Cis- and trans-acting factors regulating transcription of the BGT1 gene in response to hypertonicity

American Journal of Physiology - Renal Physiology

Volumn 274, Issue 4 43-4, 1998, Pages

  Miyakawa, Hiroshi ^a   Woo, Seung Kyoon ^a   Chen, Ching Pu ^a   Dahl, Stephen C ^a   Handler, Joseph S ^a   Kwon, H Moo ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Betaine aminobutyric acid transporter; Compatible osmolytes; In vivo footprinting

Indexed keywords

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA BINDING; GENE CONTROL; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RNA TRANSLATION; TRANSCRIPTION REGULATION;

EID: 0031958591     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1998.274.4.f753     Document Type: Article

References (33)

1. Albertyn, J., S. Hohmann, J. M. Thevelein, and B. A. Prior. GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolality glycerol response pathway. Mol. Cell. Biol. 14: 4135-4144, 1994.
2. Bagnasco, S. M., H. R. Murphy, J. J. Bedford, and M. B. Burg. Osmoregulation by slow changes in aldose reductase and rapid changes in sorbitol flux. Am. J. Physiol. 254 (Cell Physiol. 23): C788-C792, 1988.
3. Cowley, B. D., J. D. Ferraris, D. Carper, and M. B. Burg. In vivo osmoregulation of aldose reductase mRNA, protein and sorbitol in renal medulla. Am. J. Physiol. 258 (Renal Fluid Electrolyte Physiol. 27): F154-F161, 1990.
4. Daoudal, S., C. Tournaire, A. Halere, G. Veyssiere, and C. Jean. Isolation of the mouse aldose reductase promoter and identification of a tonicity-responsive element. J. Biol. Chem. 272: 2615-2619, 1997.
5. Ferraris, J. D., C. K. Williams, K. Jung, J. J. Bedford, M. B. Burg, and A. Garcia-Perez. ORE, a eukaryotic minimal essential osmotic response element. J. Biol. Chem. 271: 18318-18321, 1996.
6. Garcia-Perez, A., and M. B. Burg. Renal medullary organic osmolytes. Physiol. Rev. 71: 1081-1115, 1991.
7. Giannini, G., L. D. Marcotullio, F. Zazzeroni, E. Alesse, M. Zani, A. T'Ang, V. Sorrentino, I. Screpanti, L. Frati, and A. Gulino. 2-Aminopurine unravels a role for pRB in the regulation of gene expression by transforming growth factor β. J. Biol. Chem. 272: 5313-5319, 1997.
8. Karin, M., and T. Hunter. Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus. Curr. Biol. 5: 747-757, 1995.
9. Kitamura, H., A. Yamauchi, T. Nakanishi, Y. Takamitsu, T. Sugiura, A. Akagi, T. Moriyama, M. Horio, and E. Imai. Effects of inhibition of myo-inositol transport on MDCK cells under hypertonic environment. Am. J. Physiol. 272 (Renal Physiol. 41): F267-F272, 1997.
10. Ko, B. C. B., B. Ruepp, K. M. Bohren, K. H. Gabbay, and S. S. M. Chung. Identification and characterization of multiple osmotic response sequences in the human aldose reductase gene. J. Biol. Chem. 272: 16431-16437, 1997.
11. Kultz, D., A. Garcia-Perez, J. D. Ferraris, and M. B. Burg. Distinct regulation of osmoprotective genes in yeast and mammals. J. Biol. Chem. 272: 13165-13170, 1997.
12. Kwon, H. M., and J. S. Handler. Cell volume regulated transporters of compatible osmolytes. Curr. Opin. Cell Biol. 1: 465-471, 1995.
13. Kwon, H. M., I. Takahito, J. S. Rim, and J. S. Handler. The MAP kinase cascade is not essential for transcriptional stimulation of osmolyte transporter genes. Biochem. Biophys. Res. Commun. 213: 975-979, 1995.
14. +/myo-inositol cotransporter, a hypertonicity stress protein. J. Biol. Chem. 267: 6297-6301, 1992.
15. Martial, S., S. R. Price, and J. M. Sands. Regulation of aldose reductase, sorbitol dehydrogenase, and taurine cotransporter mRNA in rat medulla. J. Am. Soc. Nephrol. 5: 1971-1978, 1995.
16. Miyai, A., A. Yamauchi, T. Moriyama, T. Kaneko, M. Takenaka, T. Sugiura, H. Kitamura, A. Ando, M. Tohyama, S. Shimada, E. Imai, and T. Kamata. Expression of betaine transporter mRNA: Its unique localization and rapid regulation in rat kidney. Kidney Int. 50: 819-827, 1996.
17. --dependent betaine transporter in rat renal medulla. Am. J. Physiol. 272 (Renal Physiol. 41): F100-F106, 1997.
18. Mueller, P. R., P. A. Garrity, and B. Wold, B. Ligation-mediated PCR for genomic sequencing and footprinting. In: Current Protocols in Molecular Biology, edited by F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and S. Struhl. New York: Wiley, 1992, vol. 2, p. 15.5.1-15.5.26.
19. Posas, F., and H. Saito. Osmotic activation of the HOG MAPK pathway via Ste 11p MAPKKK: scaffold role of Pbs2p MAPKK. Science 276: 1702-1705, 1997.
20. Rim, J. S., S. Tanawattanacharoen, M. Takenaka, J. S. Handler, and H. M. Kwon. The canine sodium/myo-inositol cotransporter gene: Structural organization and characterization of the promoter. Arch. Biochem. Biophys. 341: 193-199 1997.
21. Ruep, B., K. M. Bohren, and K. H. Gabbay. Characterization of the osmotic response element of the human aldose reductase gene promoter. Proc. Natl. Acad. Sci. USA 93: 8624-8629, 1995.
22. Sheikh-Hamad, D., J. D. Ferraris, J. Dragolovich, H. G. Preuss, M. B. Burg, and A. Garcia-Perez. CD9 antigen mRNA is induced by hypertonicity in two renal epithelial cell lines. Am. J. Physiol. 270 (Cell Physiol. 39): C253-C258, 1996.
23. Sone, M., A. Ohno, G. J. Albrecht, K. Thurau, and F. Beck. Restoration of urine concentrating ability and accumulation of medullary osmolytes after chronic diuresis. Am. J. Physiol. 269 (Renal Fluid Electrolyte Physiol. 38): F480-F490, 1995.
24. Takenaka, M., A. S. Preston, H. M. Kwon, and J. S. Handler. The tonicity-sensitive element that mediates increased transcription of the betaine transporter gene in response to hypertonic stress. J. Biol. Chem. 269: 29379-29381, 1994.
25. Tanaka, M. Modulation of promoter occupancy by cooperative DNA binding and activation-domain function is a major determinant of transcriptional regulation by activators in vivo. Proc. Natl. Acad. Sci. USA 93: 4311-4315, 1996.
26. --dependent taurine transporter that is regulated by hypertonicity. Proc. Natl. Acad. Sci. USA 89: 8230-8234, 1992.
27. Uchida, S., T. Nakanishi, H. M. Kwon, A. S. Preston, and J. S. Handler. Taurine behaves as an osmolyte in Madin-Darby canine kidney cells. J. Clin. Invest. 88: 656-662, 1991.
28. --dependent betaine transporter in Madin-Darby canine kidney cells by increasing transcription of the transporter gene. J. Clin. Invest. 91: 1604-1607, 1993.
29. Weinhold, P. A., N. Thanukrishna, and L. Anderson. Antagonistic relationship between myo-inositol and 2-O,C-methylene-myo-inositol in animals. Proc. Soc. Exp. Biol. Med. 112: 165-168, 1963.
30. Yamauchi, A., H. M. Kwon, S. Uchida, A. S. Preston, and J. S. Handler. Myo-inositol and betaine transporters regulated by tonicity are basolateral in MDCK cells. Am. J. Physiol. 261 (Renal Fluid Electrolyte Physiol. 30): F197-F202, 1991.
31. --dependent betaine transporter that is regulated by hypertonicity. J. Biol. Chem. 267: 649-652, 1992.
32. Yancey, P. H., M. B. Burg, and S. M. Bagnasco. Effects of NaCl, glucose, and aldose reductase inhibitors on cloning efficiency of renal medullary cells. Am. J. Physiol. 258 (Cell Physiol. 27): C156-C163, 1990.
33. Yancey, P. H., M. E. Clark, S. C. Hand, R. D. Bowlus, and G. N. Somero. Living with water stress: evolution of osmolyte system. Science 217: 1214-1222, 1982.