-
1
-
-
84938292742
-
The support of human genetic evidence for approved drug indications
-
[1] Nelson, M.R., et al. The support of human genetic evidence for approved drug indications. Nat. Genet. 47:8 (2015), 856–860.
-
(2015)
Nat. Genet.
, vol.47
, Issue.8
, pp. 856-860
-
-
Nelson, M.R.1
-
2
-
-
84978268931
-
-
A Catalog of Published Genome-Wide Association Studies. Available at: . Accessed
-
[2] L. Hindorff, et al., A Catalog of Published Genome-Wide Association Studies. Available at: www.genome.gov/gwastudies. Accessed 2014.
-
(2014)
-
-
Hindorff, L.1
-
3
-
-
77955499945
-
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
-
[3] Musunuru, K., et al. From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature 466:7307 (2010), 714–719.
-
(2010)
Nature
, vol.466
, Issue.7307
, pp. 714-719
-
-
Musunuru, K.1
-
4
-
-
84895800675
-
A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding
-
[4] Huang, Q., et al. A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding. Nat. Genet. 46:2 (2014), 126–135.
-
(2014)
Nat. Genet.
, vol.46
, Issue.2
, pp. 126-135
-
-
Huang, Q.1
-
5
-
-
84868198825
-
Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression
-
[5] Cowper-Sal, l.R., et al. Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression. Nat. Genet. 44 (2012), 1191–1198.
-
(2012)
Nat. Genet.
, vol.44
, pp. 1191-1198
-
-
Cowper-Sal, L.R.1
-
6
-
-
84865790047
-
The ENCODE Project Consortium, An integrated encyclopedia of DNA elements in the human genome
-
[6] The ENCODE Project Consortium, An integrated encyclopedia of DNA elements in the human genome. Nature, 489(7414), 2012, 57–74.
-
(2012)
Nature
, vol.489
, Issue.7414
, pp. 57-74
-
-
-
7
-
-
84878682420
-
The Genotype-Tissue Expression (GTEx) project
-
[7] The Genotype-Tissue Expression (GTEx) project. Nat. Genet., 45(6), 2013, 580–585.
-
(2013)
Nat. Genet.
, vol.45
, Issue.6
, pp. 580-585
-
-
-
8
-
-
84923362619
-
Integrative analysis of 111 reference human epigenomes
-
[8] The Roadmap Epigenomics Consortium, Integrative analysis of 111 reference human epigenomes. Nature 518:7539 (2015), 317–330.
-
(2015)
Nature
, vol.518
, Issue.7539
, pp. 317-330
-
-
The Roadmap Epigenomics Consortium1
-
9
-
-
84919949716
-
-
A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping. Cell.
-
[9] S.S.P. Rao, et al., A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping. Cell. 159(7): p. 1665–1680.
-
, vol.159
, Issue.7
, pp. 1665-1680
-
-
Rao, S.S.P.1
-
10
-
-
84951567954
-
-
CTCF-mediated human 3D genome architecture reveals chromatin topology for transcription. Cell.
-
[10] Z. Tang, et al., CTCF-mediated human 3D genome architecture reveals chromatin topology for transcription. Cell. 163(7): p. 1611–1627.
-
, vol.163
, Issue.7
, pp. 1611-1627
-
-
Tang, Z.1
-
11
-
-
84940034154
-
Genome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution
-
[11] Sahlén, P., et al. Genome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution. Genome Biol., 16(1), 2015, 156.
-
(2015)
Genome Biol.
, vol.16
, Issue.1
, pp. 156
-
-
Sahlén, P.1
-
12
-
-
67651173033
-
Identification of candidate regulatory SNPs by combination of transcription-factor-binding site prediction, SNP genotyping and haploChIP
-
[12] Ameur, A., et al. Identification of candidate regulatory SNPs by combination of transcription-factor-binding site prediction, SNP genotyping and haploChIP. Nucleic Acids Res., 37, 2009.
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Ameur, A.1
-
13
-
-
76249083492
-
Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq
-
[13] Motallebipour, M., et al. Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq. Genome Biol., 10(11), 2009, R129.
-
(2009)
Genome Biol.
, vol.10
, Issue.11
, pp. R129
-
-
Motallebipour, M.1
-
14
-
-
80051489977
-
AlleleSeq: analysis of allele-specific expression and binding in a network framework
-
[14] Rozowsky, J., et al. AlleleSeq: analysis of allele-specific expression and binding in a network framework. Mol. Syst. Biol., 7, 2011, 522.
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 522
-
-
Rozowsky, J.1
-
15
-
-
45149108420
-
Mapping the Genetic Architecture of Gene Expression in Human Liver
-
e107
-
[15] Schadt, E.E., et al. Mapping the Genetic Architecture of Gene Expression in Human Liver. PLoS Biol., 6(5), 2008, e107.
-
(2008)
PLoS Biol.
, vol.6
, Issue.5
-
-
Schadt, E.E.1
-
16
-
-
84903216991
-
Nucleosome regulatory dynamics in response to TGFβ
-
[16] Enroth, S., et al. Nucleosome regulatory dynamics in response to TGFβ. Nucleic Acids Res., 2014.
-
(2014)
Nucleic Acids Res.
-
-
Enroth, S.1
-
17
-
-
84962498653
-
-
Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression. Hum. Genet.
-
[17] M. Cavalli, et al., Allele-specific transcription factor binding to common and rare variants associated with disease and gene expression. Hum. Genet., 2016: p. 1–13.
-
(2016)
, pp. 1-13
-
-
Cavalli, M.1
-
18
-
-
84859829017
-
SLiCE: a novel bacterial cell extract-based DNA cloning method
-
e55
-
[18] Zhang, Y., Werling, U., Edelmann, W., SLiCE: a novel bacterial cell extract-based DNA cloning method. Nucleic Acids Res., 40(8), 2012, e55.
-
(2012)
Nucleic Acids Res.
, vol.40
, Issue.8
-
-
Zhang, Y.1
Werling, U.2
Edelmann, W.3
-
19
-
-
84881401766
-
The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line
-
[19] Adey, A., et al. The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line. Nature 500:7461 (2013), 207–211.
-
(2013)
Nature
, vol.500
, Issue.7461
, pp. 207-211
-
-
Adey, A.1
-
20
-
-
84891697734
-
Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits
-
[20] Corradin, O., et al. Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits. Genome Res. 24 (2014), 1–13.
-
(2014)
Genome Res.
, vol.24
, pp. 1-13
-
-
Corradin, O.1
-
21
-
-
84978264901
-
Fine-mapping cellular QTLs with RASQUAL and ATAC-seq. bioRxiv
-
[21] Kumasaka, N., Knights, A., Gaffney, D., Fine-mapping cellular QTLs with RASQUAL and ATAC-seq. bioRxiv., 2015.
-
(2015)
-
-
Kumasaka, N.1
Knights, A.2
Gaffney, D.3
-
22
-
-
84961360157
-
Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels
-
[22] Cavalli, M., et al. Looking beyond GWAS: allele-specific transcription factor binding drives the association of GALNT2 to HDL-C plasma levels. Lipids Health Dis. 15:1 (2016), 1–5.
-
(2016)
Lipids Health Dis.
, vol.15
, Issue.1
, pp. 1-5
-
-
Cavalli, M.1
-
23
-
-
84951777022
-
Multiple hepatic regulatory variants at the GALNT2 GWAS locus associated with high-density lipoprotein cholesterol
-
[23] Roman, T.S., et al. Multiple hepatic regulatory variants at the GALNT2 GWAS locus associated with high-density lipoprotein cholesterol. Am. J. Hum. Genet. 97:6 (2015), 801–815.
-
(2015)
Am. J. Hum. Genet.
, vol.97
, Issue.6
, pp. 801-815
-
-
Roman, T.S.1
-
24
-
-
84868157974
-
Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection
-
e1-12
-
[24] Patin, E., et al. Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection. Gastroenterology 143 (2012), 1244–1252, e1-12.
-
(2012)
Gastroenterology
, vol.143
, pp. 1244-1252
-
-
Patin, E.1
-
25
-
-
84865712382
-
Annotation of functional variation in personal genomes using RegulomeDB
-
[25] Boyle, A.P., et al. Annotation of functional variation in personal genomes using RegulomeDB. Genome Res. 22:9 (2012), 1790–1797.
-
(2012)
Genome Res.
, vol.22
, Issue.9
, pp. 1790-1797
-
-
Boyle, A.P.1
-
26
-
-
84978272494
-
HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
-
(Nucleic Acids Research)
-
[26] Ward, L.D., Kellis, M., HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. (Nucleic Acids Research), 2011.
-
(2011)
-
-
Ward, L.D.1
Kellis, M.2
-
27
-
-
77950404192
-
Quantifying the effect of sequence variation on regulatory interactions
-
[27] Manke, T., Heinig, M., Vingron, M., Quantifying the effect of sequence variation on regulatory interactions. Hum. Mutat. 31:4 (2010), 477–483.
-
(2010)
Hum. Mutat.
, vol.31
, Issue.4
, pp. 477-483
-
-
Manke, T.1
Heinig, M.2
Vingron, M.3
-
28
-
-
25444517056
-
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
-
[28] Marinescu, V.D., Kohane, I.S., Riva, A., MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes. BMC Bioinformatics 6:1 (2005), 1–20.
-
(2005)
BMC Bioinformatics
, vol.6
, Issue.1
, pp. 1-20
-
-
Marinescu, V.D.1
Kohane, I.S.2
Riva, A.3
-
29
-
-
84870063111
-
iASeq: integrative analysis of allele-specificity of protein-DNA interactions in multiple ChIP-seq datasets
-
[29] Wei, Y., et al. iASeq: integrative analysis of allele-specificity of protein-DNA interactions in multiple ChIP-seq datasets. BMC Genomics 13:1 (2012), 1–19.
-
(2012)
BMC Genomics
, vol.13
, Issue.1
, pp. 1-19
-
-
Wei, Y.1
-
30
-
-
84898900683
-
ALEA: a toolbox for allele-specific epigenomics analysis
-
[30] Younesy, H., et al. ALEA: a toolbox for allele-specific epigenomics analysis. Bioinformatics 30:8 (2014), 1172–1174.
-
(2014)
Bioinformatics
, vol.30
, Issue.8
, pp. 1172-1174
-
-
Younesy, H.1
-
31
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
[31] Frayling, T.M., et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316:5826 (2007), 889–894.
-
(2007)
Science
, vol.316
, Issue.5826
, pp. 889-894
-
-
Frayling, T.M.1
-
32
-
-
84940830979
-
FTO obesity variant circuitry and adipocyte browning in humans
-
[32] Claussnitzer, M., et al. FTO obesity variant circuitry and adipocyte browning in humans. N. Engl. J. Med. 373:10 (2015), 895–907.
-
(2015)
N. Engl. J. Med.
, vol.373
, Issue.10
, pp. 895-907
-
-
Claussnitzer, M.1
|