, Li Y, Song W, Cheang T, Chen X, Li Y, Chen L, Zhan W et al. Double-positive expression of high-mobility group box 1 and vascular endothelial growth factor C indicates a poorer prognosis in gastric cancer patients. World J Surg Oncol 2013; 11:161; PMID:23866030; http://dx.doi.org/10.1186/1477-7819-11-161
-
(2013)
World J Surg Oncol
, vol.11
, pp. 161
-
-
He, W.1
Tang, B.2
Yang, D.3
Li, Y.4
Song, W.5
Cheang, T.6
Chen, X.7
Li, Y.8
Chen, L.9
Zhan, W.10
-
18
-
-
77953818716
-
Prognostic value of HMGB1 overexpression in resectable gastric adenocarcinomas
-
PMID:20579387
-
Bao G, Qiao Q, Zhao H, He X. Prognostic value of HMGB1 overexpression in resectable gastric adenocarcinomas. World J Surg Oncol 2010; 8:52; PMID:20579387; http://dx.doi.org/10.1186/1477-7819-8-52
-
(2010)
World J Surg Oncol
, vol.8
, pp. 52
-
-
Bao, G.1
Qiao, Q.2
Zhao, H.3
He, X.4
-
19
-
-
84890070353
-
Defective immunogenic cell death of HMGB1-deficient tumors: Compensatory therapy with TLR4 agonists
-
PMID:23811849
-
Yamazaki T, Hannani D, Poirier-Colame V, Ladoire S, Locher C, Sistigu A, Prada N, Adjemian S, Catani JP, Freudenberg M et al. Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists. Cell Death Differ 2014; 21:69-78; PMID:23811849; http://dx.doi.org/10.1038/cdd.2013.72
-
(2014)
Cell Death Differ
, vol.21
, pp. 69-78
-
-
Yamazaki, T.1
Hannani, D.2
Poirier-Colame, V.3
Ladoire, S.4
Locher, C.5
Sistigu, A.6
Prada, N.7
Adjemian, S.8
Catani, J.P.9
Freudenberg, M.10
-
20
-
-
33646240157
-
Pediatric cancers are infiltrated predominantly by macrophages and contain a paucity of dendritic cells: A major nosologic difference with adult tumors
-
PMID:16609014
-
Vakkila J, Jaffe R, Michelow M, Lotze MT. Pediatric cancers are infiltrated predominantly by macrophages and contain a paucity of dendritic cells: a major nosologic difference with adult tumors. Clin Cancer Res 2006; 12:2049-54; PMID:16609014; http://dx.doi.org/10.1158/1078-0432.CCR-05-1824
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2049-2054
-
-
Vakkila, J.1
Jaffe, R.2
Michelow, M.3
Lotze, M.T.4
-
21
-
-
84878074018
-
Antiviral and antitumor T-cell immunity in patients treated with GM-CSF-coding oncolytic adenovirus
-
PMID:23493351
-
Kanerva A, Nokisalmi P, Diaconu I, Koski A, Cerullo V, Liikanen I, Tahtinen S, Oksanen M, Heiskanen R, Pesonen S et al. Antiviral and antitumor T-cell immunity in patients treated with GM-CSF-coding oncolytic adenovirus. Clin Cancer Res 2013; 19:2734-44; PMID:23493351; http://dx.doi.org/10.1158/1078-0432.CCR-12-2546
-
(2013)
Clin Cancer Res
, vol.19
, pp. 2734-2744
-
-
Kanerva, A.1
Nokisalmi, P.2
Diaconu, I.3
Koski, A.4
Cerullo, V.5
Liikanen, I.6
Tahtinen, S.7
Oksanen, M.8
Heiskanen, R.9
Pesonen, S.10
-
22
-
-
84878530852
-
Oncolytic adenovirus with temozolomide induces autophagy and antitumor immune responses in cancer patients
-
PMID:23546299
-
Liikanen I, Ahtiainen L, Hirvinen ML, Bramante S, Cerullo V, Nokisalmi P, Hemminki O, Diaconu I, Pesonen S, Koski A et al. Oncolytic adenovirus with temozolomide induces autophagy and antitumor immune responses in cancer patients. Mol Ther 2013; 21:1212-23; PMID:23546299; http://dx.doi.org/10.1038/mt.2013.51
-
(2013)
Mol Ther
, vol.21
, pp. 1212-1223
-
-
Liikanen, I.1
Ahtiainen, L.2
Hirvinen, M.L.3
Bramante, S.4
Cerullo, V.5
Nokisalmi, P.6
Hemminki, O.7
Diaconu, I.8
Pesonen, S.9
Koski, A.10
-
23
-
-
77954899030
-
Phase I study of single-agent antiprogrammed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
PMID:20516446
-
Brahmer JR, Drake CG, Wollner I, Powderly JD, Picus J, Sharfman WH, Stankevich E, Pons A, Salay TM, McMiller TL et al. Phase I study of single-agent antiprogrammed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol 2010; 28:3167-75; PMID:20516446; http://dx.doi.org/10.1200/JCO.2009.26.7609
-
(2010)
J Clin Oncol
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
Powderly, J.D.4
Picus, J.5
Sharfman, W.H.6
Stankevich, E.7
Pons, A.8
Salay, T.M.9
McMiller, T.L.10
-
25
-
-
78049416842
-
MHC-restricted fratricide of human lymphocytes expressing survivinspecific transgenic T cell receptors
-
PMID:20978348
-
Leisegang M, Wilde S, Spranger S, Milosevic S, Frankenberger B, Uckert W, Schendel DJ. MHC-restricted fratricide of human lymphocytes expressing survivinspecific transgenic T cell receptors. J Clin Invest 2010; 120:3869-77; PMID:20978348; http://dx.doi.org/10.1172/JCI43437
-
(2010)
J Clin Invest
, vol.120
, pp. 3869-3877
-
-
Leisegang, M.1
Wilde, S.2
Spranger, S.3
Milosevic, S.4
Frankenberger, B.5
Uckert, W.6
Schendel, D.J.7
-
26
-
-
77957571590
-
Treatment of cancer patients with a serotype 5/3 chimeric oncolytic adenovirus expressing GMCSF
-
PMID:20664527
-
Koski A, Kangasniemi L, Escutenaire S, Pesonen S, Cerullo V, Diaconu I, Nokisalmi P, Raki M, Rajecki M, Guse K et al. Treatment of cancer patients with a serotype 5/3 chimeric oncolytic adenovirus expressing GMCSF. Mol Ther 2010; 18:1874-84; PMID:20664527; http://dx.doi.org/10.1038/mt.2010.161
-
(2010)
Mol Ther
, vol.18
, pp. 1874-1884
-
-
Koski, A.1
Kangasniemi, L.2
Escutenaire, S.3
Pesonen, S.4
Cerullo, V.5
Diaconu, I.6
Nokisalmi, P.7
Raki, M.8
Rajecki, M.9
Guse, K.10
-
27
-
-
77953083925
-
Oncolytic adenovirus ICOVIR-7 in patients with advanced and refractory solid tumors
-
PMID:20501623
-
Nokisalmi P, Pesonen S, Escutenaire S, Sarkioja M, Raki M, Cerullo V, Laasonen L, Alemany R, Rojas J, Cascallo M et al. Oncolytic adenovirus ICOVIR-7 in patients with advanced and refractory solid tumors. Clin Cancer Res 2010; 16:3035-43; PMID:20501623; http://dx.doi.org/10.1158/1078-0432.CCR-09-3167
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3035-3043
-
-
Nokisalmi, P.1
Pesonen, S.2
Escutenaire, S.3
Sarkioja, M.4
Raki, M.5
Cerullo, V.6
Laasonen, L.7
Alemany, R.8
Rojas, J.9
Cascallo, M.10
-
28
-
-
80052420081
-
Immunological effects of low-dose cyclophosphamide in cancer patients treated with oncolytic adenovirus
-
PMID:21673660
-
Cerullo V, Diaconu I, Kangasniemi L, Rajecki M, Escutenaire S, Koski A, Romano V, Rouvinen N, Tuuminen T, Laasonen L et al. Immunological effects of low-dose cyclophosphamide in cancer patients treated with oncolytic adenovirus. Mol Ther 2011; 19:1737-46; PMID:21673660; http://dx.doi.org/10.1038/mt.2011.113
-
(2011)
Mol Ther
, vol.19
, pp. 1737-1746
-
-
Cerullo, V.1
Diaconu, I.2
Kangasniemi, L.3
Rajecki, M.4
Escutenaire, S.5
Koski, A.6
Romano, V.7
Rouvinen, N.8
Tuuminen, T.9
Laasonen, L.10
-
29
-
-
84857505900
-
Integrin targeted oncolytic adenoviruses Ad5-D24-RGD and Ad5-RGD-D24-GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors
-
PMID:21630267
-
Pesonen S, Diaconu I, Cerullo V, Escutenaire S, Raki M, Kangasniemi L, Nokisalmi P, Dotti G, Guse K, Laasonen L et al. Integrin targeted oncolytic adenoviruses Ad5-D24-RGD and Ad5-RGD-D24-GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors. Int J Cancer 2012; 130:1937-47; PMID:21630267; http://dx.doi.org/10.1002/ijc.26216
-
(2012)
Int J Cancer
, vol.130
, pp. 1937-1947
-
-
Pesonen, S.1
Diaconu, I.2
Cerullo, V.3
Escutenaire, S.4
Raki, M.5
Kangasniemi, L.6
Nokisalmi, P.7
Dotti, G.8
Guse, K.9
Laasonen, L.10
-
30
-
-
84859376777
-
Oncolytic immunotherapy of advanced solid tumors with a CD40L-expressing replicating adenovirus: Assessment of safety and immunologic responses in patients
-
PMID:22323527
-
Pesonen S, Diaconu I, Kangasniemi L, Ranki T, Kanerva A, Pesonen SK, Gerdemann U, Leen AM, Kairemo K, Oksanen M et al. Oncolytic immunotherapy of advanced solid tumors with a CD40L-expressing replicating adenovirus: assessment of safety and immunologic responses in patients. Cancer Res 2012; 72:1621-31; PMID:22323527; http://dx.doi.org/10.1158/0008-5472.CAN-11-3001
-
(2012)
Cancer Res
, vol.72
, pp. 1621-1631
-
-
Pesonen, S.1
Diaconu, I.2
Kangasniemi, L.3
Ranki, T.4
Kanerva, A.5
Pesonen, S.K.6
Gerdemann, U.7
Leen, A.M.8
Kairemo, K.9
Oksanen, M.10
-
31
-
-
84867037132
-
Ad3-hTERT-E1A, a fully serotype 3 oncolytic adenovirus, in patients with chemotherapy refractory cancer
-
PMID:22871667
-
Hemminki O, Diaconu I, Cerullo V, Pesonen SK, Kanerva A, Joensuu T, Kairemo K, Laasonen L, Partanen K, Kangasniemi L et al. Ad3-hTERT-E1A, a fully serotype 3 oncolytic adenovirus, in patients with chemotherapy refractory cancer. Mol Ther 2012; 20:1821-30; PMID:22871667; http://dx.doi.org/10.1038/mt.2012.115
-
(2012)
Mol Ther
, vol.20
, pp. 1821-1830
-
-
Hemminki, O.1
Diaconu, I.2
Cerullo, V.3
Pesonen, S.K.4
Kanerva, A.5
Joensuu, T.6
Kairemo, K.7
Laasonen, L.8
Partanen, K.9
Kangasniemi, L.10
-
32
-
-
84896753600
-
Interleukin-6 cytokine: A multifunctional glycoprotein for cancer
-
PMID:24078831
-
Zarogoulidis P, Yarmus L, Darwiche K, Walter R, Huang H, Li Z, Zaric B, Tsakiridis K, Zarogoulidis K. Interleukin-6 cytokine: a multifunctional glycoprotein for cancer. Immunome Res 2013; 9:16535; PMID:24078831
-
(2013)
Immunome Res
, vol.9
, pp. 16535
-
-
Zarogoulidis, P.1
Yarmus, L.2
Darwiche, K.3
Walter, R.4
Huang, H.5
Li, Z.6
Zaric, B.7
Tsakiridis, K.8
Zarogoulidis, K.9
-
33
-
-
20144376844
-
Stat3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects
-
PMID:15778348
-
Burdelya L, Kujawski M, Niu G, Zhong B, Wang T, Zhang S, Kortylewski M, Shain K, Kay H, Djeu J et al. Stat3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects. J Immunol 2005; 174:3925-31; PMID:15778348; http://dx.doi.org/10.4049/jimmunol.174.7.3925
-
(2005)
J Immunol
, vol.174
, pp. 3925-3931
-
-
Burdelya, L.1
Kujawski, M.2
Niu, G.3
Zhong, B.4
Wang, T.5
Zhang, S.6
Kortylewski, M.7
Shain, K.8
Kay, H.9
Djeu, J.10
-
34
-
-
84879607460
-
HMGB1 recruits myeloid derived suppressor cells to promote peritoneal dissemination of colon cancer after resection
-
PMID:23707808
-
Li W, Wu K, Zhao E, Shi L, Li R, Zhang P, Yin Y, Shuai X, Wang G, Tao K. HMGB1 recruits myeloid derived suppressor cells to promote peritoneal dissemination of colon cancer after resection. Biochem Biophys Res Commun 2013; 436:156-61; PMID:23707808; http://dx.doi.org/10.1016/j.bbrc.2013.04.109
-
(2013)
Biochem Biophys Res Commun
, vol.436
, pp. 156-161
-
-
Li, W.1
Wu, K.2
Zhao, E.3
Shi, L.4
Li, R.5
Zhang, P.6
Yin, Y.7
Shuai, X.8
Wang, G.9
Tao, K.10
-
35
-
-
79960387864
-
Knockdown of HMGB1 in tumor cells attenuates their ability to induce regulatory T cells and uncovers naturally acquired CD8 T celldependent antitumor immunity
-
PMID:21642542
-
Liu Z, Falo LD, Jr., You Z. Knockdown of HMGB1 in tumor cells attenuates their ability to induce regulatory T cells and uncovers naturally acquired CD8 T celldependent antitumor immunity. J Immunol 2011; 187:118-25; PMID:21642542; http://dx.doi.org/10.4049/jimmunol.1003378
-
(2011)
J Immunol
, vol.187
, pp. 118-125
-
-
Liu, Z.1
Falo, L.D.2
You, Z.3
-
36
-
-
84977139455
-
Immunoglobulin-like transcript 2 (ILT2) is a biomarker of therapeutic response to oncolytic immunotherapy with vaccinia viruses
-
PMID:24829758
-
Zloza A, Kim DW, Kim-Schulze S, Jagoda MC, Monsurro V, Marincola FM, Kaufman HL. Immunoglobulin-like transcript 2 (ILT2) is a biomarker of therapeutic response to oncolytic immunotherapy with vaccinia viruses. J Immun Cancer 2014; 2:1; PMID:24829758; http://dx.doi.org/10.1186/2051-1426-2-1
-
(2014)
J Immun Cancer
, vol.2
, pp. 1
-
-
Zloza, A.1
Kim, D.W.2
Kim-Schulze, S.3
Jagoda, M.C.4
Monsurro, V.5
Marincola, F.M.6
Kaufman, H.L.7
-
37
-
-
84872872011
-
Dynamics of T-cell infiltration during the course of ovarian cancer: The gradual shift from a Th17 effector cell response to a predominant infiltration by regulatory T-cells
-
PMID:22865582
-
Fialova A, Partlova S, Sojka L, Hromadkova H, Brtnicky T, Fucikova J, Kocian P, Rob L, Bartunkova J, Spisek R. Dynamics of T-cell infiltration during the course of ovarian cancer: the gradual shift from a Th17 effector cell response to a predominant infiltration by regulatory T-cells. Int J Cancer 2013; 132:1070-9; PMID:22865582; http://dx.doi.org/10.1002/ijc.27759
-
(2013)
Int J Cancer
, vol.132
, pp. 1070-1079
-
-
Fialova, A.1
Partlova, S.2
Sojka, L.3
Hromadkova, H.4
Brtnicky, T.5
Fucikova, J.6
Kocian, P.7
Rob, L.8
Bartunkova, J.9
Spisek, R.10
-
38
-
-
84860520650
-
Immune response is an important aspect of the antitumor effect produced by a CD40L-encoding oncolytic adenovirus
-
PMID:22396493
-
Diaconu I, Cerullo V, Hirvinen ML, Escutenaire S, Ugolini M, Pesonen SK, Bramante S, Parviainen S, Kanerva A, Loskog AS et al. Immune response is an important aspect of the antitumor effect produced by a CD40L-encoding oncolytic adenovirus. Cancer Res 2012; 72:2327-38; PMID:22396493; http://dx.doi.org/10.1158/0008-5472.CAN-11-2975
-
(2012)
Cancer Res
, vol.72
, pp. 2327-2338
-
-
Diaconu, I.1
Cerullo, V.2
Hirvinen, M.L.3
Escutenaire, S.4
Ugolini, M.5
Pesonen, S.K.6
Bramante, S.7
Parviainen, S.8
Kanerva, A.9
Loskog, A.S.10
-
39
-
-
70349982431
-
HMGB1 mediates endogenous TLR2 activation and brain tumor regression
-
PMID:19143470
-
Curtin JF, Liu N, Candolfi M, Xiong W, Assi H, Yagiz K, Edwards MR, Michelsen KS, Kroeger KM, Liu C et al. HMGB1 mediates endogenous TLR2 activation and brain tumor regression. PLoS Med 2009; 6:e10; PMID:19143470
-
(2009)
Plos Med
, vol.6
-
-
Curtin, J.F.1
Liu, N.2
Candolfi, M.3
Xiong, W.4
Assi, H.5
Yagiz, K.6
Edwards, M.R.7
Michelsen, K.S.8
Kroeger, K.M.9
Liu, C.10
-
40
-
-
26944496117
-
Statistics Subcommittee of the NCIEWGoCD. REporting recommendations for tumor MARKer prognostic studies (REMARK)
-
PMID:16130938
-
McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM. Statistics Subcommittee of the NCIEWGoCD. REporting recommendations for tumor MARKer prognostic studies (REMARK). Nat Clin Pract Oncol 2005; 2:416-22; PMID:16130938; http://dx.doi.org/10.1038/ncponc0252
-
(2005)
Nat Clin Pract Oncol
, vol.2
, pp. 416-422
-
-
McShane, L.M.1
Altman, D.G.2
Sauerbrei, W.3
Taube, S.E.4
Gion, M.5
Clark, G.M.6
-
41
-
-
84890519990
-
[(18)F]-fluorodeoxyglucose positron emission tomography and computed tomography in response evaluation of oncolytic adenovirus treatments of patients with advanced cancer
-
PMID:24099555
-
Koski A, Ahtinen H, Liljenback H, Roivainen A, Koskela A, Oksanen M, Partanen K, Laasonen L, Kairemo K, Joensuu T et al. [(18)F]-fluorodeoxyglucose positron emission tomography and computed tomography in response evaluation of oncolytic adenovirus treatments of patients with advanced cancer. Hum Gene Ther 2013; 24:1029-41; PMID:24099555; http://dx.doi.org/10.1089/hum.2013.123
-
(2013)
Hum Gene Ther
, vol.24
, pp. 1029-1041
-
-
Koski, A.1
Ahtinen, H.2
Liljenback, H.3
Roivainen, A.4
Koskela, A.5
Oksanen, M.6
Partanen, K.7
Laasonen, L.8
Kairemo, K.9
Joensuu, T.10
-
42
-
-
77954530690
-
Prolonged systemic circulation of chimeric oncolytic adenovirus Ad5/3-Cox2L-D24 in patients with metastatic and refractory solid tumors
-
PMID:20237509
-
Pesonen S, Nokisalmi P, Escutenaire S, Sarkioja M, Raki M, Cerullo V, Kangasniemi L, Laasonen L, Ribacka C, Guse K et al. Prolonged systemic circulation of chimeric oncolytic adenovirus Ad5/3-Cox2L-D24 in patients with metastatic and refractory solid tumors. Gene Ther 2010; 17:892-904; PMID:20237509; http://dx.doi.org/10.1038/gt.2010.17
-
(2010)
Gene Ther
, vol.17
, pp. 892-904
-
-
Pesonen, S.1
Nokisalmi, P.2
Escutenaire, S.3
Sarkioja, M.4
Raki, M.5
Cerullo, V.6
Kangasniemi, L.7
Laasonen, L.8
Ribacka, C.9
Guse, K.10
-
43
-
-
77953160443
-
Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients
-
PMID:20484030
-
Cerullo V, Pesonen S, Diaconu I, Escutenaire S, Arstila PT, Ugolini M, Nokisalmi P, Raki M, Laasonen L, Sarkioja M et al. Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients. Cancer Res 2010; 70:4297-309; PMID:20484030; http://dx.doi.org/10.1158/0008-5472.CAN-09-3567
-
(2010)
Cancer Res
, vol.70
, pp. 4297-4309
-
-
Cerullo, V.1
Pesonen, S.2
Diaconu, I.3
Escutenaire, S.4
Arstila, P.T.5
Ugolini, M.6
Nokisalmi, P.7
Raki, M.8
Laasonen, L.9
Sarkioja, M.10
-
44
-
-
79952901914
-
Oncolytic adenovirus based on serotype 3
-
PMID:21183947
-
Hemminki O, Bauerschmitz G, Hemmi S, Lavilla-Alonso S, Diaconu I, Guse K, Koski A, Desmond RA, Lappalainen M, Kanerva A et al. Oncolytic adenovirus based on serotype 3. Cancer Gene Ther 2010; 18:288-96; PMID:21183947; http://dx.doi.org/10.1038/cgt.2010.79
-
(2010)
Cancer Gene Ther
, vol.18
, pp. 288-296
-
-
Hemminki, O.1
Bauerschmitz, G.2
Hemmi, S.3
Lavilla-Alonso, S.4
Diaconu, I.5
Guse, K.6
Koski, A.7
Desmond, R.A.8
Lappalainen, M.9
Kanerva, A.10
-
45
-
-
84857853704
-
SPECT/CT imaging of hNIS-expression after intravenous delivery of an oncolytic adenovirus and 131I
-
PMID:22412937
-
Rajecki M, Sarparanta M, Hakkarainen T, Tenhunen M, Diaconu I, Kuhmonen V, Kairemo K, Kanerva A, Airaksinen AJ, Hemminki A. SPECT/CT imaging of hNIS-expression after intravenous delivery of an oncolytic adenovirus and 131I. PloS One 2012; 7:e32871; PMID:22412937; http://dx.doi.org/10.1371/journal.pone.0032871
-
(2012)
Plos One
, vol.7
-
-
Rajecki, M.1
Sarparanta, M.2
Hakkarainen, T.3
Tenhunen, M.4
Diaconu, I.5
Kuhmonen, V.6
Kairemo, K.7
Kanerva, A.8
Airaksinen, A.J.9
Hemminki, A.10
-
46
-
-
84876144943
-
CSF high-mobility group box 1 is associated with intrathecal inflammation and astrocytic damage in neuromyelitis optica
-
PMID:23255728
-
Uzawa A, Mori M, Masuda S, Muto M, Kuwabara S. CSF high-mobility group box 1 is associated with intrathecal inflammation and astrocytic damage in neuromyelitis optica. J Neurol Neurosurg Psychiatry 2013; 84:517-22; PMID:23255728; http://dx.doi.org/10.1136/jnnp-2012-304039
-
(2013)
J Neurol Neurosurg Psychiatry
, vol.84
, pp. 517-522
-
-
Uzawa, A.1
Mori, M.2
Masuda, S.3
Muto, M.4
Kuwabara, S.5
-
47
-
-
56249117683
-
High mobility group box 1 (HMGB1) and macrophage migration inhibitory factor (MIF) in Kawasaki disease
-
PMID:18720262
-
Hoshina T, Kusuhara K, Ikeda K, Mizuno Y, Saito M, Hara T. High mobility group box 1 (HMGB1) and macrophage migration inhibitory factor (MIF) in Kawasaki disease. Scand J Rheumatol 2008; 37:445-9; PMID:18720262; http://dx.doi.org/10.1080/03009740802144143
-
(2008)
Scand J Rheumatol
, vol.37
, pp. 445-449
-
-
Hoshina, T.1
Kusuhara, K.2
Ikeda, K.3
Mizuno, Y.4
Saito, M.5
Hara, T.6
-
48
-
-
84861489009
-
Methodological and preanalytical evaluation of an HMGB1 immunoassay
-
PMID:22593488
-
Lehner J, Wittwer C, Fersching D, Siegele B, Holdenrieder S, Stoetzer OJ. Methodological and preanalytical evaluation of an HMGB1 immunoassay. Anticancer Res 2012; 32:2059-62; PMID:22593488
-
(2012)
Anticancer Res
, vol.32
, pp. 2059-2062
-
-
Lehner, J.1
Wittwer, C.2
Fersching, D.3
Siegele, B.4
Holdenrieder, S.5
Stoetzer, O.J.6
-
49
-
-
79951569626
-
In vivo and in vitro distribution of type 5 and fiber-modified oncolytic adenoviruses in human blood compartments
-
PMID:21261555
-
Escutenaire S, Cerullo V, Diaconu I, Ahtiainen L, Hannuksela P, Oksanen M, Haavisto E, Karioja-Kallio A, Holm SL, Kangasniemi L et al. In vivo and in vitro distribution of type 5 and fiber-modified oncolytic adenoviruses in human blood compartments. Ann Med 2011; 43:151-63; PMID:21261555; http://dx.doi.org/10.3109/07853890.2010.538079
-
(2011)
Ann Med
, vol.43
, pp. 151-163
-
-
Escutenaire, S.1
Cerullo, V.2
Diaconu, I.3
Ahtiainen, L.4
Hannuksela, P.5
Oksanen, M.6
Haavisto, E.7
Karioja-Kallio, A.8
Holm, S.L.9
Kangasniemi, L.10
-
50
-
-
65549088863
-
Omental milky spots develop in the absence of lymphoid tissue-inducer cells and support B and T cell responses to peritoneal antigens
-
PMID:19427241
-
Rangel-Moreno J, Moyron-Quiroz JE, Carragher DM, Kusser K, Hartson L, Moquin A, Randall TD. Omental milky spots develop in the absence of lymphoid tissue-inducer cells and support B and T cell responses to peritoneal antigens. Immunity 2009; 30:731-43; PMID:19427241; http://dx.doi.org/10.1016/j.immuni.2009.03.014
-
(2009)
Immunity
, vol.30
, pp. 731-743
-
-
Rangel-Moreno, J.1
Moyron-Quiroz, J.E.2
Carragher, D.M.3
Kusser, K.4
Hartson, L.5
Moquin, A.6
Randall, T.D.7
|