Impact of preoperative anemia on relapse and survival in breast cancer patients

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Zhang, Ying Jun ^a   Chen, Yu Yang ^b   Chen, Dong Tai ^a   Jiang, Yu ^a   Huang, Wan ^a   Ouyang, Han Dong ^a   Xing, Wei ^a   Zeng, Mu Sheng ^a   Xie, Xiao Ming ^a   Zeng, Weian ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b SUN YAT SEN MEMORIAL HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

Author keywords

Breast cancer; Hypoxia; Preoperative anemia; Relapse; Survival

Indexed keywords

HEMOGLOBIN;

ADULT; ANEMIA; ARTICLE; BREAST CANCER; CANCER PATIENT; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CHINA; DISEASE ASSOCIATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; METASTASIS FREE SURVIVAL; OVERALL SURVIVAL; PREOPERATIVE PERIOD; RECURRENCE FREE SURVIVAL; RETROSPECTIVE STUDY; AGED; BREAST NEOPLASMS; CANCER GRADING; COMPLICATION; METASTASIS; MIDDLE AGED; MORTALITY; PATHOLOGY; PREVALENCE; PROGNOSIS; RISK FACTOR; TREATMENT OUTCOME; TUMOR RECURRENCE;

ADULT; AGED; ANEMIA; BREAST NEOPLASMS; FEMALE; HUMANS; MIDDLE AGED; MORTALITY; NEOPLASM GRADING; NEOPLASM METASTASIS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PREOPERATIVE PERIOD; PREVALENCE; PROGNOSIS; RISK FACTORS; TREATMENT OUTCOME;

EID: 84965092069     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-844     Document Type: Article

References (40)

1. Knight K, Wade S, Balducci L: Prevalence and outcomes of anemia in cancer: a systematic review of the literature. Am J Med 2004, 116(Suppl 7A):11S-26S.
2. Hu K, Harrison LB: Impact of anemia in patients with head and neck cancer treated with radiation therapy. Curr Treat Options Oncol 2005, 6(1):31-45.
3. Choi YS, Yi CM, Sin JI, Ye GW, Shin IH, Lee TS: Impact of hemoglobin on survival of cervical carcinoma patients treated with concurrent chemoradiotherapy is dependent on lymph node metastasis findings by magnetic resonance imaging. Int J Gynecol Cancer 2006, 16(5):1846-1854.
4. Grogan M, Thomas GM, Melamed I, Wong FL, Pearcey RG, Joseph PK, Portelance L, Crook J, Jones KD: The importance of hemoglobin levels during radiotherapy for carcinoma of the cervix. Cancer 1999, 86(8):1528-1536.
5. Dunphy EP, Petersen IA, Cox RS, Bagshaw MA: The influence of initial hemoglobin and blood pressure levels on results of radiation therapy for carcinoma of the prostate. Int J Radiat Oncol Biol Phys 1989, 16(5):1173-1178.
6. Caro JJ, Salas M, Ward A, Goss G: Anemia as an independent prognostic factor for survival in patients with cancer: a systemic, quantitative review. Cancer 2001, 91(12):2214-2221.
7. Musallam KM, Tamim HM, Richards T, Spahn DR, Rosendaal FR, Habbal A, Khreiss M, Dahdaleh FS, Khavandi K, Sfeir PM, Soweid A, Hoballah JJ, Taher AT, Jamali FR: Preoperative anaemia and postoperative outcomes in non-cardiac surgery: a retrospective cohort study. Lancet 2011, 378(9800):1396-1407.
8. Soerjomataram I, Louwman MW, Ribot JG, Roukema JA, Coebergh JW: An overview of prognostic factors for long-term survivors of breast cancer. Breast Cancer Res Treat 2008, 107(3):309-330.
9. Cianfrocca M, Goldstein LJ: Prognostic and predictive factors in early-stage breast cancer. Oncologist 2004, 9(6):606-616.
10. Voduc KD, Cheang MC, Tyldesley S, Gelmon K, Nielsen TO, Kennecke H: Breast cancer subtypes and the risk of local and regional relapse. J Clin Oncol 2010, 28(10):1684-1691.
11. Kandemir EG, Mayadagli A, Turken O, Yaylaci M, Ozturk A: Pre-treatment haemoglobin concentration is a prognostic factor in patients with early-stage breast cancer. J Int Med Res 2005, 33(3):319-328.
12. Boehm DU, Lebrecht A, Schmidt M, Siggelkow W, Lindner C, Litz A, Ulbrich E, Koelbl H: Prognostic impact of haemoglobin levels in breast cancer. Anticancer Res 2007, 27(2):1223-1226.
13. Singletary SE, Allred C, Ashley P, Bassett LW, Berry D, Bland KI, Borgen PI, Clark G, Edge SB, Hayes DF, Hughes LL, Hutter RV, Morrow M, Page DL, Recht A, Theriault RL, Thor A, Weaver DL, Wieand HS, Greene FL: Revision of the American Joint Committee on Cancer staging system for breast cancer. J Clin Oncol 2002, 20(17):3628-3636.
14. Cordella C, Luebbers HT, Rivelli V, Gratz KW, Kruse AL: An evaluation of the preoperative hemoglobin level as a prognostic factor for oral squamous cell carcinoma. Head Neck Oncol 2011, 3:35.
15. Gilreath JA, Stenehjem DD, Rodgers GM: Diagnosis and treatment of cancer-related anemia. Am J Hematol 2014, 89(2):203-212.
16. Wilson J, Yao GL, Raftery J, Bohlius J, Brunskill S, Sandercock J, Bayliss S, Moss P, Stanworth S, Hyde C: A systematic review and economic evaluation of epoetin alpha, epoetin beta and darbepoetin alpha in anaemia associated with cancer, especially that attributable to cancer treatment. Health Technol Assess 2007, 11(13):1-202.
17. Thompson CA, Steensma DP: Pure red cell aplasia associated with thymoma: clinical insights from a 50-year single-institution experience. Br J Haematol 2006, 135(3):405-407.
18. Dubsky P, Sevelda P, Jakesz R, Hausmaninger H, Samonigg H, Seifert M, Denison U, Mlineritsch B, Steger G, Kwasny W, Stöger H, Bartsch R, Stierer M, Taucher S, Fridrik M, Schippinger W, Greil R, Pötter R, Gnant M, Austrian Breast and Colorectal Cancer Study Group: Anemia is a significant prognostic factor in local relapse-free survival of premenopausal primary breast cancer patients receiving adjuvant cyclophosphamide/methotrexate/ 5-fluorouracil chemotherapy. Clin Cancer Res 2008, 14(7):2082-2087.
19. Peters-Engl C, Cassik P, Schmidt I, Denison U, Medl M, Pokieser W, Sevelda P: Impact of haemoglobin levels during adjuvant chemotherapy on the survival of patients with primary breast cancer. Acta Oncol 2005, 44(2):129-133.
20. Vaupel P: The role of hypoxia-induced factors in tumor progression. Oncologist 2004, 9(Suppl 5):10-17.
21. Harrison L, Blackwell K: Hypoxia and anemia: factors in decreased sensitivity to radiation therapy and chemotherapy? Oncologist 2004, 9(Suppl 5):31-40.
22. Vaupel P, Mayer A, Hockel M: Impact of hemoglobin levels on tumor oxygenation: the higher, the better? Strahlenther Onkol 2006, 182(2):63-71.
23. Vaupel P, Mayer A, Briest S, Hockel M: Hypoxia in breast cancer: role of blood flow, oxygen diffusion distances, and anemia in the development of oxygen depletion. Adv Exp Med Biol 2005, 566:333-342.
24. Vaupel P, Harrison L: Tumor hypoxia: causative factors, compensatory mechanisms, and cellular response. Oncologist 2004, 9(Suppl 5):4-9.
25. Teicher BA: Acute and chronic in vivo therapeutic resistance. Biochem Pharmacol 2009, 77(11):1665-1673.
26. Harrison LB, Chadha M, Hill RJ, Hu K, Shasha D: Impact of tumor hypoxia and anemia on radiation therapy outcomes. Oncologist 2002, 7(6):492-508.
27. Vaupel P, Thews O, Hoeckel M: Treatment resistance of solid tumors: role of hypoxia and anemia. Med Oncol 2001, 18(4):243-259.
28. Vaupel P, Mayer A, Briest S, Hockel M: Oxygenation gain factor: a novel parameter characterizing the association between hemoglobin level and the oxygenation status of breast cancers. Cancer Res 2003, 63(22):7634-7637.
29. Vaupel P, Briest S, Hockel M: Hypoxia in breast cancer: pathogenesis, characterization and biological/therapeutic implications. Wien Med Wochenschr 2002, 152(13-14):334-342.
30. Hockel M, Vaupel P: Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst 2001, 93(4):266-276.
31. Bos R, Zhong H, Hanrahan CF, Mommers EC, Semenza GL, Pinedo HM, Abeloff MD, Simons JW, van Diest PJ, van der Wall E: Levels of hypoxiainducible factor-1 alpha during breast carcinogenesis. J Natl Cancer Inst 2001, 93(4):309-314.
32. Zhou J, Schmid T, Schnitzer S, Brune B: Tumor hypoxia and cancer progression. Cancer Lett 2006, 237(1):10-21.
33. Liao D, Johnson RS: Hypoxia: a key regulator of angiogenesis in cancer. Cancer Metastasis Rev 2007, 26(2):281-290.
34. Varlotto J, Stevenson MA: Anemia, tumor hypoxemia, and the cancer patient. Int J Radiat Oncol Biol Phys 2005, 63(1):25-36.
35. Vaupel P, Mayer A: Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev 2007, 26(2):225-239.
36. Vleugel MM, Greijer AE, Shvarts A, van der Groep P, van Berkel M, Aarbodem Y, van Tinteren H, Harris AL, van Diest PJ, van der Wall E: Differential prognostic impact of hypoxia induced and diffuse HIF-1alpha expression in invasive breast cancer. J Clin Pathol 2005, 58(2):172-177.
37. Vaupel P: Prognostic potential of the pre-therapeutic tumor oxygenation status. Adv Exp Med Biol 2009, 645:241-246.
38. Rodgers GM: A perspective on the evolution of management of cancer- and chemotherapy-induced anemia. J Natl Compr Canc Netw 2012, 10(4):434-437.
39. Rodgers GR, Becker PS, Blinder M, Cella D, Chanan-Khan A, Cleeland C, Coccia PF, Djulbegovic B, Gilreath JA, Kraut EH, Matulonis UA, Millenson MM, Reinke D, Rosenthal J, Schwartz RN, Soff G, Stein RS, Vlahovic G, Weir AB 3rd: Cancer- and chemotherapy-induced anemia. J Natl Compr Canc Netw 2012, 10(5):628-653.
40. Khorana AA, Francis CW, Blumberg N, Culakova E, Refaai MA, Lyman GH: Blood transfusions, thrombosis, and mortality in hospitalized patients with cancer. Arch Intern Med 2008, 168(21):2377-2381.