Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP

Genes and Development

Volumn 29, Issue 12, 2015, Pages 1285-1297

  Chen, Qian ^a   Zhang, Nailing ^a   Xie, Rui ^a   Wang, Wei ^a   Cai, Jing ^a   Choi, Kyung Suk ^a   David, Karen Kate ^a   Huang, Bo ^a   Yabuta, Norikazu ^b   Nojima, Hiroshi ^b   Anders, Robert A ^a   Pan, Duojia ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

14 3 3; Hippo signaling; Phosphorylation; Tumorigenesis; YAP oncoprotein

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; CYSTEINE RICH PROTEIN 61; MUTANT PROTEIN; PROTEIN; PROTEIN LATS1; PROTEIN LATS2; PROTEIN YAP; SURVIVIN; TAZ PROTEIN; UNCLASSIFIED DRUG; HIPPO PROTEIN, MOUSE; PHOSPHOPROTEIN; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; YAP PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BIRC5 GENE; BODY WEIGHT; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE MUTATION; HIPPO SIGNALING PATHWAY; HOMEOSTASIS; LIVER; LIVER SIZE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; YAP GENE; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL NUCLEUS; CYTOPLASM; FEEDBACK SYSTEM; GENE EXPRESSION REGULATION; GENE TARGETING; GENETICS; METABOLISM; MUTATION; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TRANSPORT;

MAMMALIA; MUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL NUCLEUS; CELLS, CULTURED; CYTOPLASM; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCK-IN TECHNIQUES; HOMEOSTASIS; LIVER; MICE; MICE, INBRED C57BL; MUTATION; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 84933531136     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.264234.115     Document Type: Article

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