Role of lipoic acid in reducing the oxidative stress induced by cyclosporine A

Clinica Chimica Acta

Volumn 372, Issue 1-2, 2006, Pages 134-139

  Amudha, Ganapathy ^a   Josephine, Anthony ^a   Varalakshmi, Palaninathan ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Antioxidants; Cyclosporine A; Lipid peroxidation; Lipoic acid; Nephrotoxicity

Indexed keywords

ACID PHOSPHATASE; ALKALINE PHOSPHATASE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA GLUCURONIDASE; BIOLOGICAL MARKER; CATALASE; CATHEPSIN D; CYCLOSPORIN A; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; IMMUNOSUPPRESSIVE AGENT; LACTATE DEHYDROGENASE; N ACETYL BETA GLUCOSAMINIDASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; THIOCTIC ACID;

ACID PHOSPHATASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; KIDNEY FUNCTION; KIDNEY PARENCHYMA; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID PEROXIDATION; MALE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; TISSUE LEVEL; UPREGULATION;

ANIMALS; CYCLOSPORINE; KIDNEY; LIPID PEROXIDATION; MALE; OXIDATIVE STRESS; RATS; RATS, WISTAR; THIOCTIC ACID;

RATTUS NORVEGICUS;

EID: 33747861727     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2006.03.036     Document Type: Article

References (46)

1. Kahan B.D. Cyclosporine. N Engl J Med 321 (1989) 1725-1738
2. Busauschina A., Schnuelle P., and Van der Woude F.J. Cyclosporine nephrotoxicity. Transplant Proc 36 (2004) 229S-233S
3. Farthing M.G.J., and Clark M.L. Nature of the toxicity of cyclosporine A in the rat. Biochem Pharmacol 24 (1981) 3311-3316
4. Zhong Z., Arteel G.E., Connor H.D., et al. Cyclosporine A increases hypoxia and free radical production in rat kidneys: prevention by dietary glycine. Am J Physiol 275 (1998) F595-F604
5. Lassila M., Santisteban J., Finckenberg P., et al. Vascular changes in cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on high sodium diet. J Physiol Pharmacol 52 (2001) 21-38
6. Wang C., and Salahudeen A.K. Lipid peroxidation accompanies cyclosporine nephrotoxicity: effects of vitamin E. Kidney Int 47 (1995) 927-934
7. Halliwell B., and Gutteridge J.M.C. Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem J 219 (1984) 1-14
8. Parra Cid T., Conejo Garcia J.R., Carballo Alvarez F., et al. Antioxidant nutrients protect against cyclosporine A nephrotoxicity. Toxicology 189 (2003) 99-111
9. Packer L., Witt E.H., and Tritschler H.J. Alpha-lipoic acid as a biological antioxidant. Free Radic Biol Med 19 (1995) 227-250
10. Kagan V.E., Shvedova A., Serbinova E., et al. Dihydrolipoic acid-a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals. Biochem Pharmacol 44 (1992) 1637-1649
11. Malarkodi K.P., Balachandar A.V., and Varalakshmi P. The influence of lipoic acid on adriamycin induced nephrotoxicity in rats. Mol Cell Biochem 247 (2003) 15-22
12. Sivaprasad R., Nagaraj M., and Varalakshmi P. Combined efficacies of lipoic acid and meso 2,3-dimercaptosuccinic acid against lead induced lipid peroxidation in rat liver. J Nutr Biochem 15 (2004) 18-23
13. Murugavel P., and Pari L. Attenuation of chloroquine-induced renal damage by alpha-lipoic acid: possible antioxidant mechanism. Ren Fail 26 (2004) 517-524
14. King J. The phosphohydrolases-acid and alkaline phosphatases. In: Van D. (Ed). Practical clinical enzymology (1965), Norstrand Company Ltd, London 191-208
15. King J. The dehydrogenases or oxidoreductases-lactate dehydrogenase. In: Van D. (Ed). Practical clinical enzymology (1965), Norstrand Company Ltd, London 83-93
16. Maruhn D. Rapid colorimetric assay of beta-galactosidase and N-acetyl-beta-galactosaminidase in human urine. Clin Chim Acta 73 (1976) 453-461
17. Biber J., Steiger B., Haase W., and Murer H. A higher yield preparation for kidney brush border membranes: different behaviour of lysosomal markers. Biochim Biophys Acta 647 (1981) 169-176
18. Kawai Y., and Anno K. Mucopolysaccharides degrading enzymes from the liver of the squid Ommastrephes slooni pacificus. I. Hyaluronidase. Biochim Biophys Acta 242 (1971) 428-436
19. Lowry O.H., Rosenbrough N.J., Farr A.I., and Randall R.J. Protein measurement with the folin phenol reagent. J Biol Chem 193 (1951) 265-275
20. Hogberg J., Larson R.E., Kristoferson A., and Orrenius S. NADPH-dependent reductase solubilized from microsomes by peroxidation and its activity. Biochem Biophys Res Commun 56 (1974) 836-842
21. Devasagayam T.P.A. Lipid peroxidation in rat uterus. Biochim Biophys Acta 876 (1986) 507-514
22. Marklund S., and Marklund G. Involvement of superoxide anion radical in the autooxidation of pyrrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47 (1974) 469-474
23. Sinha A.K. Colorimetric assay of catalase. Ann Biochem 47 (1972) 389-394
24. Rotruck J.T., Pope A.L., Ganther H.E., Swanson A.B., Hafeman D.G., and Hoekstra W.G. Selenium: biochemical role as a component of glutathione peroxidase. Science 179 (1973) 588-590
25. Habig W.H., Pabst M.J., and Jacob W.B. Glutathione-S-transferase. The first enzymatic step in mercapturic acid formation. J Biol Chem 249 (1979) 7130-7139
26. Beutler E. Active transport of glutathione disulfide from erythrocytes. In: Larson A., Orrenius S., Holmgren B., and Mannerwik B. (Eds). Functions of glutathione: biochemical, physiological, toxicological and clinical aspects (1983), Raven Press, New York 65
27. Staal G.E., Visser J., and Veeger C. Purification and properties of glutathione reductase of human erythrocytes. Biochim Biophys Acta 185 (1969) 39-48
28. Moron M.S., Defierre J.W., and Mannervik B. Levels of glutathione, glutathione reductase, glutathione-S-transferase activities in rat lung and liver. Biochim Biophys Acta 582 (1979) 67-78
29. Omaye S.T., Turnbull J.D., and Sauberlich H.E. Selected methods for the determination of ascorbic acid in animal cell, tissues and fluids. Methods Enzymol 62 (1979) 3-11
30. Desai I.D. Vitamin E analysis methods for animal tissues. Methods Enzymol 105 (1984) 138-147
31. In: Cheesman K.H., and Slater T.F. (Eds). Free radicals in medicine. Br Med Bull vol. 49 (3) (1993) 479-724
32. Chander V., Tirkey N., and Chopra K. Resveratrol, a polyphenolic Phytoalexin protects against cyclosporine-induced nephrotoxicity through nitric oxide dependent mechanism. Toxicology 210 (2005) 55-64
33. Whiting P.H., and Brown P.A. The relationship between enzymuria and kidney enzyme activities in experimental gentamicin nephrotoxicity. Renal Failure 18 (1996) 899-909
34. Mohamadin A.M., El-Beshbishy H.A., and El-Mahdy M.A. Green tea extract attenuates cyclosporine A-induced oxidative stress in rats. Pharmacol Res 51 (2005) 51-57
35. Cooper B., Creeth J.M., and Donald A.S. Studies of the limited degradation of mucous glycoproteins: the mechanism of the peroxide reaction. Biochem J 228 (1985) 615-626
36. Inselmann G., Hannemann J., and Baumann K. Cyclosporine A induced lipid peroxidation and influence on glucose-6-phosphatase in rat hepatic and renal microsomes. Res Commun Chem Pathol Pharmacol 68 (1990) 189-203
37. Ou P., Tritschler H.J., and Wolff S.P. Thioctic (lipoic) acid: a therapeutic metal-chelating antioxidant?. Biochem Pharmacol 50 (1995) 123-126
38. Satanarayana P.S., Singh D., and Chopra K. Quercetin, a bioflavonoid, protects against oxidative stress-related renal dysfunction by cyclosporine in rats. Methods Find Exp Clin Pharmacol 23 (2001) 175-181
39. Biewenga G.P., Vriesman M.F., Haenen G.R.M.M., and Bast A. In: Beiwanga G.P. (Ed). The identification of a new metabolite of lipoic acid in man: 3-ketolipoic acids, a pharmacochemical study (1997), Academisch Proefschrift. Vrije Universiteit, Amsterdam 137-151
40. Kirman M.N., and Gaetani G.F. Catalase: a tetrameric enzyme with 4 tightly bound molecules of NADPH. Proc Natl Acad Sci U S A 81 (1984) 4343-4347
41. Nordberg J., and Arner E.S. Reactive oxygen species, antioxidants and the mammalian thioredoxin system. Free Radic Biol Med 31 (2001) 1287-1312
42. Zhang J.G., and Lindup W.E. Tiopronin protects against the nephrotoxicity of Cisplantin in rat renal cortical slices in vitro. Toxicol Appl Pharmacol 141 (1996) 425-433
43. Han D., Handleman G., Marcocci L., et al. Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization. Biofactors 6 (1997) 321-338
44. Pick U., Haramaki N., Constantinescu A., et al. Glutathione reductase and lipoamide dehydrogenase have opposite stereospecificites for alpha-lipoic acid enantiomers. Biochem Biophys Res Commun 206 (1995) 724-730
45. Jones D.P. Redox potential of GSH/GSSG couple: assay and biological significance. Methods Enzymol 348 (2002) 93-112
46. Papas A.M. Antioxidant status, diet, nutrition and health (1998), CRC Press, New York 133-210