메뉴 건너뛰기




Volumn 21, Issue 4, 2014, Pages 371-378

Calpain-dependent clearance of the autophagy protein p62/SQSTM1 is a contributor to ΔpK oncolytic activity in melanoma

Author keywords

breast cancer; CSC; melanoma; ncolytic virotherapy; spheroid cultures

Indexed keywords

AUTOPHAGY PROTEIN 5; CALPASTATIN; CHLOROQUINE; ONCOLYTIC VIRUS; PD 150606; PROTEIN P62; UNCLASSIFIED DRUG; ACRYLIC ACID DERIVATIVE; CALPAIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SQSTM1 PROTEIN, HUMAN;

EID: 84897570280     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2014.6     Document Type: Article
Times cited : (20)

References (60)
  • 1
    • 27944433469 scopus 로고    scopus 로고
    • Oncolytic viral therapies-the clinical experience
    • Aghi M, Martuza RL. Oncolytic viral therapies-the clinical experience. Oncogene 2005; 24: 7802-7816.
    • (2005) Oncogene , vol.24 , pp. 7802-7816
    • Aghi, M.1    Martuza, R.L.2
  • 2
    • 63849225752 scopus 로고    scopus 로고
    • Human glioblastoma-derived cancer stem cells: Establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors
    • Wakimoto H, Kesari S, Farrell CJ, Curry Jr WT, Zaupa C, Aghi M et al. Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Res 2009; 69: 3472-3481.
    • (2009) Cancer Res , vol.69 , pp. 3472-3481
    • Wakimoto, H.1    Kesari, S.2    Farrell, C.J.3    Curry Jr., W.T.4    Zaupa, C.5    Aghi, M.6
  • 4
    • 79960314748 scopus 로고    scopus 로고
    • From cancer stem cells to tumor maintenance in melanoma
    • Fukunaga-Kalabis M, Roesch A, Herlyn M. From cancer stem cells to tumor maintenance in melanoma. J Invest Dermatol 2011; 131: 1600-1604.
    • (2011) J Invest Dermatol , vol.131 , pp. 1600-1604
    • Fukunaga-Kalabis, M.1    Roesch, A.2    Herlyn, M.3
  • 5
    • 78249250559 scopus 로고    scopus 로고
    • Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized
    • Quintana E, Shackleton M, Foster HR, Fullen DR, Sabel MS, Johnson TM et al. Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized. Cancer Cell 2010; 18: 510-523.
    • (2010) Cancer Cell , vol.18 , pp. 510-523
    • Quintana, E.1    Shackleton, M.2    Foster, H.R.3    Fullen, D.R.4    Sabel, M.S.5    Johnson, T.M.6
  • 6
    • 84862517728 scopus 로고    scopus 로고
    • Cancer stem cells: Current status and evolving complexities
    • Visvader JE, Lindeman GJ. Cancer stem cells: current status and evolving complexities. Cell Stem Cell 2012; 10: 717-728.
    • (2012) Cell Stem Cell , vol.10 , pp. 717-728
    • Visvader, J.E.1    Lindeman, G.J.2
  • 7
    • 84861373232 scopus 로고    scopus 로고
    • Effect of g34.5 deletions on oncolytic herpes simplex virus activity in brain tumors
    • Kanai R, Zaupa C, Sgubin D, Antoszczyk SJ, Martuza RL, Wakimoto H et al. Effect of g34.5 deletions on oncolytic herpes simplex virus activity in brain tumors. J Virol 2012; 86: 4420-4431.
    • (2012) J Virol , vol.86 , pp. 4420-4431
    • Kanai, R.1    Zaupa, C.2    Sgubin, D.3    Antoszczyk, S.J.4    Martuza, R.L.5    Wakimoto, H.6
  • 8
    • 84862976494 scopus 로고    scopus 로고
    • Active immunotherapy: Oncolytic virus therapy using HSV-1
    • Todo T. Active immunotherapy: oncolytic virus therapy using HSV-1. Adv Exp Med Biol 2012; 746: 178-186.
    • (2012) Adv Exp Med Biol , vol.746 , pp. 178-186
    • Todo, T.1
  • 9
    • 73349133717 scopus 로고    scopus 로고
    • Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma
    • Senzer NN, Kaufman HL, Amatruda T, Neumunaitis M, Daniels G, Gonzalez R et al. Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma. J Clin Oncol 2009; 27: 5763-5771.
    • (2009) J Clin Oncol , vol.27 , pp. 5763-5771
    • Senzer, N.N.1    Kaufman, H.L.2    Amatruda, T.3    Neumunaitis, M.4    Daniels, G.5    Gonzalez, R.6
  • 10
    • 84880376084 scopus 로고    scopus 로고
    • Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model
    • Cheema TA, Wakimoto H, Fecci PE, Ning J, Kuroda T, Jeyaretna DS et al. Multifaceted oncolytic virus therapy for glioblastoma in an immunocompetent cancer stem cell model. Proc Natl Acad Sci USA 2013; 110: 12006-12011.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 12006-12011
    • Cheema, T.A.1    Wakimoto, H.2    Fecci, P.E.3    Ning, J.4    Kuroda, T.5    Jeyaretna, D.S.6
  • 11
    • 58849117217 scopus 로고    scopus 로고
    • Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus
    • Mahller YY, Williams IP, Baird WH, Mitton B, Grossheim J, Saeki Y et al. Neuroblastoma cell lines contain pluripotent tumor initiating cells that are susceptible to a targeted oncolytic virus. PLoS One 2009; 4: e4235.
    • (2009) PLoS One , vol.4
    • Mahller, Y.Y.1    Williams, I.P.2    Baird, W.H.3    Mitton, B.4    Grossheim, J.5    Saeki, Y.6
  • 12
    • 84870203659 scopus 로고    scopus 로고
    • CD133 marks a myogenically primitive subpopulation in rhabdomyosarcoma cell lines that are relatively chemoresistant but sensitive to mutant HSV
    • Pressey JG, Haas MC, Pressey CS, Kelly VM, Parker JN, Gillespie GY et al. CD133 marks a myogenically primitive subpopulation in rhabdomyosarcoma cell lines that are relatively chemoresistant but sensitive to mutant HSV. Pediatr Blood Cancer 2013; 60: 45-52.
    • (2013) Pediatr Blood Cancer , vol.60 , pp. 45-52
    • Pressey, J.G.1    Haas, M.C.2    Pressey, C.S.3    Kelly, V.M.4    Parker, J.N.5    Gillespie, G.Y.6
  • 13
    • 77958001733 scopus 로고    scopus 로고
    • Ectopic matrix metalloproteinase-9 expression in human brain tumor cells enhances oncolytic HSV vector infection
    • Hong CS, Fellows W, Niranjan A, Alber S, Watkins S, Cohen JB et al. Ectopic matrix metalloproteinase-9 expression in human brain tumor cells enhances oncolytic HSV vector infection. Gene Ther 2010; 17: 1200-1205.
    • (2010) Gene Ther , vol.17 , pp. 1200-1205
    • Hong, C.S.1    Fellows, W.2    Niranjan, A.3    Alber, S.4    Watkins, S.5    Cohen, J.B.6
  • 14
    • 79955634782 scopus 로고    scopus 로고
    • Glioma stem cells targeted by oncolytic virus carrying endostatin-angiostatin fusion gene and the expression of its exogenous gene in vitro
    • Zhu G, Su W, Jin G, Xu F, Hao S, Guan F et al. Glioma stem cells targeted by oncolytic virus carrying endostatin-angiostatin fusion gene and the expression of its exogenous gene in vitro. Brain Res 2011; 1390: 59-69.
    • (2011) Brain Res , vol.1390 , pp. 59-69
    • Zhu, G.1    Su, W.2    Jin, G.3    Xu, F.4    Hao, S.5    Guan, F.6
  • 15
    • 79952719169 scopus 로고    scopus 로고
    • Chon-droitinase ABC I-mediated enhancement of oncolytic virus spread and antitumor efficacy
    • Dmitrieva N, Yu L, Viapiano M, Cripe TP, Chiocca EA, Glorioso JC et al. Chon-droitinase ABC I-mediated enhancement of oncolytic virus spread and antitumor efficacy. Clin Cancer Res 2011; 17: 1362-1372.
    • (2011) Clin Cancer Res , vol.17 , pp. 1362-1372
    • Dmitrieva, N.1    Yu, L.2    Viapiano, M.3    Cripe, T.P.4    Chiocca, E.A.5    Glorioso, J.C.6
  • 16
    • 79957881687 scopus 로고    scopus 로고
    • A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells
    • Kanai R, Wakimoto H, Martuza RL, Rabkin SD. A novel oncolytic herpes simplex virus that synergizes with phosphoinositide 3-kinase/Akt pathway inhibitors to target glioblastoma stem cells. Clin Cancer Res 2011; 17: 3686-3696.
    • (2011) Clin Cancer Res , vol.17 , pp. 3686-3696
    • Kanai, R.1    Wakimoto, H.2    Martuza, R.L.3    Rabkin, S.D.4
  • 17
    • 84869868723 scopus 로고    scopus 로고
    • Doxorubicin-enriched ALDH(br) mouse breast cancer stem cells are treatable to oncolytic herpes simplex virus type 1
    • Zhuang X, Zhang W, Chen Y, Han X, Li J, Zhang Y et al. Doxorubicin-enriched, ALDH(br) mouse breast cancer stem cells are treatable to oncolytic herpes simplex virus type 1. BMC Cancer 2012; 12: 549.
    • (2012) BMC Cancer , vol.12 , pp. 549
    • Zhuang, X.1    Zhang, W.2    Chen, Y.3    Han, X.4    Li, J.5    Zhang, Y.6
  • 18
    • 77949423196 scopus 로고    scopus 로고
    • The HSV-2 mutant DeltaPK induces melanoma oncolysis through nonredundant death programs and associated with autophagy and pyroptosis proteins
    • Colunga AG, Laing JM, Aurelian L. The HSV-2 mutant DeltaPK induces melanoma oncolysis through nonredundant death programs and associated with autophagy and pyroptosis proteins. Gene Ther 2010; 17: 315-327.
    • (2010) Gene Ther , vol.17 , pp. 315-327
    • Colunga, A.G.1    Laing, J.M.2    Aurelian, L.3
  • 19
    • 33745075558 scopus 로고    scopus 로고
    • Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases
    • Smalley KS, Haass NK, Brafford PA, Lioni M, Flaherty KT, Herlyn M. Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases. Mol Cancer Ther 2006; 5: 1136-1144.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1136-1144
    • Smalley, K.S.1    Haass, N.K.2    Brafford, P.A.3    Lioni, M.4    Flaherty, K.T.5    Herlyn, M.6
  • 20
    • 45549094086 scopus 로고    scopus 로고
    • Cancer cell death enhances the penetration and efficacy of oncolytic herpes simplex virus in tumors
    • Nagano S, Perentes JY, Jain RK, Boucher Y. Cancer cell death enhances the penetration and efficacy of oncolytic herpes simplex virus in tumors. Cancer Res 2008; 68: 3795-3802.
    • (2008) Cancer Res , vol.68 , pp. 3795-3802
    • Nagano, S.1    Perentes, J.Y.2    Jain, R.K.3    Boucher, Y.4
  • 21
    • 0031684594 scopus 로고    scopus 로고
    • The PK domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for immediate-early gene expression and virus growth
    • Smith CC, Peng T, Kulka M, Aurelian L. The PK domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) is required for immediate-early gene expression and virus growth. J Virol 1998; 72: 9131-9141.
    • (1998) J Virol , vol.72 , pp. 9131-9141
    • Smith, C.C.1    Peng, T.2    Kulka, M.3    Aurelian, L.4
  • 22
    • 0033766284 scopus 로고    scopus 로고
    • Ras-GAP binding and phosphorylation by herpes simplex virus type 2 RR1 PK (ICP10) and activation of the Ras/MEK/MAPK mitogenic pathway are required for timely onset of virus growth
    • Smith CC, Nelson J, Aurelian L, Gober M, Goswami BB. Ras-GAP binding and phosphorylation by herpes simplex virus type 2 RR1 PK (ICP10) and activation of the Ras/MEK/MAPK mitogenic pathway are required for timely onset of virus growth. J Virol 2000; 74: 10417-10429.
    • (2000) J Virol , vol.74 , pp. 10417-10429
    • Smith, C.C.1    Nelson, J.2    Aurelian, L.3    Gober, M.4    Goswami, B.B.5
  • 23
    • 33645889324 scopus 로고    scopus 로고
    • Intranasal administration of the growth-compromised HSV-2 vector DeltaRR prevents kainate-induced seizures and neuronal loss in rats and mice
    • Laing JM, Gober MD, Golembewski EK, Thompson SM, Gyure KA, Yarowsky PJ et al. Intranasal administration of the growth-compromised HSV-2 vector DeltaRR prevents kainate-induced seizures and neuronal loss in rats and mice. Mol Ther 2006; 13: 870-881.
    • (2006) Mol Ther , vol.13 , pp. 870-881
    • Laing, J.M.1    Gober, M.D.2    Golembewski, E.K.3    Thompson, S.M.4    Gyure, K.A.5    Yarowsky, P.J.6
  • 24
    • 33846520504 scopus 로고    scopus 로고
    • The HSV-2 protein ICP10PK prevents neuronal apoptosis and loss of function in an in vivo model of neurodegeneration associated with glutamate excitotoxicity
    • Golembewski EK, Wales SQ, Aurelian L, Yarowsky PJ. The HSV-2 protein ICP10PK prevents neuronal apoptosis and loss of function in an in vivo model of neurodegeneration associated with glutamate excitotoxicity. Exp Neurol 2007; 203: 381-393.
    • (2007) Exp Neurol , vol.203 , pp. 381-393
    • Golembewski, E.K.1    Wales, S.Q.2    Aurelian, L.3    Yarowsky, P.J.4
  • 25
    • 2442676718 scopus 로고    scopus 로고
    • Herpes simplex virus type 2 vaccines: New ground for optimism?
    • Aurelian L. Herpes simplex virus type 2 vaccines: new ground for optimism? Clin Diagn Lab Immunol 2004; 11: 437-445.
    • (2004) Clin Diagn Lab Immunol , vol.11 , pp. 437-445
    • Aurelian, L.1
  • 26
    • 84862014301 scopus 로고    scopus 로고
    • Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment
    • Rausch V, Liu L, Apel A, Rettig T, Gladkich J, Labsch S et al. Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment. J Pathol 2012; 227: 325-335.
    • (2012) J Pathol , vol.227 , pp. 325-335
    • Rausch, V.1    Liu, L.2    Apel, A.3    Rettig, T.4    Gladkich, J.5    Labsch, S.6
  • 27
    • 84855722559 scopus 로고    scopus 로고
    • Multicellular tumor spheroid model to evaluate spatio-temporal dynamics effect of chemotherapeutics: Application to the gemcitabine/CHK1 inhibitor combination in pancreatic cancer
    • Dufau I, Frongia C, Sicard F, Dedieu L, Cordelier P, Ausseil F et al. Multicellular tumor spheroid model to evaluate spatio-temporal dynamics effect of chemotherapeutics: application to the gemcitabine/CHK1 inhibitor combination in pancreatic cancer. BMC Cancer 2012; 12: 15.
    • (2012) BMC Cancer , vol.12 , pp. 15
    • Dufau, I.1    Frongia, C.2    Sicard, F.3    Dedieu, L.4    Cordelier, P.5    Ausseil, F.6
  • 28
    • 84876821077 scopus 로고    scopus 로고
    • Colon cancer cells adopt an invasive phenotype without mesenchymal transition in 3-D but not 2-D culture upon combined stimulation with EGF and crypt growth factors
    • Ludwig K, Tse ES, Wang JY. Colon cancer cells adopt an invasive phenotype without mesenchymal transition in 3-D but not 2-D culture upon combined stimulation with EGF and crypt growth factors. BMC Cancer 2013; 13: 221.
    • (2013) BMC Cancer , vol.13 , pp. 221
    • Ludwig, K.1    Tse, E.S.2    Wang, J.Y.3
  • 29
    • 84874793023 scopus 로고    scopus 로고
    • Growth of confined cancer spheroids: A combined experimental and mathematical modelling approach
    • Loessner D, Flegg JA, Byrne HM, Clements JA, Hutmacher DW. Growth of confined cancer spheroids: a combined experimental and mathematical modelling approach. Integr Biol (Camb) 2013; 5: 597-605.
    • (2013) Integr Biol (Camb) , vol.5 , pp. 597-605
    • Loessner, D.1    Flegg, J.A.2    Byrne, H.M.3    Clements, J.A.4    Hutmacher, D.W.5
  • 31
    • 73149110562 scopus 로고    scopus 로고
    • Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
    • Pece S, Tosoni D, Confalonieri S, Mazzarol G, Vecchi M, Ronzoni S et al. Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell 2010; 140: 62-73.
    • (2010) Cell , vol.140 , pp. 62-73
    • Pece, S.1    Tosoni, D.2    Confalonieri, S.3    Mazzarol, G.4    Vecchi, M.5    Ronzoni, S.6
  • 32
    • 77953614967 scopus 로고    scopus 로고
    • Heterogeneous phenotype of human melanoma cells with in vitro and in vivo features of tumor-initiating cells
    • Perego M, Tortoreto M, Tragni G, Mariani L, Deho P, Carbone A et al. Heterogeneous phenotype of human melanoma cells with in vitro and in vivo features of tumor-initiating cells. J Invest Dermatol 2010; 130: 1877-1886.
    • (2010) J Invest Dermatol , vol.130 , pp. 1877-1886
    • Perego, M.1    Tortoreto, M.2    Tragni, G.3    Mariani, L.4    Deho, P.5    Carbone, A.6
  • 34
    • 77949654118 scopus 로고    scopus 로고
    • Identification of virus resistant tumor cell subpopulations in three-dimensional uveal melanoma cultures
    • Valyi-Nagy K, Dosa S, Kovacs SK, Bacsa S, Voros A, Shukla D et al. Identification of virus resistant tumor cell subpopulations in three-dimensional uveal melanoma cultures. Cancer Gene Ther 2010; 17: 223-234.
    • (2010) Cancer Gene Ther , vol.17 , pp. 223-234
    • Valyi-Nagy, K.1    Dosa, S.2    Kovacs, S.K.3    Bacsa, S.4    Voros, A.5    Shukla, D.6
  • 35
    • 0036145517 scopus 로고    scopus 로고
    • The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway
    • Perkins D, Pereira EF, Gober M, Yarowsky PJ, Aurelian L. The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway. J Virol 2002; 76: 1435-1439.
    • (2002) J Virol , vol.76 , pp. 1435-1439
    • Perkins, D.1    Pereira, E.F.2    Gober, M.3    Yarowsky, P.J.4    Aurelian, L.5
  • 36
    • 79956014819 scopus 로고    scopus 로고
    • Induction of lysosomal dilation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells
    • Yoon YH, Cho KS, Hwang JJ, Lee SJ, Choi JA, Koh JY. Induction of lysosomal dilation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells. Invest Opthalmol Vis Sci 2010; 51: 6030-6037.
    • (2010) Invest Opthalmol Vis Sci , vol.51 , pp. 6030-6037
    • Yoon, Y.H.1    Cho, K.S.2    Hwang, J.J.3    Lee, S.J.4    Choi, J.A.5    Koh, J.Y.6
  • 38
    • 77955708390 scopus 로고    scopus 로고
    • Overview of macroautophagy regulation in mammalian cells
    • Mehrpour M, Esclatine A, Beau I, Codogno P. Overview of macroautophagy regulation in mammalian cells. Cell Res 2010; 20: 748-762.
    • (2010) Cell Res , vol.20 , pp. 748-762
    • Mehrpour, M.1    Esclatine, A.2    Beau, I.3    Codogno, P.4
  • 39
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell 2010; 140: 313-326.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 40
    • 84883114523 scopus 로고    scopus 로고
    • Overexpression of Atg5 in mice activates autophagy and extends lifespan
    • Pyo JO, Yoo SM, Ahn HH, Nah J, Hong SH, Kam TI et al. Overexpression of Atg5 in mice activates autophagy and extends lifespan. Nat Commun 2013; 4: 2300.
    • (2013) Nat Commun , vol.4 , pp. 2300
    • Pyo, J.O.1    Yoo, S.M.2    Ahn, H.H.3    Nah, J.4    Hong, S.H.5    Kam, T.I.6
  • 41
    • 84869495080 scopus 로고    scopus 로고
    • Ichimura Y p62/SQSTM1/A170: Physiology and pathology
    • Komatsu M, Kageyama S, Ichimura Y. p62/SQSTM1/A170: physiology and pathology. Pharmacol Res 2012; 66: 457-462.
    • (2012) Pharmacol Res , vol.66 , pp. 457-462
    • Komatsu, M.1    Kageyama, S.2
  • 42
    • 84861939463 scopus 로고    scopus 로고
    • Diaz-Meco MT p62: A versatile multitasker takes on cancer
    • Moscat J, Diaz-Meco MT p62: a versatile multitasker takes on cancer. Trends Biochem Sci 2012; 37: 230-236.
    • (2012) Trends Biochem Sci , vol.37 , pp. 230-236
    • Moscat, J.1
  • 44
    • 84862811895 scopus 로고    scopus 로고
    • Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adeno-carcinoma
    • Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S, Sugawara S et al. Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adeno-carcinoma. Cancer Sci 2012; 103: 760-766.
    • (2012) Cancer Sci , vol.103 , pp. 760-766
    • Inoue, D.1    Suzuki, T.2    Mitsuishi, Y.3    Miki, Y.4    Suzuki, S.5    Sugawara, S.6
  • 45
    • 34249789880 scopus 로고    scopus 로고
    • The ubiquitin-binding protein p62 is expressed in breast cancers showing features of aggressive disease
    • Rolland P, Madjd Z, Durrant L, Ellis IO, Layfield R, Spendlove I. The ubiquitin-binding protein p62 is expressed in breast cancers showing features of aggressive disease. Endocr Relat Cancer 2007; 14: 73-80.
    • (2007) Endocr Relat Cancer , vol.14 , pp. 73-80
    • Rolland, P.1    Madjd, Z.2    Durrant, L.3    Ellis, I.O.4    Layfield, R.5    Spendlove, I.6
  • 47
    • 77954238710 scopus 로고    scopus 로고
    • Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
    • Boiko AD, Razorenova OV, van de Rijn M, Swetter SM, Johnson DL, Ly DP et al. Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature 2010; 466: 133-137.
    • (2010) Nature , vol.466 , pp. 133-137
    • Boiko, A.D.1    Razorenova, O.V.2    Van De Rijn, M.3    Swetter, S.M.4    Johnson, D.L.5    Ly, D.P.6
  • 48
    • 84862286978 scopus 로고    scopus 로고
    • Significance of CD44 and CD24 as cancer stem cell markers: An enduring ambiguity
    • Jaggupilli A, Elkord E. Significance of CD44 and CD24 as cancer stem cell markers: an enduring ambiguity. Clin Dev Immunol 2012; 2012: 708036.
    • (2012) Clin Dev Immunol , vol.2012 , pp. 708036
    • Jaggupilli, A.1    Elkord, E.2
  • 50
    • 38049187003 scopus 로고    scopus 로고
    • Human papillomavirus E7 requires the protease calpain to degrade the retinoblastoma protein
    • Darnell GA, Schroder WA, Antalis TM, Lambley E, Major L, Gardner J et al. Human papillomavirus E7 requires the protease calpain to degrade the retinoblastoma protein. J Biol Chem 2007; 282: 37492-37500.
    • (2007) J Biol Chem , vol.282 , pp. 37492-37500
    • Darnell, G.A.1    Schroder, W.A.2    Antalis, T.M.3    Lambley, E.4    Major, L.5    Gardner, J.6
  • 52
    • 80054716821 scopus 로고    scopus 로고
    • The role of the 3D environment in hypoxia-induced drug and apoptosis resistance
    • Kim JW, Ho WJ, Wu BM. The role of the 3D environment in hypoxia-induced drug and apoptosis resistance. Anticancer Res 2011; 31: 3237-3245.
    • (2011) Anticancer Res , vol.31 , pp. 3237-3245
    • Kim, J.W.1    Ho, W.J.2    Wu, B.M.3
  • 53
    • 84877584521 scopus 로고    scopus 로고
    • Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells
    • Gong C, Bauvy C, Tonelli G, Yue W, Deloménie C, Nicolas V et al. Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells. Oncogene 2012; 32: 2261-2272.
    • (2012) Oncogene , vol.32 , pp. 2261-2272
    • Gong, C.1    Bauvy, C.2    Tonelli, G.3    Yue, W.4    Deloménie, C.5    Nicolas, V.6
  • 54
    • 84864886861 scopus 로고    scopus 로고
    • Autophagic cell death exists
    • Clarke PG, Puyal J. Autophagic cell death exists. Autophagy 2012; 8: 867-869.
    • (2012) Autophagy , vol.8 , pp. 867-869
    • Clarke, P.G.1    Puyal, J.2
  • 55
    • 79957883170 scopus 로고    scopus 로고
    • The multiple roles of autophagy in cancer
    • Rosenfeldt MT, Ryan KM. The multiple roles of autophagy in cancer. Carcinogenesis 2011; 32: 955-963.
    • (2011) Carcinogenesis , vol.32 , pp. 955-963
    • Rosenfeldt, M.T.1    Ryan, K.M.2
  • 56
    • 84884812963 scopus 로고    scopus 로고
    • Targeting autophagy as a potential therapeutic approach for melanoma therapy
    • Liu H, He Z, Simon HU. Targeting autophagy as a potential therapeutic approach for melanoma therapy. Semin Cancer Biol 2013; 23: 352-360.
    • (2013) Semin Cancer Biol , vol.23 , pp. 352-360
    • Liu, H.1    He, Z.2    Simon, H.U.3
  • 57
    • 84884417107 scopus 로고    scopus 로고
    • Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain-mediated PUMA degradation
    • Lakhter AJ, Sahu RP, Sun Y, Kaufmann WK, Androphy EJ, Travers JB et al. Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain-mediated PUMA degradation. J Invest Dermatol 2013; 133: 2247-2254.
    • (2013) J Invest Dermatol , vol.133 , pp. 2247-2254
    • Lakhter, A.J.1    Sahu, R.P.2    Sun, Y.3    Kaufmann, W.K.4    Androphy, E.J.5    Travers, J.B.6
  • 59
    • 0021052718 scopus 로고
    • Immortalization and neoplastic transformation of normal diploid cells by defined cloned DNA fragments of herpes simplex virus type 2
    • Jariwalla RJ, Aurelian L, Ts'o PO. Immortalization and neoplastic transformation of normal diploid cells by defined cloned DNA fragments of herpes simplex virus type 2. Proc Natl Acad Sci USA 1983; 19: 5902-5906.
    • (1983) Proc Natl Acad Sci USA , vol.19 , pp. 5902-5906
    • Jariwalla, R.J.1    Aurelian, L.2    Ts'O, P.O.3
  • 60
    • 20544432868 scopus 로고    scopus 로고
    • + cells in the peripheral blood transport herpes simplex virus DNA fragments to the skin of patients with erythema multiforme (HAEM)
    • + cells in the peripheral blood transport herpes simplex virus DNA fragments to the skin of patients with erythema multiforme (HAEM). J Invest Dermatol 2005; 124: 1215-1224.
    • (2005) J Invest Dermatol , vol.124 , pp. 1215-1224
    • Ono, F.1    Sharma, B.K.2    Smith, C.C.3    Burnett, J.W.4    Aurelian, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.