Curcumin promotes autophagic survival of a subset of colon cancer stem cells, which are ablated by DCLK1-siRNA

Cancer Research

Volumn 74, Issue 9, 2014, Pages 2487-2498

  Kantara, Carla ^a   O'Connell, Malaney ^a   Sarkar, Shubhashish ^a   Moya, Stephanie ^a   Ullrich, Robert ^a   Singh, Pomila ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDHA1 PROTEIN; CELL MARKER; CURCUMIN; DCLK1 PROTEIN; HERMES ANTIGEN; LGR5 PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER STEM CELL; CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DCLK1 GENE; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR XENOGRAFT;

ANIMALS; ANTIGENS, CD44; ANTINEOPLASTIC AGENTS; AUTOPHAGY; CELL SURVIVAL; COLONIC NEOPLASMS; CURCUMIN; FEMALE; GENE KNOCKDOWN TECHNIQUES; HCT116 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, NUDE; MICE, SCID; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; SPHEROIDS, CELLULAR; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84900036041     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-3536     Document Type: Article

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