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Volumn 228, Issue 1, 2012, Pages 30-43

Unilateral nigrostriatal 6-hydroxydopamine lesions in mice I: Motor impairments identify extent of dopamine depletion at three different lesion sites

Author keywords

6 Hydroxydopamine; Dopamine; Motor behaviour; Mouse; Parkinson's disease; Striatum

Indexed keywords

AMPHETAMINE; APOMORPHINE; DOPAMINE; OXIDOPAMINE;

EID: 83655192207     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2011.11.027     Document Type: Article
Times cited : (93)

References (52)
  • 1
    • 41149163183 scopus 로고    scopus 로고
    • Parkinson's disease: clinical features and diagnosis
    • Jankovic J. Parkinson's disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry 2008, 79:368-376.
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , pp. 368-376
    • Jankovic, J.1
  • 2
    • 26844505808 scopus 로고    scopus 로고
    • Toxin-induced models of Parkinson's disease
    • Bove J., Prou D., Perier C., Przedborski S. Toxin-induced models of Parkinson's disease. NeuroRx 2005, 2:484-494.
    • (2005) NeuroRx , vol.2 , pp. 484-494
    • Bove, J.1    Prou, D.2    Perier, C.3    Przedborski, S.4
  • 3
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: mechanisms and models
    • Dauer W., Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003, 39:889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 5
    • 0014376793 scopus 로고
    • 6-Hydroxy-dopamine induced degeneration of central monoamine neurons
    • Ungerstedt U. 6-Hydroxy-dopamine induced degeneration of central monoamine neurons. Eur J Pharmacol 1968, 5:107-110.
    • (1968) Eur J Pharmacol , vol.5 , pp. 107-110
    • Ungerstedt, U.1
  • 6
    • 0014954436 scopus 로고
    • Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system
    • Ungerstedt U., Arbuthnott G.W. Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system. Brain Res 1970, 24:485-493.
    • (1970) Brain Res , vol.24 , pp. 485-493
    • Ungerstedt, U.1    Arbuthnott, G.W.2
  • 7
    • 0035077354 scopus 로고    scopus 로고
    • Motor behavioural changes after intracerebroventricular injection of 6-hydroxydopamine in the rat: an animal model of Parkinson's disease
    • Rodriguez Diaz M., Abdala P., Barroso-Chinea P., Obeso J., Gonzalez-Hernandez T. Motor behavioural changes after intracerebroventricular injection of 6-hydroxydopamine in the rat: an animal model of Parkinson's disease. Behav Brain Res 2001, 122:79-92.
    • (2001) Behav Brain Res , vol.122 , pp. 79-92
    • Rodriguez Diaz, M.1    Abdala, P.2    Barroso-Chinea, P.3    Obeso, J.4    Gonzalez-Hernandez, T.5
  • 8
    • 0030272769 scopus 로고    scopus 로고
    • The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments
    • Schwarting R.K., Huston J.P. The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments. Prog Neurobiol 1996, 50:275-331.
    • (1996) Prog Neurobiol , vol.50 , pp. 275-331
    • Schwarting, R.K.1    Huston, J.P.2
  • 9
    • 0030928142 scopus 로고    scopus 로고
    • Behavioral and neurochemical dynamics of neurotoxic meso-striatal dopamine lesions
    • Schwarting R.K., Huston J.P. Behavioral and neurochemical dynamics of neurotoxic meso-striatal dopamine lesions. Neurotoxicology 1997, 18:689-708.
    • (1997) Neurotoxicology , vol.18 , pp. 689-708
    • Schwarting, R.K.1    Huston, J.P.2
  • 10
    • 2342459797 scopus 로고    scopus 로고
    • A model of l-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: relation to motor and cellular parameters of nigrostriatal function
    • Lundblad M., Picconi B., Lindgren H., Cenci M.A. A model of l-DOPA-induced dyskinesia in 6-hydroxydopamine lesioned mice: relation to motor and cellular parameters of nigrostriatal function. Neurobiol Dis 2004, 16:110-123.
    • (2004) Neurobiol Dis , vol.16 , pp. 110-123
    • Lundblad, M.1    Picconi, B.2    Lindgren, H.3    Cenci, M.A.4
  • 12
    • 79954630030 scopus 로고    scopus 로고
    • Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to l-DOPA in the 6-hydroxydopamine mouse model of Parkinson's disease
    • Francardo V., Recchia A., Popovic N., Andersson D., Nissbrandt H., Cenci M.A. Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to l-DOPA in the 6-hydroxydopamine mouse model of Parkinson's disease. Neurobiol Dis 2011.
    • (2011) Neurobiol Dis
    • Francardo, V.1    Recchia, A.2    Popovic, N.3    Andersson, D.4    Nissbrandt, H.5    Cenci, M.A.6
  • 13
    • 77953800114 scopus 로고    scopus 로고
    • Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease
    • Grealish S., Mattsson B., Draxler P., Bjorklund A. Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease. Eur J Neurosci 2010, 31:2266-2278.
    • (2010) Eur J Neurosci , vol.31 , pp. 2266-2278
    • Grealish, S.1    Mattsson, B.2    Draxler, P.3    Bjorklund, A.4
  • 14
    • 0035862530 scopus 로고    scopus 로고
    • The staircase test of skilled reaching in mice
    • Baird A.L., Meldrum A., Dunnett S.B. The staircase test of skilled reaching in mice. Brain Res Bull 2001, 54:243-250.
    • (2001) Brain Res Bull , vol.54 , pp. 243-250
    • Baird, A.L.1    Meldrum, A.2    Dunnett, S.B.3
  • 15
    • 0021967159 scopus 로고
    • Quantification of lesion-induced dopaminergic supersensitivity using the rotational model in the mouse
    • Mandel R.J., Randall P.K. Quantification of lesion-induced dopaminergic supersensitivity using the rotational model in the mouse. Brain Res 1985, 330:358-363.
    • (1985) Brain Res , vol.330 , pp. 358-363
    • Mandel, R.J.1    Randall, P.K.2
  • 16
    • 19444370500 scopus 로고    scopus 로고
    • Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice
    • Iancu R., Mohapel P., Brundin P., Paul G. Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice. Behav Brain Res 2005, 162:1-10.
    • (2005) Behav Brain Res , vol.162 , pp. 1-10
    • Iancu, R.1    Mohapel, P.2    Brundin, P.3    Paul, G.4
  • 17
    • 79954630030 scopus 로고    scopus 로고
    • Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to l-DOPA in the 6-hydroxydopamine mouse model of Parkinson's disease
    • Francardo V., Recchia A., Popovic N., Andersson D., Nissbrandt H., Cenci M.A. Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to l-DOPA in the 6-hydroxydopamine mouse model of Parkinson's disease. Neurobiol Dis 2011, 42:327-340.
    • (2011) Neurobiol Dis , vol.42 , pp. 327-340
    • Francardo, V.1    Recchia, A.2    Popovic, N.3    Andersson, D.4    Nissbrandt, H.5    Cenci, M.A.6
  • 18
    • 0026101797 scopus 로고
    • Staircase test: a measure of independent forelimb reaching and grasping abilities in rats
    • Montoya C.P., Campbell-Hope L.J., Pemberton K.D., The Dunnett S.B. staircase test: a measure of independent forelimb reaching and grasping abilities in rats. J Neurosci Methods 1991, 36:219-228.
    • (1991) J Neurosci Methods , vol.36 , pp. 219-228
    • Montoya, C.P.1    Campbell-Hope, L.J.2    Pemberton, K.D.3    The, D.S.B.4
  • 20
    • 28144440866 scopus 로고    scopus 로고
    • The corridor task: a simple test of lateralised response selection sensitive to unilateral dopamine deafferentation and graft-derived dopamine replacement in the striatum
    • Dowd E., Monville C., Torres E.M., Dunnett S.B. The corridor task: a simple test of lateralised response selection sensitive to unilateral dopamine deafferentation and graft-derived dopamine replacement in the striatum. Brain Res Bull 2005, 68:24-30.
    • (2005) Brain Res Bull , vol.68 , pp. 24-30
    • Dowd, E.1    Monville, C.2    Torres, E.M.3    Dunnett, S.B.4
  • 21
    • 33845430429 scopus 로고    scopus 로고
    • Use of the narrow beam test in the rat, 6-hydroxydopamine model of Parkinson's disease
    • Allbutt H.N., Henderson J.M. Use of the narrow beam test in the rat, 6-hydroxydopamine model of Parkinson's disease. J Neurosci Methods 2007, 159:195-202.
    • (2007) J Neurosci Methods , vol.159 , pp. 195-202
    • Allbutt, H.N.1    Henderson, J.M.2
  • 22
    • 80054735497 scopus 로고    scopus 로고
    • Longitudinal analysis of the behavioural phenotype in YAC128 (C57BL/6J) Huntington's disease transgenic mice
    • Brooks S., Higgs G., Janghra N., Jones L., Dunnett S.B. Longitudinal analysis of the behavioural phenotype in YAC128 (C57BL/6J) Huntington's disease transgenic mice. Brain Res Bull 2010.
    • (2010) Brain Res Bull
    • Brooks, S.1    Higgs, G.2    Janghra, N.3    Jones, L.4    Dunnett, S.B.5
  • 23
    • 0033950675 scopus 로고    scopus 로고
    • CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury
    • Schallert T., Fleming S.M., Leasure J.L., Tillerson J.L., Bland S.T. CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury. Neuropharmacology 2000, 39:777-787.
    • (2000) Neuropharmacology , vol.39 , pp. 777-787
    • Schallert, T.1    Fleming, S.M.2    Leasure, J.L.3    Tillerson, J.L.4    Bland, S.T.5
  • 24
    • 39449113020 scopus 로고    scopus 로고
    • Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and alpha-synuclein-deleted mice
    • Alvarez-Fischer D., Henze C., Strenzke C., Westrich J., Ferger B., Hoglinger G.U., et al. Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and alpha-synuclein-deleted mice. Exp Neurol 2008, 210:182-193.
    • (2008) Exp Neurol , vol.210 , pp. 182-193
    • Alvarez-Fischer, D.1    Henze, C.2    Strenzke, C.3    Westrich, J.4    Ferger, B.5    Hoglinger, G.U.6
  • 25
    • 33750957672 scopus 로고    scopus 로고
    • Comparison of incremental and accelerating protocols of the rotarod test for the assessment of motor deficits in the 6-OHDA model
    • Monville C., Torres E.M., Dunnett S.B. Comparison of incremental and accelerating protocols of the rotarod test for the assessment of motor deficits in the 6-OHDA model. J Neurosci Methods 2006, 158:219-223.
    • (2006) J Neurosci Methods , vol.158 , pp. 219-223
    • Monville, C.1    Torres, E.M.2    Dunnett, S.B.3
  • 26
    • 13844253256 scopus 로고    scopus 로고
    • Impaired acquisition of skilled behavior in rotarod task by moderate depletion of striatal dopamine in a pre-symptomatic stage model of Parkinson's disease
    • Ogura T., Ogata M., Akita H., Jitsuki S., Akiba L., Noda K., et al. Impaired acquisition of skilled behavior in rotarod task by moderate depletion of striatal dopamine in a pre-symptomatic stage model of Parkinson's disease. Neurosci Res 2005, 51:299-308.
    • (2005) Neurosci Res , vol.51 , pp. 299-308
    • Ogura, T.1    Ogata, M.2    Akita, H.3    Jitsuki, S.4    Akiba, L.5    Noda, K.6
  • 27
    • 0029064091 scopus 로고
    • Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test
    • Olsson M., Nikkhah G., Bentlage C., Bjorklund A. Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test. J Neurosci 1995, 15:3863-3875.
    • (1995) J Neurosci , vol.15 , pp. 3863-3875
    • Olsson, M.1    Nikkhah, G.2    Bentlage, C.3    Bjorklund, A.4
  • 28
    • 68549133201 scopus 로고    scopus 로고
    • Stepping test in mice: a reliable approach in determining forelimb akinesia in MPTP-induced Parkinsonism
    • Blume S.R., Cass D.K., Tseng K.Y. Stepping test in mice: a reliable approach in determining forelimb akinesia in MPTP-induced Parkinsonism. Exp Neurol 2009, 219:208-211.
    • (2009) Exp Neurol , vol.219 , pp. 208-211
    • Blume, S.R.1    Cass, D.K.2    Tseng, K.Y.3
  • 29
    • 0019938340 scopus 로고
    • An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks
    • de Medinaceli L., Freed W.J., Wyatt R.J. An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks. Exp Neurol 1982, 77:634-643.
    • (1982) Exp Neurol , vol.77 , pp. 634-643
    • de Medinaceli, L.1    Freed, W.J.2    Wyatt, R.J.3
  • 30
    • 37349085745 scopus 로고    scopus 로고
    • Moderate degeneration of nigral neurons after repeated but not after single intrastriatal injections of low doses of 6-hydroxydopamine in mice
    • Richter F., Hamann M., Richter A. Moderate degeneration of nigral neurons after repeated but not after single intrastriatal injections of low doses of 6-hydroxydopamine in mice. Brain Res 2008, 1188:148-156.
    • (2008) Brain Res , vol.1188 , pp. 148-156
    • Richter, F.1    Hamann, M.2    Richter, A.3
  • 31
    • 67649506191 scopus 로고    scopus 로고
    • Tests to assess motor phenotype in mice: a user's guide
    • Brooks S.P., Dunnett S.B. Tests to assess motor phenotype in mice: a user's guide. Nat Rev Neurosci 2009, 10:519-529.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 519-529
    • Brooks, S.P.1    Dunnett, S.B.2
  • 32
    • 3442887483 scopus 로고    scopus 로고
    • Behavioural profiles of inbred mouse strains used as transgenic backgrounds. I: motor tests
    • Brooks S.P., Pask T., Jones L., Dunnett S.B. Behavioural profiles of inbred mouse strains used as transgenic backgrounds. I: motor tests. Genes Brain Behav 2004, 3:206-215.
    • (2004) Genes Brain Behav , vol.3 , pp. 206-215
    • Brooks, S.P.1    Pask, T.2    Jones, L.3    Dunnett, S.B.4
  • 33
    • 0032540515 scopus 로고    scopus 로고
    • A lateralised grip strength test to evaluate unilateral nigrostriatal lesions in rats
    • Dunnett S.B., Torres E.M., Annett L.E. A lateralised grip strength test to evaluate unilateral nigrostriatal lesions in rats. Neurosci Lett 1998, 246:1-4.
    • (1998) Neurosci Lett , vol.246 , pp. 1-4
    • Dunnett, S.B.1    Torres, E.M.2    Annett, L.E.3
  • 34
    • 0035783971 scopus 로고    scopus 로고
    • Unilateral striatal dopamine depletion: time-dependent effects on cortical function and behavioural correlates
    • Steiner H., Kitai S.T. Unilateral striatal dopamine depletion: time-dependent effects on cortical function and behavioural correlates. Eur J Neurosci 2001, 14:1390-1404.
    • (2001) Eur J Neurosci , vol.14 , pp. 1390-1404
    • Steiner, H.1    Kitai, S.T.2
  • 35
    • 0017097617 scopus 로고
    • The relationship between striatal and mesolimbic dopamine dysfunction and the nature of circling responses following 6-hydroxydopamine and electrolytic lesions of the ascending dopamine systems of rat brain
    • Costall B., Marsden C.D., Naylor R.J., Pycock C.J. The relationship between striatal and mesolimbic dopamine dysfunction and the nature of circling responses following 6-hydroxydopamine and electrolytic lesions of the ascending dopamine systems of rat brain. Brain Res 1976, 118:87-113.
    • (1976) Brain Res , vol.118 , pp. 87-113
    • Costall, B.1    Marsden, C.D.2    Naylor, R.J.3    Pycock, C.J.4
  • 36
    • 0019294444 scopus 로고
    • Effects of preceding sensibilization by reserpine and haloperidol on toxicity of dopaminergic agonists
    • Schmidt J., Westermann K.H. Effects of preceding sensibilization by reserpine and haloperidol on toxicity of dopaminergic agonists. Arch Toxicol Suppl 1980, 4:479-481.
    • (1980) Arch Toxicol Suppl , vol.4 , pp. 479-481
    • Schmidt, J.1    Westermann, K.H.2
  • 37
    • 8144229502 scopus 로고    scopus 로고
    • Deficits in a lateralized associative learning task in dopamine-depleted rats with functional recovery by dopamine-rich transplants
    • Dowd E., Dunnett S.B. Deficits in a lateralized associative learning task in dopamine-depleted rats with functional recovery by dopamine-rich transplants. Eur J Neurosci 2004, 20:1953-1959.
    • (2004) Eur J Neurosci , vol.20 , pp. 1953-1959
    • Dowd, E.1    Dunnett, S.B.2
  • 38
    • 44049103762 scopus 로고    scopus 로고
    • Ratings of l-DOPA-induced dyskinesia in the unilateral 6-OHDA lesion model of Parkinson's disease in rats and mice
    • Chapter 9: unit 9
    • Cenci M.A., Lundblad M. Ratings of l-DOPA-induced dyskinesia in the unilateral 6-OHDA lesion model of Parkinson's disease in rats and mice. Curr Protoc Neurosci 2007, 25. Chapter 9: unit 9.
    • (2007) Curr Protoc Neurosci , pp. 25
    • Cenci, M.A.1    Lundblad, M.2
  • 39
    • 80053608158 scopus 로고    scopus 로고
    • Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: predicting l-DOPA-induced dyskinesia
    • Smith G.A., Heuer A., Dunnett S.B., Lane E.L. Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: predicting l-DOPA-induced dyskinesia. Behav Brain Res 2012, 226:281-292.
    • (2012) Behav Brain Res , vol.226 , pp. 281-292
    • Smith, G.A.1    Heuer, A.2    Dunnett, S.B.3    Lane, E.L.4
  • 40
    • 33847042324 scopus 로고    scopus 로고
    • Time-course of nigrostriatal damage, basal ganglia metabolic changes and behavioural alterations following intrastriatal injection of 6-hydroxydopamine in the rat: new clues from an old model
    • Blandini F., Levandis G., Bazzini E., Nappi G., Armentero M.T. Time-course of nigrostriatal damage, basal ganglia metabolic changes and behavioural alterations following intrastriatal injection of 6-hydroxydopamine in the rat: new clues from an old model. Eur J Neurosci 2007, 25:397-405.
    • (2007) Eur J Neurosci , vol.25 , pp. 397-405
    • Blandini, F.1    Levandis, G.2    Bazzini, E.3    Nappi, G.4    Armentero, M.T.5
  • 41
    • 0032143368 scopus 로고    scopus 로고
    • Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat
    • Kirik D., Rosenblad C., Bjorklund A. Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat. Exp Neurol 1998, 152:259-277.
    • (1998) Exp Neurol , vol.152 , pp. 259-277
    • Kirik, D.1    Rosenblad, C.2    Bjorklund, A.3
  • 42
    • 33751196130 scopus 로고    scopus 로고
    • Amphetamine induced rotation in the assessment of lesions and grafts in the unilateral rat model of Parkinson's disease
    • Torres E.M., Dunnett S.B. Amphetamine induced rotation in the assessment of lesions and grafts in the unilateral rat model of Parkinson's disease. Eur Neuropsychopharmacol 2007, 17:206-214.
    • (2007) Eur Neuropsychopharmacol , vol.17 , pp. 206-214
    • Torres, E.M.1    Dunnett, S.B.2
  • 43
    • 0021176491 scopus 로고
    • Lesion-induced DA supersensitivity in aging C57BL/6J mice
    • Randall P.K. Lesion-induced DA supersensitivity in aging C57BL/6J mice. Brain Res 1984, 308:333-336.
    • (1984) Brain Res , vol.308 , pp. 333-336
    • Randall, P.K.1
  • 44
    • 0015619930 scopus 로고
    • Turning behavior of mice with unilateral 6-hydroxydopamine lesions in the striatum: effects of apomorphine, l-DOPA, amanthadine, amphetamine and other psychomotor stimulants
    • Von Voigtlander P.F., Moore K.E. Turning behavior of mice with unilateral 6-hydroxydopamine lesions in the striatum: effects of apomorphine, l-DOPA, amanthadine, amphetamine and other psychomotor stimulants. Neuropharmacology 1973, 12:451-462.
    • (1973) Neuropharmacology , vol.12 , pp. 451-462
    • Von Voigtlander, P.F.1    Moore, K.E.2
  • 45
    • 0018894295 scopus 로고
    • Circling behavior in rats with partial, unilateral nigro-striatal lesions: effect of amphetamine, apomorphine, and DOPA
    • Hefti F., Melamed E., Sahakian B.J., Wurtman R.J. Circling behavior in rats with partial, unilateral nigro-striatal lesions: effect of amphetamine, apomorphine, and DOPA. Pharmacol Biochem Behav 1980, 12:185-188.
    • (1980) Pharmacol Biochem Behav , vol.12 , pp. 185-188
    • Hefti, F.1    Melamed, E.2    Sahakian, B.J.3    Wurtman, R.J.4
  • 46
    • 0033560924 scopus 로고    scopus 로고
    • Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation
    • Carter R.J., Lione L.A., Humby T., Mangiarini L., Mahal A., Bates G.P., et al. Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation. J Neurosci 1999, 19:3248-3257.
    • (1999) J Neurosci , vol.19 , pp. 3248-3257
    • Carter, R.J.1    Lione, L.A.2    Humby, T.3    Mangiarini, L.4    Mahal, A.5    Bates, G.P.6
  • 47
    • 0017833529 scopus 로고
    • Compulsive, abnormal walking caused by anticholinergics in akinetic, 6-hydroxydopamine-treated rats
    • Schallert T., Whishaw I.Q., Ramirez V.D., Teitelbaum P. Compulsive, abnormal walking caused by anticholinergics in akinetic, 6-hydroxydopamine-treated rats. Science 1978, 199:1461-1463.
    • (1978) Science , vol.199 , pp. 1461-1463
    • Schallert, T.1    Whishaw, I.Q.2    Ramirez, V.D.3    Teitelbaum, P.4
  • 48
    • 0027452902 scopus 로고
    • Dopamine-rich grafts in the neostriatum and/or nucleus accumbens: effects on drug-induced behaviours and skilled paw-reaching
    • Abrous D.N., Shaltot A.R., Torres E.M., Dunnett S.B. Dopamine-rich grafts in the neostriatum and/or nucleus accumbens: effects on drug-induced behaviours and skilled paw-reaching. Neuroscience 1993, 53:187-197.
    • (1993) Neuroscience , vol.53 , pp. 187-197
    • Abrous, D.N.1    Shaltot, A.R.2    Torres, E.M.3    Dunnett, S.B.4
  • 49
    • 0017757868 scopus 로고
    • Mesolimbic dopamine neurons: effects of 6-hydroxydopamine-induced destruction and receptor blockade on drug-induced rotation of rats
    • Kelly P.H., Moore K.E. Mesolimbic dopamine neurons: effects of 6-hydroxydopamine-induced destruction and receptor blockade on drug-induced rotation of rats. Psychopharmacology (Berl) 1977, 55:35-41.
    • (1977) Psychopharmacology (Berl) , vol.55 , pp. 35-41
    • Kelly, P.H.1    Moore, K.E.2
  • 50
    • 0016772178 scopus 로고
    • Unilateral 6-hydroxydopamine lesions of nigrostriatal or mesolimbic dopamine-containing terminals and the drug-induced rotation of rats
    • Kelly P.H. Unilateral 6-hydroxydopamine lesions of nigrostriatal or mesolimbic dopamine-containing terminals and the drug-induced rotation of rats. Brain Res 1975, 100:163-169.
    • (1975) Brain Res , vol.100 , pp. 163-169
    • Kelly, P.H.1
  • 51
    • 0016826092 scopus 로고
    • Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum
    • Kelly P.H., Seviour P.W., Iversen S.D. Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum. Brain Res 1975, 94:507-522.
    • (1975) Brain Res , vol.94 , pp. 507-522
    • Kelly, P.H.1    Seviour, P.W.2    Iversen, S.D.3
  • 52
    • 15744393949 scopus 로고    scopus 로고
    • Comparison of 6-hydroxydopamine-induced medial forebrain bundle and nigrostriatal terminal lesions in a lateralised nose-poking task in rats
    • Dowd E., Dunnett S.B. Comparison of 6-hydroxydopamine-induced medial forebrain bundle and nigrostriatal terminal lesions in a lateralised nose-poking task in rats. Behav Brain Res 2005, 159:153-161.
    • (2005) Behav Brain Res , vol.159 , pp. 153-161
    • Dowd, E.1    Dunnett, S.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.