A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding

Nature Genetics

Volumn 46, Issue 2, 2014, Pages 126-135

  Huang, Qilai ^a   Whitington, Thomas ^b   Gao, Ping ^a   Lindberg, Johan F ^b   Yang, Yuehong ^a   Sun, Jielin ^c   Väisänen, Marja Riitta ^d   Szulkin, Robert ^b   Annala, Matti ^e   Yan, Jian ^b   Egevad, Lars A ^f   Zhang, Kai ^a   Lin, Ruizhu ^a   Jolma, Arttu ^b,g   Nykter, Matti ^e   Manninen, Aki ^a   Wiklund, Fredrik ^b   Vaarala, Markku H ^a,d   Visakorpi, Tapio ^e   Xu, Jianfeng ^c   Taipale, Jussi ^b,g   Wei, Gong Hong ^a   more..

^a UNIVERSITY OF OULU   (Finland)

^b KAROLINSKA INSTITUTE   (Sweden)

^c FUDAN UNIVERSITY   (China)

^d OULU UNIVERSITY HOSPITAL   (Finland)

^e TAMPERE UNIVERSITY HOSPITAL   (Finland)

^f KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^g UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA;

ALLELE; ARTICLE; CANCER GROWTH; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CHROMATIN; CHROMOSOME 6Q; CONTROLLED STUDY; DNA BINDING; GENE; GENE EXPRESSION; HOXB13 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE TUMOR; RFX6 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; UPREGULATION;

BASE SEQUENCE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 6; CLONING, MOLECULAR; COHORT STUDIES; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FINLAND; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HOMEODOMAIN PROTEINS; HUMANS; MALE; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATIC NEOPLASMS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SEQUENCE ANALYSIS, DNA; SWEDEN; TRANSCRIPTION FACTORS;

EID: 84895800675     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2862     Document Type: Article

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