Hepatoprotective effect of cornus mas fruits extract on serum biomarkers in methotrexate-induced liver injury in male rats

Pharmacologyonline

Volumn 2016, Issue 1, 2016, Pages 91-98

  Saei, H ^a   Hatami, H ^a   Azarmi, M ^a   Dehghan, G ^a  

^a UNIVERSITY OF TABRIZ   (Iran)

Author keywords

Cornus mas; Hepatoprotective; Methotrexate; Rat

Indexed keywords

EID: 84964956456     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Rossi, S, ed. Australian Medicines Handbook (2013 ed.). Adelaide: The Australian Medicines Handbook Unit Trust.
2. Joint Formulary Committee. British National Formulary (BNF) (65 ed.). London, UK: Pharmaceutical Press.
3. "WHO Model List of Essential Medicines" (PDF). World Health Organization. October 2013. Retrieved 22 April 2014.
4. Widemann, B.C., Balis, F.M., Kempf-Bielack, B., Bielack, S., Pratt, C.B., Ferrari, S., Bacci, G., Craft, A.W., Adamson, P.C. High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma. Cancer 2004; 100:2222-2232.
5. Kivity, S., Zafrir, Y., Loebstein, R., Pauzner, R., Mouallem, M., Mayan, H. Clinical characteristics and risk factors for low dose methotrexate toxicity: a cohort of 28 patients. Autoimmunity Reviews 2014; 13:1109-1113.
6. Rajagopalan, P. T. Ravi; Zhang, Zhiquan; McCourt, Lynn; Dwyer, Mary; Benkovic, Stephen J.; Hammes, Gordon G. Interaction of dihydrofolate reductase with methotrexate: Ensemble and single-molecule kinetics. Proceedings of the National Academy of Sciences 2002; 99 (21, suppl): 134816.
7. Goodsell DS. The Molecular Perspective: Methotrexate. The Oncologist 4 1999; 4: 340-341.
8. Caetano, N.N., Campello, A.P., Carnieri, E.G., Kluppel, M.L., Oliveira, M.B. Effect of methotrexate (MTX) on NAD(P)+dehydrogenases of HeLa cells: malic enzyme, 2-oxoglutarateand is citrate dehydrogenases. Cell Biochemistry and Function 1997; 15: 259-264.
9. Uraz, S., Tahan, V., Aygun, C., Eren, F., Unluguzel, G., Yuksel, M., Senturk, O., Avsar, E., Haklar, G., Celikel, C., Hulagu, S., Tozun, N. Role of ursodeoxycholic acid in prevention of methotrexate-induced liver toxicity. Digestive Diseases and Sciences 2008; 53: 1071-1077.
10. Asvadi, I., Hajipour, B., Asvadi, A., Asl, N.A., Roshangar, L., Khodadadi, A. Protective effect of pentoxyfilline in renal toxicity after methotrexate administration. European Review for Medical and Pharmacological Sciences 2011; 15: 1003-1009.
11. Babiak, R.M., Campello, A.P., Carnieri, E.G., Oliveira, M.B. Methotrexate: pentose cycle and oxidative stress. Cell Biochemistry and Function 1998; 16: 283-293.
12. Shui G, Leong LP. Residue from star fruit as valuable source for functional food ingredients and antioxidant nutraceuticals. Food Chem 2006; 97(2, suppl): 277-84.
13. Celik S, Bakırcı I, Şat IG. Physicochemical and organoleptic properties of yogurt with cornelian cherry paste. Int J Food Properties 2006; 9 (3, suppl): 401-8.
14. Tural S, Koca I. Physico-chemical and antioxidant properties of cornelian cherry fruits (Cornus mas L.) grown in Turkey. Sci Hortic 2008; 116(4, suppl):362-6.
15. Vareed SK, Reddy MK, Schutzki RE, Nair MG. Anthocyanins in Cornus alternifolia, Cornus controversa, Cornus kousa and Cornus florida fruits with health benefits. Life Sci 2006; 78(7, suppl):777-84.
16. Serteser A, Kargıoğlu M, Gök V, Bağcı Y, Özcan MM, Arslan D. An-tioxidant properties of some plants growing wild in Turkey. Gra-sas Y Aceites 2009; 60(2, suppl).
17. Seeram NP, Schutzki R, Chandra A, Nair MG. Characterization, quantification, and bioactivities of anthocyanins in Cornus species. J Agric Food Chem 2002; 50(9,suppl):2519-23.
18. Koçyiğit M, Özhatay N. Wild plants used as medicinal purpose in Yalova (Northwest Turkey). Turkish J Pharm Sci 2006; 3(2, suppl):91-103.
19. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193(1, suppl):265-75.
20. Buege JA, Aust SD. Microsomal lipid peroxidation. Methods Enzymol. 1978; 52:302-10.
21. Fowler WE, Buhle EL, Aebi U. Tubular arrays of the actin-DNase I complex induced by gadolinium. Proc Natl Acad Sci U S A. 1984; 81(6, suppl):1669-73.
22. Uz, E., Oktem, F., Yilmaz, H.R., Uzar, E., Ozguner, F. The activities of purine-catabolizing enzymes and the level of nitric oxide in rat kidneys subjected to methotrexate: protective effect of caffeic acid phenethyl ester. Molecular and Cellular Biochemistry 2005; 277:165-170.
23. Jahovic, N., Cevik, H., Sehirli, A.O., Yegen, B.C., Sener, G., Melatonin prevents methotrexate-induced hepatorenal oxidative injury in rats. Journal of Pineal Research 2003; 34:282-287.
24. Amudha, G., Josephine, A., Varalakshmi, P. Role of lipoicacid in reducing the oxidative stress induced by cyclosporine A. Clinica Chimica Acta: International Journal of Clinical Chemistry 2006; 372:134-139.
25. Ozbek, E., Cekmen, M., Simsek, A., Turkoz, Y., Soylu, A., Ilbey, Y.O., Balbay, M.D. Comparison of antioxidant enzyme activityin the internal spermatic vein and brachial veins of patients with infertile varicocele. International Urology and Nephrology 2008; 40: 679-683.
26. Cetinkaya, A., Kurutas, E.B., Bulbuloglu, E., Kantarceken, B. The effects of N-acetylcysteine on methotrexate-induced oxidative renal damage in rats. Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant Association - European Renal Association 2007; 22:284-285.
27. Ozbek, E., Cekmen, M., Simsek, A., Turkoz, Y., Soylu, A., Ilbey, Y.O., Balbay, M.D. Comparison of antioxidant enzyme activity in the internal spermatic vein and brachial veins of patients with infertile varicocele. International Urology and Nephrology 2008; 40: 679-683.
28. Amudha, G., Josephine, A., Varalakshmi, P. Role of lipoicacid in reducing the oxidative stress induced by cyclosporine A. Clinica Chimica Acta: International Journal of Clinical Chemistry 2006; 372:134-139.
29. Vardi, N., Parlakpinar, H., Cetin, A., Erdogan, A., Cetin Ozturk, I. Protective effect of beta-carotene on methotrexate-induced oxidative liver damage. Toxicologic Pathology 2010; 38: 592-597.
30. Vardi, N., Parlakpinar, H., Cetin, A., Erdogan, A., Cetin Ozturk, I. Protective effect of beta-carotene on methotrexate-induced oxidative liver damage. Toxicologic Pathology 2010; 38: 592-597.
31. El-Beshbishy, H.A., Bahashwan, S.A., Aly, H.A., Fakher, H.A. Abrogation of cisplatin-induced nephrotoxicity in mice by alpha lipoic acid through ameliorating oxidative stress and enhancing gene expression of antioxidant enzymes. European Journal of Pharmacology 2011; 668: 278-284.
32. Celik, I., Cihangiroglu, M., Ilhan, N., Akpolat, N., Akbulut, H.H. Protective effects of different antioxidants and amrinone on vancomycin-induced nephrotoxicity. Basic and Clinical Pharmacology and Toxicology 2005; 97: 325-332.