The activities of purine-catabolizing enzymes and the level of nitric oxide in rat kidneys subjected to methotrexate: Protective effect of caffeic acid phenethyl ester

Molecular and Cellular Biochemistry

Volumn 277, Issue 1-2, 2005, Pages 165-170

  Uz, Efkan ^a   Öktem, Faruk ^a   Yilmaz, H Ramazan ^a   Uzar, Ertugrul ^a   Özgüner, Fehmi ^a  

^a SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Adenosine deaminase; Caffeic acid phenethyl ester; Methotrexate; Nitric oxide; Rat kidney; Xanthine oxidase

Indexed keywords

ADENOSINE DEAMINASE; CAFFEIC ACID PHENETHYL ESTER; FREE RADICAL; METHOTREXATE; NITRIC OXIDE; PURINE; XANTHINE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME ASSAY; KIDNEY INJURY; MALE; NEPHROTOXICITY; NONHUMAN; PATHOGENESIS; RAT; RENAL PROTECTION;

ADENOSINE DEAMINASE; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CAFFEIC ACIDS; FOLIC ACID ANTAGONISTS; FREE RADICAL SCAVENGERS; KIDNEY; MALE; METHOTREXATE; NITRIC OXIDE; PHENYLETHYL ALCOHOL; PURINES; RATS; RATS, WISTAR; XANTHINE OXIDASE;

EID: 24144500009     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11010-005-5875-x     Document Type: Article

References (43)

1. Widemann BC, Balis FM, Kempf-Bielack B, Bielack S, Pratt CB, Ferrari S, Bacci G, Craft AV, Adamson PC: High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma: Incidence, treatment, and outcome. Cancer 100: 2222-2232, 2004 10.1002/cncr.20255
2. Neuman MG, Cameron RG, Haber JA, Katz GG, Malkewcz IM, Shear NH: Inducers of cytochrome P450 2E1 enhance methotrexate-induced hepatotoxicity. Clin Biochem 32: 519-536, 1999 10.1016/ S0009-9120(99)00052-1
3. Kroger H, Hauschild A, Ohde M, Bache K, Voigt WP, Thefeldt W, Kruger D: Nicotinamide and methionine reduce the liver toxic effect of methotrexate. Gen Pharmacol 33: 203-206, 1999 10.1016/ S0306-3623(98)00232-8
4. Babiak RP, Campello AP, Carnieri EG, Oliveira MB: Methotrexate: pentose cycle and oxidative stress. Cell Biochem Funct 16: 283-293, 1989 10.1002/ (SICI)1099-0844(1998120)16:4<283::AID-CBF801>3.0.CO;2-E
5. Miyazono Y, Gao F, Horie T: Oxidative stress contributes to methotrexate-induced small intestinal toxicity in rats. Scand J Gastroenterol 39: 1119-1127, 2004 10.1080/00365520410003605
6. Ross D: Glutathione, free radicals and chemotherapeutic agents. Pharmacol Ther 37: 231-249, 1988 3290908
7. Goldman D: Analysis of the cytotoxic deteminants for methotrexate (NSC-740): A role for free intracellular drug. Cancer Chemother Rep 6: 51-61, 1975
8. Jahovic N, Cevik H, Sehirli AO, Yegen BC, Sener G: Melatonin prevents methotrexate-induced hepatorenal oxidative injury in rats. J Pineal Res 34: 282-287, 2003 12662351
9. Subramaniam S, Shyamala Devi CS: Vitamin E protects intestinal basolateral membrane from CMF-induced damages in rat. Indian J Physiol Pharmacol 39: 263-266, 1995 8550122
10. Capel ID, Leach D, Dorrell HM: Vitamin E retards the lipoperoxidation resulting from anticancer drug administration. Anticancer Res 3: 59-62, 1983 6830151
11. Cristalli G, Costanzi S, Lambertucci C, Lupidi G, Vittori S, Volpini R, Camaioni E: AdeFosine deaminase: functional implications and different classes of inhibitors. Med Res Rev 21: 105-128, 2001 10.1002/ 1098-1128(200103)21:2<105::AID-MED1002>3.0.CO;2-U
12. Winn HR, Rubio R, Berne RM: Brain adenosine production in the rat during 60 seconds of ischaemia. Circ Res 45: 486-492, 1979 476871
13. Beckman JS: The double-edged role of nitric oxide in brain function and superoxide-mediated injury. J Dev Physiol 15: 53-59, 1991 1678755
14. Walker LM, Walker PD, Imam SZ, Ali SF, Mayeux PR: Evidence for peroxynitrite formation in renal ischemiareperfusion injury: Studies with the inducible nitric oxide synthase inhibitor L-N(6)-(1-iminoethyl)lysine. J Pharmacol Exp Ther 295: 417-422, 2000 10992009
15. Ozyurt H, Irmak MK, Akyol O, Sogut S: Caffeic acid phenethyl ester changes the indices of oxidative stress in serum of rats with renal ischaemia - reperfusion injury. Cell Biochem Funct 19: 259-263, 2001 10.1002/cbf.923
16. Sud'ina GF, Mirzoeva OK, Pushkareva GA, Korshunova GA, Sumbatyan NV, Varfolomeev SD: Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties. FEBS Lett 329: 21-24, 1993 10.1016/ 0014-5793(93)80184-V
17. Gurel A, Armutcu F, Sahin S, Sogut S, Ozyurt H, Gulec M, Kutlu NO, Akyol O: Protective role of alpha-tocopherol and caffeic acid phenethyl ester on ischemia-reperfusion injury via nitric oxide and myeloperoxidase in rat kidneys. Clin Chim Acta 339(1-2): 33-41, 2004 10.1016/ j.cccn.2003.09.013
18. Irmak MK, Koltuksuz U, Kutlu NO, Yagmurca M, Ozyurt H, Karaman A, Akyol O: The effect of caffeic acid phenethyl ester on ischemia-reperfusion injury in comparison with alpha-tocopherol in rat kidneys. Urol Res 29(3): 190-193, 2001 10.1007/s002400100185
19. Ozen S, Akyol O, Iraz M, Sogut S, Ozugurlu F, Ozyurt H, Ersan Odaci E, Yildirim Z: Role of caffeic acid phenethyl ester, an active component of propolis, against cisplatin-induced nephrotoxicity in rats. J Appl Toxicol 24: 27-35, 2004 10.1002/jat.941
20. Yagmurca M, Erdogan H, Iraz M, Songur A, Ucar M, Fadillioglu E: Caffeic acid phenethyl ester as a protective agent against doxorubicin nephrotoxicity in rats. Clin Chim Acta 348(1-2): 27-34, 2004 10.1016/ j.cccn.2004.03.035
21. Yilmaz HR, Uz E, Yucel N, Altuntas I, Özcelik N: Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liver. J Biochem Mol Toxicol 18: 234-238, 2004 10.1002/jbt.20028
22. Ozguner F, Armagan A, Koyu A, Caliskan S, Koylu H: A novel antioxidant agent caffeic acid phenethyl ester (CAPE) prevents shock wave-induced renal tubular oxidative stress. Urol Res 2005 (in press).
23. Jahovic N, Sener G, Cevik H, Ersoy Y, Arbak S, Yegen BC: Amelioration of methotrexate-induced enteritis by melatonin in rats. Cell Biochem Funct 22(3): 169-178, 2004 10.1002/cbf.1071
24. Uz E, Sogut S, Sahin S, Var A, Ozyurt H, Gulec M, Akyol O: The protective role of caffeic acid phenethyl ester (CAPE) on testicular tissue after testicular torsion and detorsion. World J Urol 20(4): 264-270, 2002 12215859
25. Lowry OH, Rosebrough NJ, Farr AL: Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275, 1951 14907713
26. Cortas NK, Wakid NW: Determination of inorganic nitrate in serum and urine by a kinetic cadmium-reduction method. Clin Chem 36: 1440-1443, 1990 2387039
27. Prajda N, Weber G: Malignant transforDation-linked imbalance: decreased XO activity in hepatomas. FEBS Lett 59: 245-249, 1975 10.1016/ 0014-5793(75)80385-1
28. G Giusti 1974 Adenosine deaminase In: M.V. Bergmeyer (ed) Methods of Enzymatic Analysis (2nd edn.) Academic Press New York 1092-1098
29. Abelson HT, Fosburg MT, Beardsley GP, Goorin AM, Gorka C, Link M, Link D: Methotrexate induced renal impCirment: clinical studies and rescue from systemic toxicity with high-dose leucovorin and thymidine. J Clin Oncol 1: 208-216, 1983 6607976
30. Zhang JG, Zhong LF, Zhang M, Xia YX: Protection effects of procaine on oxidative stress and toxicities of renal cortical slices from rats caused by cisplatin in vitro. Arch Toxicol 66: 354-358, 1992 10.1007/ BF01973631
31. Gurer H, Ercal N: Can antioxidants be benefical in the treatment of lead poisoning? Free Radic Biol Med 29: 927-945, 2000 10.1016/ S0891-5849(00)00413-5
32. Heenen M, Laporte M, De Graef C: Methotrexate induces apoptotic cell death in human keratinocytes. Arch Dermatol Res 290: 240-245, 1988 10.1007/s004030050298
33. Tsurusawa M, Saeki K, Fujimoto T: Differential induction of apoptosis on human lymphoblastic leukemia Nalm-6 and Molt-4 cells by various antitumor drugs. Int J Hematol 66: 79-88, 1997 10.1016/ S0925-5710(97)00583-5
34. Grum CM, Ragsdale RA, Ketai LH, Simon RH: Plasma xanthine oxidase activity in patients with adult respiratory distress syndrome. J Crit Care 2: 22-26, 1987 10.1016/0883-9441(87)90116-X
35. Sogut S, Kotuk M, Yilmaz HR, Ulu R, Ozyurt H, Yildirim Z: In vivo evidence suggesting a role for purine-catabolizing enzymes in the pathogenesis of cisplatin-induced nephrotoxicity in rats and effect of erdosteine against this toxicity. Cell Biochem Funct 22(3): 157-62, 2004 10.1002/cbf.1069
36. Sogut S, Aydi n E, Elyas H, Aksoy N, Ozyurt H, Totan Y, Akyol O: The activities of serum adenosine deaminase and xanthine oxidase enzymes in Behcet's disease. Clin Chim Acta 325: 133-138, 2002 10.1016/ S0009-8981(02)00278-4
37. Pui CH, Relling MV, Lascombes F, Harrison PL, Struxiano A, Mondesir JM, Ribeiro RC, Sandlund JT, Rivera GK, Evans WE, Mahmoud HH: Urate oxidase in prevention and treatment of hyperuricemia associated with lymphoid malignancies. Leukemia 11: 1813-1816, 1997 10.1038/sj.leu.2400850
38. Jolivet J, Cowan KH, Curt GA, Clendeninn NJ, Chabner BA: The pharmacology and clinical use of methotrexate. N Engl Med 309: 1094-1104, 1983
39. Kinoshita A, Kurosawa Y, Kondoh K, Suzuki T, Manabe A, Inukai T, Sugita K, Nakazawa S: Effects of sodium in hydration solution on plasma methotrexate concentrations following high-dose methotrexate in children with acute lymphoblastic leukemia. Cancer Chemother Pharmacol 51: 256-260, 2003 12655445
40. Neuman M, Shear NH, Bellantani S, Tiribelli C: Role of cytokines in ethanol-induced cytotoxicity in vitro in HepG2 cells. Gastroenterology 115: 157-166, 1998 9649471
41. Sogut S, Zoroglu SS, Ozyurt H, Yilmaz HR, Ozugurlu F, Sivasli E, Yetkin O, Yanik M, Tutkun H, Savas HA, Tarakcioglu M, Akyol O: Changes in nitric oxide levels and antioxidant enzyme activities may have a role in the pathophysiological mechanisms involved in autism. Clin Chim Acta 331: 111-117, 2003 10.1016/S0009-8981(03)00119-0
42. Parlakpinar H, Tasdemir S, Polat A, Bay-Karabulut A, Vardi N, Ucar M, Acet A: Protective role of caffeic acid phenethyl ester (CAPE) on gentamicin-induced acute renal toxicity in rats. Toxicology 207: 169-177, 2005 10.1016/j.tox.2004.08.024
43. Wangsiripaisan A, Gengaro PE, Nemenoff RA, Ling H, Edelstein CL, Schrier RW: Effect of nitric oxide donors on renal tubular epithelial cell-matrix adhesion. Kidney Int 55: 2281-2288, 1999 10.1046/ j.1523-1755.1999.00484.x