-
1
-
-
0036009115
-
Nf-α b at the crossroads of life and death
-
Karin, M. & Lin, A. NF-α B at the crossroads of life and death. Nat. Immunol. 3, 221-227 (2002).
-
(2002)
Nat. Immunol
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
2
-
-
80051987703
-
Crosstalk in nf-α b signaling pathways
-
Oeckinghaus, A., Hayden, M. S. & Ghosh, S. Crosstalk in NF-α B signaling pathways. Nat. Immunol. 12, 695-708 (2011).
-
(2011)
Nat. Immunol
, vol.12
, pp. 695-708
-
-
Oeckinghaus, A.1
Hayden, M.S.2
Ghosh, S.3
-
3
-
-
25844459154
-
Nf-α b: Linking inflammation and immunity to cancer development and progression
-
Karin, M. & Greten, F. R. NF-α B: linking inflammation and immunity to cancer development and progression. Nat. Rev. Immunol. 5, 749-759 (2005).
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
4
-
-
0036717195
-
Nf-α b, chemokine gene transcription and tumour growth
-
Richmond, A. NF-α B, chemokine gene transcription and tumour growth. Nat. Rev. Immunol. 2, 664-674 (2002).
-
(2002)
Nat. Rev. Immunol
, vol.2
, pp. 664-674
-
-
Richmond, A.1
-
6
-
-
73849095427
-
The nuclear signaling of nf-α b: Current knowledge, new insights, and future perspectives
-
Wan, F. & Lenardo, M. J. The nuclear signaling of NF-α B: current knowledge, new insights, and future perspectives. Cell Res. 20, 24-33 (2010).
-
(2010)
Cell Res
, vol.20
, pp. 24-33
-
-
Wan, F.1
Lenardo, M.J.2
-
7
-
-
85012048863
-
Chromatin remodeling and transcriptional control in innate immunity: Emergence of akirin2 as a novel player
-
Tartey, S. & Takeuchi, O. Chromatin remodeling and transcriptional control in innate immunity: emergence of Akirin2 as a novel player. Biomolecules. 5, 1618-1633 (2015).
-
(2015)
Biomolecules
, vol.5
, pp. 1618-1633
-
-
Tartey, S.1
Takeuchi, O.2
-
8
-
-
84859946812
-
Inhibition of nf-α b signaling as a strategy in disease therapy
-
Gilmore, T. D. & Garbati, M. R. Inhibition of NF-α B signaling as a strategy in disease therapy. Curr. Top Microbiol. Immunol. 349, 245-263 (2011).
-
(2011)
Curr. Top Microbiol. Immunol
, vol.349
, pp. 245-263
-
-
Gilmore, T.D.1
Garbati, M.R.2
-
10
-
-
79951669207
-
The immune system in atherosclerosis
-
Hansson, G. K. & Hermansson, A. The immune system in atherosclerosis. Nat. Immunol. 12, 204-212 (2011).
-
(2011)
Nat. Immunol
, vol.12
, pp. 204-212
-
-
Hansson, G.K.1
Hermansson, A.2
-
11
-
-
13044250453
-
Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity
-
Miyakawa, H., Woo, S. K., Dahl, S. C., Handler, J. S. & Kwon, H. M. Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity. Proc. Natl Acad. Sci. USA. 96, 2538-2542 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 2538-2542
-
-
Miyakawa, H.1
Woo, S.K.2
Dahl, S.C.3
Handler, J.S.4
Kwon, H.M.5
-
12
-
-
0033594887
-
Nfat5, a constitutively nuclear nfat protein that does not cooperate with fos and jun
-
Lopez-Rodriguez, C., Aramburu, J., Rakeman, A. S. & Rao, A. NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun. Proc. Natl. Acad. Sci. USA. 96, 7214-7219 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 7214-7219
-
-
Lopez-Rodriguez, C.1
Aramburu, J.2
Rakeman, A.S.3
Rao, A.4
-
13
-
-
33750503098
-
Regulation of the hypertonic stress response and other cellular functions by the rel-like transcription factor nfat5
-
Aramburu, J. et al. Regulation of the hypertonic stress response and other cellular functions by the Rel-like transcription factor NFAT5. Biochem. Pharmacol. 72, 1597-1604 (2006).
-
(2006)
Biochem. Pharmacol
, vol.72
, pp. 1597-1604
-
-
Aramburu, J.1
-
14
-
-
79954480118
-
Tonebp stimulates multiple cellular pathways for adaptation to hypertonic stress: Organic osmolyte-dependent and-independent pathways
-
Lee, S. D. et al. TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress: organic osmolyte-dependent and-independent pathways. Am. J. Physiol Renal. Physiol. 300, F707-715 (2007).
-
(2007)
Am. J. Physiol Renal. Physiol
, vol.300
, pp. F707-715
-
-
Lee, S.D.1
-
15
-
-
3242674944
-
Nfat5/tonebp mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment
-
Go, W. Y., Liu, X., Roti, M. A., Liu, F. & Ho, S. N. NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment. Proc. Natl Acad. Sci. USA. 101, 10673-10678 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 10673-10678
-
-
Go, W.Y.1
Liu, X.2
Roti, M.A.3
Liu, F.4
Ho, S.N.5
-
16
-
-
84856947469
-
Gene expression induced by toll-like receptors in macrophages requires the transcription factor nfat5
-
Buxadé, M. et al. Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5. J. Exp. Med. 209, 379-393 (2012).
-
(2012)
J. Exp. Med
, vol.209
, pp. 379-393
-
-
Buxadé, M.1
-
17
-
-
84907830962
-
The xanthine oxidase-nfat5 pathway regulates macrophage activation and tlr-induced inflammatory arthritis
-
Kim, N. H. et al. The xanthine oxidase-NFAT5 pathway regulates macrophage activation and TLR-induced inflammatory arthritis. Eur J Immunol. 44, 2721-2736 (2014).
-
(2014)
Eur J Immunol
, vol.44
, pp. 2721-2736
-
-
Kim, N.H.1
-
18
-
-
79959813471
-
Nfat5 is a critical regulator of inflammatory arthritis
-
Yoon, H. J. et al. NFAT5 is a critical regulator of inflammatory arthritis. Arthritis Rheum. 63, 1843-1852 (2011).
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1843-1852
-
-
Yoon, H.J.1
-
19
-
-
84866502277
-
Nfat5 expression in bone marrow-derived cells enhances atherosclerosis and drives macrophage migration
-
Halterman, J. A., Kwon, H. M., Leitinger, N. & Wamhoff, B. R. NFAT5 expression in bone marrow-derived cells enhances atherosclerosis and drives macrophage migration. Front. Physiol. 3, 1-7 (2012).
-
(2012)
Front. Physiol
, vol.3
, pp. 1-7
-
-
Halterman, J.A.1
Kwon, H.M.2
Leitinger, N.3
Wamhoff, B.R.4
-
20
-
-
80355146399
-
Transcriptional regulation of macrophage polarization: Enabling diversity with identity
-
Lawrence, T. & Natoli, G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat Rev Immunol. 11, 750-761 (2011).
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 750-761
-
-
Lawrence, T.1
Natoli, G.2
-
21
-
-
84926454961
-
Generation of a conditional knockout allele for the nfat5 gene in mice
-
Küper, C., Beck, F. X. & Neuhofer, W. Generation of a conditional knockout allele for the NFAT5 gene in mice. Front Physiol. 5, 507 (2015).
-
(2015)
Front Physiol
, vol.5
, pp. 507
-
-
Küper, C.1
Beck, F.X.2
Neuhofer, W.3
-
22
-
-
0033177995
-
Conditional gene targeting in macrophages and granulocytes using lysmcre mice
-
Clausen, B. E., Burkhardt, C., Reith, W., Renkawitz, R. & Förster, I. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8, 265-277 (1999).
-
(1999)
Transgenic Res
, vol.8
, pp. 265-277
-
-
Clausen, B.E.1
Burkhardt, C.2
Reith, W.3
Renkawitz, R.4
Förster, I.5
-
23
-
-
27644577000
-
Animal models of sepsis: Setting the stage
-
Buras, J. A., Holzmann, B. & Sitkovsky, M. Animal models of sepsis: setting the stage. Nat Rev Drug Discov. 4, 854-865 (2005).
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 854-865
-
-
Buras, J.A.1
Holzmann, B.2
Sitkovsky, M.3
-
24
-
-
0036294669
-
Dimerization is required for phosphorylation and DNA binding of tonebp/nfat5
-
Lee, S. D., Woo, S. K. & Kwon, H. M. Dimerization is required for phosphorylation and DNA binding of TonEBP/NFAT5. Biochem Biophys Res Commun. 294, 967-975 (2002).
-
(2002)
Biochem Biophys Res Commun
, vol.294
, pp. 967-975
-
-
Lee, S.D.1
Woo, S.K.2
Kwon, H.M.3
-
25
-
-
0348111474
-
Multiple domains of tonebp cooperate to stimulate transcription in response to hypertonicity
-
Lee, S. D., Colla, E., Sheen, M. R., Na, K. Y. & Kwon, H. M. Multiple domains of TonEBP cooperate to stimulate transcription in response to hypertonicity. J Biol Chem. 278, 47571-47577 (2003).
-
(2003)
J Biol Chem
, vol.278
, pp. 47571-47577
-
-
Lee, S.D.1
Colla, E.2
Sheen, M.R.3
Na, K.Y.4
Kwon, H.M.5
-
26
-
-
30744458869
-
Ikappab kinase alpha-mediated derepression of smrt potentiates acetylation of rela/p65 by p300
-
Hoberg, J. E., Popko, A. E., Ramsey, C. S. & Mayo, M. W. IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300. Mol Cell Biol. 26, 457-471 (2006).
-
(2006)
Mol Cell Biol
, vol.26
, pp. 457-471
-
-
Hoberg, J.E.1
Popko, A.E.2
Ramsey, C.S.3
Mayo, M.W.4
-
27
-
-
0025186678
-
Kappa b-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages
-
Shakhov, A. N. et al. Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages. J Exp Med. 171, 35-47 (1990).
-
(1990)
J Exp Med
, vol.171
, pp. 35-47
-
-
Shakhov, A.N.1
-
28
-
-
0033867980
-
A lipopolysaccharide-specific enhancer complex involving ets, elk-1, sp1, and creb binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo
-
Tsai, E. Y. et al. A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo. Mol Cell Biol. 20, 6084-6094 (2000).
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6084-6094
-
-
Tsai, E.Y.1
-
29
-
-
0024332260
-
Binding site of cerulenin in fatty acid synthetase
-
Funabashi, H. et al. Binding site of cerulenin in fatty acid synthetase. J Biochem. 105, 751-755 (1989).
-
(1989)
J Biochem
, vol.105
, pp. 751-755
-
-
Funabashi, H.1
-
30
-
-
0030914691
-
Creb-binding protein/p300 are transcriptional coactivators of p65
-
Gerritsen, M. E. et al. CREB-binding protein/p300 are transcriptional coactivators of p65. Proc. Natl Acad. Sci. USA. 94, 2927-2932 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 2927-2932
-
-
Gerritsen, M.E.1
-
31
-
-
0030614504
-
Regulation of nf-kappab by cyclin-dependent kinases associated with the p300 coactivator
-
Perkins, N. D. et al. Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science. 275, 523-527 (1997).
-
(1997)
Science
, vol.275
, pp. 523-527
-
-
Perkins, N.D.1
-
32
-
-
84927730094
-
The acetyltransferase hat1 moderates the nf-α b response by regulating the transcription factor plzf
-
Sadler, A. J. et al. The acetyltransferase HAT1 moderates the NF-α B response by regulating the transcription factor PLZF. Nat Commun. 6, 6795 (2015).
-
(2015)
Nat Commun
, vol.6
, pp. 6795
-
-
Sadler, A.J.1
-
33
-
-
0032493754
-
Transcription of the sodium/myo-inositol cotransporter gene is regulated by multiple tonicity-responsive enhancers spread over 50 kilobase pairs in the 5'-flanking region
-
Rim, J. S. et al. Transcription of the sodium/myo-inositol cotransporter gene is regulated by multiple tonicity-responsive enhancers spread over 50 kilobase pairs in the 5'-flanking region. J Biol Chem. 273, 20615-20621 (1998).
-
(1998)
J Biol Chem
, vol.273
, pp. 20615-20621
-
-
Rim, J.S.1
-
34
-
-
0031958591
-
Cis-And trans-Acting factors regulating transcription of the bgt1 gene in response to hypertonicity
-
Miyakawa, H. et al. Cis-And trans-Acting factors regulating transcription of the BGT1 gene in response to hypertonicity. Am J Physiol. 274, F753-761 (1998).
-
(1998)
Am J Physiol
, vol.274
, pp. F753-761
-
-
Miyakawa, H.1
-
35
-
-
84930674014
-
Tonebp suppresses adipogenesis and insulin sensitivity by blocking epigenetic transition of PPAR? 2
-
Lee, J. H. et al. TonEBP suppresses adipogenesis and insulin sensitivity by blocking epigenetic transition of PPAR? 2. Sci Rep. 5, 10937 (2015).
-
(2015)
Sci Rep
, vol.5
, pp. 10937
-
-
Lee, J.H.1
-
36
-
-
33746531095
-
Mechanism of action of a distal nf-kappab-dependent enhancer
-
Teferedegne, B., Green, M. R., Guo, Z. & Boss, J. M. Mechanism of action of a distal NF-kappaB-dependent enhancer. Mol Cell Biol. 26, 5759-5770 (2006).
-
(2006)
Mol Cell Biol
, vol.26
, pp. 5759-5770
-
-
Teferedegne, B.1
Green, M.R.2
Guo, Z.3
Boss, J.M.4
-
37
-
-
79952773453
-
Modulation of nf-α b signalling by microbial pathogens
-
Rahman, M. M. & McFadden, G. Modulation of NF-α B signalling by microbial pathogens. Nat Rev Microbiol. 9, 291-306 (2011).
-
(2011)
Nat Rev Microbiol
, vol.9
, pp. 291-306
-
-
Rahman, M.M.1
McFadden, G.2
-
38
-
-
77951602823
-
Nuclear receptor transrepression pathways that regulate inflammation in macrophages and t cells
-
Glass, C. K. & Saijo, K. Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells. Nat Rev Immunol. 10, 365-376 (2010).
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 365-376
-
-
Glass, C.K.1
Saijo, K.2
-
39
-
-
0035979775
-
Reversal of obesity-And diet-induced insulin resistance with salicylates or targeted disruption of ikkbeta
-
Yuan, M. et al. Reversal of obesity-And diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science. 293, 1673-1677 (2001).
-
(2001)
Science
, vol.293
, pp. 1673-1677
-
-
Yuan, M.1
-
40
-
-
84879564109
-
Salicylate (salsalate) in patients with type 2 diabetes: A randomized trial
-
Goldfine, A. B. et al. Salicylate (salsalate) in patients with type 2 diabetes: a randomized trial. Ann Intern Med. 159, 1-12 (2013).
-
(2013)
Ann Intern Med
, vol.159
, pp. 1-12
-
-
Goldfine, A.B.1
-
41
-
-
78149474133
-
Fatty acid synthase as a novel target for meningioma therapy
-
Haase, D. et al. Fatty acid synthase as a novel target for meningioma therapy. Neuro Oncol. 12, 844-854 (2010).
-
(2010)
Neuro Oncol
, vol.12
, pp. 844-854
-
-
Haase, D.1
-
42
-
-
35748937946
-
Transcriptional activator tone-binding protein in cellular protection and differentiation
-
Kim, J. A., Jeon, U. S., Kwon, M. S., Lim, S. W. & Kwon, H. M. . Transcriptional activator TonE-binding protein in cellular protection and differentiation. Methods Enzymol. 428, 253-267 (2007).
-
(2007)
Methods Enzymol.
, vol.428
, pp. 253-267
-
-
Kim, J.A.1
Jeon, U.S.2
Kwon, M.S.3
Lim, S.W.4
Kwon, H.M.5
|