RNA adenosine deaminase ADAR1 deficiency leads to increased activation of protein kinase PKR and reduced vesicular stomatitis virus growth following interferon treatment

Virology

Volumn 396, Issue 2, 2010, Pages 316-322

  Li, Zhiqun ^a   Wolff, Karen C ^a   Samuel, Charles E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

ADAR1; PKR; Type I IFN; Vesicular stomatitis virus

Indexed keywords

ADENOSINE DEAMINASE; INTERFERON; PROTEIN ADAR1; PROTEIN KINASE R; PROTEIN P110; RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; FIBROBLAST; GENE OVEREXPRESSION; GROWTH INHIBITION; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA VIRUS INFECTION; VESICULAR STOMATITIS VIRUS; VIROGENESIS; VIRUS INHIBITION;

ADENOSINE DEAMINASE; BLOTTING, WESTERN; CELL PROLIFERATION; EIF-2 KINASE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; INTERFERON-ALPHA; INTERFERON-BETA; RHABDOVIRIDAE INFECTIONS; STAT1 TRANSCRIPTION FACTOR; VESICULOVIRUS;

VESICULAR STOMATITIS VIRUS;

EID: 70749147276     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2009.10.026     Document Type: Article

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