Cerebellar pathology and motor deficits in the palmitoyl protein thioesterase 1-deficient mouse

Experimental Neurology

Volumn 217, Issue 1, 2009, Pages 124-135

  Macauley, Shannon L ^a   Wozniak, David F ^a   Kielar, Catherine ^b   Tan, Yun ^c   Cooper, Jonathan D ^b   Sands, Mark S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Astrocytes; Batten disease; Cerebellar mutant; GLAST; Gliosis; Glutamine synthetase; Lysosomal storage disease; Neurodegeneration; Rotarod; Silver degeneration staining

Indexed keywords

EXCITATORY AMINO ACID TRANSPORTER; GLUTAMATE AMMONIA LIGASE; PALMITOYL PROTEIN THIOESTERASE; PROTEIN S100B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL LOSS; CONTROLLED STUDY; DEMYELINATION; GLIOSIS; IMMUNOHISTOCHEMISTRY; MICROGLIA; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURKINJE CELL; ROTAROD TEST;

AGE FACTORS; ANIMALS; APOPTOSIS; ASTROCYTES; CEREBELLUM; DISEASE MODELS, ANIMAL; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2; GLIAL FIBRILLARY ACIDIC PROTEIN; IN SITU NICK-END LABELING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; MOTOR ACTIVITY; MOVEMENT DISORDERS; NERVE DEGENERATION; NERVE GROWTH FACTORS; NEURONAL CEROID-LIPOFUSCINOSES; NEURONS; ORGAN SIZE; S100 PROTEINS; STAINING AND LABELING; THIOLESTER HYDROLASES;

EID: 64549084081     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2009.01.022     Document Type: Article

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