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Volumn 44, Issue 9, 2014, Pages 2721-2736

The xanthine oxidase-NFAT5 pathway regulates macrophage activation and TLR-induced inflammatory arthritis

Author keywords

Inflammatory arthritis; Innate immunity; Nfat5; Reactive oxygen species; Xanthine oxidase

Indexed keywords

IL6 PROTEIN, HUMAN; INTERLEUKIN 6; NFAT5 PROTEIN, HUMAN; NFAT5 PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR; XANTHINE OXIDASE;

EID: 84907830962     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343669     Document Type: Article
Times cited : (38)

References (44)
  • 1
    • 0034907525 scopus 로고    scopus 로고
    • Bridging the NFAT and NF-κB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress
    • López-Rodríguez, C., Aramburu, J., Jin, L., Rakeman, A. S., Michino, M. and Rao, A., Bridging the NFAT and NF-κB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress. Immunity 2001. 15: 47-58.
    • (2001) Immunity , vol.15 , pp. 47-58
    • López-Rodríguez, C.1    Aramburu, J.2    Jin, L.3    Rakeman, A.S.4    Michino, M.5    Rao, A.6
  • 2
    • 33947218932 scopus 로고    scopus 로고
    • The Drosophila NFAT homolog is involved in salt stress tolerance
    • Keyser, P., Borge-Renberg, K. and Hultmark, D., The Drosophila NFAT homolog is involved in salt stress tolerance. Insect Biochem.Mol. Biol. 2007. 37: 356-362.
    • (2007) Insect Biochem.Mol. Biol. , vol.37 , pp. 356-362
    • Keyser, P.1    Borge-Renberg, K.2    Hultmark, D.3
  • 3
    • 0033594887 scopus 로고    scopus 로고
    • NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun
    • Lopez-Rodríguez, C., Aramburu, J., Rakeman, A. S. and Rao, A., NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun. Proc. Natl. Acad. Sci. USA 1999. 96: 7214-7219.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7214-7219
    • Lopez-Rodríguez, C.1    Aramburu, J.2    Rakeman, A.S.3    Rao, A.4
  • 5
    • 33846839229 scopus 로고    scopus 로고
    • A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis
    • O'Connor, R. S., Mills, S. T., Jones, K. A., Ho, S. N. and Pavlath, G. K., A combinatorial role for NFAT5 in both myoblast migration and differentiation during skeletal muscle myogenesis. J. Cell Sci. 2007. 120: 149-159.
    • (2007) J. Cell Sci. , vol.120 , pp. 149-159
    • O'Connor, R.S.1    Mills, S.T.2    Jones, K.A.3    Ho, S.N.4    Pavlath, G.K.5
  • 6
    • 0037111409 scopus 로고    scopus 로고
    • The osmoprotective function of the NFAT5 transcription factor in T cell development and activation
    • Trama, J., Go, W. Y. and Ho, S. N., The osmoprotective function of the NFAT5 transcription factor in T cell development and activation. J. Immunol. 2002. 169: 5477-5488.
    • (2002) J. Immunol. , vol.169 , pp. 5477-5488
    • Trama, J.1    Go, W.Y.2    Ho, S.N.3
  • 10
    • 70449625015 scopus 로고    scopus 로고
    • The role of Toll-like receptor in rheumatoid arthritis
    • Huanq, Q. Q. and Pope, R. M., The role of Toll-like receptor in rheumatoid arthritis. Curr. Rheumatol. Rep. 2009. 11: 357-364.
    • (2009) Curr. Rheumatol. Rep. , vol.11 , pp. 357-364
    • Huanq, Q.Q.1    Pope, R.M.2
  • 11
  • 12
    • 48749131177 scopus 로고    scopus 로고
    • CREB has a context-dependent role in activity-regulated transcription andmaintains neuronal cholesterol homeostasis
    • Lemberger, T., Parkitna, J. R., Chai, M., Schütz, G. and Engblom, D., CREB has a context-dependent role in activity-regulated transcription andmaintains neuronal cholesterol homeostasis. FASEB J. 2008. 22: 2872- 2879.
    • (2008) FASEB J , vol.22 , pp. 2872-2879
    • Lemberger, T.1    Parkitna, J.R.2    Chai, M.3    Schütz, G.4    Engblom, D.5
  • 13
    • 44449116119 scopus 로고    scopus 로고
    • Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells
    • Kondo, T., Sheets, P. L., Zopf, D. A., Aloor, H. L., Cummins, T. R., Chan, R. J. and Hashino, E., Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells. Proc. Natl. Acad. Sci. USA 2008. 105: 5780-5785.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 5780-5785
    • Kondo, T.1    Sheets, P.L.2    Zopf, D.A.3    Aloor, H.L.4    Cummins, T.R.5    Chan, R.J.6    Hashino, E.7
  • 14
    • 0037195922 scopus 로고    scopus 로고
    • Fyn and p38 signaling are both required for maximal hypertonic activation of the osmotic response element-binding protein/tonicityresponsive enhancer-binding protein (OREBP/TonEBP)
    • Ko, B. C., Lam, A. K., Kapus, A., Fan, L., Chung, S. K. and Chung, S. S., Fyn and p38 signaling are both required for maximal hypertonic activation of the osmotic response element-binding protein/tonicityresponsive enhancer-binding protein (OREBP/TonEBP). J. Biol. Chem. 2002. 277: 46085-46092.
    • (2002) J. Biol. Chem. , vol.277 , pp. 46085-46092
    • Ko, B.C.1    Lam, A.K.2    Kapus, A.3    Fan, L.4    Chung, S.K.5    Chung, S.S.6
  • 16
    • 20644433073 scopus 로고    scopus 로고
    • ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity
    • Matsuzawa, A., Saegusa, K., Noguchi, T., Sadamitsu, C., Nishitoh, H., Nagai, S., Koyasu, S. et al., ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity. Nat. Immunol. 2005. 6: 587-592.
    • (2005) Nat. Immunol. , vol.6 , pp. 587-592
    • Matsuzawa, A.1    Saegusa, K.2    Noguchi, T.3    Sadamitsu, C.4    Nishitoh, H.5    Nagai, S.6    Koyasu, S.7
  • 17
    • 27144524287 scopus 로고    scopus 로고
    • Hypertonic induction of COX-2 in collecting duct cells by reactive oxygen species of mitochondrial origin
    • Yang, T., Zhang, A., Honeggar, M., Kohan, D. E., Mizel, D., Sanders, K., Hoidal, J. R. et al., Hypertonic induction of COX-2 in collecting duct cells by reactive oxygen species of mitochondrial origin. J. Biol. Chem. 2005. 280: 34966-34973.
    • (2005) J. Biol. Chem. , vol.280 , pp. 34966-34973
    • Yang, T.1    Zhang, A.2    Honeggar, M.3    Kohan, D.E.4    Mizel, D.5    Sanders, K.6    Hoidal, J.R.7
  • 18
    • 33646595343 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species contribute to high NaCl-induced activation of the transcription factor TonEBP/OREBP
    • Zhou, X., Ferraris, J. D. and Burg, M. B., Mitochondrial reactive oxygen species contribute to high NaCl-induced activation of the transcription factor TonEBP/OREBP. Am. J. Physiol. Renal Physiol. 2006. 290: 1169-1176.
    • (2006) Am. J. Physiol. Renal Physiol. , vol.290 , pp. 1169-1176
    • Zhou, X.1    Ferraris, J.D.2    Burg, M.B.3
  • 19
    • 33645395280 scopus 로고    scopus 로고
    • Allopurinol modulates reactive oxygen species generation and Ca2+ overload in ischemia-reperfused heart and hypoxia-reoxygenated cardiomyocytes
    • Kang, S. M., Lim, S., Song, H., Chang, W., Lee, S., Bae, S. M., Chung, J. H. et al., Allopurinol modulates reactive oxygen species generation and Ca2+ overload in ischemia-reperfused heart and hypoxia-reoxygenated cardiomyocytes. Eur. J. Pharmacol. 2006. 535: 212-219.
    • (2006) Eur. J. Pharmacol. , vol.535 , pp. 212-219
    • Kang, S.M.1    Lim, S.2    Song, H.3    Chang, W.4    Lee, S.5    Bae, S.M.6    Chung, J.H.7
  • 20
    • 70350573933 scopus 로고    scopus 로고
    • A non-redundant role for MKP5 in limiting ROS production and preventing LPS-induced vascular injury
    • Qian, F., Deng, J., Cheng, N., Welch, E. J., Zhang, Y., Malik, A. B., Flavell, R. A. et al., A non-redundant role for MKP5 in limiting ROS production and preventing LPS-induced vascular injury. EMBO J. 2009. 28: 2896-2907.
    • (2009) EMBO J , vol.28 , pp. 2896-2907
    • Qian, F.1    Deng, J.2    Cheng, N.3    Welch, E.J.4    Zhang, Y.5    Malik, A.B.6    Flavell, R.A.7
  • 21
    • 33747075792 scopus 로고    scopus 로고
    • Mechanisms of endotoxin-induced NO, IL-6, and TNF-alpha production in activated rat hepatic stellate cells: role of p38 MAPK
    • Thirunavukkarasu, C., Watkins, S. C. and Gandhi, C. R., Mechanisms of endotoxin-induced NO, IL-6, and TNF-alpha production in activated rat hepatic stellate cells: role of p38 MAPK. Hepatology 2006. 44: 389-398.
    • (2006) Hepatology , vol.44 , pp. 389-398
    • Thirunavukkarasu, C.1    Watkins, S.C.2    Gandhi, C.R.3
  • 22
    • 0028855704 scopus 로고
    • Tissue- and cell-specific expression of mouse xanthine oxidoreductase gene in vivo: regulation by bacterial lipopolysaccharide
    • Kurosaki, M., Li, Calzi, M., Scanziani, E., Garattini, E. and Terao, M., Tissue- and cell-specific expression of mouse xanthine oxidoreductase gene in vivo: regulation by bacterial lipopolysaccharide. Biochem. J. 1995. 306: 225-234.
    • (1995) Biochem. J. , vol.306 , pp. 225-234
    • Kurosaki, M.1    Li2    Calzi, M.3    Scanziani, E.4    Garattini, E.5    Terao, M.6
  • 23
    • 4344627821 scopus 로고    scopus 로고
    • Endogenous ligands of Toll-like receptors
    • Tsan, M. F. and Gao, B., Endogenous ligands of Toll-like receptors. J. Leukoc. Biol. 2004. 76: 514-519.
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 514-519
    • Tsan, M.F.1    Gao, B.2
  • 24
    • 0034443265 scopus 로고    scopus 로고
    • Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: involvement of Toll-like receptors
    • Tsuji, S., Matsumoto, M., Takeuchi, O., Akira, S., Azuma, I., Hayashi, A., Toyoshima, K. et al., Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: involvement of Toll-like receptors. Infect. Immun. 2000. 68: 6883-6890.
    • (2000) Infect. Immun. , vol.68 , pp. 6883-6890
    • Tsuji, S.1    Matsumoto, M.2    Takeuchi, O.3    Akira, S.4    Azuma, I.5    Hayashi, A.6    Toyoshima, K.7
  • 25
    • 38749137794 scopus 로고    scopus 로고
    • Reactive oxygen species produced by NADPH oxidase, xanthine oxidase, and mitochondrial electron transport system mediate heat shock-induced MMP-1 and MMP-9 expression
    • Shin,M. H., Moon, Y. J., Seo, J. E., Lee, Y., Kim, K. H. and Chung, J. H., Reactive oxygen species produced by NADPH oxidase, xanthine oxidase, and mitochondrial electron transport system mediate heat shock-induced MMP-1 and MMP-9 expression. Free Radic. Biol. Med. 2008. 44: 635-645.
    • (2008) Free Radic. Biol. Med. , vol.44 , pp. 635-645
    • Shin, M.H.1    Moon, Y.J.2    Seo, J.E.3    Lee, Y.4    Kim, K.H.5    Chung, J.H.6
  • 26
    • 28444498126 scopus 로고    scopus 로고
    • Intracellular water homeostasis and the mammalian cellular osmotic stress response
    • Ho, S. N., Intracellular water homeostasis and the mammalian cellular osmotic stress response. J. Cell Physiol. 2006. 206: 9-15.
    • (2006) J. Cell Physiol. , vol.206 , pp. 9-15
    • Ho, S.N.1
  • 27
    • 0041378062 scopus 로고    scopus 로고
    • Xanthine oxidoreductase is central to the evolution and function of the innate immune system
    • Vorbach, C., Harrison, R. and Capecchi, M. R., Xanthine oxidoreductase is central to the evolution and function of the innate immune system. Trends Immunol. 2003. 24: 512-517.
    • (2003) Trends Immunol , vol.24 , pp. 512-517
    • Vorbach, C.1    Harrison, R.2    Capecchi, M.R.3
  • 28
    • 0029900435 scopus 로고    scopus 로고
    • Molecular cloning and characterization of the human xanthine dehydrogenase gene (XDH)
    • Xu, P., Huecksteadt, T. P. and Hoidal, J. R., Molecular cloning and characterization of the human xanthine dehydrogenase gene (XDH). Genomics 1996. 34: 173-180.
    • (1996) Genomics , vol.34 , pp. 173-180
    • Xu, P.1    Huecksteadt, T.P.2    Hoidal, J.R.3
  • 29
    • 0018854404 scopus 로고
    • Xanthine oxidase increase in polymorphonuclear leucocytes and macrophages in mice in three pathological situations
    • Tubaro, E., Lotti, B., Santiangeli, C. and Cavallo, G., Xanthine oxidase increase in polymorphonuclear leucocytes and macrophages in mice in three pathological situations. Biochem. Pharmacol. 1980. 29: 1945-1948.
    • (1980) Biochem. Pharmacol. , vol.29 , pp. 1945-1948
    • Tubaro, E.1    Lotti, B.2    Santiangeli, C.3    Cavallo, G.4
  • 30
    • 0030915245 scopus 로고    scopus 로고
    • Induction of nitric oxide synthesis and xanthine oxidase and their roles in the antimicrobial mechanism against Salmonella typhimurium infection in mice
    • Umezawa, K., Akaike, T., Fujii, S., Suga, M., Setoguchi, K., Ozawa, A. and Maeda, H., Induction of nitric oxide synthesis and xanthine oxidase and their roles in the antimicrobial mechanism against Salmonella typhimurium infection in mice. Infect. Immun. 1997. 65: 2932-2940.
    • (1997) Infect. Immun. , vol.65 , pp. 2932-2940
    • Umezawa, K.1    Akaike, T.2    Fujii, S.3    Suga, M.4    Setoguchi, K.5    Ozawa, A.6    Maeda, H.7
  • 31
    • 84882958162 scopus 로고    scopus 로고
    • Reactive oxygen species regulate context-dependent inhibition of NFAT5 target genes
    • Kim, N. H., Hong, B. K., Choi, S. Y., Kwon, H. M., Cho, C. S., Yi, E. C. and Kim, W. U., Reactive oxygen species regulate context-dependent inhibition of NFAT5 target genes. Exp. Mol. Med. 2013. 45: e32.
    • (2013) Exp. Mol. Med. , vol.45
    • Kim, N.H.1    Hong, B.K.2    Choi, S.Y.3    Kwon, H.M.4    Cho, C.S.5    Yi, E.C.6    Kim, W.U.7
  • 32
    • 0035701127 scopus 로고    scopus 로고
    • Oxidative stress in heart failure: the role of mitochondria
    • Tsutsui, H., Oxidative stress in heart failure: the role of mitochondria. Intern. Med. 2001. 40: 1177-1182.
    • (2001) Intern. Med. , vol.40 , pp. 1177-1182
    • Tsutsui, H.1
  • 33
    • 0037453094 scopus 로고    scopus 로고
    • Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation
    • Spiekermann, S., Landmesser, U., Dikalov, S., Bredt, M., Gamez, G., Tatge, H., Reepschläger, N. et al., Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation. Circulation 2003. 107: 1383-1389.
    • (2003) Circulation , vol.107 , pp. 1383-1389
    • Spiekermann, S.1    Landmesser, U.2    Dikalov, S.3    Bredt, M.4    Gamez, G.5    Tatge, H.6    Reepschläger, N.7
  • 34
    • 0033535974 scopus 로고    scopus 로고
    • Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis
    • von Harsdorf, R., Li, P. F. and Dietz, R., Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis. Circulation 1999. 99: 2934-2941.
    • (1999) Circulation , vol.99 , pp. 2934-2941
    • von Harsdorf, R.1    Li, P.F.2    Dietz, R.3
  • 35
    • 27944474377 scopus 로고    scopus 로고
    • Redox-dependent transcriptional regulation
    • Liu, H., Colavitti, R., Rovira, II. and Finkel, T., Redox-dependent transcriptional regulation. Circ. Res. 2005. 97: 967-974.
    • (2005) Circ. Res. , vol.97 , pp. 967-974
    • Liu, H.1    Colavitti, R.2    Rovira, I.I.3    Finkel, T.4
  • 37
    • 0027960150 scopus 로고
    • Effects of allopurinol on in vivo suppression of arthritis in mice and ex vivo modulation of phagocytic production of oxygen radicals in whole human blood
    • Miesel, R., Zuber, M., Sanocka, D., Graetz, R. and Kroeger, H., Effects of allopurinol on in vivo suppression of arthritis in mice and ex vivo modulation of phagocytic production of oxygen radicals in whole human blood. Inflammation 1994. 18: 597-612.
    • (1994) Inflammation , vol.18 , pp. 597-612
    • Miesel, R.1    Zuber, M.2    Sanocka, D.3    Graetz, R.4    Kroeger, H.5
  • 38
    • 35748937946 scopus 로고    scopus 로고
    • Transcriptional activator TonE-binding protein in cellular protection and differentiation
    • Kim, J. A., Jeon, U. S., Kwon, M. S., Lim, S. W. and Kwon, H. M., Transcriptional activator TonE-binding protein in cellular protection and differentiation. Methods Enzymol. 2007. 428: 253-267.
    • (2007) Methods Enzymol , vol.428 , pp. 253-267
    • Kim, J.A.1    Jeon, U.S.2    Kwon, M.S.3    Lim, S.W.4    Kwon, H.M.5
  • 39
    • 23344435003 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase is necessary for gemcitabine-induced cytotoxicity in human pancreatic cancer cells
    • Koizumi, K., Tanno, S., Nakano, Y., Habiro, A., Izawa, T., Mizukami, Y., Okumura, T. et al., Activation of p38 mitogen-activated protein kinase is necessary for gemcitabine-induced cytotoxicity in human pancreatic cancer cells. Anticancer Res. 2005. 25: 3347-3353.
    • (2005) Anticancer Res , vol.25 , pp. 3347-3353
    • Koizumi, K.1    Tanno, S.2    Nakano, Y.3    Habiro, A.4    Izawa, T.5    Mizukami, Y.6    Okumura, T.7
  • 40
    • 34248559599 scopus 로고    scopus 로고
    • Gene splicing and mutagenesis by PCRdriven overlap extension
    • Heckman, K. L. and Pease, L. R., Gene splicing and mutagenesis by PCRdriven overlap extension. Nat. Protoc. 2007. 2: 924-932.
    • (2007) Nat. Protoc. , vol.2 , pp. 924-932
    • Heckman, K.L.1    Pease, L.R.2
  • 41
    • 0029098592 scopus 로고
    • Improved detection of nitric oxide radical (NO.) production in an activated macrophage culture with a radical scavenger, carboxy PTIO and Griess reagent
    • Amano, F. and Noda, T., Improved detection of nitric oxide radical (NO.) production in an activated macrophage culture with a radical scavenger, carboxy PTIO and Griess reagent. FEBS Lett. 1995. 368: 425-428.
    • (1995) FEBS Lett , vol.368 , pp. 425-428
    • Amano, F.1    Noda, T.2
  • 42
    • 84861755093 scopus 로고    scopus 로고
    • A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis
    • Yoo, S. A., You, S., Yoon, H. J., Kim, D. H., Kim, H. S., Lee, K., Ahn, J. H. et al., A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis. J. Exp. Med. 2012. 209: 871-886.
    • (2012) J. Exp. Med. , vol.209 , pp. 871-886
    • Yoo, S.A.1    You, S.2    Yoon, H.J.3    Kim, D.H.4    Kim, H.S.5    Lee, K.6    Ahn, J.H.7
  • 43
    • 59649090734 scopus 로고    scopus 로고
    • Role of placenta growth factor and its receptor flt-1 in rheumatoid inflammation: a link between angiogenesis and inflammation
    • Yoo, S. A., Yoon, H. J., Kim, H. S., Chae, C. B., De Falco, S., Cho, C. S. and Kim, W. U., Role of placenta growth factor and its receptor flt-1 in rheumatoid inflammation: a link between angiogenesis and inflammation. Arthritis Rheum. 2009. 60: 345-354.
    • (2009) Arthritis Rheum , vol.60 , pp. 345-354
    • Yoo, S.A.1    Yoon, H.J.2    Kim, H.S.3    Chae, C.B.4    De Falco, S.5    Cho, C.S.6    Kim, W.U.7
  • 44
    • 74849127389 scopus 로고    scopus 로고
    • Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate
    • Kong, J. S., Yoo, S. A., Kim, H. S., Kim, H. A., Yea, K., Ryu, S. H., Chung, Y. J. et al., Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by sulforaphane, a naturally occurring isothiocyanate. Arthritis Rheum. 2010. 62: 159-170.
    • (2010) Arthritis Rheum , vol.62 , pp. 159-170
    • Kong, J.S.1    Yoo, S.A.2    Kim, H.S.3    Kim, H.A.4    Yea, K.5    Ryu, S.H.6    Chung, Y.J.7


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