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Volumn 566, Issue , 2005, Pages 333-342

Hypoxia in breast cancer: Role of blood flow, oxygen diffusion distances, and anemia in the development of oxygen depletion

Author keywords

[No Author keywords available]

Indexed keywords

ANEMIA; BLOOD FLOW; BREAST CANCER; CANCER CHEMOTHERAPY; CONFERENCE PAPER; GENE EXPRESSION; GENOMICS; GEOMETRY; HUMAN; HYPOXEMIA; IONIZING RADIATION; MICROVASCULATURE; OXYGEN CONSUMPTION; OXYGEN DIFFUSION; OXYGEN TRANSPORT; PERFUSION PRESSURE; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; PROTEOMICS; SOLID TUMOR; VASCULARIZATION;

EID: 33646887011     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/0-387-26206-7_44     Document Type: Conference Paper
Times cited : (68)

References (50)
  • 2
    • 0036021479 scopus 로고    scopus 로고
    • Hypoxia in breast cancer: Pathogenesis, characterization and biological/therapeutic implications
    • P. Vaupel, S. Briest, and M. Höckel, Hypoxia in breast cancer: Pathogenesis, characterization and biological/therapeutic implications, Wien. Med. Wschr. 152, 334-342 (2002).
    • (2002) Wien. Med. Wschr. , vol.152 , pp. 334-342
    • Vaupel, P.1    Briest, S.2    Höckel, M.3
  • 6
    • 0034307112 scopus 로고    scopus 로고
    • A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy
    • M. Nordsmark, and J. Overgaard, A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy, Radiother. Oncol. 57, 39-43 (2000).
    • (2000) Radiother. Oncol. , vol.57 , pp. 39-43
    • Nordsmark, M.1    Overgaard, J.2
  • 11
    • 0032726709 scopus 로고    scopus 로고
    • Polarographic measurements of oxygen tension in human glioma and surrounding peritumoural brain tissue
    • D. R. Collingridge, J. M. Piepmeier, S. Rockwell, and J. P. S. Knisely, Polarographic measurements of oxygen tension in human glioma and surrounding peritumoural brain tissue, Radiother. Oncol. 53, 127-131 (1999).
    • (1999) Radiother. Oncol. , vol.53 , pp. 127-131
    • Collingridge, D.R.1    Piepmeier, J.M.2    Rockwell, S.3    Knisely, J.P.S.4
  • 15
    • 0035677961 scopus 로고    scopus 로고
    • Treatment resistance of solid tumors: Role of hypoxia and anemia
    • P. Vaupel, O. Thews, and M. Höckel, Treatment resistance of solid tumors: Role of hypoxia and anemia, Med. Oncol. 18, 243-259 (2001).
    • (2001) Med. Oncol. , vol.18 , pp. 243-259
    • Vaupel, P.1    Thews, O.2    Höckel, M.3
  • 16
    • 0009821770 scopus 로고    scopus 로고
    • Tumor hypoxia and therapeutic resistance
    • edited by M. R. Nowrousian (Springer, Berlin, Heidelberg, New York)
    • P. Vaupel, and M. Höckel, Tumor hypoxia and therapeutic resistance, in: Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology, edited by M. R. Nowrousian (Springer, Berlin, Heidelberg, New York, 2002), pp. 127-146.
    • (2002) Recombinant Human Erythropoietin (RhEPO) in Clinical Oncology , pp. 127-146
    • Vaupel, P.1    Höckel, M.2
  • 17
    • 0035925098 scopus 로고    scopus 로고
    • Tumor hypoxia: Definitions and current clinical, biologic and molecular aspects
    • M. Höckel, and P. Vaupel, Tumor hypoxia: Definitions and current clinical, biologic and molecular aspects, J. Natl. Cancer Inst. 93, 266-276 (2001).
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 266-276
    • Höckel, M.1    Vaupel, P.2
  • 18
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • G. L. Semenza, Targeting HIF-1 for cancer therapy, Nat. Rev. Cancer 3, 721-732 (2003).
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 19
    • 0036216692 scopus 로고    scopus 로고
    • HIF-1 and tumor progression: Pathophysiology and therapeutics
    • G. L. Semenza, HIF-1 and tumor progression: pathophysiology and therapeutics, Trends Mol. Med. 8, S62-S67 (2002).
    • (2002) Trends Mol. Med. , vol.8
    • Semenza, G.L.1
  • 20
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • A. L. Harris, Hypoxia - a key regulatory factor in tumour growth, Nat. Rev. Cancer 2, 38-47 (2002).
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 23
    • 0038293080 scopus 로고    scopus 로고
    • Prognostic significance of tumor oxygenation in humans
    • S. M. Evans, and C. J. Koch, Prognostic significance of tumor oxygenation in humans, Cancer Letters 195, 1-16 (2003).
    • (2003) Cancer Letters , vol.195 , pp. 1-16
    • Evans, S.M.1    Koch, C.J.2
  • 24
    • 0034000338 scopus 로고    scopus 로고
    • Prognostic value of vascular endothelial growth factor in breast cancer
    • G. Gasparini, Prognostic value of vascular endothelial growth factor in breast cancer, Oncologist 5, 37-44 (2000).
    • (2000) Oncologist , vol.5 , pp. 37-44
    • Gasparini, G.1
  • 26
    • 0043123069 scopus 로고    scopus 로고
    • Carbonic anhydrase-9 expression levels and prognosis in human breast cancer: Association with treatment outcome
    • P. N. Span, J. Bussink, P. Manders, L. V. A. M. Beex, and C. G. J. Sweep, Carbonic anhydrase-9 expression levels and prognosis in human breast cancer: association with treatment outcome, Br. J. Cancer 89, 271-276 (2003).
    • (2003) Br. J. Cancer , vol.89 , pp. 271-276
    • Span, P.N.1    Bussink, J.2    Manders, P.3    Beex, L.V.A.M.4    Sweep, C.G.J.5
  • 28
    • 0037443587 scopus 로고    scopus 로고
    • Levels of hypoxia-inducible factor-1α independently predict prognosis in patients with lymph node negative breast carcinoma
    • R. Bos, P. v. d. Groep, A. E. Greijer, A. Shvarts, S. Meijer, H. M. Pinedo, G. L. Semenza, P. J. v. Diest, and E. v. d. Wall, Levels of hypoxia-inducible factor-1α independently predict prognosis in patients with lymph node negative breast carcinoma, Cancer 97, 1573-1581 (2003).
    • (2003) Cancer , vol.97 , pp. 1573-1581
    • Bos, R.1    Groep, P.V.D.2    Greijer, A.E.3    Shvarts, A.4    Meijer, S.5    Pinedo, H.M.6    Semenza, G.L.7    Diest, P.J.V.8    Wall, E.V.D.9
  • 30
    • 0029554059 scopus 로고
    • GLUT 1 expression in human breast carcinoma: Correlation with known prognostic markers
    • M. Younes, R. W. Brown, D. R. Mody, L. Fernandez, and R. Laucirica, GLUT 1 expression in human breast carcinoma: correlation with known prognostic markers, Anticancer Res. 15, 2895-2898 (1995).
    • (1995) Anticancer Res. , vol.15 , pp. 2895-2898
    • Younes, M.1    Brown, R.W.2    Mody, D.R.3    Fernandez, L.4    Laucirica, R.5
  • 31
    • 0002624330 scopus 로고    scopus 로고
    • Tumor oxygenation: Characterization and clinical implications
    • edited by J. F. Smyth, M. A. Boogaerts, and B. R.-M. Ehmer (Marcel Dekker, New York)
    • P. Vaupel, O. Thews, and M. Höckel, Tumor oxygenation: Characterization and clinical implications, in: rhErythropoietin in Cancer Supportive Treatment, edited by J. F. Smyth, M. A. Boogaerts, and B. R.-M. Ehmer (Marcel Dekker, New York, 1996), pp. 205-239.
    • (1996) RhErythropoietin in Cancer Supportive Treatment , pp. 205-239
    • Vaupel, P.1    Thews, O.2    Höckel, M.3
  • 32
    • 0024408986 scopus 로고
    • Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
    • P. Vaupel, F. Kallinowski, and P. Okunieff, Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review, Cancer Res. 49, 6449-6465 (1989).
    • (1989) Cancer Res. , vol.49 , pp. 6449-6465
    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 34
    • 33646884230 scopus 로고    scopus 로고
    • Durchblutung, oxygenierungsstatus und metabolisches mikromilieu des mammakarzinoms. Pathomechanismen, charakterisierung und biologische/ therapeutische relevanz
    • edited by M. Untch, H. Sittek, I. Bauerfeind, G. Konecny, M. Reiser, H. Hepp (Zuckschwerdt, München)
    • P. Vaupel, and M. Höckel, Durchblutung, Oxygenierungsstatus und metabolisches Mikromilieu des Mammakarzinoms. Pathomechanismen, Charakterisierung und biologische/therapeutische Relevanz, in: Diagnostik und Therapie des Mammakarzinoms - State of the Art, edited by M. Untch, H. Sittek, I. Bauerfeind, G. Konecny, M. Reiser, H. Hepp (Zuckschwerdt, München, 2002), pp. 289-307.
    • (2002) Diagnostik und Therapie des Mammakarzinoms - State of the Art , pp. 289-307
    • Vaupel, P.1    Höckel, M.2
  • 35
    • 0021504745 scopus 로고
    • Positron emission tomography in the study of human tumors
    • R. P. Beaney, Positron emission tomography in the study of human tumors, Semin. Nucl. Med. 14, 324-341 (1984).
    • (1984) Semin. Nucl. Med. , vol.14 , pp. 324-341
    • Beaney, R.P.1
  • 36
    • 0021334174 scopus 로고
    • Positron emission tomography for in-vivo measurements of regional blood flow, oxygen utilisation, and blood volume in patients with breast carcinoma
    • R. P. Beaney, A. A. Lammertsma, T. Jones, C. G. McKenzie, and K. E. Halnan, Positron emission tomography for in-vivo measurements of regional blood flow, oxygen utilisation, and blood volume in patients with breast carcinoma, Lancet 1(8369), 131-134 (1984).
    • (1984) Lancet , vol.1 , Issue.8369 , pp. 131-134
    • Beaney, R.P.1    Lammertsma, A.A.2    Jones, T.3    McKenzie, C.G.4    Halnan, K.E.5
  • 37
    • 0017135172 scopus 로고
    • A thermodynamic method for investigation of radiation induced changes in the microcirculation of human tumors
    • R. Johnson, A thermodynamic method for investigation of radiation induced changes in the microcirculation of human tumors, Int. J. Radiat. Oncol. Biol. Phys. 1, 659-670 (1976).
    • (1976) Int. J. Radiat. Oncol. Biol. Phys. , vol.1 , pp. 659-670
    • Johnson, R.1
  • 38
    • 0026560194 scopus 로고
    • Measurements of blood flow and exchanging water space in breast tumors using positron emission tomography: A rapid and noninvasive dynamic method
    • C. B. J. H. Wilson, A. A. Lammertsma, C. G. McKenzie, K. Sikora, and T. Jones, Measurements of blood flow and exchanging water space in breast tumors using positron emission tomography: A rapid and noninvasive dynamic method, Cancer Res. 52, 1592-1597 (1992).
    • (1992) Cancer Res. , vol.52 , pp. 1592-1597
    • Wilson, C.B.J.H.1    Lammertsma, A.A.2    McKenzie, C.G.3    Sikora, K.4    Jones, T.5
  • 39
    • 0028214721 scopus 로고
    • Angiogenesis as a diagnostic factor in primary breast cancer: Microvessel quantitation by stereological methods and correlation with color Doppler sonography
    • E. M. Grischke, M. Kaufmann, M. Eberlein-Gonska, T. Mattfeld, Ch. Sohn, and G. Bastert, Angiogenesis as a diagnostic factor in primary breast cancer: Microvessel quantitation by stereological methods and correlation with color Doppler sonography, Onkologie 17, 35-42 (1994).
    • (1994) Onkologie , vol.17 , pp. 35-42
    • Grischke, E.M.1    Kaufmann, M.2    Eberlein-Gonska, M.3    Mattfeld, T.4    Sohn, Ch.5    Bastert, G.6
  • 40
    • 0030803967 scopus 로고    scopus 로고
    • Vascularization, blood flow, oxygenation, tissue pH, and bioenergetic status of human breast cancer
    • P. Vaupel, Vascularization, blood flow, oxygenation, tissue pH, and bioenergetic status of human breast cancer, Adv. Exp. Med. Biol. 411, 243-254 (1997).
    • (1997) Adv. Exp. Med. Biol. , vol.411 , pp. 243-254
    • Vaupel, P.1
  • 41
    • 0034321578 scopus 로고    scopus 로고
    • Blood supply, oxygenation status and metabolic micromilieu of breast cancers: Characterization and therapeutic relevance
    • P. Vaupel, and M. Höckel, Blood supply, oxygenation status and metabolic micromilieu of breast cancers: Characterization and therapeutic relevance, Int. J. Oncol. 17, 869-879 (2000).
    • (2000) Int. J. Oncol. , vol.17 , pp. 869-879
    • Vaupel, P.1    Höckel, M.2
  • 43
    • 0032896818 scopus 로고    scopus 로고
    • Tumor flow in malignant breast tumors measured by Doppler ultrasound: An independent predictor of survival
    • C. Peters-Engl, W. Frank, S. Leodolter, and M. Medl, Tumor flow in malignant breast tumors measured by Doppler ultrasound: an independent predictor of survival, Breast Cancer Res. Treat. 54, 65-71 (1999).
    • (1999) Breast Cancer Res. Treat. , vol.54 , pp. 65-71
    • Peters-Engl, C.1    Frank, W.2    Leodolter, S.3    Medl, M.4
  • 44
    • 0025329088 scopus 로고
    • Oxygenation of human tumors
    • P. Vaupel, Oxygenation of human tumors. Strahlenther. Onkol. 166, 377-386 (1990).
    • (1990) Strahlenther. Onkol. , vol.166 , pp. 377-386
    • Vaupel, P.1
  • 45
    • 0345707572 scopus 로고    scopus 로고
    • Oxygenation gain factor: A novel parameter characterizing the association between hemoglobin level and the oxygenation status of breast cancers
    • P. Vaupel, A. Mayer, S. Briest, and M. Höckel, Oxygenation gain factor: A novel parameter characterizing the association between hemoglobin level and the oxygenation status of breast cancers, Cancer Res. 63, 7634-7637 (2003).
    • (2003) Cancer Res. , vol.63 , pp. 7634-7637
    • Vaupel, P.1    Mayer, A.2    Briest, S.3    Höckel, M.4
  • 47
    • 0345012158 scopus 로고    scopus 로고
    • 2 extraction is a key parameter determining the oxygenation status of malignant tumors and normal tissues
    • 2 extraction is a key parameter determining the oxygenation status of malignant tumors and normal tissues, Int. J. Oncol. 22, 795-798 (2003).
    • (2003) Int. J. Oncol. , vol.22 , pp. 795-798
    • Vaupel, P.1    Thews, O.2    Kelleher, D.K.3    Konerding, M.A.4
  • 48
    • 0034743861 scopus 로고    scopus 로고
    • Oxygenation status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
    • P. Vaupel, D. K. Kelleher, and M. Höckel, Oxygenation status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy, Semin. Oncol. 28, 29-35 (2001).
    • (2001) Semin. Oncol. , vol.28 , pp. 29-35
    • Vaupel, P.1    Kelleher, D.K.2    Höckel, M.3
  • 49
    • 0038172576 scopus 로고    scopus 로고
    • Out of air is not out of action
    • D. P. Bottaro, and L. A. Liotta, Out of air is not out of action, Nature 423, 593-595 (2003).
    • (2003) Nature , vol.423 , pp. 593-595
    • Bottaro, D.P.1    Liotta, L.A.2
  • 50
    • 0029775242 scopus 로고    scopus 로고
    • Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
    • M. Höckel, K. Schlenger, B. Aral, M. Mitze, U. Schäffer, and P. Vaupel, Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix, Cancer Res. 56, 4509-4515 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 4509-4515
    • Höckel, M.1    Schlenger, K.2    Aral, B.3    Mitze, M.4    Schäffer, U.5    Vaupel, P.6


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